Abstract:
INTRODUCTION:We report a case of a patient sustaining multiple simultaneous vertebral fractures 5 months after Roux-en-Y gastric bypass (RYGB) surgery. Obesity is associated with increased rates of morbidity and mortality and obesity rates globally continue to rise. Bariatric surgical procedures are successful in inducing sustained weight loss with many improved health outcomes. Potential complications include nutritional deficiencies and adverse effects on bone mineral metabolism with increased rates of fracture. CASE STUDY:We have recently cared for a 40-year-old female who sustained multiple vertebral fractures after bending forwards, occurring only 5 months after she underwent RYGB surgery, with post-operative weight loss of 55 kg. Blood tests performed several months after the fractures occurred revealed she had biochemical secondary hyperparathyroidism with low serum vitamin D levels. DISCUSSION:It has been previously demonstrated that RYGB surgery is associated with an increased incidence of fractures, and with reduction in bone mineral density. Patients undergoing bariatric surgery are frequently vitamin D deficient pre-operatively and show variable responses to vitamin D supplementation in the post-operative period. With particular reference to the RYGB procedure, there is evidence from several studies that bone mineral density is reduced at 12 and 24 post-operative months. To the best of our knowledge, this case may be the first time that multiple vertebral fractures have been documented so soon after weight loss surgery. It therefore highlights the growing conclusion that early consideration must be given to the maintenance of bone health in patients undergoing weight loss surgery.
journal_name
Arch Osteoporosjournal_title
Archives of osteoporosisauthors
Higgins SC,Papasavvas Gdoi
10.1007/s11657-018-0471-3subject
Has Abstractpub_date
2018-05-02 00:00:00pages
51issue
1eissn
1862-3522issn
1862-3514pii
10.1007/s11657-018-0471-3journal_volume
13pub_type
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00845-x
更新日期:2020-11-07 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-015-0221-8
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-017-0373-9
更新日期:2017-12-11 00:00:00
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pub_type: 杂志文章
doi:10.1007/s11657-009-0027-7
更新日期:2009-12-01 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0422-z
更新日期:2018-03-05 00:00:00
abstract::In this study, we attempted to determine the epidemiology and clinical characteristics of hip fracture in the elderly. We find that elderly people with hip fracture have multiple comorbidities and suffer numerous complications. INTRODUCTION:We attempted to explore the epidemiology and clinical characteristics of hip ...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0580-7
更新日期:2019-03-12 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-017-0342-3
更新日期:2017-12-01 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00769-6
更新日期:2020-06-25 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0504-y
更新日期:2018-08-23 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0459-z
更新日期:2018-04-19 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0652-8
更新日期:2019-11-21 00:00:00
abstract::We have characterised 997 hip fracture patients from a representative 45 Spanish hospitals, and followed them up prospectively for up to 4 months. Despite suboptimal surgical delays (average 59.1 hours), in-hospital mortality was lower than in Northern European cohorts. The secondary fracture prevention gap is unaccep...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0515-8
更新日期:2018-09-14 00:00:00
abstract::Osteocalcin, the osteoblast-derived protein, has been shown to be modulated in patients with problematic glucose metabolism. Our systematic review and meta-analysis found that in humans, higher blood osteocalcin level is associated with lower body indices of fat. PURPOSE/INTRODUCTION:Osteocalcin (OC) was found to be ...
journal_title:Archives of osteoporosis
pub_type: 杂志文章,meta分析
doi:10.1007/s11657-020-00812-6
更新日期:2020-09-18 00:00:00
abstract:UNLABELLED:Changes in bed management and access policy aimed to shorten Canadian hip fracture hospital stay. Secular trends in hip fracture total, preoperative, and postoperative stay are unknown. Hip fracture stay shortened from 2004 to 2012, mostly from shortening postoperative stay. This may reflect changes in bed m...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-016-0264-5
更新日期:2016-01-01 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-014-0173-4
更新日期:2014-01-01 00:00:00
abstract::This analysis was performed in Zambian children who had a high prevalence of hypervitaminosis A, defined as > 1.0 μmol retinol/g liver. Bone parameters included markers of bone formation (P1NP), bone resorption (CTX), parathyroid hormone, calcium, vitamin A, and vitamin D. Low dietary vitamin A intake increased P1NP. ...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0617-y
更新日期:2019-06-28 00:00:00
abstract::Osteoporosis has become an important health concern even in men. We aimed to analyze its prevalence and associated factors in Korean men. Low socioeconomic status, unhealthy lifestyle, and chronic kidney disease increased the risk. High-risk men even at young age need to evaluate bone mineral density, and proper inter...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0506-9
更新日期:2018-08-20 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章,随机对照试验
doi:10.1007/s11657-019-0561-x
更新日期:2019-01-18 00:00:00
abstract::The original version of this article, published on 05 August 2020, unfortunately contained a mistake. ...
journal_title:Archives of osteoporosis
pub_type: 杂志文章,已发布勘误
doi:10.1007/s11657-020-00813-5
更新日期:2020-09-08 00:00:00
abstract:UNLABELLED:Population ageing presents significant challenges for many developed nations. Accurately forecasting the likely future burden of age-related medical conditions, such as hip fracture, is critical. In this study, we present estimates of the current and future burden of hip fracture in NSW, Australia, providing...
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pub_type: 杂志文章
doi:10.1007/s11657-014-0200-5
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pub_type: 杂志文章
doi:10.1007/s11657-020-00856-8
更新日期:2021-01-07 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0560-y
更新日期:2019-01-14 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0577-2
更新日期:2019-02-11 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-018-0456-2
更新日期:2018-04-25 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-019-0594-1
更新日期:2019-03-22 00:00:00
abstract:UNLABELLED:Black women are generally regarded as being less prone to the development of osteoporosis. This study reports a similar prevalence of morphometric vertebral fractures in black (9.1 %) and white (5.0 %) South African women. Clinical risk factors and bone strength parameters contributed differently to fracture...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-015-0203-x
更新日期:2015-01-01 00:00:00
abstract::This study aims to evaluate factors affecting the quality of life (QOL) of hypoparathyroidism. While QOL is reduced in post-surgical and non-surgical groups, mental health seems to be less affected in non-surgical patients. Having an additional disease affects QOL negatively but having thyroid cancer may not change th...
journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00759-8
更新日期:2020-05-19 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00866-6
更新日期:2021-01-03 00:00:00
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journal_title:Archives of osteoporosis
pub_type: 杂志文章
doi:10.1007/s11657-020-00872-8
更新日期:2021-01-21 00:00:00
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pub_type: 杂志文章
doi:10.1007/s11657-017-0393-5
更新日期:2017-10-31 00:00:00