A High Throughput Assay for Screening Host Restriction Factors and Antivirals Targeting Influenza A Virus.

abstract：:RNA silencing mediated by microRNAs (miRNAs) is a recently discovered gene regulatory mechanism involved in various aspects of biology, such as development, cell differentiation and proliferation, and innate immunity against viral infections. miRNAs, which are a class of small (21-25 nucleotides) RNAs, target messenge...

journal_title：Frontiers in microbiology

authors： Tsunetsugu-Yokota Y,Yamamoto T

更新日期：2010-10-13 00:00:00

abstract：:Flavobacterium psychrophilum is a devastating bacterial pathogen of salmonids reared in freshwater worldwide. So far, serological diversity between isolates has been described but the underlying molecular factors remain unknown. By combining complete genome sequence analysis and the serotyping method proposed by Loren...

journal_title：Frontiers in microbiology

authors： Rochat T,Fujiwara-Nagata E,Calvez S,Dalsgaard I,Madsen L,Calteau A,Lunazzi A,Nicolas P,Wiklund T,Bernardet JF,Duchaud E

更新日期：2017-09-12 00:00:00

abstract：:The utilisation of the organic fraction of municipal solid waste as feedstock for bioethanol production could reduce the need for disposal of the ever-increasing amounts of municipal solid waste, especially in developing countries, and fits with the integrated goals of climate change mitigation and transport energy se...

journal_title：Frontiers in microbiology

authors： Carrillo-Barragan P,Bowler B,Dolfing J,Sallis P,Gray ND

更新日期：2019-04-09 00:00:00

abstract：:Chandipura Virus (CHPV) a negative-stranded RNA virus belonging to the Rhabdoviridae family, has been previously reported to bring about neuronal apoptosis by stimulating oxidative stress. Our in silico data suggested the involvement of Angiotensin II in intracellular Ca2+ secretion within CHPV infected cells that fur...

journal_title：Frontiers in microbiology

authors： Verma AK,Ghosh S,Basu A

更新日期：2018-07-06 00:00:00

abstract：:Spread and persistence of antibiotic resistance pose a severe threat to human health, yet there is still lack of knowledge about reservoirs of antibiotic resistant bacteria in the environment. We took the opportunity of the Joint Danube Survey 3 (JDS3), the world's biggest river research expedition of its kind in 2013...

journal_title：Frontiers in microbiology

authors： Kittinger C,Lipp M,Baumert R,Folli B,Koraimann G,Toplitsch D,Liebmann A,Grisold AJ,Farnleitner AH,Kirschner A,Zarfel G

更新日期：2016-05-03 00:00:00

abstract：:Studies focused on the pathological-radiological correlation of human Mycoplasma (M) pneumoniae pneumonia have rarely been reported. Therefore, we extensively reviewed the literature regarding pathological and radiological studies of Mycoplasma pneumonia, and compared findings between open lung biopsy specimen and com...

journal_title：Frontiers in microbiology

authors： Tanaka H

更新日期：2016-05-11 00:00:00

abstract：:Background:Tyrophagus putrescentiae is a ubiquitous mite species in soil, stored products and house dust and infests food and causes allergies in people. T. putrescentiae populations harbor different bacterial communities, including intracellular symbionts and gut bacteria. The spread of microorganisms via the fecal p...

journal_title：Frontiers in microbiology

authors： Hubert J,Nesvorna M,Sopko B,Smrz J,Klimov P,Erban T

更新日期：2018-10-30 00:00:00

abstract：:Microbial eukaryotes can play prominent roles in the Arctic marine ecosystem, but their diversity and variability is not well known in the ice-covered ecosystems. We determined the community composition of microbial eukaryotes in an Arctic under-ice spring bloom north of Svalbard using metabarcoding of DNA and RNA fro...

journal_title：Frontiers in microbiology

authors： Meshram AR,Vader A,Kristiansen S,Gabrielsen TM

更新日期：2017-06-28 00:00:00

abstract：:In our previous study we demonstrated that proteinase PrtP is able to impair bacteriocin LcnB activity, despite being produced by the same organism and encoded by the same plasmid. However, precise mechanism of this action, i.e., the exact cleavage site within LcnB bacteriocin, as well as its effect on antimicrobial a...

journal_title：Frontiers in microbiology

authors： Vukotic G,Polovic N,Mirkovic N,Jovcic B,Stanisavljevic N,Fira D,Kojic M

更新日期：2019-04-24 00:00:00

abstract：:Chlorpyrifos (CP) is one of the most widely used organophosphate pesticides in agriculture worldwide, but its extensive use has led to the contamination of various soil and water systems. Microbial bioremediation is considered to be one of the most viable options for the removal of CP from the environment; however, li...

journal_title：Frontiers in microbiology

authors： Rayu S,Nielsen UN,Nazaries L,Singh BK

更新日期：2017-04-04 00:00:00

abstract：:Traditionally, the shelf-life and safety of foods have been achieved by thermal processing. Low temperature long time and high temperature short time treatments are the most commonly used hurdles for the pasteurization of fluid foods and raw materials. However, the thermal treatments can reduce the product quality and...

journal_title：Frontiers in microbiology

authors： Patrignani F,Lanciotti R

更新日期：2016-08-03 00:00:00

abstract：:Particle-associated bacteria (PAB) and free-living bacteria (FLB) from aquatic environments during phytoplankton blooms differ in their physical distance from algae. Both the interactions within PAB and FLB community fractions and their relationship with the surrounding environmental properties are largely unknown. He...

journal_title：Frontiers in microbiology

authors： Yang C,Wang Q,Simon PN,Liu J,Liu L,Dai X,Zhang X,Kuang J,Igarashi Y,Pan X,Luo F

更新日期：2017-06-30 00:00:00

abstract：:The vertebrate gut teems with a large, diverse, and dynamic bacterial community that has pervasive effects on gut physiology, metabolism, and immunity. Under natural conditions, these microbes share their habitat with a similarly dynamic community of eukaryotes (helminths, protozoa, and fungi), many of which are well-...

journal_title：Frontiers in microbiology

authors： Leung JM,Graham AL,Knowles SCL

更新日期：2018-05-14 00:00:00

abstract：:The xylanases with high specific activity and resistance to harsh conditions are of high practical value for biomass utilization. In the present study, two new GH11 xylanase genes, MYCTH_56237 and MYCTH_49824, have been cloned from thermophilic fungus Myceliophthora thermophila and expressed in Pichia pastoris. The sp...

journal_title：Frontiers in microbiology

authors： Basit A,Liu J,Miao T,Zheng F,Rahim K,Lou H,Jiang W

更新日期：2018-02-14 00:00:00

abstract：:Pichia pastoris (Komagataella sp.) is broadly used for the production of secreted recombinant proteins. Due to the high rate of protein production, incorrectly folded proteins may accumulate in the endoplasmic reticulum (ER). To restore their proper folding, the cell triggers the unfolded protein response (UPR); howev...

journal_title：Frontiers in microbiology

authors： Raschmanová H,Zamora I,Borčinová M,Meier P,Weninger A,Mächler D,Glieder A,Melzoch K,Knejzlík Z,Kovar K

更新日期：2019-02-27 00:00:00

abstract：:Group B Streptococcus (GBS; Streptococcus agalactiae) is a leading cause of sepsis in neonates and pregnant mothers worldwide. Whereas the hyper-virulent serogroup III clonal cluster 17 has been associated with neonatal disease and meningitis, serogroup III ST283 was recently implicated in invasive disease among non-p...

journal_title：Frontiers in microbiology

authors： Yang Y,Luo M,Zhou H,Li C,Luk A,Zhao G,Fung K,Ip M

更新日期：2019-01-23 00:00:00

abstract：:The success of Ericaceae in stressful habitats enriched in heavy metals has been ascribed to the distinctive abilities of their mycorrhizal fungal partners to withstand heavy metal stress and to enhance metal tolerance in the host plant. Whereas heavy metal tolerance has been extensively investigated in some ericoid m...

journal_title：Frontiers in microbiology

authors： Casarrubia S,Martino E,Daghino S,Kohler A,Morin E,Khouja HR,Murat C,Barry KW,Lindquist EA,Martin FM,Perotto S

更新日期：2020-03-09 00:00:00

abstract：:Viruses are a primary influence on microbial mortality in the global ocean. The impacts of viruses on their microbial hosts in low-energy environments are poorly explored and are the focus of this study. To investigate the role of viruses in mediating mortality in low-energy environments where contacts between viruses...

journal_title：Frontiers in microbiology

authors： Colangelo-Lillis J,Wing BA,Raymond-Bouchard I,Whyte LG

更新日期：2017-01-23 00:00:00

abstract：:Protein export in bacteria is facilitated by the canonical SecB chaperone, which binds to unfolded precursor proteins, maintains them in a translocation competent state and specifically cooperates with the translocase motor SecA to ensure their proper targeting to the Sec translocon at the cytoplasmic membrane. Beside...

journal_title：Frontiers in microbiology

authors： Sala A,Bordes P,Genevaux P

更新日期：2014-12-05 00:00:00

abstract：BACKGROUND:Antibiotic treatment of chronic Q fever is cumbersome and of long duration. To monitor treatment, there is a need for alternative biomarkers. Coxiella burnetii-specific interferon (IFN)-γ and interleukin (IL)-2 production reflect the type of effector and memory T-cell response. In chronic Q fever, C. burneti...

journal_title：Frontiers in microbiology

authors： Schoffelen T,Wegdam-Blans MC,Ammerdorffer A,Pronk MJ,Soethoudt YE,Netea MG,van der Meer JW,Bleeker-Rovers CP,van Deuren M

更新日期：2015-02-12 00:00:00

abstract：:The pyogenic streptococci group includes pathogenic species for humans and other animals and has been associated with enduring morbidity and high mortality. The main reason for the treatment failure of streptococcal infections is the increased resistance to antibiotics. In recent years, infectious diseases caused by p...

journal_title：Frontiers in microbiology

authors： Alves-Barroco C,Rivas-García L,Fernandes AR,Baptista PV

更新日期：2020-10-06 00:00:00

abstract：:In Agrobacterium-mediated transformation (AMT) of plants, a single-strand (ss) T-DNA covalently linked with a VirD2 protein moves through a bacterial type IV secretion channel called VirB/D4. This transport system originates from conjugal plasmid transfer systems of bacteria. The relaxase VirD2 and its equivalent prot...

journal_title：Frontiers in microbiology

authors： Ohmine Y,Kiyokawa K,Yunoki K,Yamamoto S,Moriguchi K,Suzuki K

更新日期：2018-05-28 00:00:00

abstract：:Microbial diversity present on grapes in wineries, and throughout fermentation has been associated with important metabolites for final wine quality. Although microbiome-metabolome associations have been well characterized and could be used as indicators of wine quality, the impact of regionality on the microbiome and...

journal_title：Frontiers in microbiology

authors： Wang HL,Hopfer H,Cockburn DW,Wee J

更新日期：2021-01-11 00:00:00

abstract：:Mycobacteria are able to form dormant cells, which survive for a long time without multiplication. The molecular mechanisms behind prolonged survival of dormant cells are not fully described. In particular, little information is known on biochemical processes which might take place in cells under dormancy. To gain ins...

journal_title：Frontiers in microbiology

authors： Trutneva K,Shleeva M,Nikitushkin V,Demina G,Kaprelyants A

更新日期：2018-09-04 00:00:00

abstract：:Staphylococcus epidermidis is a ubiquitous commensal of human skin. The widespread use of indwelling medical devices in modern medicine provides an opportunity for it to cause infections. Disease causing isolates can come from many different genetic backgrounds. Multiply antibiotic resistant strains have spread global...

journal_title：Frontiers in microbiology

authors： Foster TJ

更新日期：2020-07-29 00:00:00

abstract：:Fungi represent a rich source of bioactive metabolites and some are marketed as alternatives to synthetic agrochemicals against plant pathogens. However, the culturability of fungal strains in artificial laboratory conditions is still limited and the standard mono-cultures do not reflect their full spectrum chemical d...

journal_title：Frontiers in microbiology

authors： Oppong-Danquah E,Parrot D,Blümel M,Labes A,Tasdemir D

更新日期：2018-09-06 00:00:00

abstract：:Cyanobacteria, a group of photosynthetic prokaryotes, oscillate between day and night time metabolisms with concomitant oscillations in gene expression in response to light/dark cycles (LD). The oscillations in gene expression have been shown to sustain in constant light (LL) with a free running period of 24 h in a mo...

journal_title：Frontiers in microbiology

authors： Gaudana SB,Krishnakumar S,Alagesan S,Digmurti MG,Viswanathan GA,Chetty M,Wangikar PP

更新日期：2013-12-06 00:00:00

abstract：:The abundance of methane in shale gas and of other gases such as carbon monoxide, hydrogen, and carbon dioxide as chemical process byproducts has motivated the use of gas fermentation for bioproduction. Recent advances in metabolic engineering and synthetic biology allow for engineering of microbes metabolizing a vari...

journal_title：Frontiers in microbiology

authors： Nazem-Bokaee H,Maranas CD

更新日期：2018-08-24 00:00:00

abstract：:Increased use of vancomycin has led to the emergence of vancomycin-intermediate Staphylococcus aureus (VISA). To investigate the mechanism of VISA development, 39 methicillin-susceptible strains and 3 MRSA strains were treated with vancomycin to induce non-susceptibility, and mutations in six genes were analyzed. All ...

journal_title：Frontiers in microbiology

authors： Wang Y,Li X,Jiang L,Han W,Xie X,Jin Y,He X,Wu R

更新日期：2017-01-10 00:00:00

abstract：:The effects of environmental and dispersal processes on macrofungi community assembly remain unclear. Further, it is not well understood if community assembly differs for different functional guilds of macrofungi, e.g., soil and rotten-wood macrofungi. In this study, using 2433 macrofungi sporocarps belonging to 217 s...

journal_title：Frontiers in microbiology

authors： Chen Y,Svenning JC,Wang X,Cao R,Yuan Z,Ye Y

更新日期：2018-01-23 00:00:00