Abstract:
:Studies investigating the strength and membership of regions within multiple functional networks primarily focus on either resting state or single cognitive tasks. The goals of the current study were to investigate whether task-related functional connectivity changes with task complexity, and whether this connectivity-complexity relationship is age-sensitive. We assessed seed-to-voxel functional connectivity for the default mode network (DMN) and two attentional networks [cingulo-opercular (CO), fronto-parietal (FP)] in three cognitive control tasks of increasing complexity (Single task, Dual task, and Memory Updating), across younger and older adults (N = 52; NYoung = 23; NOld = 29). The three tasks systematically varied in cognitive control demands due to differing maintenance, switching, and updating requirements. Functional connectivity for all networks, resulting from task > rest contrasts, increased with greater task complexity, irrespective of age and gray matter volume. Moreover, between-network connectivity for DMN, CO, and FP regions was greatest for working memory updating, the most complex task. Regarding age-related differences in accuracy, none were observed for Single or Dual tasks, but older adults had poorer accuracy in Memory Updating. More anterior frontal clusters of functional connectivity were observed for older, compared to younger, adults; these were limited to seeds of the two attentional networks. Importantly, increased connectivity in these additional frontal regions in older adults were non-compensatory, because they were associated with detrimental task performance, especially Memory Updating. For the Memory Updating > Rest, the younger > older contrast resulted in greater DMN seed connectivity to regions in the other two attentional networks, implicating increased reliance on between-network connectivity for the DMN seeds during complex cognitive tasks. Our results also implicate functional connectivity between attentional networks and the cerebellum during cognitive control. Reliability of multiple seeds in the seed-to-voxel connectivity is also discussed.
journal_name
Neuropsychologiajournal_title
Neuropsychologiaauthors
O'Connell MA,Basak Cdoi
10.1016/j.neuropsychologia.2018.04.013subject
Has Abstractpub_date
2018-06-01 00:00:00pages
50-64eissn
0028-3932issn
1873-3514pii
S0028-3932(18)30154-4journal_volume
114pub_type
杂志文章相关文献
NEUROPSYCHOLOGIA文献大全abstract::Amnesia leads to a deficit in recollection that leaves familiarity-based recognition relatively spared. Familiarity is thought to be based on the fluent processing of studied items compared to novel items. However, whether amnesic patients respond normally to direct manipulations of processing fluency is not yet known...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2013.12.008
更新日期:2014-02-01 00:00:00
abstract::We hypothesized that word-stem completion (WSC) priming and perceptual identification (PI) priming, two types of repetition priming, rely on different cognitive and neural mechanisms: WSC priming on a modification mechanism that influences lexical retrieval, and PI priming on plasticity in pre-lexical perceptual syste...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(97)00155-3
更新日期:1998-05-01 00:00:00
abstract::To test the idea that associated with stuttering is a cognitive difficulty related to the organization of sequences of responses, stutterers and fluent speakers were compared on a task that required the transcription to paper of rapidly presented letter sequences ranging in length from 3 to 10 letters. Compared to flu...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(87)90123-0
更新日期:1987-01-01 00:00:00
abstract::We investigated the ability of patients with frontal-lobe lesions to benefit from advance information in a simple reaction-time task. The task involved pressing a button in response to the appearance of a peripheral target (visual angle of 11.5 degrees). A cue, presented in the centre of the screen, preceded the targe...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(98)00018-9
更新日期:1998-12-01 00:00:00
abstract::Research of the neurobiological bases of learning and memory suggest that these processes are not unitary in nature, but rather that relatively independent neural systems appear to mediate different types of memory. Neurobiological studies, for instance, have identified separable cognitive or "declarative" and stimulu...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/s0028-3932(02)00157-4
更新日期:2003-01-01 00:00:00
abstract::Spatial neglect can be accompanied by a pusher syndrome (PS) which is characterized by a postural deviation towards the contralesional side. In this study, the representation of the body orientation in the horizontal plane was evaluated in neglect patients with and without PS. The participants had to align a luminous ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2008.11.008
更新日期:2009-02-01 00:00:00
abstract::Very few studies have investigated autobiographical memory in the frontal variant of frontotemporal dementia (fv-FTD). The aim of this study was therefore to unravel the mechanisms of autobiographical memory disruption in general and in the anterograde and retrograde components of amnesia in particular, in patients su...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2006.04.031
更新日期:2006-01-01 00:00:00
abstract::Memory systems research has typically described the different types of long-term memory in the brain as either declarative versus non-declarative or implicit versus explicit. These descriptions reflect the difference between declarative, conscious, and explicit memory that is dependent on the medial temporal lobe (MTL...
journal_title:Neuropsychologia
pub_type: 杂志文章,评审
doi:10.1016/j.neuropsychologia.2013.06.019
更新日期:2013-08-01 00:00:00
abstract::The visual perception of size in different regions of external space was studied in Parkinson's disease (PD). A group of patients with worse left-sided symptoms (LPD) was compared with a group with worse right-sided symptoms (RPD) and with a group of age-matched controls on judgements of the relative height or width o...
journal_title:Neuropsychologia
pub_type: 临床试验,杂志文章
doi:10.1016/s0028-3932(02)00285-3
更新日期:2003-01-01 00:00:00
abstract::We investigated the neural basis of newly learned words in Spanish as a mother tongue (L1) and English as a second language (L2). Participants acquired new names for real but unfamiliar concepts in both languages over the course of two days. On day 3, they completed a semantic categorization task during fMRI scanning....
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2020.107703
更新日期:2020-12-09 00:00:00
abstract::The human brain has evolved a multifaceted fear system, allowing threat detection to enable rapid adaptive responses crucial for survival. Although many cortical and subcortical brain areas are believed to be involved in the survival circuits detecting and responding to threat, the amygdala has reportedly a crucial ro...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2020.107698
更新日期:2020-11-27 00:00:00
abstract::Right hemisphere lesions are known to impair, in many cases, visual recognition and visuospatial orientation. We report here on the compensatory strategies used by a patient whose posterior part of the right hemisphere was either destroyed or visually deafferented. She presented a slight appreceptive agnosia, memory d...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(93)90039-3
更新日期:1993-02-01 00:00:00
abstract::We examined the effects of emotional stimuli on right and left hemisphere detection performance in a hemifield visual discrimination task. A group of 18 healthy subjects were asked to discriminate between upright and inverted triangles (target). Targets were randomly presented in the left or right visual hemifield (15...
journal_title:Neuropsychologia
pub_type: 临床试验,杂志文章
doi:10.1016/s0028-3932(00)00072-5
更新日期:2000-01-01 00:00:00
abstract::The ventral stream of language processing has been implicated in the spontaneous expression of memory-encoded and emotionally infused information. The present study investigated whether left hemispheric lesions in post-stroke right-handed aphasic patients may be selectively associated with specific language functions....
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2017.05.010
更新日期:2017-07-01 00:00:00
abstract::Familiar face recognition is remarkably invariant across huge image differences, yet little is understood concerning how image-invariant recognition is achieved. To investigate the neural correlates of invariance, we localized the core face-responsive regions and then compared the pattern of fMR-adaptation to differen...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2016.10.004
更新日期:2016-12-01 00:00:00
abstract::The objective of this study was to validate a line bisection judgement (LBJ) task for use in investigating the lateralized cerebral bases of spatial attention in a sample of 51 right-handed healthy participants. Using functional magnetic resonance imaging (fMRI), the participants performed a LBJ task that was compared...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2016.11.024
更新日期:2017-01-08 00:00:00
abstract::Repetitive transcranial magnetic stimulation (rTMS) is thought to modulate brain function through methods of electromagnetic induction. Over the last few decades, a large body of studies have investigated the clinical applications of rTMS in a variety of patient populations for a diverse range of symptoms from depress...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2020.107395
更新日期:2020-04-01 00:00:00
abstract::Greene et al. [12] suggest that Alzheimer's disease (AD) patients approach repeated trials in a learning test as if they are single unrelated trials. Previous research [7] indicates that AD patients do not have explicit memory for item repetition when asked at test how many times a word was presented, but they do show...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(99)00142-6
更新日期:2000-01-01 00:00:00
abstract::Forward models, generated from the efference copies of motor commands, are thought to monitor the accuracy of ongoing movement. By comparing predicted with actual afferent information, forward models also aid in the differentiation of self-produced movements from externally generated ones. Many have proposed that a co...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.06.023
更新日期:2011-08-01 00:00:00
abstract::Affect sharing and prosocial motivation are integral parts of empathy that are conceptually and mechanistically distinct. We used a neurodegenerative disease (NDG) lesion model to examine the neural correlates of these two aspects of real-world empathic responding. The study enrolled 275 participants, including 44 hea...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2017.02.010
更新日期:2018-07-31 00:00:00
abstract::Two dichotic listening tests, one a verbal consonant-vowel identification task, the other a musical chord recognition task, were administered to 32 women at two points during the menstrual cycle, menses (when oestrogen is low) and the midluteal phase (when oestrogen is high), in a counterbalanced repeated measures des...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(98)00022-0
更新日期:1998-09-01 00:00:00
abstract::A Famous Faces Test designed to assess face recognition, spontaneous naming, verbal identification of un-named faces, and cued naming using semantic and phonetic cues was administered to 22 patients with dementia of Alzheimer type (DAT) and 25 matched controls. The DAT patients were significantly impaired in all test ...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(93)90128-m
更新日期:1993-08-01 00:00:00
abstract::Dichotic listening (DL) studies indicate higher proficiency of the right cerebral hemisphere in processing the pitch of auditory events. Especially, acoustic stimuli of a rich harmonic structure such as square waves (complex tones) elicit a left ear advantage (LEA) under dichotic stimulus application. In order to inve...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/s0028-3932(01)00159-2
更新日期:2002-01-01 00:00:00
abstract::This study investigated whether people with severe traumatic brain injury (TBI) demonstrate a specific impairment on tasks requiring them to make inferences about others' mental states (theory of mind tasks). Participants with severe TBI were compared to a healthy group on verbal first-order and second-order theory of...
journal_title:Neuropsychologia
pub_type: 临床试验,杂志文章
doi:10.1016/j.neuropsychologia.2004.04.027
更新日期:2005-01-01 00:00:00
abstract::The effect of age on tactile rod bisection is explored in an attempt to fully understand lateralized biases that are not driven by prior experience or visual processing. In Experiment 1, a total of 549 healthy participants aged between 3 and 84 years of age, divided into eight age groups, used touch alone without visi...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2011.08.015
更新日期:2011-10-01 00:00:00
abstract::In statistics and machine learning, model accuracy is traded off with complexity, which can be viewed as the amount of information extracted from the data. Here, we discuss how cognitive costs can be expressed in terms of similar information costs, i.e. as a function of the amount of information required to update a p...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2018.09.013
更新日期:2019-02-04 00:00:00
abstract::Dissociation between the ability to recognize misoriented objects and to determine their orientation has been reported in a small number of patients, but the long-term course of this deficit has not been reported so far. Here, we describe the case of a 32-year-old female who had bilateral occipito-temporal damage caus...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2004.10.010
更新日期:2005-01-01 00:00:00
abstract::A patient with unilateral visual neglect indicated whether a dot was or was not present in a display. When present, the dot appeared equally often in the left and right visual fields. Although he typically denied having seen dots in his left visual field, he was able to make this judgment much more quickly than when n...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(94)90002-7
更新日期:1994-02-01 00:00:00
abstract::This study investigated if the neural mechanisms involved in processing distance (near and far) and frame of reference (egocentric and allocentric) can be dissociated. 36 participants completed a conjunction visual search task using either an egocentric (deciding if the target was to their left or right) or an allocen...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/j.neuropsychologia.2014.12.019
更新日期:2015-07-01 00:00:00
abstract::We report the case of an aphasic patient, KP, whose spontaneous speech and ability to communicate verbally were severely reduced. His comprehension of written words was preserved. Naming was relatively preserved for objects but impaired for actions. We designed experiments to investigate his verb processing and senten...
journal_title:Neuropsychologia
pub_type: 杂志文章
doi:10.1016/0028-3932(95)00166-2
更新日期:1996-08-01 00:00:00