Pulmonary artery index. A nonpredictor of operative survival in patients undergoing modified Fontan repair.

abstract：BACKGROUND:Increased common carotid artery intima-media thickness (CCA-IMT) is a marker of early atherosclerosis. Low-grade inflammation is associated with the pathogenesis of atherosclerosis. Low-grade inflammation and increased CCA-IMT are observed in end-stage renal disease (ESRD). Oxidative stress is involved in ur...

journal_title：Circulation

authors： Drüeke T,Witko-Sarsat V,Massy Z,Descamps-Latscha B,Guerin AP,Marchais SJ,Gausson V,London GM

更新日期：2002-10-22 00:00:00

abstract：BACKGROUND:Experimental studies suggest that arterial injury and inflammation lead to increased neointimal growth after stenting. Despite the increased use of coronary stents in humans, there are only limited pathological data on the morphological features of in-stent restenosis. METHODS AND RESULTS:Detailed histology...

journal_title：Circulation

authors： Farb A,Weber DK,Kolodgie FD,Burke AP,Virmani R

更新日期：2002-06-25 00:00:00

abstract：:We have recently demonstrated that exercise training can induce important hemodynamic and metabolic adaptations in patients with chronic heart failure due to severe left ventricular dysfunction. This study examines the accompanying changes in submaximal exercise performance and the ventilatory response to exercise in ...

journal_title：Circulation

authors： Sullivan MJ,Higginbotham MB,Cobb FR

更新日期：1989-02-01 00:00:00

abstract：BACKGROUND:In the Myocardial Infarction, Triage, and Intervention (MITI) registry of acute myocardial infarction, 441 (12%) of 3750 patients had direct angioplasty as initial treatment. Approximately half (233) were performed in hospitals with no on-site surgery. METHODS AND RESULTS:Procedure success rates, use of eme...

journal_title：Circulation

authors： Weaver WD,Litwin PE,Martin JS

更新日期：1993-11-01 00:00:00

abstract：BACKGROUND:Adenosine is believed to be cardioprotective; however, it has not been elucidated whether the plasma adenosine level is increased in chronic heart failure. METHODS AND RESULTS:Seventy-one patients attending a specialized heart failure clinic during a 6-month period were grouped according to the cause of chr...

journal_title：Circulation

authors： Funaya H,Kitakaze M,Node K,Minamino T,Komamura K,Hori M

更新日期：1997-03-18 00:00:00

abstract：BACKGROUND:Short-term (<30 day) mortality after Q-wave myocardial infarction (MI) has declined over the decades, but it is unclear if rates of long-term sequelae after Q-wave MI have improved. METHODS AND RESULTS:In 546 Framingham Heart Study subjects (388 men with a mean age of 60 years; 158 women with a mean age of ...

journal_title：Circulation

authors： Guidry UC,Evans JC,Larson MG,Wilson PW,Murabito JM,Levy D

更新日期：1999-11-16 00:00:00

abstract：:Between 1964 and 1971, 49 patients were discharged from hospital following atrial baffle repair for transposition of the great arteries. Electrocardiograms of 47 of these patients were available for review seven months to eight and a half years (average 31 months) after operation. Of the 46 patients in sinus rhythm pr...

journal_title：Circulation

authors： Clarkson PM,Barratt-Boyles BG,Neutze JM

更新日期：1976-03-01 00:00:00

abstract：BACKGROUND:Factors predicting the occurrence of premature coronary artery disease (CAD) may not be quantitatively the same as those predicting CAD severity, particularly in women, in whom there have been few studies. METHODS AND RESULTS:To determine factors predictive of severity of CAD and of angina pectoris, we docu...

journal_title：Circulation

authors： Wang XL,Tam C,McCredie RM,Wilcken DE

更新日期：1994-05-01 00:00:00

abstract：:The predictive value of the myocardial scintigraphy with 99mTc-pyrophosphate was studied in 100 patients admitted to the coronary care unit with suspected acute myocardial infarction. None of the 21 patients with normal scintigrams had acute myocardial infraction by other criteria. Fifty-five percent of patients with ...

journal_title：Circulation

authors： Holman BL,Chisholm RJ,Braunwald E

更新日期：1978-02-01 00:00:00

abstract：BACKGROUND:Candidates for cardiac resynchronization therapy (CRT) receive either a biventricular pacemaker or a biventricular pacemaker with an implantable cardioverter-defibrillator (CRT-D). Optimal device selection remains challenging because the benefit of implantable cardioverter-defibrillator therapy may not be un...

journal_title：Circulation

authors： Lindvall C,Chatterjee NA,Chang Y,Chernack B,Jackson VA,Singh JP,Metlay JP

更新日期：2016-01-19 00:00:00

abstract：:Venous thromboembolism (VTE) is a major preventable disease that affects hospitalized inpatients. Risk stratification and prophylactic measures have good evidence supporting their use, but multiple reasons exist that prevent full adoption, compliance, and efficacy that may underlie the persistence of VTE over the past...

journal_title：Circulation

authors： Henke PK,Kahn SR,Pannucci CJ,Secemksy EA,Evans NS,Khorana AA,Creager MA,Pradhan AD,American Heart Association Advocacy Coordinating Committee.

更新日期：2020-06-16 00:00:00

abstract：:Inherited thoracic aortopathies denote a group of congenital conditions that predispose to disease of the thoracic aorta. Aortic wall weakness and abnormal aortic hemodynamic profiles predispose these patients to dilatation of the thoracic aorta, which is generally silent but can precipitate aortic dissection or ruptu...

journal_title：Circulation

authors： Fletcher AJ,Syed MBJ,Aitman TJ,Newby DE,Walker NL

更新日期：2020-05-12 00:00:00

abstract：:Power outputs that are below the anaerobic threshold (theta an) may be sustained for prolonged durations, whereas power outputs that are greater than theta an result in a significant reduction in the tolerable duration to fatigue. The theta an may therefore be considered to demarcate exercise intensity into moderate (...

journal_title：Circulation

authors： Whipp BJ

更新日期：1987-12-01 00:00:00

abstract：BACKGROUND:The contractile dysfunction observed in end-stage myocardial hypertrophy has at its base an abnormality in myocyte function. However, whether depressed contractile function is related to an alteration in contractile protein function is presently unknown. METHODS AND RESULTS:Contractile force, tension, and c...

journal_title：Circulation

authors： Fan D,Wannenburg T,de Tombe PP

更新日期：1997-05-06 00:00:00

abstract：BACKGROUND:Hyperhomocysteinemia is an independent risk factor for coronary heart disease (CHD). Dietary supplementation with B vitamins lowers plasma homocysteine by up to 30%. However, little is known about the potential beneficial effects of homocysteine lowering on vascular function in patients with CHD. METHODS AN...

journal_title：Circulation

authors： Chambers JC,Ueland PM,Obeid OA,Wrigley J,Refsum H,Kooner JS

更新日期：2000-11-14 00:00:00

abstract：BACKGROUND:Trends in cardiovascular mortality across Europe demonstrate significant geographical variation, and an understanding of these trends has a central role in global public health. METHODS AND RESULTS:Ischemic heart disease and cerebrovascular disease age-standardized death rates (as per International Classifi...

journal_title：Circulation

authors： Hartley A,Marshall DC,Salciccioli JD,Sikkel MB,Maruthappu M,Shalhoub J

更新日期：2016-05-17 00:00:00

abstract：BACKGROUND:The effects of cardiac transplantation on cognitive brain function are uncertain. METHODS AND RESULTS:We measured cognitive brain function and quality of life in out-of-hospital cardiac transplant candidates (n = 55; ejection fraction, 19.9%; age, 54.8 years [means]). After transplantation, the patients wer...

journal_title：Circulation

authors： Grimm M,Yeganehfar W,Laufer G,Madl C,Kramer L,Eisenhuber E,Simon P,Kupilik N,Schreiner W,Pacher R,Bunzel B,Wolner E,Grimm G

更新日期：1996-09-15 00:00:00

abstract：BACKGROUND:BET (bromodomain and extraterminal) epigenetic reader proteins, in particular BRD4 (bromodomain-containing protein 4), have emerged as potential therapeutic targets in a number of pathological conditions, including cancer and cardiovascular disease. Small-molecule BET protein inhibitors such as JQ1 have demo...

journal_title：Circulation

authors： Kim SY,Zhang X,Schiattarella GG,Altamirano F,Ramos TAR,French KM,Jiang N,Szweda PA,Evers BM,May HI,Luo X,Li H,Szweda LI,Maracaja-Coutinho V,Lavandero S,Gillette TG,Hill JA

更新日期：2020-12-15 00:00:00

abstract：BACKGROUND:Pathological cardiac hypertrophy induced by stresses such as aging and neurohumoral activation is an independent risk factor for heart failure and is considered a target for the treatment of heart failure. However, the mechanisms underlying pathological cardiac hypertrophy remain largely unknown. We aimed to...

journal_title：Circulation

authors： Tang X,Chen XF,Wang NY,Wang XM,Liang ST,Zheng W,Lu YB,Zhao X,Hao DL,Zhang ZQ,Zou MH,Liu DP,Chen HZ

更新日期：2017-11-21 00:00:00

abstract：BACKGROUND:Antiplatelet agents presently used in the secondary prevention of cardiovascular disease fail to prevent the majority of cases of recurrent stroke and systemic embolization. An evaluation of the efficacy of new agents is hampered by a lack of in vivo models in humans. Asymptomatic cerebral embolic signals (E...

journal_title：Circulation

authors： Molloy J,Martin JF,Baskerville PA,Fraser SC,Markus HS

更新日期：1998-10-06 00:00:00

abstract：BACKGROUND:Resting cardiac function does not necessarily affect exercise capacity. However, to determine whether it affects early dynamics of oxygen uptake (VO2) during exercise, we measured VO2 during a constant work rate and during incremental exercise testing in patients with a history of myocardial infarction. VO2 ...

journal_title：Circulation

authors： Koike A,Hiroe M,Adachi H,Yajima T,Yamauchi Y,Nogami A,Ito H,Miyahara Y,Korenaga M,Marumo F

更新日期：1994-11-01 00:00:00

abstract：BACKGROUND:Sudden cardiac death in children is a rare but devastating event. Experts have debated the merits of community-based screening programs using an ECG and targeting 2 potential high-risk groups: school-aged children initiating stimulant medications to treat attention-deficit/hyperactivity disorder and adolesce...

journal_title：Circulation

authors： Leslie LK,Cohen JT,Newburger JW,Alexander ME,Wong JB,Sherwin ED,Rodday AM,Parsons SK,Triedman JK

更新日期：2012-05-29 00:00:00

abstract：BACKGROUND:The antiarrhythmic drugs quinidine and verapamil are known to block alpha1-adrenoceptors (alpha1ARs). Alpha1ARs are a heterogeneous family of three subtypes (alpha1A, alpha1B, and alpha1D), and little is known about the effects of quinidine and verapamil on the different human alpha1AR subtypes. METHODS AND...

journal_title：Circulation

authors： Shibata K,Hirasawa A,Foglar R,Ogawa S,Tsujimoto G

更新日期：1998-04-07 00:00:00

abstract：BACKGROUND:Few data have evaluated physician adherence to cardiovascular disease (CVD) prevention guidelines according to physician specialty or patient characteristics, particularly gender. METHODS AND RESULTS:An online study of 500 randomly selected physicians (300 primary care physicians, 100 obstetricians/gynecolo...

journal_title：Circulation

authors： Mosca L,Linfante AH,Benjamin EJ,Berra K,Hayes SN,Walsh BW,Fabunmi RP,Kwan J,Mills T,Simpson SL

更新日期：2005-02-01 00:00:00

abstract：BACKGROUND:Postmortem-derived findings support the common beliefs that lipid-rich coronary plaques with a thin, fibrous cap are prone to rupture and that rupture and superimposed thrombosis are the primary mechanisms causing acute coronary syndromes. In vivo imaging with intracoronary techniques may disclose difference...

journal_title：Circulation

authors： de Feyter PJ,Ozaki Y,Baptista J,Escaned J,Di Mario C,de Jaegere PP,Serruys PW,Roelandt JR

更新日期：1995-09-15 00:00:00

abstract：:In a porcine preparation of cardiac arrest, we demonstrated that there is a marked paradox of venous acidemia and arterial alkalemia. This paradox is related to decreased clearance of CO2 from the lungs when pulmonary blood flow is critically reduced. Accordingly, increased venous PCO2 rather than metabolic acidosis d...

journal_title：Circulation

authors： Grundler W,Weil MH,Rackow EC

更新日期：1986-11-01 00:00:00

abstract：:Using a high-pressure liquid chromatographic assay, we measured serum amiodarone concentrations serially in 122 patients treated with amiodarone for 1.5-53 months (mean 9.3 months) for control of refractory symptomatic atrial or symptomatic and life-threatening ventricular tachyarrhythmias. The atrial tachyarrhythmias...

journal_title：Circulation

authors： Haffajee CI,Love JC,Canada AT,Lesko LJ,Asdourian G,Alpert JS

更新日期：1983-06-01 00:00:00

abstract：BACKGROUND:Catheter-based intrapericardial (IPC) delivery of therapeutic agents has recently been demonstrated. Paclitaxel is known to inhibit vascular smooth muscle cell proliferation. This study examined the effect of IPC instillation of paclitaxel on neointimal proliferation after balloon overstretch of porcine coro...

journal_title：Circulation

authors： Hou D,Rogers PI,Toleikis PM,Hunter W,March KL

更新日期：2000-09-26 00:00:00

abstract：:Thirteen patients with proven Q fever endocarditis and three additional patients with probable endocarditis are reviewed. The most helpful diagnostic test is the demonstration of a high complement fixing antibody titre to Phase 1 antigen of Coxiella burneti. The macroscopic pathology of the aortic valve is described a...

journal_title：Circulation

authors： Wilson HG,Neilson GH,Galea EG,Stafford G,O'Brien MF

更新日期：1976-04-01 00:00:00

abstract：:The clinical and pathologic features of 18 consecutive patients with peripartum cardiomyopathy at The Johns Hopkins Hospital were examined in an attempt to define the incidence of myocarditis and to determine its response to immunosuppressive agents. In addition to routine studies, patients were evaluated with echocar...

journal_title：Circulation

authors： Midei MG,DeMent SH,Feldman AM,Hutchins GM,Baughman KL

更新日期：1990-03-01 00:00:00