Novel Screen to Assess Bactericidal Activity of Compounds Against Non-replicating Mycobacterium abscessus.

abstract：:The Spirochaetes species cause many important diseases including syphilis and Lyme disease. Except for their containing a distinctive endoflagella, no other molecular or biochemical characteristics are presently known that are specific for either all Spirochaetes or its different families. We report detailed comparati...

journal_title：Frontiers in microbiology

authors： Gupta RS,Mahmood S,Adeolu M

更新日期：2013-07-30 00:00:00

abstract：:Retroviruses create permanently integrated proviruses that exist in the host genome. Retroviral genomes encode for functionally conserved gag, pro, pol, and env regions, as well as integrase (IN), which is required for retroviral integration. IN mediates viral genome insertion through 3' end processing of the viral DN...

journal_title：Frontiers in microbiology

authors： Bray S,Turnbull M,Hebert S,Douville RN

更新日期：2016-12-01 00:00:00

abstract：:This study was designed to evaluate the protection mechanism of oral administration of Clostridium butyricum against Salmonella enteritidis (SE) colonization in broilers. In the current study, 180 one-day-old healthy Arbor Acres (AA) broilers were meanly grouped into three, with three replicates of 20 birds each. An n...

journal_title：Frontiers in microbiology

authors： Zhao X,Yang J,Wang L,Lin H,Sun S

更新日期：2017-08-09 00:00:00

abstract：:RNA interference (RNAi) is a key regulatory pathway of gene expression in almost all eukaryotes. This mechanism relies on short non-coding RNA molecules (sRNAs) to recognize in a sequence-specific manner DNA or RNA targets leading to transcriptional or post-transcriptional gene silencing. To date, the fundamental role...

journal_title：Frontiers in microbiology

authors： Silvestri A,Turina M,Fiorilli V,Miozzi L,Venice F,Bonfante P,Lanfranco L

更新日期：2020-03-13 00:00:00

abstract：:[This corrects the article DOI: 10.3389/fmicb.2019.02612.]. ...

journal_title：Frontiers in microbiology

authors： Treven P,Mahnič A,Rupnik M,Golob M,Pirš T,Matijašić BB,Lorbeg PM

更新日期：2020-01-29 00:00:00

abstract：:Our understanding of microbial natural environments combines in situ experimentation with studies of specific interactions in laboratory-based setups. The purpose of this work was to develop, build and demonstrate the use of a microbial culture chamber enabling both in situ and laboratory-based studies. The design use...

journal_title：Frontiers in microbiology

authors： Thøgersen MS,Melchiorsen J,Ingham C,Gram L

更新日期：2018-07-30 00:00:00

abstract：:To estimate and predict the transmission dynamics of respiratory viruses, the estimation of the basic reproduction number, R0, is essential. Recently, approximate Bayesian computation methods have been used as likelihood free methods to estimate epidemiological model parameters, particularly R0. In this paper, we expl...

journal_title：Frontiers in microbiology

authors： Tessmer HL,Ito K,Omori R

更新日期：2018-03-02 00:00:00

abstract：:Eicosanoids are cellular metabolites, which shape the immune response, including inflammatory processes in macrophages. The effects of these lipid mediators on inflammation and bacterial pathogenesis are not clearly understood. Certain eicosanoids are suspected to act as molecular sensors for the recruitment of neutro...

journal_title：Frontiers in microbiology

authors： Sheppe AEF,Kummari E,Walker A,Richards A,Hui WW,Lee JH,Mangum L,Borazjani A,Ross MK,Edelmann MJ

更新日期：2018-10-31 00:00:00

abstract：:Dietary inclusions of baicalin and chlorogenic acid were beneficial for intestinal health in pigs. Nevertheless, it is unknown whether these plant-derived products had protection for intestine against bacterial challenge in chickens. This study was aimed at evaluating the potential mitigating effects of plant extracts...

journal_title：Frontiers in microbiology

authors： Wang WW,Jia HJ,Zhang HJ,Wang J,Lv HY,Wu SG,Qi GH

更新日期：2019-07-24 00:00:00

abstract：:Cefoperazone/sulbactam has been shown to be efficacious for the treatment of infections caused by Acinetobacter baumannii; however, the mechanism underlying resistance to this synergistic combination is not well understood. In the present study, two A. baumannii isolates, AB1845 and AB2092, were isolated from a patien...

journal_title：Frontiers in microbiology

authors： Liu X,Zheng H,Zhang W,Shen Z,Zhao M,Chen Y,Sun L,Shi J,Zhang J

更新日期：2016-08-19 00:00:00

abstract：:Sterile attenuation of Plasmodium parasites at the liver-stage either by irradiation or genetic modification, or at the blood-stage by chemoprophylaxis, has been shown to induce immune responses that can protect against subsequent wild-type infection. However, following certain interventions, parasite attenuation can ...

journal_title：Frontiers in microbiology

authors： Fernandes P,Frank R,Lewis MD,Mueller AK

更新日期：2014-12-02 00:00:00

abstract：:Shigella spp., the etiological agent of shigellosis or "bacillary dysentery," are responsible for considerable morbidity and mortality in excess of a million deaths globally per year. Although PCR-based techniques (such as PCR-based dipstick biosensors) have been used for the molecular diagnosis of infectious disease,...

journal_title：Frontiers in microbiology

authors： Wang Y,Wang Y,Xu J,Ye C

更新日期：2016-11-18 00:00:00

abstract：:To proliferate, antibiotic-producing Streptomyces undergo a complex developmental transition from vegetative growth to the production of aerial hyphae and spores. This morphological switch is controlled by the signaling molecule cyclic bis-(3',5') di-guanosine-mono-phosphate (c-di-GMP) that binds to the master develop...

journal_title：Frontiers in microbiology

authors： Al-Bassam MM,Haist J,Neumann SA,Lindenberg S,Tschowri N

更新日期：2018-10-23 00:00:00

abstract：:A large number of viral and bacterial organisms are responsible for community-acquired pneumonia (CAP) which contributes to substantial burden on health management. A new resequencing microarray (RPM-IVDC1) associated with targeted multiplex PCR was recently developed and validated for multiple respiratory viruses det...

journal_title：Frontiers in microbiology

authors： Shen H,Zhu B,Wang S,Mo H,Wang J,Li J,Zhang C,Zeng H,Guan L,Shi W,Zhang Y,Ma X

更新日期：2015-05-28 00:00:00

abstract：:The use of excess conventional Phosphorus (P) fertilizers to improve agricultural productivity, in order to meet constantly increasing global food demand, potentially causes surface and ground water pollution, waterway eutrophication, soil fertility depletion, and accumulation of toxic elements such as high concentrat...

journal_title：Frontiers in microbiology

authors： Alori ET,Glick BR,Babalola OO

更新日期：2017-06-02 00:00:00

abstract：:Host-cell expression of the ezrin protein is required for CXCR4 (X4)-tropic HIV-1 infection. Ezrin function is regulated by phosphorylation at threonine-567. This study investigates the role of ezrin phosphorylation in HIV-1 infection and virion release. We analyzed the effects of ezrin mutations involving substitutio...

journal_title：Frontiers in microbiology

authors： Kamiyama H,Izumida M,Umemura Y,Hayashi H,Matsuyama T,Kubo Y

更新日期：2018-08-27 00:00:00

abstract：:Recently, controllable, targeted proteolysis has emerged as one of the most promising new strategies to study essential genes and otherwise toxic mutations. One of the principal limitations preventing the wider adoption of this approach is due to the lack of easily identifiable species-specific degrons that can be use...

journal_title：Frontiers in microbiology

authors： Liu N,Chaudhry MT,Xie Z,Kreth J,Merritt J

更新日期：2017-12-19 00:00:00

abstract：:Influenza A virus (IAV) is a human respiratory pathogen that causes seasonal epidemics and occasional global pandemics with devastating levels of morbidity and mortality. Currently approved treatments against influenza are losing effectiveness, as new viral strains are often refractory to conventional treatments. Thus...

journal_title：Frontiers in microbiology

authors： Wang L,Li W,Li S

更新日期：2016-06-03 00:00:00

abstract：:The methanogenic biodegradation of crude oil involves the conversion of hydrocarbons to methanogenic substrates by syntrophic bacteria and subsequent methane production by methanogens. Assessing the metabolic roles played by various microbial species in syntrophic communities remains a challenge, but such information ...

journal_title：Frontiers in microbiology

authors： Fowler SJ,Toth CR,Gieg LM

更新日期：2016-04-22 00:00:00

abstract：:Estuarine sediments are significant repositories of anthropogenic contaminants, and thus knowledge of the impacts of pollution upon microbial communities in these environments is important to understand potential effects on estuaries as a whole. The Lagos lagoon (Nigeria) is one of Africa's largest estuarine ecosystem...

journal_title：Frontiers in microbiology

authors： Obi CC,Adebusoye SA,Ugoji EO,Ilori MO,Amund OO,Hickey WJ

更新日期：2016-08-05 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) have been demonstrated to play essential roles in many diseases. However, few studies have shown that lncRNAs take part in the pathogenesis of Chlamydia trachomatis (C. trachomatis). Here, we used a lncRNA microarray to detect the global lncRNA expression profiles in HeLa cells transfect...

journal_title：Frontiers in microbiology

authors： Wen Y,Chen H,Luo F,Zhao L,Shu M,Su S,Zhao Y,Huang Q,Li Z

更新日期：2020-12-17 00:00:00

abstract：:Extended-spectrum beta-lactamase- (ESBL-) and AmpC beta-lactamase- (AmpC-) producing Enterobacteriaceae pose a risk for both human and animal health. For livestock, highest prevalences have been reported in broiler chickens, which are therefore considered as a reservoir of multidrug-resistant bacteria. The possibility...

journal_title：Frontiers in microbiology

authors： Robé C,Blasse A,Merle R,Friese A,Roesler U,Guenther S

更新日期：2019-09-13 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) regulate gene expression at the epigenetic, transcriptional, or posttranscriptional level by interacting with protein, DNA, and RNA. Emerging evidence suggests that various lncRNAs are abnormally expressed and play indispensable roles in virus-triggered cancers. Besides, a growing number...

journal_title：Frontiers in microbiology

authors： Liu W,Zhang Y,Luo B

更新日期：2021-01-15 00:00:00

abstract：:The effects of nodulation properties of legumes on the rhizosphere bacterial community are still not clear. To determine the effects of nodulation phenotypes on bacterial communities in the rhizosphere of soybean plants, we performed high-throughput sequencing of the 16S rRNA gene to estimate the rhizosphere bacterial...

journal_title：Frontiers in microbiology

authors： Wang H,Gu C,Liu X,Yang C,Li W,Wang S

更新日期：2020-05-12 00:00:00

abstract：:The rice bacterial blight pathogen Xanthomonas oryzae pv. oryzae (Xoo) injects transcription activator-like effectors (TALEs) that bind and activate host "susceptibility" (S) genes important for disease. Clade III SWEET genes are major S genes for bacterial blight. The resistance genes xa5, which reduces TALE activity...

journal_title：Frontiers in microbiology

authors： Carpenter SCD,Mishra P,Ghoshal C,Dash PK,Wang L,Midha S,Laha GS,Lore JS,Kositratana W,Singh NK,Singh K,Patil PB,Oliva R,Patarapuwadol S,Bogdanove AJ,Rai R

更新日期：2018-11-13 00:00:00

abstract：:Polyhydroxyalkanoates (PHAs) are a family of biopolyesters accumulated by a variety of microorganisms as carbon and energy storage under starvation conditions. We focused on marine purple non-sulfur photosynthetic bacteria as host microorganisms for PHA production and developed a method for their isolation from natura...

journal_title：Frontiers in microbiology

authors： Higuchi-Takeuchi M,Morisaki K,Numata K

更新日期：2016-09-21 00:00:00

abstract：:In the present study, the β-glucosidase positive strain Lactobacillus plantarum F3. 3 was used as starter during the fermentation of Sicilian table olives (Nocellara Etnea cultivar) at two different salt concentrations (5 and 8%), in order to accelerate the debittering process. The latter was monitored through the inc...

journal_title：Frontiers in microbiology

authors： Pino A,Vaccalluzzo A,Solieri L,Romeo FV,Todaro A,Caggia C,Arroyo-López FN,Bautista-Gallego J,Randazzo CL

更新日期：2019-02-08 00:00:00

abstract：:Recent research has proven the ability of cold atmospheric plasma (CAP) for assuring food safety. A more flexible and transportable alternative is the use of plasma activated liquids (PAL), which are also known to have antimicrobial properties. However, within the context of food safety, little is known on its potenti...

journal_title：Frontiers in microbiology

authors： Smet C,Govaert M,Kyrylenko A,Easdani M,Walsh JL,Van Impe JF

更新日期：2019-07-04 00:00:00

abstract：:Fibronectin is a multidomain glycoprotein found ubiquitously in human body fluids and extracellular matrices of a variety of cell types from all human tissues and organs, including intestinal epithelial cells. Fibronectin plays a major role in the regulation of cell migration, tissue repair, and cell adhesion. Importa...

journal_title：Frontiers in microbiology

authors： Hymes JP,Klaenhammer TR

更新日期：2016-09-22 00:00:00

abstract：:Anti-retroviral therapy (ART) is crucial for controlling human immunodeficiency virus type-1 (HIV-1) infection. Recently, progress in identifying and characterizing highly potent broadly neutralizing antibodies has provided valuable templates for HIV-1 therapy and vaccine design. Nevertheless, HIV-1, like many RNA vir...

journal_title：Frontiers in microbiology

authors： Harada S,Yoshimura K

更新日期：2017-03-16 00:00:00