[Binding activity of circulating HBsAg particles for polymerized human albumin in acute hepatitis B].

Abstract:

:The binding activity of circulating HBsAg particles to polymerized human serum albumin (pHSA) was determined by radioimmunoassay in 18 patients with acute hepatitis B at follow-up and compared with other hepatitis B virus (HBV) markers. All patients had serum HBsAg particles with binding sites for pHSA during the acute phase of disease. Elimination of HBsAg particles with pHSA receptors occurred within 1 to 8 weeks in uncomplicated courses and in one case with a protracted course of 16 weeks before total elimination of HBsAg. The pHSA-test became negative after elimination of HBsAg in most instances. Three patients developed chronic hepatitis with persistence of pHSA-binding HBsAg particles. Circulating HBcAg dissociated by chaotropic ions was detectable in the first week of observation in 4 of 15 patients who recovered and persisted in 3 cases with transition to chronic disease. The results show that acute hepatitis B is associated with circulating pHSA-binding HBsAg particles which can serve as a prognostic marker of the early phase of the disease.

journal_name

Z Gastroenterol

authors

Hopf U,Möller B,Muirhead B,Alexander M

subject

Has Abstract

pub_date

1985-11-01 00:00:00

pages

643-9

issue

11

eissn

0044-2771

issn

1439-7803

journal_volume

23

pub_type

杂志文章
  • [Early gastric cancer, results in a county hospital (author's transl)].

    abstract::In a nine-year period, 46 patients with early gastric cancer were diagnosed and operated at a county hospital. Fiberscopy of the stomach raised the percentage of early gastric cancer from 1% in a five year pre-endoscopic period to 11.9% with endoscopy. On an average, subjects with early gastric cancer were 8 years you...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Schmid E,Gehl H,Blaich E,Haag S,Lorentz H,Kovarik P,Rettenmayr K,Schwarzkopf H

    更新日期:1981-02-01 00:00:00

  • [Diagnosis of functional esophageal disorders in non-cardiac chest pain syndrome].

    abstract::The results of a cardiologic work-up in patients with retrosternal pain are negative in about 20-30% of cases. Overall one half of these patients exhibit an esophageal dysfunction. In order to diagnose esophageal dysfunction long-term pH-metry, transit scintigraphy and standard manometry are used as well as provocatio...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:

    authors: Adamek RJ,Wegener M,Wienbeck M

    更新日期:1993-12-01 00:00:00

  • Interrelation between ABH blood group 0, Lewis(B) blood group antigen, Helicobacter pylori infection, and occurrence of peptic ulcer.

    abstract:BACKGROUND:Helicobacter pylori is a human pathogen that causes chronic gastritis and peptic ulcers. Epidemiological studies demonstrated that individuals who are blood group 0 positive or represent non-secretors of their blood group antigens are more likely to develop peptic ulcers. The Lewis(b) blood group antigen has...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2002-30115

    authors: Keller R,Dinkel KC,Christl SU,Fischbach W

    更新日期:2002-05-01 00:00:00

  • Enhanced proliferative response to beta-endorphin of phytohemagglutinin-activated lymphocytes from patients with ulcerative colitis.

    abstract::We investigated the effect of a known T cell mitogen, phytohemagglutinin (PHA) and the neuropeptide beta-endorphin on the in vitro lymphocyte proliferative response in patients with ulcerative colitis and in health persons. We found that patients with ulcerative colitis show enhanced reactivity to PHA, when incubated ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Nikolopoulou V,Lafi T,Athanasiadou A,Zoumbos N

    更新日期:1991-06-01 00:00:00

  • [Recent developments in biopsy diagnosis of early and undefined liver tumors].

    abstract::Biopsy diagnosis of early and highly differentiated liver tumors is difficult and complex. Modern pathology has met this challenge by several different means; elaborate morphological algorithms and novel immunohistological markers support the differential diagnosis of highly differentiated HCC and a new, predictive mo...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0028-1109088

    authors: Longerich T,Schirmacher P

    更新日期:2009-01-01 00:00:00

  • [Two-stage esophageal resection with ischemic preconditioning of the gastric tube in decompensated dolichomegaesophagus and end-stage achalasia].

    abstract::Development of a megaesophagus with a sigmoid-shaped distal part in patients with achalasia--even in the course of successful myotomy with reduction of the resting pressure of the lower esophageal sphincter--is often the expression of an irreversible progression of the disease. Management of patients with end-stage ac...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1027374

    authors: Gockel I,Musholt TJ,Eckardt V,Mildenberger P,Müller H,Lang H

    更新日期:2008-11-01 00:00:00

  • Immunobiology and gene-based immunotherapy of hepatocellular carcinoma.

    abstract:PURPOSE:Hepatocellular carcinoma (HCC) is one of the major malignancies worldwide. For most patients with advanced or multifocal HCC treatment options are limited resulting in a poor prognosis. Several local ablation methods have been developed as minimally invasive strategies for HCC treatment. It is unclear, until no...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2003-44304

    authors: Geissler M,Mohr L,Ali MY,Grimm CF,Ritter M,Blum HE

    更新日期:2003-11-01 00:00:00

  • [Medicamentous modification of gastrointestinal motility and secretion].

    abstract::This article gives an overview on possible new pharmacological tools to modify gastrointestinal motility and/or secretion. The characterization of new subclasses of classical neurotransmitter receptors and of peptidergic receptors offer a new approach for the development of new therapeutic agents. Using molecular biol...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:

    authors: Allescher HD

    更新日期:1991-04-01 00:00:00

  • Assessment of afferent gut--brain function using cerebral evoked responses to esophageal stimulation.

    abstract::Increasing awareness is attributed to altered sensory perception in the pathogenesis of gastrointestinal disorders. Evoked potentials (EP), which represent the brain's electrical response to peripheral stimulation, have recently been used to investigate where and how (GI) afferent information is processed along the br...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:

    authors: Hollerbach S,Kamath MV,Lock G,Schölmerich J,Upton AR,Tougas G

    更新日期:1998-04-01 00:00:00

  • Circulating ICAM-1 (sCD54) and LFA-3 (sCD58) in chronic hepatitis B--a longitudinal study in patients treated with interferon-alpha.

    abstract::The intercellular adhesion molecule 1 (ICAM-1, CD54) and the lymphocyte associated antigen 3 (LFA-3, CD58) have been found in soluble form (sCD54 and sCD58) in human sera. Data concerning their role in chronic liver disease and their usefulness in disease monitoring are contradictory. We addressed the question whether...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Knolle PA,Eckardt AJ,Protzer-Knolle U,Schirmacher P,Dienes HP,Meyer zum Büschenfelde KH,Gerken G

    更新日期:1997-06-01 00:00:00

  • Assessment of disease activity in a registry of Crohn's disease patients in eastern Pennsylvania.

    abstract::The objectives of this report are to: 1) compare the Crohn's disease (CD) patient's assessment of their well-being to the physician's assessment of the patient's well-being, 2) use the existing Crohn's disease indices (CDI) in comparing the severity of CD with the patient's self assessment, and 3) compare the CDI with...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Reed JF 3rd,Faust LA,Rosen L

    更新日期:1991-08-01 00:00:00

  • [Liver cirrhosis and chronic hepatic porphyria].

    abstract::Chronic hepatic porphyrias (CHP) are associated with different degrees of liver damage. They range from minimal histological changes to cirrhosis and primary liver carcinomas. Forty patients with early stages of porphyrias were compared to 85 patients with clinically manifest porphyrias, Porphyria cutanea tarda. This ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Pätzold K,Hahn L,Lohmann J,Porst H

    更新日期:1993-02-01 00:00:00

  • Effect of ursodeoxycholic acid on the inflammatory activity of indomethacin-induced intestinal inflammation in rats.

    abstract::The beneficial effects of ursodeoxycholic acid (UDCA) in primary biliary cirrhosis are supposed to be mediated in part by immunological mechanisms. In this study, we have tested whether ursodeoxycholic acid also ameliorates intestinal inflammation induced by indomethacin in rats. Intestinal inflammation was induced in...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Kullmann F,Gross V,Rüschoff J,Arndt H,Benda W,Winkler von Mohrenfels A,Schölmerich J

    更新日期:1997-03-01 00:00:00

  • [Phospholipase A2--acute phase protein after liver surgery?].

    abstract:INTRODUCTION:The exact source of phospholipase A2 is unknown. In this context the liver is discussed because the secretion of phospholipase A2 could be initiated during an acute phase response. PATIENTS AND METHODS:Three groups of patients were prospectively established: A liver resection (n = 12); B control (n = 22; ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Gerhard F,Treusch H,Hofmann GE,Büssow M,Hanisch E

    更新日期:1997-04-01 00:00:00

  • Gastrointestinal stromal tumours in patients with other-type cancer: a mere coincidence or an etiological association? A study of 97 GIST cases.

    abstract::Gastrointestinal stromal tumours (GIST) occur mostly as sporadic solitary lesions involving the tubular GI tract and are only rarely associated with other benign or malignant neoplasms or occur as part of a multi-neoplastic disease as in the setting of Carney's triad and von Recklinghausen's disease. We analysed a tot...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2005-858378

    authors: Agaimy A,Wuensch PH

    更新日期:2005-09-01 00:00:00

  • Update on cholangiocarcinoma: potential impact of genomic studies on clinical management.

    abstract::The term cholangiocarcinoma (CCA) comprises neoplasms of the intrahepatic, perihilar, and distal bile duct. Five-year survival rates of patients with CCA are below 20 %, and no targeted therapy could prove a benefit in comparison to the standard treatment of cisplatinum and gemcitabine. In recent years, next generatio...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-0043-102581

    authors: Walter D,Hartmann S,Waidmann O

    更新日期:2017-06-01 00:00:00

  • [Pancreatic interventions: biopsy, drainage, necrosectomy--from the viewpoint of the radiologist].

    abstract::The following publication is an overview looking at diagnostic and therapeutic possibilities related to interventional procedures for diseases of the pancreas. We emphasize the description of the technique and show meaningful indications and limitations. ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2000-10302

    authors: Tomczak RJ,Görich J,Gabelmann A,Krämer S,Rilinger N,Brambs HJ

    更新日期:2000-11-01 00:00:00

  • The impact of capsule endoscopy on surgical results in patients with obscure gastrointestinal bleeding.

    abstract:BACKGROUND:Obscure gastrointestinal bleeding (OGIB) that cannot be established applying traditional endoscopic methods represents 5 % of all gastrointestinal bleedings. Earlier, in cases of recurrent, overt bleedings the surgeons had to perform a laparotomy "blind" without diagnosis. The aim of our retrospective study ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1027983

    authors: Kovács M,Pák P,Pák G,Oláh A,Rácz I

    更新日期:2009-05-01 00:00:00

  • Work satisfaction and burnout risk of gastroenterologists in Germany: results of a nationwide survey.

    abstract:BACKGROUND: More and more gastroenterologists are not satisfied with their working conditions and run the risk of developing burnout symptoms. Little is known about the job satisfaction and burnout risk among physicians working in endoscopy units in Germany. This study examines the risk of burnout and job satisfaction ...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/a-1176-2344

    authors: Adarkwah CC,Labenz J,Birkner B,Beilenhoff U,Hirsch O

    更新日期:2020-10-01 00:00:00

  • Non-operative management in a case of spontaneous splenic rupture in infectious mononucleosis.

    abstract::Spontaneous splenic rupture as a complication of infectious mononucleosis was diagnosed in a 19-year-old woman. Sonographic and MRI investigations revealed subcapsular hematoma of the spleen without overt rupture. The patient was managed conservatively. Somatostatin treatment was initiated in order to reduce splanchni...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Paar WD,Look MP,Robertz Vaupel GM,Kreft B,Hirner A,Sauerbruch T

    更新日期:1995-01-01 00:00:00

  • [Endothelial adrenal cyst mimicking cystic echinococcosis in a Turkish woman].

    abstract:BACKGROUND:Cystic liver lesions include hepatic echinococcosis as an important differential diagnosis, especially in patients from endemic countries. Serology might be false negative in a relevant percentage of the patients. Thus, modern clinical imaging techniques are the most important non-invasive means for making o...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2008-1027295

    authors: Stock K,Hann von Weyhern C,Holzapfel K,Clevert DA,Schmid RM,Lersch C

    更新日期:2008-10-01 00:00:00

  • Large-bowel obstruction as a late sequela of retrosternal diaphragmatic hernia.

    abstract::A 37-year-old man with a past history of a fall from height 16 years previously was admitted with acute abdomen. Investigations revealed intestinal obstruction caused by a diaphragmatic hernia. He had an incarcerated omentum and Richter's hernia of the transverse colon secondary to left diaphragmatic hernia leading to...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-0029-1245982

    authors: Kaptanoglu B,Yildiz M,Taş A,Köklü S,Pekcici R,Karakayali AS

    更新日期:2011-08-01 00:00:00

  • [Disseminated tuberculosis mimicking metastatic gastric cancer - a case report].

    abstract::Increasing numbers of active tuberculosis in Germany were recorded in the last years. Thus, also extrapulmonary manifestations of tuberculosis gain clinical significance as differential diagnoses, especially when a metastatic tumor disease is suspected. We report the case of a 77-year-old male patient who presented wi...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/a-1030-4781

    authors: Voit FM,Abdelhafez M,Rothe K,Slotta-Huspenina J,Gaa J,Schmid RM,Spinner CD

    更新日期:2019-12-01 00:00:00

  • [Portopulmonary hypertension].

    abstract::Patients with portal hypertension may develop pulmonary complications such as hepatopulmonary syndrome (HPS) or portopulmonary hypertension (PPHT). PPHT is defined as elevated pulmonary pressure, elevated pulmonary vascular resistance, a normal pulmonary capillary wedge pressure, and portal hypertension in the absence...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章,评审

    doi:10.1055/s-2005-857926

    authors: Halank M,Miehlke S,Kolditz M,Hoeffken G

    更新日期:2005-07-01 00:00:00

  • [Pharmacotherapy in patients with ulcerative colitis].

    abstract:BACKGROUND:Patients with ulcerative colitis experience various impairments. The pharmacological treatment of the disease comprises 5-aminosalicylic acid, corticosteroids as well as immunomodulatory and biological agents. Little self-reported data exist on the prescription of these drugs. METHODS:This cross-sectional s...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-0031-1273276

    authors: Scherer M,Hardt J,Blozik E,Preiss JC,Bokemeyer B,Hüppe A,Raspe H

    更新日期:2011-07-01 00:00:00

  • [APC resistance due to factor V Leiden mutation presenting as acute hemorrhagic jejunal infarction--case report].

    abstract::We report on a 43-year-old patient presenting to the emergency department with acute abdominal pain the source of which turned out to be acute hemorrhagic jejunal infarction due to portal and mesenteric vein occlusion with no apparent cause. In spite of a lacking history of hereditary thrombophilic risk factors, furth...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2007-963528

    authors: Garlipp B,Gerhardt U,Linke J,Arlt G

    更新日期:2008-02-01 00:00:00

  • [Cystic neoplasms of the pancreas: surgical therapy and chances for cure].

    abstract::Between 1986 and 1997 we treated 67 patients with 68 cystic tumors of the pancreas including 17 mucinous cystadenocarcinomas, four serous cystadenocarcinomas, 15 mucinous cystadenomas, 18 serous cystadenomas, ten intraductal papillary-mucinous tumors, three solid-pseudopapillary tumors, and one cystic neuroendocrine t...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Schmidt-Rohlfing B,Siech M,Mattfeldt T,Schoenberg MH,Beger HG

    更新日期:1998-11-01 00:00:00

  • [Gastrointestinal stromal tumours (GIST) of the jejunum in a patient with neurofibromatosis type 1 (von Recklingshausen's disease)].

    abstract:CASE REPORT:A 72-year-old female patient with known neurofibromatosis type 1 was admitted to the hospital with symptomatic anaemia and a history of melaena. Upper and lower endoscopy did not show any signs of bleeding. Ultrasound and computed tomography revealed an abdominal mass. The histological analysis of a US-guid...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:10.1055/s-2004-813587

    authors: Köppen S,Wejda B,Dormann A,Hoffmeister D,Stolte M,Huchzermeyer H

    更新日期:2004-10-01 00:00:00

  • [Therapy of bleeding mucosal erosion of the stomach with secretin].

    abstract::In a prospective study patients with bleeding from acute gastric mucosal lesions were treated by i.v. infusions of secretin. 67 patients received natural secretin (Karolinska-Institut Stockholm), 14 patients received synthetic secretin (Firma Hoechst Frankfurt). In 64 of the 67 patients (95%) who received natural secr...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Becker HD

    更新日期:1980-06-01 00:00:00

  • [Intragastric utilization of antacids following meals in relation to stomach emptying].

    abstract::Gastric acid secretion and gastric emptying rate was measured using double marker method and continuous titration of a liquid peptone test meal. Titration rate was significantly reduced by 30 ml of an aluminiumhydroxide- and magnesiumhydroxide containing antacid compound (Maalox). Acidity of gastric contents was reduc...

    journal_title:Zeitschrift fur Gastroenterologie

    pub_type: 杂志文章

    doi:

    authors: Lux G,Hartog C,Ruppin H,Lederer P,Schmitt W

    更新日期:1983-03-01 00:00:00