Abstract：
:In this study, we compared patients using the anticoagulant warfarin for more than a year with a control group with similar characteristics but without using the drug. We demonstrated worse BMD and bone quality by trabecular bone score (TBS) in patients using warfarin for more than 1 year. PURPOSE:Evaluate the bone mineral density (BMD) and the trabecular bone score (TBS) of patients taking warfarin for more than 1 year compared with a control group. METHODS:Male patients aged 25-65 years in warfarin use for more than 1 year were included. Patients answered a questionnaire regarding lifestyle habits and realized a dual X-ray densitometry (DXA) (lumbar spine and hip), and TBS was evaluated. RESULTS:From the 96 patients invited, 33 patients accepted to participate and comprised the warfarin group (WG), and 3 were excluded. The control group (CG) was composed of 21 individuals matched by age and race. The mean age of WG was 57.0 ± 7.6 and in the CG 54.0 ± 10.6 years (p = 0.095). The BMD in WG was lower than that in the CG in all sites (spine p < 0.001, total hip p = 0.001, and femoral neck p = 0.005). A longer time of warfarin use increased the likelihood of having low BMD (OR = 1.239, CI 1.064-1.674, p = 0.01), whereas high BMI decreased it (OR = 0.732, CI 0.533-0.918, p = 0.03). The TBS was lower in WG than the CG (p = 0.04). Lower TBS was associated with hypertension in both groups and to the hip BMD (neck and total) (p < 0.005) in the WG. In the multivariate analysis, only hypertension (- 0.10, CI - 0.17 to - 0.03, p = 0.008) and total hip BMD ( 0.26, CI 0.07-0.46, p = 0.009) influenced TBS. CONCLUSION:We demonstrated an association between worsening of BMD and bone quality in patients taking warfarin for more than 1 year.
journal_name
Arch Osteoporosjournal_title
Archives of osteoporosisauthors
Marques JVO,Nalevaiko JZ,Oliveira MF,Raetsch AWP,Marques GL,Petterle RR,Moreira CA,Borba VZCdoi
10.1007/s11657-020-00770-zsubject
Has Abstractpub_date
2020-07-06 00:00:00pages
102issue
1eissn
1862-3522issn
1862-3514pii
10.1007/s11657-020-00770-zjournal_volume
15pub_type
杂志文章abstract：:Giant cell tumor (GCT) of the bone, also called osteoclastoma, is a rare complication of Paget's bone disease. We report a patient from Southern Italy who developed a GCT infiltrating the neighboring tissues. The natural history and the therapeutic outcomes of this unique complication of Paget's bone disease are prese...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-009-0027-7
更新日期：2009-12-01 00:00:00
abstract：INTRODUCTION:We report a case of a patient sustaining multiple simultaneous vertebral fractures 5 months after Roux-en-Y gastric bypass (RYGB) surgery. Obesity is associated with increased rates of morbidity and mortality and obesity rates globally continue to rise. Bariatric surgical procedures are successful in induc...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-018-0471-3
更新日期：2018-05-02 00:00:00
abstract：:An observational study was carried out in two hospitals in patients > 65 years admitted for hip fracture. At 6 months, 15% of patients in the hospital with orthogeriatric standard care and 75% in the hospital with fracture liaison service were receiving bisphosphonates. PURPOSE:Many patients with fractures are discha...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-017-0373-9
更新日期：2017-12-11 00:00:00
abstract：:The article Estimated expenditures for hip fractures using merged healthcare insurance data for individuals aged ≥ 75 years and long-term care insurance claims data in Japan. ...
journal_title：Archives of osteoporosis
pub_type： 已发布勘误
doi：10.1007/s11657-019-0562-9
更新日期：2019-02-27 00:00:00
abstract：UNLABELLED:Changes in bed management and access policy aimed to shorten Canadian hip fracture hospital stay. Secular trends in hip fracture total, preoperative, and postoperative stay are unknown. Hip fracture stay shortened from 2004 to 2012, mostly from shortening postoperative stay. This may reflect changes in bed m...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-016-0264-5
更新日期：2016-01-01 00:00:00
abstract：:The purpose of this study is to establish the prevalence and determinants of fractures among 974 Lebanese schoolchildren aged 8-18. Fractures might be less common in the Lebanese pediatric population compared to western populations. Male gender and high SES are independent risk factors for fractures, while 25(OH)D and...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-019-0559-4
更新日期：2019-01-15 00:00:00
abstract：:Older men who participated in a sporting activity were less likely to sustain any fracture or major osteoporotic fracture over a 6-year follow-up period. PURPOSE:Regular weight-bearing physical activity can reduce fracture risk through an increase in bone strength, as well as reducing falls risk by improving muscle s...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-018-0459-z
更新日期：2018-04-19 00:00:00
abstract：:In this prospective multicenter study of osteoporotic vertebral fractures (OVFs), delayed union of OVF at 6-month follow-up caused prolonged pain, QOL impairment, ADL impairment, cognitive status deterioration, and vertebral collapse progression. PURPOSE:Delayed union following osteoporotic vertebral fracture display...
journal_title：Archives of osteoporosis
pub_type： 杂志文章,多中心研究
doi：10.1007/s11657-017-0411-7
更新日期：2017-12-28 00:00:00
abstract：:This study aims to determine the awareness of osteoporosis and factors that determine awareness of osteoporosis. Results showed that osteoporosis awareness was associated with age (p = 0.006) and occupation (p < 0.001) but not gender, marital status, and level of education. There is therefore need for educational inte...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-017-0342-3
更新日期：2017-12-01 00:00:00
abstract：:This analysis was performed in Zambian children who had a high prevalence of hypervitaminosis A, defined as > 1.0 μmol retinol/g liver. Bone parameters included markers of bone formation (P1NP), bone resorption (CTX), parathyroid hormone, calcium, vitamin A, and vitamin D. Low dietary vitamin A intake increased P1NP. ...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-019-0617-y
更新日期：2019-06-28 00:00:00
abstract：:The microstructure of autologous bone grafts from men over 50 years old and postmenopausal women undergoing spinal fusion were evaluated using micro-CT. We demonstrated postmenopausal women, especially those with osteoporosis (OP) presented more serious microarchitectural deterioration of bone grafts. PURPOSE:This st...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-018-0422-z
更新日期：2018-03-05 00:00:00
abstract：PURPOSE:Medical treatment of osteoporosis should preferably be both effective and have minimal side effects. The aim of the present study was to examine long-term benefits and risks of parathyroid hormone (PTH) treatment in compliant patients. METHODS:This is a nationwide retrospective cohort study based on national r...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-018-0444-6
更新日期：2018-05-02 00:00:00
abstract：:The effects of gluteal implants on bone mass remain unclear. Transgender women with ILS presented higher BMD in the hip compared with transgender women without implants, while no difference was observed in other sites. These results may be artifactual and suggest using spine/forearm sites for DXA in individuals with I...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-020-00824-2
更新日期：2020-09-22 00:00:00
abstract：:Hospital care and mortality of diabetic and non-diabetic osteoporotic Asian patients undergoing hip fracture surgery were explored with no difference in length of hospitalization, incidence of post-operative complications, or mortality between diabetics and non-diabetics seen. Time to operation correlated with post-op...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-018-0440-x
更新日期：2018-03-15 00:00:00
abstract：UNLABELLED:Serum concentrations of osteocalcin (OC) decrease and those of C-terminal telopeptide of type 1 collagen (CTX) increase during weight loss in adolescent girls with eating disorders (ED). The impact of weight loss on bone metabolism markers is greatest in premenarcheal girls. INTRODUCTION:Adolescents with ED...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-012-0090-3
更新日期：2012-01-01 00:00:00
abstract：:Osteoporosis has become an important health concern even in men. We aimed to analyze its prevalence and associated factors in Korean men. Low socioeconomic status, unhealthy lifestyle, and chronic kidney disease increased the risk. High-risk men even at young age need to evaluate bone mineral density, and proper inter...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-018-0506-9
更新日期：2018-08-20 00:00:00
abstract：:This study aimed to investigate the correlation between bone mineral density (BMD) with hemoglobin and ferritin levels in Palestinian patients suffering from various types of hemoglobinopathies. The study revealed the thresholds of hemoglobin and ferritin to protect against low BMD in these patients. PURPOSE:Iron ove...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-020-00853-x
更新日期：2020-11-13 00:00:00
abstract：:We investigated the effect of paravertebral muscle (PVM) on poor prognosis in osteoporotic vertebral fracture (OVF) and remaining lower back pain (LBP) in the thoracolumbar and lower lumbar regions. Additional OVF occurrence in the thoracolumbar and remaining LBP in the lumbar region was significantly related to PVM f...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-020-00866-6
更新日期：2021-01-03 00:00:00
abstract：:A systematic review and meta-analysis was conducted on the prevalence of osteoporosis in the Eastern Mediterranean Region. The overall pooled prevalence of osteoporosis was 24.4%. The prevalence has increased significantly over the recent years. The highest pooled prevalence was in Saudi Arabia (32.7%), and the lowest...
journal_title：Archives of osteoporosis
pub_type： 杂志文章,meta分析
doi：10.1007/s11657-018-0540-7
更新日期：2018-11-17 00:00:00
abstract：:To ensure meaningful results in a clinical audit, as many hospitals as possible should participate. To optimise participation, the data collection process should either be performed by additional staff or be automated. Active participation may be promoted by offering relevant external parties insight into the actual q...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-019-0652-8
更新日期：2019-11-21 00:00:00
abstract：:This study was undertaken to assess the effect of blood glucose on BMD and interactions with age, sex, and BMI in a Taiwanese population. Both obese and non-obese people with type 2 diabetes (T2DM) had higher BMD, at lumbar spine and femoral neck, compared with healthy subjects. In addition, the prevalence of osteopor...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-018-0494-9
更新日期：2018-07-16 00:00:00
abstract：INTRODUCTION:Hyperparathyroidism often presents with asymptomatic hypercalcemia or minimal, unspecific symptoms and the middle-age female is the predominant population. CASE REPORT:We reported a young Vietnamese female with primary hyperparathyroidism presented with chronic low back pain of about 1 year duration, simi...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-012-0072-5
更新日期：2012-01-01 00:00:00
abstract：:A workflow tool for measurements of vertebral heights on lateral spine radiographs based on automated placements of 6 points per vertebra was evaluated. The tool helps to standardize point placement among operators. Its success rate is very good in normal vertebrae but lower in vertebrae with more severe fractures. Ma...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-019-0577-2
更新日期：2019-02-11 00:00:00
abstract：:The publisher has retracted this article [1] from Archives of Osteoporosis in order to publish in Osteoporosis International as originally intended by the authors and the Editors of Osteoporosis International. Springer Nature apologizes to readers and the authors. ...
journal_title：Archives of osteoporosis
pub_type： 已发布勘误,撤回出版物
doi：10.1007/s11657-019-0614-1
更新日期：2019-07-08 00:00:00
abstract：:MrOS MsOS (Hong Kong) studies year 14 follow-up shows for subjects without baseline osteoporotic vertebral deformity, women's incident vertebral fracture (VF) rate was twice that of men. For subjects with vertebral deformity of baseline ≥ 20% height loss, counting subject, women's incident VF rate was three times high...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-020-00845-x
更新日期：2020-11-07 00:00:00
abstract：:In a large population-based study of Iran, the age-standardized prevalence of osteoporosis was 24.6% in men and 62.7% in women aged ≥ 60 years. Osteoporosis was negatively associated with body mass index in both sexes, and with diabetes in men and hypertriglyceridemia in women. PURPOSE:Population aging has made osteo...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-020-00872-8
更新日期：2021-01-21 00:00:00
abstract：:We surveyed 573 physicians in the Middle East regarding osteoporosis management. Sixty percent had access to, but were not in charge of, densitometry reporting. Screening for secondary causes was common; 62% were aware of FRAX®; less than half used it. Medications were accessible, and most participants had concerns re...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-019-0609-y
更新日期：2019-06-07 00:00:00
abstract：UNLABELLED:Calf circumference has significant predictive value for bone mineral density (BMD) at hip and spine and for fracture at spine in both genders and hence may be used as a clinical risk factor for fracture when BMD is not available. INTRODUCTION:Lean muscle mass and higher regular physical ability has been sho...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-015-0221-8
更新日期：2015-01-01 00:00:00
abstract：:Osteocalcin, the osteoblast-derived protein, has been shown to be modulated in patients with problematic glucose metabolism. Our systematic review and meta-analysis found that in humans, higher blood osteocalcin level is associated with lower body indices of fat. PURPOSE/INTRODUCTION:Osteocalcin (OC) was found to be ...
journal_title：Archives of osteoporosis
pub_type： 杂志文章,meta分析
doi：10.1007/s11657-020-00812-6
更新日期：2020-09-18 00:00:00
abstract：:Our study describes the clinical characteristics of patients with fragility fractures. It also shows there is a low knowledge about osteoporosis and its relation to fractures, in addition to the very poor adherence to medical advice and treatment. INTRODUCTION:Osteoporosis is a systemic skeletal disease associated wi...
journal_title：Archives of osteoporosis
pub_type： 杂志文章
doi：10.1007/s11657-019-0646-6
更新日期：2019-09-05 00:00:00
