Pulmonary artery index. A nonpredictor of operative survival in patients undergoing modified Fontan repair.

abstract：:The effect of the ouabain-quinidine interaction was examined in 10 conscious dogs. Left ventricular (LV) pressure, LV dP/dt, LV diameter and left atrial (LA) diameter were measured with high-fidelity micromanometers and sonomicrometer crystals. Ouabain, 0.025 mg/kg, significantly (p less than 0.05) increased LV dP/dt,...

journal_title：Circulation

authors： Goldman S,Hager WD,Olajos M,Perrier D,Mayersohn M

更新日期：1983-05-01 00:00:00

abstract：:Myocardial lactate production indicates anaerobic metabolism resulting from hypoxia or anoxia. Clinically, myocardial lactate extraction of less than 10% has also been used as an indicator of ischemia. Sixteen healthy young male volunteers underwent coronary sinus and aterial catheterization. A coronary sinus pacing c...

journal_title：Circulation

authors： Gertz EW,Wisneski JA,Neese R,Houser A,Korte R,Bristow JD

更新日期：1980-02-01 00:00:00

abstract：BACKGROUND:Regional sympathetic denervation, such as that produced by a myocardial infarction, causes electrophysiological heterogeneity in the ventricles. The purpose of this study was to test the hypothesis that such denervation could cause drugs to exert heterogeneous myocardial effects. METHODS AND RESULTS:Sympath...

journal_title：Circulation

authors： Stanton MS,Zipes DP

更新日期：1991-10-01 00:00:00

abstract：BACKGROUND:The term "concealed conduction" is used in electrocardiography when a proximal (atrial or ventricular) impulse penetrates the atrioventricular (AV) node but fails to traverse it completely. Its penetration into the node is inferred by its after effects on the propagation of succeeding impulses. Concealed AV ...

journal_title：Circulation

authors： Liu Y,Zeng W,Delmar M,Jalife J

更新日期：1993-10-01 00:00:00

abstract：BACKGROUND:Long-term rapid atrial pacing may result in atrial fibrillation (AF) in dogs. Whether there is histological evidence for neural remodeling is unclear. METHOD AND RESULTS:We performed rapid right atrial pacing in 6 dogs for 111+/-76 days to induce sustained AF. Tissues from 6 healthy dogs were used as contro...

journal_title：Circulation

authors： Chang CM,Wu TJ,Zhou S,Doshi RN,Lee MH,Ohara T,Fishbein MC,Karagueuzian HS,Chen PS,Chen LS

更新日期：2001-01-02 00:00:00

abstract：BACKGROUND:The renin-angiotensin-aldosterone system is involved in the pathogenesis of atherosclerosis, partially because of its pro-oxidative properties. We questioned the effect and mechanisms of action of administration of aldosterone to apolipoprotein E-deficient (E(0)) mice on their macrophages and aorta oxidative...

journal_title：Circulation

authors： Keidar S,Kaplan M,Pavlotzky E,Coleman R,Hayek T,Hamoud S,Aviram M

更新日期：2004-05-11 00:00:00

abstract：BACKGROUND:The incidence and cause of sudden cardiac death (SCD) in athletes is debated with hypertrophic cardiomyopathy often reported as the most common cause. METHODS AND RESULTS:A database of all National Collegiate Athletic Association deaths (2003-2013) was developed. Additional information and autopsy reports w...

journal_title：Circulation

authors： Harmon KG,Asif IM,Maleszewski JJ,Owens DS,Prutkin JM,Salerno JC,Zigman ML,Ellenbogen R,Rao AL,Ackerman MJ,Drezner JA

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:Chronic heart failure (CHF) is associated with endothelial dysfunction including impaired endothelium-mediated, flow-dependent dilation (FDD). There is evidence for increased radical formation in CHF, raising the possibility that nitric oxide is inactivated by radicals, thereby impairing endothelial function...

journal_title：Circulation

authors： Hornig B,Arakawa N,Kohler C,Drexler H

更新日期：1998-02-03 00:00:00

abstract：BACKGROUND:The aim of this prospective, randomized study was to examine whether additional school exercise lessons would result in improved peak oxygen uptake (primary end point) and body mass index-standard deviation score, motor and coordinative abilities, circulating progenitor cells, and high-density lipoprotein ch...

journal_title：Circulation

authors： Walther C,Gaede L,Adams V,Gelbrich G,Leichtle A,Erbs S,Sonnabend M,Fikenzer K,Körner A,Kiess W,Bruegel M,Thiery J,Schuler G

更新日期：2009-12-01 00:00:00

abstract：BACKGROUND:Mechanisms favoring the occurrence of paroxysmal atrial fibrillation (PAF) are complex and poorly defined. This study was designed to analyze dynamic changes in autonomic tone preceding the onset of PAF in a large group of patients. METHODS AND RESULTS:Holter tapes from 77 unselected consecutive patients (6...

journal_title：Circulation

authors： Bettoni M,Zimmermann M

更新日期：2002-06-11 00:00:00

abstract：BACKGROUND:The use of cells derived from human induced pluripotent stem cells as cellular therapy for myocardial injury has yet to be examined in a large-animal model. METHODS AND RESULTS:Immunosuppressed Yorkshire pigs were assigned to 1 of 3 groups: A myocardial infarction group (MI group; distal left anterior desce...

journal_title：Circulation

authors： Xiong Q,Ye L,Zhang P,Lepley M,Tian J,Li J,Zhang L,Swingen C,Vaughan JT,Kaufman DS,Zhang J

更新日期：2013-03-05 00:00:00

abstract：BACKGROUND:Although phase 2 reentry is said to be responsible for initiation of ventricular tachycardia (VT) in Brugada syndrome, information about the activation sequence during VT is limited. METHODS AND RESULTS:We developed an experimental Brugada syndrome model using a canine isolated right ventricular preparation...

journal_title：Circulation

authors： Kimura M,Kobayashi T,Owada S,Ashikaga K,Higuma T,Sasaki S,Iwasa A,Motomura S,Okumura K

更新日期：2004-01-06 00:00:00

abstract：:Neutrophil activation and infiltration into the ischemic myocardium after reperfusion may limit the amount of salvageable myocardium (reperfusion injury). The effects of intravenous perfluorochemicals (Fluosol-DA) on infarct size, ventricular contractility, and neutrophil function were assessed in an occlusion-reperfu...

journal_title：Circulation

authors： Bajaj AK,Cobb MA,Virmani R,Gay JC,Light RT,Forman MB

更新日期：1989-03-01 00:00:00

abstract：BACKGROUND:Circumferential pulmonary vein ablation (CPVA) is effective in curing atrial fibrillation (AF), but new-onset left atrial tachycardia (AT) is a potential complication. We evaluated whether a modified CPVA approach including additional ablation lines on posterior wall and the mitral isthmus would reduce the i...

journal_title：Circulation

authors： Pappone C,Manguso F,Vicedomini G,Gugliotta F,Santinelli O,Ferro A,Gulletta S,Sala S,Sora N,Paglino G,Augello G,Agricola E,Zangrillo A,Alfieri O,Santinelli V

更新日期：2004-11-09 00:00:00

abstract：BACKGROUND:The myocardial velocity gradient (MVG) is a recent index of regional myocardial function derived from endocardial and epicardial velocities obtained by tissue Doppler imaging (TDI). This index might be useful for discriminating between physiological and pathological left ventricular hypertrophy (LVH) and for...

journal_title：Circulation

authors： Derumeaux G,Mulder P,Richard V,Chagraoui A,Nafeh C,Bauer F,Henry JP,Thuillez C

更新日期：2002-04-02 00:00:00

abstract：BACKGROUND:Increased consumption of sugar-sweetened beverages (SSBs) has been associated with an elevated risk of obesity, metabolic syndrome, and type II diabetes mellitus. However, the effects of SSB consumption on blood pressure (BP) are uncertain. The objective of this study was to determine the relationship betwee...

journal_title：Circulation

authors： Chen L,Caballero B,Mitchell DC,Loria C,Lin PH,Champagne CM,Elmer PJ,Ard JD,Batch BC,Anderson CA,Appel LJ

更新日期：2010-06-08 00:00:00

abstract：BACKGROUND:Polymorphonuclear leukocytes, particularly neutrophils, are important mediators of ischemia/reperfusion-induced myocardial and coronary vascular injury. The selectin family of glycoprotein receptors mediates neutrophil "rolling," a loose, transient adhesion to the coronary endothelium that precedes the firme...

journal_title：Circulation

authors： Gill EA,Kong Y,Horwitz LD

更新日期：1996-08-01 00:00:00

abstract：BACKGROUND:Although surgery is indicated in patients with mitral regurgitation (MR) when left ventricular (LV) end-systolic (LVES) dimension is >40 mm, LV ejection fraction may decrease after mitral valve surgery. We hypothesize that significant LV remodeling before surgery is not reflected by standard echocardiographi...

journal_title：Circulation

authors： Schiros CG,Dell'Italia LJ,Gladden JD,Clark D 3rd,Aban I,Gupta H,Lloyd SG,McGiffin DC,Perry G,Denney TS Jr,Ahmed MI

更新日期：2012-05-15 00:00:00

abstract：BACKGROUND:Surviving cells in the postinfarction border zone are subjected to intense fluctuations of their microenvironment. Recently, border zone cardiomyocytes have been specifically implicated in cardiac regeneration. Here, we defined their unique transcriptional and regulatory properties, and comprehensively valid...

journal_title：Circulation

authors： van Duijvenboden K,de Bakker DEM,Man JCK,Janssen R,Günthel M,Hill MC,Hooijkaas IB,van der Made I,van der Kraak PH,Vink A,Creemers EE,Martin JF,Barnett P,Bakkers J,Christoffels VM

更新日期：2019-09-09 00:00:00

abstract：BACKGROUND:Heparin administration is usually limited to intravenous or subcutaneous injection. Oral delivery of heparin is an alternative to this and has been in great demand for treating patients who are at a high risk of deep vein thrombosis or pulmonary embolism. In this study, new heparin derivatives were synthesiz...

journal_title：Circulation

authors： Lee Y,Nam JH,Shin HC,Byun Y

更新日期：2001-12-18 00:00:00

abstract：BACKGROUND:Data from single-center studies suggest that echocardiographic parameters of mechanical dyssynchrony may improve patient selection for cardiac resynchronization therapy (CRT). In a prospective, multicenter setting, the Predictors of Response to CRT (PROSPECT) study tested the performance of these parameters ...

journal_title：Circulation

authors： Chung ES,Leon AR,Tavazzi L,Sun JP,Nihoyannopoulos P,Merlino J,Abraham WT,Ghio S,Leclercq C,Bax JJ,Yu CM,Gorcsan J 3rd,St John Sutton M,De Sutter J,Murillo J

更新日期：2008-05-20 00:00:00

abstract：BACKGROUND:The synthetic catecholamine dobutamine increases stroke volume in normal subjects and in patients with congestive heart failure. In addition to its direct influence on myocardial contractility, dobutamine may significantly modulate vascular tone because of its alpha- and beta-adrenergic agonist activity. ME...

journal_title：Circulation

authors： Binkley PF,Murray KD,Watson KM,Myerowitz PD,Leier CV

更新日期：1991-09-01 00:00:00

abstract：BACKGROUND:NADH/NADPH oxidase is an important source of superoxide in the vasculature. Recently, we found that polymorphism of the gene p22phox, a critical component of this oxidase, is associated with a risk of coronary artery disease. The aim of this study was to investigate the localization of p22phox in human coron...

journal_title：Circulation

authors： Azumi H,Inoue N,Takeshita S,Rikitake Y,Kawashima S,Hayashi Y,Itoh H,Yokoyama M

更新日期：1999-10-05 00:00:00

abstract：BACKGROUND:It has been suggested that intracellular Ca2+ overload in cardiac myocytes leads to the development of diabetic cardiomyopathy. Troglitazone, an insulin-sensitizing agent, is a promising therapeutic agent for diabetes and has been shown to prevent diabetes-induced myocardial changes. To elucidate the underly...

journal_title：Circulation

authors： Nakajima T,Iwasawa K,Oonuma H,Imuta H,Hazama H,Asano M,Morita T,Nakamura F,Suzuki J,Suzuki S,Kawakami Y,Omata M,Okuda Y

更新日期：1999-06-08 00:00:00

abstract：BACKGROUND:Current American and European guidelines emphasize the importance of rate-control treatments in treating atrial fibrillation with a Class I recommendation, although data on the survival benefits of rate control are lacking. The goal of the present study was to investigate whether patients receiving rate-cont...

journal_title：Circulation

authors： Chao TF,Liu CJ,Tuan TC,Chen SJ,Wang KL,Lin YJ,Chang SL,Lo LW,Hu YF,Chen TJ,Chiang CE,Chen SA

更新日期：2015-10-27 00:00:00

abstract：:Although past reports have identified a variety of prognostic factors in patients with severe chronic heart failure, previous studies have not evaluated the interaction of prognostic variables and drug treatment. We analyzed the association of 30 clinical, hemodynamic, and biochemical variables with survival in 203 co...

journal_title：Circulation

authors： Lee WH,Packer M

更新日期：1986-02-01 00:00:00

abstract：BACKGROUND:Observational studies have shown better survival in patients undergoing coronary artery bypass grafting (CABG) with 2 arterial grafts compared with 1. However, whether a third arterial graft is associated with incremental benefit remains uncertain. We sought to analyze the outcomes of 3 versus 2 arterial gra...

journal_title：Circulation

authors： Rocha RV,Tam DY,Karkhanis R,Nedadur R,Fang J,Tu JV,Gaudino M,Royse A,Fremes SE

更新日期：2018-11-06 00:00:00

abstract：BACKGROUND:Heterogeneous electrophysiological properties, which may be due in part to autonomic innervation, are important in the maintenance of atrial fibrillation (AF). We hypothesized that heterogeneous sympathetic denervation with phenol would create a milieu for sustained AF. METHODS AND RESULTS:After the determi...

journal_title：Circulation

authors： Olgin JE,Sih HJ,Hanish S,Jayachandran JV,Wu J,Zheng QH,Winkle W,Mulholland GK,Zipes DP,Hutchins G

更新日期：1998-12-08 00:00:00

abstract：:A prospective electrocardiographic study was designed to establish baseline values for electrocardiographic measurements, with specific reference to the QT interval during infancy, and to test the "QT hypothesis" for the sudden infant death syndrome (SIDS). In this ongoing study, ECGs are recorded on the fourth day of...

journal_title：Circulation

authors： Schwartz PJ,Montemerlo M,Facchini M,Salice P,Rosti D,Poggio G,Giorgetti R

更新日期：1982-09-01 00:00:00

abstract：BACKGROUND:Although a major role of coronary thrombosis in the pathogenesis of unstable angina has been demonstrated, the results of a series of studies have suggested that activation of the hemostatic system may not be confined to ischemic episodes. The purpose of this study was to investigate the temporal relation be...

journal_title：Circulation

authors： Biasucci LM,Liuzzo G,Caligiuri G,Quaranta G,Andreotti F,Sperti G,van de Greef W,Rebuzzi AG,Kluft C,Maseri A

更新日期：1996-06-15 00:00:00