Can Machines Learn Respiratory Virus Epidemiology?: A Comparative Study of Likelihood-Free Methods for the Estimation of Epidemiological Dynamics.

Abstract:

:To estimate and predict the transmission dynamics of respiratory viruses, the estimation of the basic reproduction number, R0, is essential. Recently, approximate Bayesian computation methods have been used as likelihood free methods to estimate epidemiological model parameters, particularly R0. In this paper, we explore various machine learning approaches, the multi-layer perceptron, convolutional neural network, and long-short term memory, to learn and estimate the parameters. Further, we compare the accuracy of the estimates and time requirements for machine learning and the approximate Bayesian computation methods on both simulated and real-world epidemiological data from outbreaks of influenza A(H1N1)pdm09, mumps, and measles. We find that the machine learning approaches can be verified and tested faster than the approximate Bayesian computation method, but that the approximate Bayesian computation method is more robust across different datasets.

journal_name

Front Microbiol

authors

Tessmer HL,Ito K,Omori R

doi

10.3389/fmicb.2018.00343

subject

Has Abstract

pub_date

2018-03-02 00:00:00

pages

343

issn

1664-302X

journal_volume

9

pub_type

杂志文章
  • Nitrogen Fixation and Molecular Oxygen: Comparative Genomic Reconstruction of Transcription Regulation in Alphaproteobacteria.

    abstract::Biological nitrogen fixation plays a crucial role in the nitrogen cycle. An ability to fix atmospheric nitrogen, reducing it to ammonium, was described for multiple species of Bacteria and Archaea. The transcriptional regulatory network for nitrogen fixation was extensively studied in several representatives of the cl...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.01343

    authors: Tsoy OV,Ravcheev DA,Čuklina J,Gelfand MS

    更新日期:2016-08-26 00:00:00

  • YtrASa, a GntR-Family Transcription Factor, Represses Two Genetic Loci Encoding Membrane Proteins in Sulfolobus acidocaldarius.

    abstract::In bacteria, the GntR family is a widespread family of transcription factors responsible for the regulation of a myriad of biological processes. In contrast, despite their occurrence in archaea only a little information is available on the function of GntR-like transcription factors in this domain of life. The thermoa...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.02084

    authors: Lemmens L,Tilleman L,De Koning E,Valegård K,Lindås AC,Van Nieuwerburgh F,Maes D,Peeters E

    更新日期:2019-09-10 00:00:00

  • Extracellular Trap Formation in Response to Trypanosoma cruzi Infection in Granulocytes Isolated From Dogs and Common Opossums, Natural Reservoir Hosts.

    abstract::Granulocytes mediate the first line of defense against infectious diseases in humans as well as animals and they are well known as multitasking cells. They can mediate antimicrobial activity by different strategies depending on the pathogen they encounter. Besides phagocytosis, a key strategy against extracellular pat...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00966

    authors: de Buhr N,Bonilla MC,Jimenez-Soto M,von Köckritz-Blickwede M,Dolz G

    更新日期:2018-05-15 00:00:00

  • Ecogenomics and Taxonomy of Cyanobacteria Phylum.

    abstract::Cyanobacteria are major contributors to global biogeochemical cycles. The genetic diversity among Cyanobacteria enables them to thrive across many habitats, although only a few studies have analyzed the association of phylogenomic clades to specific environmental niches. In this study, we adopted an ecogenomics strate...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.02132

    authors: Walter JM,Coutinho FH,Dutilh BE,Swings J,Thompson FL,Thompson CC

    更新日期:2017-11-14 00:00:00

  • Respiratory Commensal Bacteria Corynebacterium pseudodiphtheriticum Improves Resistance of Infant Mice to Respiratory Syncytial Virus and Streptococcus pneumoniae Superinfection.

    abstract::Corynebacterium pseudodiphtheriticum is a Gram-positive bacterium found as a member of the normal microbiota of the upper respiratory tract. It was suggested that C. pseudodiphtheriticum may be potentially used as a next-generation probiotic for nasal application, although no deep studies were performed in this regard...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01613

    authors: Kanmani P,Clua P,Vizoso-Pinto MG,Rodriguez C,Alvarez S,Melnikov V,Takahashi H,Kitazawa H,Villena J

    更新日期:2017-08-23 00:00:00

  • PBHMDA: Path-Based Human Microbe-Disease Association Prediction.

    abstract::With the advance of sequencing technology and microbiology, the microorganisms have been found to be closely related to various important human diseases. The increasing identification of human microbe-disease associations offers important insights into the underlying disease mechanism understanding from the perspectiv...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.00233

    authors: Huang ZA,Chen X,Zhu Z,Liu H,Yan GY,You ZH,Wen Z

    更新日期:2017-02-22 00:00:00

  • Oral Administration of Heat-Killed Mycobacterium manresensis Delays Progression toward Active Tuberculosis in C3HeB/FeJ Mice.

    abstract::Low-dose tolerance using heat-killed mycobacteria has been tested as a means of stopping progression toward active tuberculosis (TB) lesions in a human-like murine model using C3HeB/FeJ mice. In the present study, we studied the effect of different treatment schedules with heat-killed non-tuberculous-mycobacteria (NTM...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.01482

    authors: Cardona P,Marzo-Escartín E,Tapia G,Díaz J,García V,Varela I,Vilaplana C,Cardona PJ

    更新日期:2016-01-05 00:00:00

  • Effects of Lactobacillus fermentum CQPC04 on Lipid Reduction in C57BL/6J Mice.

    abstract::Probiotics are functional foods that can effectively regulate lipid reduction and maintain body health. In this study, a strain of Lactobacillus fermentum CQPC04 (LF-CQPC04) isolated from traditional naturally fermented vegetables (Sichuan pickles) was studied, and its effects on lipid reduction in mice, as well as it...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.573586

    authors: Yi R,Tan F,Zhou X,Mu J,Li L,Du X,Yang Z,Zhao X

    更新日期:2020-09-03 00:00:00

  • Protein-Protein Interactions in Candida albicans.

    abstract::Despite being one of the most important human fungal pathogens, Candida albicans has not been studied extensively at the level of protein-protein interactions (PPIs) and data on PPIs are not readily available in online databases. In January 2018, the database called "Biological General Repository for Interaction Datas...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2019.01792

    authors: Schoeters F,Van Dijck P

    更新日期:2019-08-07 00:00:00

  • Suspended Materials in River Waters Differentially Enrich Class 1 Integron- and IncP-1 Plasmid-Carrying Bacteria in Sediments.

    abstract::Aquatic ecosystems are frequently considered as the final receiving environments of anthropogenic pollutants such as pharmaceutical residues or antibiotic resistant bacteria, and as a consequence tend to form reservoirs of antibiotic resistance genes. Considering the global threat posed by the antibiotic resistance, t...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.01443

    authors: De la Cruz Barrón M,Merlin C,Guilloteau H,Montargès-Pelletier E,Bellanger X

    更新日期:2018-07-02 00:00:00

  • Genetic Basis and Clonal Population Structure of Antibiotic Resistance in Campylobacter jejuni Isolated From Broiler Carcasses in Belgium.

    abstract::Human campylobacteriosis is the leading food-borne zoonosis in industrialized countries. This study characterized the clonal population structure, antimicrobial resistance profiles and occurrence of antimicrobial resistance determinants of a set of Campylobacter jejuni strains isolated from broiler carcasses in Belgiu...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.01014

    authors: Elhadidy M,Miller WG,Arguello H,Álvarez-Ordóñez A,Duarte A,Dierick K,Botteldoorn N

    更新日期:2018-05-17 00:00:00

  • Differential NtcA Responsiveness to 2-Oxoglutarate Underlies the Diversity of C/N Balance Regulation in Prochlorococcus.

    abstract::Previous studies showed differences in the regulatory response to C/N balance in Prochlorococcus with respect to other cyanobacteria, but no information was available about its causes, or the ecological advantages conferred to thrive in oligotrophic environments. We addressed the changes in key enzymes (glutamine synt...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.02641

    authors: Domínguez-Martín MA,López-Lozano A,Clavería-Gimeno R,Velázquez-Campoy A,Seidel G,Burkovski A,Díez J,García-Fernández JM

    更新日期:2018-01-09 00:00:00

  • Detection of autotrophic verrucomicrobial methanotrophs in a geothermal environment using stable isotope probing.

    abstract::Genomic analysis of the methanotrophic verrucomicrobium "Methylacidiphilum infernorum" strain V4 has shown that most pathways conferring its methanotrophic lifestyle are similar to those found in proteobacterial methanotrophs. However, due to the large sequence divergence of its methane monooxygenase-encoding genes (p...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2012.00303

    authors: Sharp CE,Stott MB,Dunfield PF

    更新日期:2012-08-17 00:00:00

  • Designing and Engineering Methylorubrum extorquens AM1 for Itaconic Acid Production.

    abstract::Methylorubrum extorquens (formerly Methylobacterium extorquens) AM1 is a methylotrophic bacterium with a versatile lifestyle. Various carbon sources including acetate, succinate and methanol are utilized by M. extorquens AM1 with the latter being a promising inexpensive substrate for use in the biotechnology industry....

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.01027

    authors: Lim CK,Villada JC,Chalifour A,Duran MF,Lu H,Lee PKH

    更新日期:2019-05-09 00:00:00

  • Use of a Neonatal-Mouse Model to Characterize Vaccines and Strategies for Overcoming the High Susceptibility and Severity of Pertussis in Early Life.

    abstract::Newborns and unvaccinated infants, compared to other age groups, are more susceptible to pertussis infection, manifesting severe symptoms leading to a higher mortality. The recent increase in pertussis cases demands more effective strategies to overcome this major health problem. In parallel with maternal-immunization...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.00723

    authors: Martin Aispuro P,Ambrosis N,Zurita ME,Gaillard ME,Bottero D,Hozbor DF

    更新日期:2020-04-17 00:00:00

  • A Strain of an Emerging Indian Xanthomonas oryzae pv. oryzae Pathotype Defeats the Rice Bacterial Blight Resistance Gene xa13 Without Inducing a Clade III SWEET Gene and Is Nearly Identical to a Recent Thai Isolate.

    abstract::The rice bacterial blight pathogen Xanthomonas oryzae pv. oryzae (Xoo) injects transcription activator-like effectors (TALEs) that bind and activate host "susceptibility" (S) genes important for disease. Clade III SWEET genes are major S genes for bacterial blight. The resistance genes xa5, which reduces TALE activity...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,收录出版

    doi:10.3389/fmicb.2018.02703

    authors: Carpenter SCD,Mishra P,Ghoshal C,Dash PK,Wang L,Midha S,Laha GS,Lore JS,Kositratana W,Singh NK,Singh K,Patil PB,Oliva R,Patarapuwadol S,Bogdanove AJ,Rai R

    更新日期:2018-11-13 00:00:00

  • Fungal metabolic gene clusters-caravans traveling across genomes and environments.

    abstract::Metabolic gene clusters (MGCs), physically co-localized genes participating in the same metabolic pathway, are signature features of fungal genomes. MGCs are most often observed in specialized metabolism, having evolved in individual fungal lineages in response to specific ecological needs, such as the utilization of ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2015.00161

    authors: Wisecaver JH,Rokas A

    更新日期:2015-03-03 00:00:00

  • How community ecology can improve our understanding of cholera dynamics.

    abstract::Understanding the seasonal emergence and reemergence of cholera is challenging due to the complex dynamics of different protagonists. The abundance of Vibrio cholerae, the causative agent of cholera and a natural inhabitant of aquatic environments, fluctuates according to abiotic, and biotic factors. Among the biotic ...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2014.00137

    authors: Constantin de Magny G,Hasan NA,Roche B

    更新日期:2014-04-02 00:00:00

  • Lipoproteins in Gram-Positive Bacteria: Abundance, Function, Fitness.

    abstract::When one thinks of the Gram+ cell wall, the peptidoglycan (PG) scaffold in particular comes to mind. However, the cell wall also consists of many other components, for example those that are covalently linked to the PG: the wall teichoic acid and the cell wall proteins tethered by the sortase. In addition, there are c...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2020.582582

    authors: Nguyen MT,Matsuo M,Niemann S,Herrmann M,Götz F

    更新日期:2020-09-18 00:00:00

  • Inactivation of Spoilage Yeasts by Mentha spicata L. and M. × villosa Huds. Essential Oils in Cashew, Guava, Mango, and Pineapple Juices.

    abstract::This study evaluated the efficacy of the essential oil from Mentha spicata L. (MSEO) and M. × villosa Huds. (MVEO) to inactivate Candida albicans, C. tropicalis, Pichia anomala and Saccharomyces cerevisiae in Sabouraud dextrose broth and cashew, guava, mango, and pineapple juices during 72 h of refrigerated storage. T...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.01111

    authors: da Cruz Almeida ET,de Medeiros Barbosa I,Tavares JF,Barbosa-Filho JM,Magnani M,de Souza EL

    更新日期:2018-05-25 00:00:00

  • In vitro Determination of Extracellular Proteins from Xylella fastidiosa.

    abstract::The phytopathogen Xylella fastidiosa causes economic losses in important agricultural crops. Xylem vessel occlusion caused by biofilm formation is the major mechanism underlying the pathogenicity of distinct strains of X. fastidiosa. Here, we provide a detailed in vitro characterization of the extracellular proteins o...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2016.02090

    authors: Mendes JS,Santiago AS,Toledo MA,Horta MA,de Souza AA,Tasic L,de Souza AP

    更新日期:2016-12-26 00:00:00

  • Protein Composition of Mycobacterium smegmatis Differs Significantly Between Active Cells and Dormant Cells With Ovoid Morphology.

    abstract::Mycobacteria are able to form dormant cells, which survive for a long time without multiplication. The molecular mechanisms behind prolonged survival of dormant cells are not fully described. In particular, little information is known on biochemical processes which might take place in cells under dormancy. To gain ins...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.02083

    authors: Trutneva K,Shleeva M,Nikitushkin V,Demina G,Kaprelyants A

    更新日期:2018-09-04 00:00:00

  • The Dynamic Distribution of Small-Tail Han Sheep Microbiota across Different Intestinal Segments.

    abstract::The sheep intestinal tract is characterized by a diverse microbial ecosystem that is vital for the host to digest diet material. The importance of gut microbiota (GM) of animals has also been widely acknowledged because of its pivotal roles in the health and well-being of animals. However, there are no relevant studie...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2018.00032

    authors: Zhang H,Shao M,Huang H,Wang S,Ma L,Wang H,Hu L,Wei K,Zhu R

    更新日期:2018-01-31 00:00:00

  • From Farms to Markets: Gram-Negative Bacteria Resistant to Third-Generation Cephalosporins in Fruits and Vegetables in a Region of North Africa.

    abstract::The role of food in human exposure to antimicrobial-resistant bacteria is a growing food safety issue. The contribution of fruits and vegetables eaten raw to this exposure is still unclear. The evaluation of contamination levels of fruits, vegetables and the agricultural environment by third-generation cephalosporin (...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.01569

    authors: Mesbah Zekar F,Granier SA,Marault M,Yaici L,Gassilloud B,Manceau C,Touati A,Millemann Y

    更新日期:2017-08-24 00:00:00

  • Modeling Reveals the Role of Aging and Glucose Uptake Impairment in L1A1 Listeria monocytogenes Biofilm Life Cycle.

    abstract::Listeria monocytogenes is a food-borne pathogen that can persist in food processing plants by forming biofilms on abiotic surfaces. The benefits that bacteria can gain from living in a biofilm, i.e., protection from environmental factors and tolerance to biocides, have been linked to the biofilm structure. Different L...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2017.02118

    authors: Balsa-Canto E,Vilas C,López-Núñez A,Mosquera-Fernández M,Briandet R,Cabo ML,Vázquez C

    更新日期:2017-11-01 00:00:00

  • Antimicrobial Metabolites Produced by Penicillium mallochii CCH01 Isolated From the Gut of Ectropis oblique, Cultivated in the Presence of a Histone Deacetylase Inhibitor.

    abstract::Three chemical epigenetic modifiers [5-azacytidine, nicotinamide, and suberoylanilide hydroxamic acid (SAHA)] were applied to induce the metabolites of Penicillium mallochii CCH01, a fungus isolated from the gut of Ectropis oblique. Metabolite profiles of P. mallochii CCH01 were obviously changed by SAHA treatment. Fo...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2019.02186

    authors: Zhang S,Fang H,Yin C,Wei C,Hu J,Zhang Y

    更新日期:2019-10-02 00:00:00

  • Metagenomic analysis reveals that modern microbialites and polar microbial mats have similar taxonomic and functional potential.

    abstract::Within the subarctic climate of Clinton Creek, Yukon, Canada, lies an abandoned and flooded open-pit asbestos mine that harbors rapidly growing microbialites. To understand their formation we completed a metagenomic community profile of the microbialites and their surrounding sediments. Assembled metagenomic data reve...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2015.00966

    authors: White RA 3rd,Power IM,Dipple GM,Southam G,Suttle CA

    更新日期:2015-09-23 00:00:00

  • Lipids in Aspergillus flavus-maize interaction.

    abstract::In some filamentous fungi, the pathways related to the oxidative stress and oxylipins production are involved both in the process of host-recognition and in the pathogenic phase. In fact, recent studies have shown that the production of oxylipins in filamentous fungi, yeasts and chromists is also related to the develo...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2014.00074

    authors: Scarpari M,Punelli M,Scala V,Zaccaria M,Nobili C,Ludovici M,Camera E,Fabbri AA,Reverberi M,Fanelli C

    更新日期:2014-02-27 00:00:00

  • The many forms of a pleomorphic bacterial pathogen-the developmental network of Legionella pneumophila.

    abstract::Legionella pneumophila is a natural intracellular bacterial parasite of free-living freshwater protozoa and an accidental human pathogen that causes Legionnaires' disease. L. pneumophila differentiates, and does it in style. Recent experimental data on L. pneumophila's differentiation point at the existence of a compl...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章,评审

    doi:10.3389/fmicb.2014.00670

    authors: Robertson P,Abdelhady H,Garduño RA

    更新日期:2014-12-22 00:00:00

  • PacBio and Illumina MiSeq Amplicon Sequencing Confirm Full Recovery of the Bacterial Community After Subacute Ruminal Acidosis Challenge in the RUSITEC System.

    abstract::The impact of subacute rumen acidosis (SARA) on the rumen bacterial community has been frequently studied in in vivo trials. Here we investigated whether these alterations can be mirrored by using the rumen simulation technique (RUSITEC) as an in vitro model for this disease. We hypothezised that the bacterial communi...

    journal_title:Frontiers in microbiology

    pub_type: 杂志文章

    doi:10.3389/fmicb.2020.01813

    authors: Brede M,Orton T,Pinior B,Roch FF,Dzieciol M,Zwirzitz B,Wagner M,Breves G,Wetzels SU

    更新日期:2020-08-07 00:00:00