Abstract:
:From January 1968 to June 1975 tricuspid regurgitation was encountered in 238 patients of a total of 1074 patients undergoing operations on the mitral valve. During this time tricuspid annuloplasty (TA) was performed in 137 patients and the tricuspid valve was replaced (TVR) in 101 patients. Comparison of hospital mortality of 15% (20 of 137) for TA as against 40% (40 or 101) for TVR suggests the superiority of repair over replacement. A new technique for repair makes this operation even more attractive. It satisfies the dual objectives of producing competency but not obstruction by creating a measured orifice. As experience with TA was gained, the incidence of valve replacement dropped from 69% (22 of 32) in the first 2 years of the study to 16% (11 of 70) for the last 2 years.
journal_name
Circulationjournal_title
Circulationauthors
Reed GE,Boyd AD,Spencer FC,Engelman RM,Isom OW,Cunningham JN Jrsubject
Has Abstractpub_date
1976-12-01 00:00:00pages
III96-8issue
6 Suppleissn
0009-7322issn
1524-4539journal_volume
54pub_type
杂志文章相关文献
CIRCULATION文献大全abstract:BACKGROUND:High blood pressure (BP) is a known risk factor for mobility and cognitive impairment in older adults. This study tested the association of cumulative BP exposure from young adulthood to midlife with gait and cognitive function in midlife. Furthermore, we tested whether these associations were modified by ce...
journal_title:Circulation
pub_type: 杂志文章,多中心研究
doi:10.1161/CIRCULATIONAHA.119.042502
更新日期:2020-03-03 00:00:00
abstract:BACKGROUND:approximately half of patients with heart failure die suddenly as a result of ventricular arrhythmias. Although abnormal Ca(2+) release from the sarcoplasmic reticulum through ryanodine receptors (RyR2) has been linked to arrhythmogenesis, the molecular mechanisms triggering release of arrhythmogenic Ca(2+) ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.110.982298
更新日期:2010-12-21 00:00:00
abstract:BACKGROUND:Microvascular dysfunction posttreatment of stroke with recombinant human tissue-type plasminogen activator (rht-PA) constrains the therapeutic window to 3 hours. Statins (3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors) promote vascular thrombolysis and reduce the inflammation response. We therefo...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.104.516757
更新日期:2005-11-29 00:00:00
abstract:BACKGROUND:Thioredoxin 2 (Trx2) is a key mitochondrial protein that regulates cellular redox and survival by suppressing mitochondrial reactive oxygen species generation and by inhibiting apoptosis stress kinase-1 (ASK1)-dependent apoptotic signaling. To date, the role of the mitochondrial Trx2 system in heart failure ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.114.012725
更新日期:2015-03-24 00:00:00
abstract::Atherosclerotic cardiovascular disease results in >19 million deaths annually, and coronary heart disease accounts for the majority of this toll. Despite major advances in treatment of coronary heart disease patients, a large number of victims of the disease who are apparently healthy die suddenly without prior sympto...
journal_title:Circulation
pub_type: 共识发展会议,杂志文章,评审
doi:10.1161/01.CIR.0000087481.55887.C9
更新日期:2003-10-14 00:00:00
abstract::This study was undertaken to assess the ability of proton magnetic resonance imaging (MRI) to detect myocardial ischemia shortly after coronary artery occlusion. Fifteen dogs were studied before and serially for up to 6 hr after anterior descending or circumflex coronary artery ligation in vivo by gated MRI with a 0.1...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.71.3.587
更新日期:1985-03-01 00:00:00
abstract::In three newborn infants with infradiaphragmatic total anomalous pulmonary venous connection, the common pulmonary vein was visualized with two-dimensional echocardiography and validated with saline contrast injections. The transducer was placed in the subcostal region in a sagittal body plane so as to image the desce...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.66.5.1129
更新日期:1982-11-01 00:00:00
abstract::In a group of 39 patients who received fibrinolytic therapy for acute myocardial infarction, serum crosslinked fibrin degradation products (XLDP) were quantitated by an enzyme-linked immunosorbent assay (ELISA) using an antibody reactive with a site near the gamma gamma crosslink of fibrin, and characterized by a gel ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.74.5.1027
更新日期:1986-11-01 00:00:00
abstract:BACKGROUND:Conversion of chronic atrial fibrillation (AF) is associated with atrial stunning, but the short-term effect of a brief episode of AF on left atrial appendage (LAA) emptying velocity is unknown. The purpose of this study was to determine whether a short episode of AF affects left atrial function and whether ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.99.23.3024
更新日期:1999-06-15 00:00:00
abstract:BACKGROUND:Consensus guidelines and hospital quality-of-care programs recommend that ST-elevation myocardial infarction patients achieve a door-to-balloon time of < or = 90 minutes. However, there are limited prospective data on specific measures to significantly reduce door-to-balloon time. METHODS AND RESULTS:We pro...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.106.677401
更新日期:2007-07-03 00:00:00
abstract:BACKGROUND:Increased plasma levels of atrial natriuretic peptide (ANP) and brain natriuretic peptide (BNP) have been identified as predictors of cardiac dysfunction and prognosis in congestive heart failure and ischemic heart disease. In severe sepsis patients, however, no information is available yet about the prognos...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.104.472050
更新日期:2005-07-26 00:00:00
abstract::Patients with lower-extremity peripheral artery disease (PAD) have greater functional impairment, faster functional decline, increased rates of mobility loss, and poorer quality of life than people without PAD. Supervised exercise therapy (SET) improves walking ability, overall functional status, and health-related qu...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIR.0000000000000727
更新日期:2019-09-24 00:00:00
abstract::These types of studies lay the foundation for understanding the human apolipoproteins at the genetic level. In addition, through a few specific examples, we have already shown evidence at the DNA level that lesions in apolipoprotein genes can play a role in human atherosclerosis. This work is in its infancy, but we ho...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.69.6.1190
更新日期:1984-06-01 00:00:00
abstract:BACKGROUND:Fibrinogen binding to the active conformation of the alpha(IIb)beta(3) integrin receptor (glycoprotein IIb/IIIa) and cytoskeletal reorganization are important events in platelet function. Tyrosine phosphorylation of platelet proteins plays an essential role in platelet signal transduction pathways. We studie...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.102.16.1924
更新日期:2000-10-17 00:00:00
abstract:BACKGROUND:Unlike the Western world, valvular disease ranks among the major cardiovascular afflictions in Africa. Acute rheumatic fever and chronic rheumatic valvular disease in their most virulent form are still commonly encountered and impose a huge burden on limited healthcare resources. METHODS AND RESULTS:We perf...
journal_title:Circulation
pub_type: 杂志文章,评审
doi:10.1161/CIRCULATIONAHA.105.539775
更新日期:2005-12-06 00:00:00
abstract:BACKGROUND:Recent failures of drugs that raised high-density lipoprotein (HDL) cholesterol levels to reduce cardiovascular events in clinical trials have led to increased interest in alternative indices of HDL quality, such as cholesterol efflux capacity, and HDL quantity, such as HDL particle number. However, no studi...
journal_title:Circulation
pub_type: 杂志文章,随机对照试验
doi:10.1161/CIRCULATIONAHA.116.025678
更新日期:2017-06-20 00:00:00
abstract:BACKGROUND:The mechanisms responsible for the transformation of stable angina to unstable angina, a major cause of morbidity and mortality, are commonly believed to be plaque rupture and thrombosis. We determined whether additional mechanisms are operative by analyzing the histopathology and immuno-histopathology of co...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.88.6.2493
更新日期:1993-12-01 00:00:00
abstract:BACKGROUND:Although autonomic imbalance is known to be characteristics of patients with clinically overt symptomatic congestive heart failure, it is currently unknown whether this autonomic response arises early in the course of left ventricular dysfunction or is restricted to the later stages of circulatory failure. ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.92.3.555
更新日期:1995-08-01 00:00:00
abstract:BACKGROUND:Candidates for cardiac resynchronization therapy (CRT) receive either a biventricular pacemaker or a biventricular pacemaker with an implantable cardioverter-defibrillator (CRT-D). Optimal device selection remains challenging because the benefit of implantable cardioverter-defibrillator therapy may not be un...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.115.018830
更新日期:2016-01-19 00:00:00
abstract:BACKGROUND:Coronary heart disease (CHD) is the leading cause of morbidity and mortality in persons with type 2 diabetes mellitus (T2DM). Electron-beam computed tomography (EBCT) detects coronary artery calcium (CAC), a marker of atherosclerotic plaque. Few studies have described EBCT-defined CHD among ethnic minorities...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000146377.15057.CC
更新日期:2004-11-02 00:00:00
abstract::Organ donor scarcity has resulted in an increasing number of long-distance cardiac allograft procurements. The effect on short-term (90-day) survival and cardiac function was assessed in a consecutive series of 167 heart transplants performed between April 1981 and July 1988. During that time, total allograft ischemic...
journal_title:Circulation
pub_type: 杂志文章
doi:
更新日期:1989-11-01 00:00:00
abstract:BACKGROUND:The electrocardiographic short QT-interval syndrome forms a distinct clinical entity presenting with a high rate of sudden death and exceptionally short QT intervals. The disorder has recently been linked to gain-of-function mutation in KCNH2. The present study demonstrates that this disorder is genetically ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000130409.72142.FE
更新日期:2004-05-25 00:00:00
abstract:BACKGROUND:Cardiac tissue engineering offers the prospect of a novel treatment for acquired or congenital heart defects. We have created vascularized pieces of beating cardiac muscle in the rat that are as thick as the adult rat right ventricle wall. METHOD AND RESULTS:Neonatal rat cardiomyocytes in Matrigel were impl...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/CIRCULATIONAHA.106.657379
更新日期:2007-01-23 00:00:00
abstract:BACKGROUND:Considering the controversial results published in the literature concerning associations between human leukocyte antigens (HLA) and rheumatic fever (RF), the purpose of the present study was to investigate by means of cosegregation analysis the participation of HLA genes in susceptibility to RF. METHODS AN...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.89.1.138
更新日期:1994-01-01 00:00:00
abstract:BACKGROUND:The excess risk of atherosclerosis among patients with non-insulin dependent diabetes mellitus (NIDDM) is well documented. However, the presence of conventional risk factors cannot fully account for this excess risk, and the underlying mechanism remains to be elucidated. The present study prospectively evalu...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.92.7.1770
更新日期:1995-10-01 00:00:00
abstract::As part of two Department of Veterans Affairs Cooperative Trials, we obtained angiographic patency data for internal mammary artery (IMA) and saphenous vein grafts to the left anterior descending (LAD) coronary artery at 1 year after coronary artery bypass surgery. Patients received either aspirin 325 mg q.d., aspirin...
journal_title:Circulation
pub_type: 临床试验,杂志文章,随机对照试验
doi:
更新日期:1990-11-01 00:00:00
abstract::An enzyme histochemical study of the sinoatrial node, the coronary sinus, and the atrial muscle extending into the anterior mitral valve was performed on human hearts. Investigation of the activity and localization of the structurally bound enzymes was performed by conventional histochemical techniques. Determination ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.72.1.205
更新日期:1985-07-01 00:00:00
abstract:BACKGROUND:Heart failure treatment depends partly on the underlying cause of the disease. We evaluated cardiovascular magnetic resonance (CMR) for the problem of differentiating dilated cardiomyopathy (DCM) from left ventricular (LV) dysfunction caused by coronary artery disease (CAD). METHODS AND RESULTS:Late gadolin...
journal_title:Circulation
pub_type: 临床试验,杂志文章
doi:10.1161/01.CIR.0000078641.19365.4C
更新日期:2003-07-08 00:00:00
abstract:BACKGROUND:Resistin, a plasma protein, induces insulin resistance in rodents. Recent reports suggest that circulating levels of resistin are elevated in obese and insulin-resistant rodents and humans. Whereas rodent resistin is made in adipocytes, macrophages are a major source of human resistin. Given the convergence ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.CIR.0000155620.10387.43
更新日期:2005-02-22 00:00:00
abstract:BACKGROUND:Friedreich's ataxia (FA), the most common inherited ataxia, is associated frequently with cardiac hypertrophy, and death is often cardiac related. Recently, the disease has been associated with a mutation that consists of an unstable expansion of GAA repeats in the first intron of the gene encoding frataxin ...
journal_title:Circulation
pub_type: 杂志文章
doi:10.1161/01.cir.95.9.2247
更新日期:1997-05-06 00:00:00