Abstract:
:We have characterised 997 hip fracture patients from a representative 45 Spanish hospitals, and followed them up prospectively for up to 4 months. Despite suboptimal surgical delays (average 59.1 hours), in-hospital mortality was lower than in Northern European cohorts. The secondary fracture prevention gap is unacceptably high at 85%. PURPOSE:To characterise inpatient care, complications, and 4-month mortality following a hip or proximal femur fracture in Spain. METHODS:Design: prospective cohort study. Consecutive sample of patients ≥ 50 years old admitted in a representative 45 hospitals for a hip or proximal femur fragility fracture, from June 2014 to June 2016 and followed up for 4 months post-fracture. Patient characteristics, site of fracture, in-patient care (including secondary fracture prevention) and complications, and 4-month mortality are described. RESULTS:A total of 997 subjects (765 women) of mean (standard deviation) age 83.6 (8.4) years were included. Previous history of fracture/s (36.9%) and falls (43%) were common, and 10-year FRAX-estimated major and hip fracture risks were 15.2% (9.0%) and 8.5% (7.6%) respectively. Inter-trochanteric (44.6%) and displaced intra-capsular (28.0%) were the most common fracture sites, and fixation with short intramedullary nail (38.6%) with spinal anaesthesia (75.5%) the most common procedures. Surgery and rehabilitation were initiated within a mean 59.1 (56.7) and 61.9 (55.1) hours respectively, and average length of stay was 11.5 (9.3) days. Antithrombotic and antibiotic prophylaxis were given to 99.8% and 98.2% respectively, whilst only 12.4% received secondary fracture prevention at discharge. Common complications included delirium (36.1 %) and kidney failure (14.1%), with in-hospital and 4-month mortality of 2.1% and 11% respectively. CONCLUSIONS:Despite suboptimal surgical delay, post-hip fracture mortality is low in Spanish hospitals. The secondary fracture prevention gap is unacceptably high at > 85%, in spite of virtually universal anti-thrombotic and antibiotic prophylaxis.
journal_name
Arch Osteoporosjournal_title
Archives of osteoporosisauthors
Prieto-Alhambra D,Reyes C,Sainz MS,González-Macías J,Delgado LG,Bouzón CA,Gañan SM,Miedes DM,Vaquero-Cervino E,Bardaji MFB,Herrando LE,Baztán FB,Ferrer BL,Perez-Coto I,Bueno GA,Mora-Fernandez J,Doñate TE,Blasco JM,Agudoi
10.1007/s11657-018-0515-8subject
Has Abstractpub_date
2018-09-14 00:00:00pages
96issue
1eissn
1862-3522issn
1862-3514pii
10.1007/s11657-018-0515-8journal_volume
13pub_type
杂志文章abstract:PURPOSE:Using data from the 2-year, randomized, double-dummy VERO trial, we examined the changes in 25-hydroxy-vitamin D (25[OH]D) concentrations over time, and whether the fracture risk reduction of teriparatide versus risedronate varies by baseline 25(OH)D sufficiency category. METHODS:Postmenopausal women with esta...
journal_title:Archives of osteoporosis
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11657-019-0561-x
更新日期:2019-01-18 00:00:00
abstract:PURPOSE:Management of fracture nonunion is challenging as another surgical intervention for the patient is often a necessity, which has a huge impact on both quality of life and economic burden of the patient. Thus, a less aggressive and better accepted treatment for nonunion is required. METHODS:We gave teriparatide ...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-017-0311-x
更新日期:2017-12-01 00:00:00
abstract::This study aims to determine the awareness of osteoporosis and factors that determine awareness of osteoporosis. Results showed that osteoporosis awareness was associated with age (p = 0.006) and occupation (p < 0.001) but not gender, marital status, and level of education. There is therefore need for educational inte...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-017-0342-3
更新日期:2017-12-01 00:00:00
abstract::In the past 10 years after implementation, the orthogeriatric treatment model led in general to consistent outcomes for 1555 older adults in terms of most of the complications and mortality. Surgery was more often delayed to 24-48 h after arrival at the hospital, while the length of hospital stay shortened. INTRODUCT...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0550-5
更新日期:2018-11-19 00:00:00
abstract:OBJECTIVE:A summary of recommendations is given within the Gulf Cooperation Council (GCC) setting on the assessment and management of vitamin D deficiency in the region. METHODS:An assembly of 11 regional experts gathered to formulate an all-inclusive approach to vitamin D deficiency within GCC. RESULTS AND CONCLUSIO...
journal_title:Archives of osteoporosis
pub_type: 共识发展会议,杂志文章
doi:10.1007/s11657-020-0709-8
更新日期:2020-03-02 00:00:00
abstract:UNLABELLED:This study aimed to investigate women's perspectives and experiences with screening for osteoporosis. Focus groups and individual interviews were conducted. Three main themes emerged: knowledge about osteoporosis, psychological aspects of screening, and moral duty. Generally, screening was accepted due to li...
journal_title:Archives of osteoporosis
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11657-014-0192-1
更新日期:2014-01-01 00:00:00
abstract::Previous studies have shown that improving vitamin D status among the elderly may lead to an improvement in muscle mass and muscle strength. In our study, vitamin D supplementation showed significant improvements in vitamin D concentrations as well as appendicular muscle mass in pre-sarcopenic older Lebanese people. H...
journal_title:Archives of osteoporosis
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11657-018-0553-2
更新日期:2018-12-19 00:00:00
abstract::In pre-pubertal girls, nutrient intakes and non-aquatic organized activity were evaluated as factors in vertebral body bone mass, structure, and strength. Activity, vitamin B12, and dietary fiber predicted bone outcomes most consistently. Exercise and vitamin B12 appear beneficial, whereas high fiber intake appears to...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-017-0312-9
更新日期:2017-12-01 00:00:00
abstract::In November 2008, the "2nd Summit on Osteoporosis-Central and Eastern Europe (CEE)" was held in Warsaw, Poland. Discussions at this meeting focused on the identification and discussion of diagnostic, preventive, and therapeutic measures used in CEE. Evaluated information was used to identify issues regarding diagnosis...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-009-0028-6
更新日期:2009-12-01 00:00:00
abstract::While adherence to osteoporosis treatment is low, patients' preference for osteoporosis treatment is unknown in Chinese patients. Chinese patients are willing to receive treatments with higher clinical efficacy and lower out-of-pocket cost. In addition, annual intravenous infusion and 6-month subcutaneous injection ar...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0624-z
更新日期:2019-07-31 00:00:00
abstract::This cross-sectional study among members of public showed that people generally had good knowledge and awareness about vitamin D. However, inconsistencies between awareness and attitudes were observed. Our findings reinforce the need of educating people to improve attitude and practices toward vitamin D consumption. ...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0671-5
更新日期:2019-11-22 00:00:00
abstract::We examined the effect of cumulative exposure to high doses of oral glucocorticoids on fracture risk. Compared to short-course users (daily dose ≥ 15 mg + cumulative < 1 g), heavy users (daily dose ≥ 15 mg + cumulative dose ≥ 1 g) had the highest risk of fracture. These patients should be monitored for fracture manage...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0424-x
更新日期:2018-03-18 00:00:00
abstract::Older men who participated in a sporting activity were less likely to sustain any fracture or major osteoporotic fracture over a 6-year follow-up period. PURPOSE:Regular weight-bearing physical activity can reduce fracture risk through an increase in bone strength, as well as reducing falls risk by improving muscle s...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0459-z
更新日期:2018-04-19 00:00:00
abstract::This study aimed to investigate the correlation between bone mineral density (BMD) with hemoglobin and ferritin levels in Palestinian patients suffering from various types of hemoglobinopathies. The study revealed the thresholds of hemoglobin and ferritin to protect against low BMD in these patients. PURPOSE:Iron ove...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00853-x
更新日期:2020-11-13 00:00:00
abstract::MrOS MsOS (Hong Kong) studies year 14 follow-up shows for subjects without baseline osteoporotic vertebral deformity, women's incident vertebral fracture (VF) rate was twice that of men. For subjects with vertebral deformity of baseline ≥ 20% height loss, counting subject, women's incident VF rate was three times high...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00845-x
更新日期:2020-11-07 00:00:00
abstract:UNLABELLED:Serum concentrations of osteocalcin (OC) decrease and those of C-terminal telopeptide of type 1 collagen (CTX) increase during weight loss in adolescent girls with eating disorders (ED). The impact of weight loss on bone metabolism markers is greatest in premenarcheal girls. INTRODUCTION:Adolescents with ED...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-012-0090-3
更新日期:2012-01-01 00:00:00
abstract:UNLABELLED:Although depression has been associated to worst bone physical properties in adulthood, this study showed that depressive symptoms were not significantly associated to bone mineral density measured at the forearm during adolescence. PURPOSE:Depressive conditions have been related to the reduction of bone mi...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-014-0173-4
更新日期:2014-01-01 00:00:00
abstract::To ensure meaningful results in a clinical audit, as many hospitals as possible should participate. To optimise participation, the data collection process should either be performed by additional staff or be automated. Active participation may be promoted by offering relevant external parties insight into the actual q...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0652-8
更新日期:2019-11-21 00:00:00
abstract::Hip fractures are common in elderly people. Despite great progress in surgical care, the outcomes of these patients remain disappointing. This study determined pre-fracture hospital admission as a prognostic variable for inferior functional outcomes and increased mortality rates in the perioperative phase and in the f...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-017-0327-2
更新日期:2017-12-01 00:00:00
abstract::The microstructure of autologous bone grafts from men over 50 years old and postmenopausal women undergoing spinal fusion were evaluated using micro-CT. We demonstrated postmenopausal women, especially those with osteoporosis (OP) presented more serious microarchitectural deterioration of bone grafts. PURPOSE:This st...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0422-z
更新日期:2018-03-05 00:00:00
abstract::In this prospective multicenter study of osteoporotic vertebral fractures (OVFs), delayed union of OVF at 6-month follow-up caused prolonged pain, QOL impairment, ADL impairment, cognitive status deterioration, and vertebral collapse progression. PURPOSE:Delayed union following osteoporotic vertebral fracture display...
journal_title:Archives of osteoporosis
pub_type: 杂志文章,多中心研究
doi:10.1007/s11657-017-0411-7
更新日期:2017-12-28 00:00:00
abstract::We surveyed 573 physicians in the Middle East regarding osteoporosis management. Sixty percent had access to, but were not in charge of, densitometry reporting. Screening for secondary causes was common; 62% were aware of FRAX®; less than half used it. Medications were accessible, and most participants had concerns re...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0609-y
更新日期:2019-06-07 00:00:00
abstract::In Denmark, osteoporosis treatment is either handled by general practitioners or at more resource demanding specialist clinics. We evaluated the treatment adherence and persistence in the two settings, which were overall similar. The type of medical support did, however, differ and was provided to two very different p...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00774-9
更新日期:2020-06-25 00:00:00
abstract::In this study, we compared patients using the anticoagulant warfarin for more than a year with a control group with similar characteristics but without using the drug. We demonstrated worse BMD and bone quality by trabecular bone score (TBS) in patients using warfarin for more than 1 year. PURPOSE:Evaluate the bone m...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00770-z
更新日期:2020-07-06 00:00:00
abstract::Hospital care and mortality of diabetic and non-diabetic osteoporotic Asian patients undergoing hip fracture surgery were explored with no difference in length of hospitalization, incidence of post-operative complications, or mortality between diabetics and non-diabetics seen. Time to operation correlated with post-op...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0440-x
更新日期:2018-03-15 00:00:00
abstract:INTRODUCTION:We report a case of a patient sustaining multiple simultaneous vertebral fractures 5 months after Roux-en-Y gastric bypass (RYGB) surgery. Obesity is associated with increased rates of morbidity and mortality and obesity rates globally continue to rise. Bariatric surgical procedures are successful in induc...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0471-3
更新日期:2018-05-02 00:00:00
abstract::A hip fracture liaison service that was implemented in 2 hospitals in Alberta, Canada, co-managed by a nurse and physician, was effective for improving initiation of osteoporosis medication following hip fracture. PURPOSE:To examine implementation of an in-patient hip fracture liaison service (H-FLS) to improve osteo...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00751-2
更新日期:2020-06-02 00:00:00
abstract:UNLABELLED:Calf circumference has significant predictive value for bone mineral density (BMD) at hip and spine and for fracture at spine in both genders and hence may be used as a clinical risk factor for fracture when BMD is not available. INTRODUCTION:Lean muscle mass and higher regular physical ability has been sho...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-015-0221-8
更新日期:2015-01-01 00:00:00
abstract::Though smokers have poor clinical outcomes after treatment for fractures, the skeletal effects of smoking are still debated. Our results showed that female smokers had 33% higher cortical bone porosity. Smoking targets cortical compartment microstructure and mechanics, and micron-scale variables are essential to bette...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0504-y
更新日期:2018-08-23 00:00:00
abstract::The publisher has retracted this article [1] from Archives of Osteoporosis in order to publish in Osteoporosis International as originally intended by the authors and the Editors of Osteoporosis International. Springer Nature apologizes to readers and the authors. ...
journal_title:Archives of osteoporosis
pub_type: 已发布勘误,撤回出版物
doi:10.1007/s11657-019-0614-1
更新日期:2019-07-08 00:00:00