Prognostic value of plasma N-terminal pro-brain natriuretic peptide in patients with severe sepsis.

abstract：BACKGROUND:Because complement-mediated vascular injury participates in atherosclerosis and C-reactive protein (CRP) can activate the complement cascade, we sought to determine whether CRP affects the expression of the protective complement-inhibitory factors on the cell surface of endothelial cells (ECs). METHODS AND ...

journal_title：Circulation

authors： Li SH,Szmitko PE,Weisel RD,Wang CH,Fedak PW,Li RK,Mickle DA,Verma S

更新日期：2004-02-24 00:00:00

abstract：BACKGROUND:Airborne particulate matter has been linked to excess morbidity and mortality. Recent attention has focused on the effects of particulate exposure on cardiac autonomic control. Inhaled particulates may affect the autonomic nervous system either directly, by eliciting a sympathetic stress response, or indirec...

journal_title：Circulation

authors： Magari SR,Hauser R,Schwartz J,Williams PL,Smith TJ,Christiani DC

更新日期：2001-08-28 00:00:00

abstract：BACKGROUND:Macrophages in human atherosclerotic plaques produce a family of matrix metalloproteinases (MMPs), which may influence vascular remodeling and plaque disruption. Because oxidized LDL (ox-LDL) is implicated in many proatherogenic events, we hypothesized that ox-LDL would regulate expression of MMP-9 and tissu...

journal_title：Circulation

authors： Xu XP,Meisel SR,Ong JM,Kaul S,Cercek B,Rajavashisth TB,Sharifi B,Shah PK

更新日期：1999-03-02 00:00:00

abstract：BACKGROUND:Data from single-center studies suggest that echocardiographic parameters of mechanical dyssynchrony may improve patient selection for cardiac resynchronization therapy (CRT). In a prospective, multicenter setting, the Predictors of Response to CRT (PROSPECT) study tested the performance of these parameters ...

journal_title：Circulation

authors： Chung ES,Leon AR,Tavazzi L,Sun JP,Nihoyannopoulos P,Merlino J,Abraham WT,Ghio S,Leclercq C,Bax JJ,Yu CM,Gorcsan J 3rd,St John Sutton M,De Sutter J,Murillo J

更新日期：2008-05-20 00:00:00

abstract：BACKGROUND:Considering the controversial results published in the literature concerning associations between human leukocyte antigens (HLA) and rheumatic fever (RF), the purpose of the present study was to investigate by means of cosegregation analysis the participation of HLA genes in susceptibility to RF. METHODS AN...

journal_title：Circulation

authors： Gerbase-DeLima M,Scala LC,Temin J,Santos DV,Otto PA

更新日期：1994-01-01 00:00:00

abstract：BACKGROUND:Although acute pericarditis is a common complication of beta-thalassemia major, the prevalence and consequences of myocarditis in this disease have not been investigated. METHODS AND RESULTS:A prospective 5-year follow-up study was carried out in all patients with beta-thalassemia major in whom the diagnosi...

journal_title：Circulation

authors： Kremastinos DT,Tiniakos G,Theodorakis GN,Katritsis DG,Toutouzas PK

更新日期：1995-01-01 00:00:00

abstract：:Cross-sectional echocardiographic studies of the aortic arch and proximal descending aorta were performed in 18 patients with coarctation of the aorta and 20 normal subjects. In normals the aortic arch and proximal descending aorta appeared as an arcuate, echo-free structure curving across the plane of the scan. There...

journal_title：Circulation

authors： Weyman AE,Caldwell RL,Hurwitz RA,Girod DA,Dillon JC,Feigenbaum H,Green D

更新日期：1978-03-01 00:00:00

abstract：:Separate effects of perfusion hypothermia, potassium arrest, and procaine arrest were studied in 150 hearts using the isolated rat heart preparation. Aortic flow rate (AFR), coronary flow rate (CFR), and heart rate (HR) were measured before and after ischemic periods of 90 to 300 min. Prior to the ischemic period, the...

journal_title：Circulation

authors： Harlan BJ,Ross D,Macmanus Q,Knight R,Luber J,Starr A

更新日期：1978-09-01 00:00:00

abstract：BACKGROUND:The release of endothelium-derived relaxing factors has been shown experimentally to be of pivotal importance for the maintenance of coronary blood flow during increased demand. In humans with coronary atherosclerosis, endothelial vasodilator dysfunction is not confined only to epicardial conductance vessels...

journal_title：Circulation

authors： Zeiher AM,Krause T,Schächinger V,Minners J,Moser E

更新日期：1995-05-01 00:00:00

abstract：BACKGROUND:The extent and mechanism of the antithrombotic properties of fibrin-selective and non-fibrin-selective thrombolytic agents have not yet been established. METHODS AND RESULTS:The antithrombotic, thrombolytic, fibrinogenolytic, and pharmacokinetic properties of the following substances were determined in hams...

journal_title：Circulation

authors： Stassen JM,Nyström A,Hoylaerts M,Collen D

更新日期：1995-03-01 00:00:00

abstract：:Two-dimensional echocardiography can provide serial cross-sectional images of the left ventricular cavity. We examined whether such serial images from steady-state ejecting hearts would allow three-dimensional reconstruction and accurate volume estimation without major geometric assumptions. Cross-circulated, paced do...

journal_title：Circulation

authors： Eaton LW,Maughan WL,Shoukas AA,Weiss JL

更新日期：1979-08-01 00:00:00

abstract：:Twenty-four hour noninvasive ambulatory blood pressure and heart rate monitoring was performed on patients who underwent orthotopic cardiac transplantation, as part of the investigation of the de novo hypertension that developes in such patients. Patients with essential hypertension served as control subjects. The res...

journal_title：Circulation

authors： Reeves RA,Shapiro AP,Thompson ME,Johnsen AM

更新日期：1986-03-01 00:00:00

abstract：:Left main coronary artery disease (i.e., greater than or equal to 50% stenosis) was found in 1,477 of 20,137 patients in the Coronary Artery Surgery Study (CAS) registry. Of these patients, 53 (3.6%) were asymptomatic. Asymptomatic and symptomatic patients were similar in regard to 1) severity of left main coronary ar...

journal_title：Circulation

authors： Taylor HA,Deumite NJ,Chaitman BR,Davis KB,Killip T,Rogers WJ

更新日期：1989-06-01 00:00:00

abstract：:Between January 1, 1970, and December 31, 1974, 2981 patients underwent coronary arteriography. Twelve acute coronary dissections or embolizations occurred, an incidence of 0.4%. The incidences of acute occlusions for the Sones and Judkins techniques were 0.19% (4/2077 studies) and 0.88% (8/940), respectively. No inst...

journal_title：Circulation

authors： Guss SB,Zir LM,Garrison HB,Daggett WM,Block PC,Dinsmore RE

更新日期：1975-12-01 00:00:00

abstract：BACKGROUND:Many patients with implanted cardioverter defibrillators (ICDs) receive adjunctive antiarrhythmic drug therapy, most commonly amiodarone or sotalol. The effects of these drugs on defibrillation energy requirements have not been previously assessed in a randomized controlled trial. METHODS AND RESULTS:The Op...

journal_title：Circulation

authors： Hohnloser SH,Dorian P,Roberts R,Gent M,Israel CW,Fain E,Champagne J,Connolly SJ

更新日期：2006-07-11 00:00:00

abstract：BACKGROUND:Whether reperfusion can cause necrosis of previously viable myocytes (lethal reperfusion injury) remains controversial. Numerous studies examined the ability of various agents to prevent or limit reperfusion injury, but the results were contradictory. In a single-canine-heart model of ischemia-reperfusion, w...

journal_title：Circulation

authors： Zahger D,Yano J,Chaux A,Fishbein MC,Ganz W

更新日期：1995-06-15 00:00:00

abstract：:In this double-blind randomized study, 19 patients with acute transmural myocardial infarction were treated with methylprednisolone administered 4.4 +/- 0.7 hours (+/- SEM) after the onset of chest pain, and were compared with 21 patients who received placebo 4.5 +/- 0.4 hours after the start of clinical symptoms. The...

journal_title：Circulation

authors： Madias JE,Hood WB Jr

更新日期：1982-06-01 00:00:00

abstract：:A series of 252 isolated aortic homograft valves in 248 patients have been followed for 9 to 16.5 years (mean 10.8). The valves were sterilized in antibiotic solution and stored in a nutrient medium at 4 degrees C and were nonvital. There were 15 in-hospital deaths (6%) and a mortality of 2.7% in patients undergoing a...

journal_title：Circulation

authors： Barratt-Boyes BG,Roche AH,Subramanyan R,Pemberton JR,Whitlock RM

更新日期：1987-04-01 00:00:00

abstract：:The ameliorative effect of antiplatelet therapy on atherogenesis of vein grafts was assessed in autologous cephalic veins grafted into femoral arteries of 16 normolipemic and 11 hyperlipemic stump-tailed macaque monkeys. Before grafting, one half of each vein was distended at high pressure (700 mm Hg) and the other ha...

journal_title：Circulation

authors： Bonchek LI,Boerboom LE,Olinger GN,Pepper JR,Munns J,Hutchinson L,Kissebah AH

更新日期：1982-08-01 00:00:00

abstract：:Phasic blood flow recorded in five unobstructed dog aortocoronary bypass grafts to the left coronary artery was similar to that of normal coronary arteries, with a high diastolic-to-systolic flow ratio which averaged 2.7 +/- 0.4. With an average of 52 +/- 7% and 72 +/- 6% stenosis in the coronary artery distal to the ...

journal_title：Circulation

authors： Folts JD,Kahn DR,Bittar N,Rowe GG

更新日期：1975-08-01 00:00:00

abstract：BACKGROUND:It is recommended that comatose survivors of out-of-hospital cardiac arrest should be cooled to 32° to 34°C for 12 to 24 hours. However, the optimal level of cooling is unknown. The aim of this pilot study was to obtain initial data on the effect of different levels of hypothermia. We hypothesized that deepe...

journal_title：Circulation

authors： Lopez-de-Sa E,Rey JR,Armada E,Salinas P,Viana-Tejedor A,Espinosa-Garcia S,Martinez-Moreno M,Corral E,Lopez-Sendon J

更新日期：2012-12-11 00:00:00

abstract：BACKGROUND:Activated fibroblasts (myofibroblasts) play a critical role in cardiac fibrosis; however, their origin in the diseased heart remains unclear, warranting further investigation. Recent studies suggest the contribution of bone marrow fibroblast progenitor cells (BM-FPCs) in pressure overload-induced cardiac fib...

journal_title：Circulation

authors： Verma SK,Garikipati VNS,Krishnamurthy P,Schumacher SM,Grisanti LA,Cimini M,Cheng Z,Khan M,Yue Y,Benedict C,Truongcao MM,Rabinowitz JE,Goukassian DA,Tilley D,Koch WJ,Kishore R

更新日期：2017-09-05 00:00:00

abstract：BACKGROUND:Cyclooxygenase (COX)-2 contributes to vascular smooth muscle cell (VSMC) proliferation induced by tumor necrosis factor (TNF) and angiotensin II. The present study demonstrates, however, that depending on prevailing conditions, COX-2-derived prostanoids may also inhibit VSMC proliferation. METHODS AND RESUL...

journal_title：Circulation

authors： Haider A,Lee I,Grabarek J,Darzynkiewicz Z,Ferreri NR

更新日期：2003-08-26 00:00:00

abstract：BACKGROUND:The reason for the delay in onset of the electrophysiological effects and antiarrhythmic efficacy of amiodarone is not clear. The relation between the development of the electrophysiological effects of amiodarone and its myocardial concentration is unknown. We therefore examined the time course of developmen...

journal_title：Circulation

authors： Nanas JN,Mason JW

更新日期：1995-01-15 00:00:00

abstract：BACKGROUND:The introduction of limited approaches to the heart and the avoidance of cardiopulmonary bypass (CPB) aim to reduce the invasiveness of CABG by decreasing the systemic release of inflammatory cytokines, such as tumor necrosis factor (TNF)-alpha, interleukin (IL)-6, and IL-8, as well as the anti-inflammatory ...

journal_title：Circulation

authors： Diegeler A,Doll N,Rauch T,Haberer D,Walther T,Falk V,Gummert J,Autschbach R,Mohr FW

更新日期：2000-11-07 00:00:00

abstract：BACKGROUND:Coronary perfusion pressure has been shown to be a significant determinant of return of spontaneous circulation from cardiac arrest during asystole and electromechanical dissociation. The addition of interposed abdominal compression to otherwise standard cardiopulmonary resuscitation (CPR) increases coronary...

journal_title：Circulation

authors： Sack JB,Kesselbrenner MB,Jarrad A

更新日期：1992-12-01 00:00:00

abstract：BACKGROUND:In patients with acute coronary syndrome (ACS), percutaneous coronary intervention (PCI) may cause thrombus dislodgment followed by reduced flow and impaired microcirculatory function. We prospectively compared conventional PCI to a strategy of additional pretreatment using the X-sizer thrombectomy system. ...

journal_title：Circulation

authors： Beran G,Lang I,Schreiber W,Denk S,Stefenelli T,Syeda B,Maurer G,Glogar D,Siostrzonek P

更新日期：2002-05-21 00:00:00

abstract：BACKGROUND:The fatty acid composition of the phospholipids in sarcolemma may significantly influence cell membrane functions. We evaluated the effects of dietary fat on the pharmacodynamics of the antiarrhythmic drug propafenone in isolated, perfused rabbit hearts. METHODS AND RESULTS:Three groups of weanling rabbits ...

journal_title：Circulation

authors： Gillis AM,Keashly R,Watson PA,Mathison HJ,Parsons HG

更新日期：1992-04-01 00:00:00

abstract：BACKGROUND:Heart failure (HF) with preserved ejection fraction (HFpEF) is a heterogeneous syndrome. Phenotyping patients into pathophysiologically homogeneous groups may enable better targeting of treatment. Obesity is common in HFpEF and has many cardiovascular effects, suggesting that it may be a viable candidate for...

journal_title：Circulation

authors： Obokata M,Reddy YNV,Pislaru SV,Melenovsky V,Borlaug BA

更新日期：2017-07-04 00:00:00

abstract：BACKGROUND:Current knowledge of prevalence, incidence, and survival in thoracic aortic diseases (aneurysm and dissection) is based on small studies from a dated era of treatment and diagnostic procedures. The objective of the present study was to reappraise epidemiology and long-term outcomes in subjects with thoracic ...

journal_title：Circulation

authors： Olsson C,Thelin S,Ståhle E,Ekbom A,Granath F

更新日期：2006-12-12 00:00:00