Pulmonary artery index. A nonpredictor of operative survival in patients undergoing modified Fontan repair.

abstract：BACKGROUND:Electrophysiological mechanisms by which adenosine may activate cardiac afferent neurons are unknown. Slow afterhyperpolarizations (AHPs) follow action potentials in a subset of vagal C afferents, rendering them inexcitable. The purpose of this study was to test the hypothesis that adenosine increases vagal ...

journal_title：Circulation

authors： Middlekauff HR,Doering A,Weiss JN

更新日期：2001-03-06 00:00:00

abstract：BACKGROUND:Integrins are involved in structural remodeling and tissue repair. This study aimed to elucidate the role of the beta-integrins in cardiac remodeling after myocardial infarction (MI). METHODS AND RESULTS:The MI model was created by ligation of the left anterior descending coronary artery in rats. We detecte...

journal_title：Circulation

authors： Sun M,Opavsky MA,Stewart DJ,Rabinovitch M,Dawood F,Wen WH,Liu PP

更新日期：2003-02-25 00:00:00

abstract：:Calcification of valvular bioprostheses in children is a major problem that has stimulated extensive research in our laboratory. In previous reports, we have shown that the rate of calcification could be reduced by decreasing the phosphate content in the tissue or by blocking calcification binding sites with Mg++ and/...

journal_title：Circulation

authors： Carpentier A,Nashef A,Carpentier S,Ahmed A,Goussef N

更新日期：1984-09-01 00:00:00

abstract：BACKGROUND:The incidence and cause of sudden cardiac death (SCD) in athletes is debated with hypertrophic cardiomyopathy often reported as the most common cause. METHODS AND RESULTS:A database of all National Collegiate Athletic Association deaths (2003-2013) was developed. Additional information and autopsy reports w...

journal_title：Circulation

authors： Harmon KG,Asif IM,Maleszewski JJ,Owens DS,Prutkin JM,Salerno JC,Zigman ML,Ellenbogen R,Rao AL,Ackerman MJ,Drezner JA

更新日期：2015-07-07 00:00:00

abstract：BACKGROUND:Data are conflicting over whether women have higher mortality than men after coronary artery bypass graft (CABG) surgery. Younger but not older women hospitalized for acute myocardial infarction have higher in-hospital mortality rates than men. We hypothesized that younger women also have higher in-hospital ...

journal_title：Circulation

authors： Vaccarino V,Abramson JL,Veledar E,Weintraub WS

更新日期：2002-03-12 00:00:00

abstract：BACKGROUND:Iron deficiency is common in patients with heart failure (HF) and is associated with reduced exercise capacity and poor outcomes. Whether correction of iron deficiency with (intravenous) ferric carboxymaltose (FCM) affects peak oxygen consumption [peak VO2], an objective measure of exercise intolerance in HF...

journal_title：Circulation

authors： van Veldhuisen DJ,Ponikowski P,van der Meer P,Metra M,Böhm M,Doletsky A,Voors AA,Macdougall IC,Anker SD,Roubert B,Zakin L,Cohen-Solal A,EFFECT-HF Investigators.

更新日期：2017-10-10 00:00:00

abstract：BACKGROUND:Postprandial angina pectoris has been recognized for more than two centuries and can be identified in up to 10% of patients with chronic ischemic heart disease. Redistribution of myocardial blood flow, from a region supplied by a severely stenotic coronary artery to those supplied by less diseased or normal ...

journal_title：Circulation

authors： Baliga RR,Rosen SD,Camici PG,Kooner JS

更新日期：1998-03-31 00:00:00

abstract：BACKGROUND:NO has been advocated as an adjunct to cardioplegia solutions. However, NO undergoes a rapid biradical reaction with superoxide anions to produce peroxynitrite (ONOO(-)). ONOO(-) in crystalloid cardioplegia solution induces injury to coronary endothelium and to systolic function after cardioplegia and reperf...

journal_title：Circulation

authors： Nakamura M,Thourani VH,Ronson RS,Velez DA,Ma XL,Katzmark S,Robinson J,Schmarkey LS,Zhao ZQ,Wang NP,Guyton RA,Vinten-Johansen J

更新日期：2000-11-07 00:00:00

abstract：BACKGROUND:Contrast agents can cause a reduction in renal function that may be due to the generation of reactive oxygen species. Conflicting evidence suggests that administration of the antioxidant acetylcysteine prevents this renal impairment. The action of other antioxidant agents has not been investigated. METHODS ...

journal_title：Circulation

authors： Spargias K,Alexopoulos E,Kyrzopoulos S,Iokovis P,Greenwood DC,Manginas A,Voudris V,Pavlides G,Buller CE,Kremastinos D,Cokkinos DV

更新日期：2004-11-02 00:00:00

abstract：BACKGROUND:Although both 201Tl scintigraphy and low-dose dobutamine echocardiography (LDDE) have been proposed as effective methods of assessing myocardial viability, their relative efficacies are unknown. The aim of the present study was to compare the two imaging techniques in the prediction of improvement of regiona...

journal_title：Circulation

authors： Arnese M,Cornel JH,Salustri A,Maat A,Elhendy A,Reijs AE,Ten Cate FJ,Keane D,Balk AH,Roelandt JR

更新日期：1995-06-01 00:00:00

abstract：:To define the prevalence, frequency and characteristics of premature ventricular complexes (PVCs) in adults free of recognizable heart disease, we performed 24-hour ambulatory electrocardiography on 101 subjects (51 men and 50 women, mean age 48.8 years) in whom physical examination, chest x-ray, ECG, echocardiogram, ...

journal_title：Circulation

authors： Kostis JB,McCrone K,Moreyra AE,Gotzoyannis S,Aglitz NM,Natarajan N,Kuo PT

更新日期：1981-06-01 00:00:00

abstract：BACKGROUND:Major gender-based differences in the incidence of ventricular tachyarrhythmia after myocardial infarction have been shown in humans. Although the underlying mechanisms are unclear, earlier studies suggest that estrogen receptor-mediated effects play a major role in this process. METHODS AND RESULTS:We exam...

journal_title：Circulation

authors： Korte T,Fuchs M,Arkudas A,Geertz S,Meyer R,Gardiwal A,Klein G,Niehaus M,Krust A,Chambon P,Drexler H,Fink K,Grohé C

更新日期：2005-05-10 00:00:00

abstract：BACKGROUND:This study compared the efficacy of ischemic preconditioning (IPC) and sodium-hydrogen exchanger (NHE)-1 inhibition to reduce infarct size (IS) induced by a 90-minute ischemic insult and examined the interaction between NHE-1 inhibition and IPC. METHODS AND RESULTS:In a canine infarct model, either IPC, pro...

journal_title：Circulation

authors： Gumina RJ,Buerger E,Eickmeier C,Moore J,Daemmgen J,Gross GJ

更新日期：1999-12-21 00:00:00

abstract：BACKGROUND:Combining 2 signals of cardiomyocyte injury, cardiac troponin I (cTnI) and T (cTnT), might overcome some individual pathophysiological and analytical limitations and thereby increase diagnostic accuracy for acute myocardial infarction with a single blood draw. We aimed to evaluate the diagnostic performance ...

journal_title：Circulation

authors： van der Linden N,Wildi K,Twerenbold R,Pickering JW,Than M,Cullen L,Greenslade J,Parsonage W,Nestelberger T,Boeddinghaus J,Badertscher P,Rubini Giménez M,Klinkenberg LJJ,Bekers O,Schöni A,Keller DI,Sabti Z,Puelacher C,

更新日期：2018-09-04 00:00:00

abstract：:The thienopyridines ticlopidine and clopidogrel are inhibitors of platelet function in vivo. Their mode of action has not been defined, but it appears that they require conversion to as yet unidentified metabolites that are noncompetitive antagonists of the platelet ADP receptor. Inhibition of platelet aggregation wit...

journal_title：Circulation

authors： Quinn MJ,Fitzgerald DJ

更新日期：1999-10-12 00:00:00

abstract：BACKGROUND:Prolonged survival of xenografted neonatal cardiomyocytes was achieved by blocking the CD28/B7 costimulatory pathway via CTLA4-Ig gene transfer. We examined the long-term survival of xenografted neonatal cardiomyocytes by adenovirus-mediated CTLA4-Ig expression and transient CD40 blockade with anti-CD40L mon...

journal_title：Circulation

authors： Li TS,Ito H,Kajiwara K,Hamano K

更新日期：2003-10-07 00:00:00

abstract：:Recent reports of selected observational studies and a meta-analysis have stirred controversy and have become the impetus for calls to abandon recommendations for reduced sodium intake by the US general population. A detailed review of these studies documents substantial methodological concerns that limit the usefulne...

journal_title：Circulation

authors： Whelton PK,Appel LJ,Sacco RL,Anderson CA,Antman EM,Campbell N,Dunbar SB,Frohlich ED,Hall JE,Jessup M,Labarthe DR,MacGregor GA,Sacks FM,Stamler J,Vafiadis DK,Van Horn LV

更新日期：2012-12-11 00:00:00

abstract：BACKGROUND:Increased carotid intimal-medial thickness (IMT) and coronary artery calcification (CAC) are used as 2 markers of early atherosclerosis. Our objectives were to assess whether increased IMT and CAC are related and to determine the relationship between cardiovascular risk factors and carotid IMT in young adult...

journal_title：Circulation

authors： Davis PH,Dawson JD,Mahoney LT,Lauer RM

更新日期：1999-08-24 00:00:00

abstract：BACKGROUND:As cardiovascular clinical trials improve in sophistication and therapies target specific cardiac mechanisms of death, a more objective and precise system to identify specific cause of death is needed. Ideally, sudden cardiac death would describe patients dying of ventricular tachycardia and ventricular fibr...

journal_title：Circulation

authors： Pratt CM,Greenway PS,Schoenfeld MH,Hibben ML,Reiffel JA

更新日期：1996-02-01 00:00:00

abstract：:Since platelet accumulation may be an important determinant of restenosis after angioplasty, the time course of 51Cr-labeled platelet accumulation after experimental angioplasty was evaluated in a deendothelialized, hypercholesterolemic rabbit preparation of atherosclerosis. Marked platelet accumulation (39.5 +/- 8.7 ...

journal_title：Circulation

authors： Wilentz JR,Sanborn TA,Haudenschild CC,Valeri CR,Ryan TJ,Faxon DP

更新日期：1987-03-01 00:00:00

abstract：:Continuous-wave Doppler echocardiography was used to estimate pulmonary artery pressures by measuring pulmonary regurgitant flow velocity in 21 patients with pulmonary hypertension (mean pulmonary artery pressure greater than or equal to 20 mm Hg) and 24 patients without pulmonary hypertension. The pulmonary regurgita...

journal_title：Circulation

authors： Masuyama T,Kodama K,Kitabatake A,Sato H,Nanto S,Inoue M

更新日期：1986-09-01 00:00:00

abstract：BACKGROUND:It has recently been shown that mitochondrial aldehyde dehydrogenase 2 (mtALDH) catalyzes the formation of 1,2-glyceryl dinitrate and nitrite from nitroglycerin (glyceryl trinitrate [GTN]) within mitochondria, leading to production of cGMP and vasorelaxation. However, whether this mechanism operates in the s...

journal_title：Circulation

authors： Zhang J,Chen Z,Cobb FR,Stamler JS

更新日期：2004-08-10 00:00:00

abstract：:Electrophysiologic effects of 50 mg iv ajmaline were evaluated in 10 patients with atrioventricular nodal reentrant paroxysmal supraventricular tachycardia (PSVT) utilizing the slow pathway for antegrade and the fast pathway for retrograde conduction. Ajmaline terminated the PSVT in all 10 patients in 17 to 165 sec (m...

journal_title：Circulation

authors： Sethi KK,Jaishankar S,Gupta MP

更新日期：1984-11-01 00:00:00

abstract：:There is now evidence that under resting conditions coronary vasodilator reserve exists even in the presence of myocardial ischemia. Therefore, we tested the hypothesis that a vasodilator reserve may exist during exercise so that during exercise-induced ischemia a reduction in coronary constrictor tone can be produced...

journal_title：Circulation

authors： Heusch G,Guth BD,Seitelberger R,Ross J Jr

更新日期：1987-02-01 00:00:00

abstract：BACKGROUND:Left ventricular wall motion (WM) abnormalities have recognized prognostic significance in patients with coronary or other heart diseases; however, whether abnormal WM predicts adverse events in adults without overt cardiovascular disease has not been assessed. Our objective was to determine whether echocard...

journal_title：Circulation

authors： Cicala S,de Simone G,Roman MJ,Best LG,Lee ET,Wang W,Welty TK,Galloway JM,Howard BV,Devereux RB

更新日期：2007-07-10 00:00:00

abstract：BACKGROUND:Abnormal vascular reactivity represents a fundamental disturbance in vascular biology with the development of atherosclerosis. Because endothelial vasodilator function plays a pivotal role in controlling vasomotor tone, we hypothesized that atherosclerotic wall thickening might directly interfere with defici...

journal_title：Circulation

authors： Zeiher AM,Schächlinger V,Hohnloser SH,Saurbier B,Just H

更新日期：1994-06-01 00:00:00

abstract：BACKGROUND:Hypertension decreases myocardial perfusion capacity in adults for several reasons, including insufficient coronary angiogenesis with left ventricular (LV) hypertrophy, arteriolar hypertrophy, and altered vasomotion. Heparin influences growth factors that promote angiogenesis and vasodilation and inhibit art...

journal_title：Circulation

authors： Flanagan MF,Aoyagi T,Arnold LW,Maute C,Fujii AM,Currier J,Bergau D,Warren HB,Rakusan K

更新日期：1999-08-31 00:00:00

abstract：BACKGROUND:Rel/NF-kappaB, an oxidative stress-responsive transcription factor, participates transiently in the control of gene expression. The cellular mechanisms that mediate NF-kappaB activation during ischemia (and during reperfusion in the course of treating ischemia) are not known. METHODS AND RESULTS:To investig...

journal_title：Circulation

authors： Canty TG Jr,Boyle EM Jr,Farr A,Morgan EN,Verrier ED,Pohlman TH

更新日期：1999-11-09 00:00:00

abstract：:Six cases of classical dissecting aneurysm of the aorta complicating aortic valvular disease in which aortic stenosis was dominant are described. In three of the cases the aortic complication occurred after the natural aortic valve had been replaced by a prosthetic valve. The longest postoperative period was four mont...

journal_title：Circulation

authors： Fukuda T,Tadavarthy SM,Edwards JE

更新日期：1976-01-01 00:00:00

abstract：BACKGROUND:Classically, intrinsic coagulation proteins are thought to have a minor role in hemostasis. Recently, these proteins, especially FXII, were implicated as possible key players in the pathogenesis of arterial thrombosis. This study aims to determine the risks of arterial thrombosis conferred by increased activ...

journal_title：Circulation

authors： Siegerink B,Govers-Riemslag JW,Rosendaal FR,Ten Cate H,Algra A

更新日期：2010-11-02 00:00:00