circRNAs (hsa_circ_00156, hsa_circ _000224, and hsa_circ _000520) are novel potential biomarkers in hepatocellular carcinoma.

abstract：:The Wilms' tumor-associated gene WT1 encodes a tumor suppressor gene, which is implicated in renal differentiation and development of adult urogenital system. Wilms' tumor 1-associating protein (WTAP) is initially identified as a nuclear protein that specifically interacts with WT1 in both in vitro and in vivo assays....

journal_title：Journal of cellular biochemistry

authors： Xie W,Wei L,Guo J,Guo H,Song X,Sheng X

更新日期：2019-02-12 00:00:00

abstract：:Heme oxygenase (HO-1) is a stress protein that has been suggested to participate in defense mechanisms against agents that induce oxidative injury such as hemoglobin/heme, hypoxia-ischemia and cytokines. Overexpression of HO-1 in endothelial cells (EC) might, therefore, protect against oxidative stress produced under ...

journal_title：Journal of cellular biochemistry

authors： Deramaudt BM,Braunstein S,Remy P,Abraham NG

更新日期：1998-01-01 00:00:00

abstract：:The sex steroid hormones, androgens and estrogens, via their respective nuclear receptors, regulate bone mineral density in humans and mice. Very little is known about the direct targets of the androgen and estrogen receptors in bone cells. First, models of hormone and receptor deficiency in mouse and human bone are d...

journal_title：Journal of cellular biochemistry

authors： Krum SA

更新日期：2011-02-01 00:00:00

abstract：:The role of insulin-like growth factor-I (IGF-I) in regulating estrogen receptor-alpha (ER-alpha) gene expression and activity was investigated in the human breast cancer cell line MCF-7. Treatment of cells with 40 ng/ml IGF-I resulted in a 60% decrease in ER-alpha protein concentration by 3 h, and the amount of ER-al...

journal_title：Journal of cellular biochemistry

authors： Stoica A,Saceda M,Fakhro A,Joyner M,Martin MB

更新日期：2000-01-01 00:00:00

abstract：:Extracts of serum-free conditioned medium from human rhabdomyosarcoma A673 cells contain high molecular weight (HMW) transforming growth factors (TGFs) that can be partially purified by Bio-Gel P-100 and carboxymethyl (CM)-cellulose chromatography (Todaro et al: Proc Natl Acad Sci USA 77:5258, 1980). Reverse-phase hig...

journal_title：Journal of cellular biochemistry

authors： Stromberg K,Hudgins WR,Fryling CM,Hazarika P,Dedman JR,Pardue RL,Hargreaves WR,Orth DN

更新日期：1986-01-01 00:00:00

abstract：:Phosphoproteins produced by the incubation of crude extracts of Salmonella typhimurium and Escherichia coli with either [32P]phosphoenolpyruvate or [gamma 32P]ATP have been resolved and detected using sodium dodecyl sulphate polyacrylamide gel electrophoresis and autoradiography. Simple techniques were found such that...

journal_title：Journal of cellular biochemistry

authors： Waygood EB,Mattoo RL,Peri KG

更新日期：1984-01-01 00:00:00

abstract：:We have examined the effect of polyoma virus infection of primary mouse embryo cells on the tyrosyl kinase activity associated with the cellular src gene product, pp60c-src. The results of our studies demonstrate that infection of mouse cells with wild-type polyoma virus or viral mutants capable of transforming rodent...

journal_title：Journal of cellular biochemistry

authors： Bolen JB,Lewis AM Jr,Israel MA

更新日期：1985-01-01 00:00:00

abstract：:The nuclear matrix (NM) contains a number of proteins that have been found to be associated with transformation. We have previously identified changes in the NM associated with prostate cancer. In this study, we examine the molecular changes that are associated with prostate cancer development in transgenic adenocarci...

journal_title：Journal of cellular biochemistry

authors： Leman ES,Arlotti JA,Dhir R,Greenberg N,Getzenberg RH

更新日期：2002-01-01 00:00:00

abstract：:Focal adhesion kinase (FAK) is a structurally unique nonreceptor protein-tyrosine kinase that localizes to focal adhesion plaques. Regulation of its activity has been implicated in diverse signaling pathways, including those mediated by extracellular matrix/integrin interactions, G-protein coupled receptors for mitoge...

journal_title：Journal of cellular biochemistry

authors： Polte TR,Naftilan AJ,Hanks SK

更新日期：1994-05-01 00:00:00

abstract：:The cardiomyocyte differentiation from mouse embryonic stem cells (mESCs) is a dynamic and complex process that involved in the precision regulation of histone acetylation. The formation of action potential (AP) in mature cardiomyocytes is based on the expression pattern of Na+ , Ca2+ , and K+ ion channels, in which t...

journal_title：Journal of cellular biochemistry

authors： Wang D,Liu C,Li Z,Wang Y,Wang W,Wu X,Wang K,Miao W,Li L,Peng L

更新日期：2017-12-01 00:00:00

abstract：:Dysregulation of lncRNAs is implicated in chemoresistance in varieties of tumor including acute myeloid leukemia (AML). LncRNA urothelial carcinoma-associated 1 (UCA1) was reported to play an oncogenic role in AML. However, whether UCA1 was involved in chemoresistance in pediatric AML remains unclear. UCA1 expression ...

journal_title：Journal of cellular biochemistry

authors： Zhang Y,Liu Y,Xu X

更新日期：2018-07-01 00:00:00

abstract：:The effects of serum on inositol 1,4,5-trisphosphate (IP3) formation and Ca2+ mobilization in the human submandibular cell line A253 were studied. Exposure of A253 cells to fetal bovine serum (FBS) elicited a 3.3-fold increase in IP3 formation and a concentration-dependent transient increase in cytosolic free Ca2+ con...

journal_title：Journal of cellular biochemistry

authors： Sun X,Mörk AC,Helmke RJ,Martinez JR,Zhang GH

更新日期：1999-06-15 00:00:00

abstract：:We have quantitatively measured gene expression for the sodium-dependent glucose cotransporters 1 and 2 (SGLT1 and SGLT2) in 23 human tissues using the method of real time PCR. As predicted, our results revealed that the expression of SGLT1 was very high in the small intestine (1.2E + 6 molecules/microg total RNA) rel...

journal_title：Journal of cellular biochemistry

authors： Zhou L,Cryan EV,D'Andrea MR,Belkowski S,Conway BR,Demarest KT

更新日期：2003-10-01 00:00:00

abstract：:Undecylenic acid (UDA), a naturally occurring 11-carbon unsaturated fatty acid, has been used for several years as an economical antifungal agent and a nutritional supplement. Recently, the potential usefulness of UDA as a neuroprotective drug has been suggested based on the ability of this agent to inhibit μ-calpain ...

journal_title：Journal of cellular biochemistry

authors： Jantas D,Piotrowski M,Lason W

更新日期：2015-12-01 00:00:00

abstract：:The regulatory role of regucalcin on cell responses for tumor necrosis factor-alpha (TNF-alpha) or transforming growth factor-beta1 (TGF-beta1) was investigated using the cloned normal rat kidney proximal tubular epithelial NRK52E cells overexpressing regucalcin. NRK52E cells (wild type) and stable regucalcin (RC)/pCX...

journal_title：Journal of cellular biochemistry

authors： Nakagawa T,Yamaguchi M

更新日期：2007-04-01 00:00:00

abstract：:Neurological disorders, such as stroke, are triggered by a loss of neurons and glial cells. Ischemic stroke remains a substantial problem for industrialized countries. Over the previous few decades our understanding about the pathophysiology of stroke has enhanced, nevertheless, more awareness is required to advance t...

journal_title：Journal of cellular biochemistry

authors： Rikhtegar R,Yousefi M,Dolati S,Kasmaei HD,Charsouei S,Nouri M,Shakouri SK

更新日期：2019-06-01 00:00:00

abstract：:Reactive oxygen species (ROS) were once viewed only as mediators of toxicity, but it is now recognized that they also contribute to redox signaling through oxidation of specific cysteine thiols on regulatory proteins. Cells in sparse cultures have increased ROS relative to confluent cultures, but it is not known wheth...

journal_title：Journal of cellular biochemistry

authors： Spielberger JC,Moody AD,Watson WH

更新日期：2008-08-01 00:00:00

abstract：:Angiotensin converting enzyme (ACE) 2 is a carboxypeptidase that shares 42% amino acid homology with ACE. Little is known about the regulation or pattern of expression of ACE2 in the mouse lung, including its definitive cellular distribution or developmental changes. Based on Northern blot and RT-PCR data, we report t...

journal_title：Journal of cellular biochemistry

authors： Wiener RS,Cao YX,Hinds A,Ramirez MI,Williams MC

更新日期：2007-08-01 00:00:00

abstract：:Although, the precise host defence mechanism(s) is not completely understood, T cell-mediated immune responses is believed to play a pivotal role in controlling parasite infection. Here we target the stage dependent over expressed gene. Here, the consensus based computational approach was adopted for the screening of ...

journal_title：Journal of cellular biochemistry

authors： Dikhit MR,Vijayamahantesh.,Kumar A,Amit A,Dehury B,Nathsharma YP,Ansari MY,Ali V,Topno RK,Das V,Pandey K,Sahoo GC,Bimal S,Das P

更新日期：2018-01-01 00:00:00

abstract：:Increasing evidence have proved that long noncoding RNAs (lncRNAs) play significant roles in tumorigenesis and development of various cancers. However, the effect of small nucleolar RNA host gene 20 (SNHG20) on the progression of esophageal squamous cell carcinoma (ESCC) remains to be discovered. Herein, we aim to fin...

journal_title：Journal of cellular biochemistry

authors： Zhang C,Jiang F,Su C,Xie P,Xu L

更新日期：2019-02-14 00:00:00

abstract：:Pancreatic adenocarcinomas induced in Syrian hamsters by treatment with N-nitrosobis(2-oxopropyl) amine express blood group A antigen, which is absent in normal pancreatic cells. On membrane glycoproteins purified from tumors, blood group A antigen has been found to be expressed on multiantennary Asn-linked complex gl...

journal_title：Journal of cellular biochemistry

authors： Hirota M,Mogaki M,Pour PM,Chaney WG

更新日期：1992-09-01 00:00:00

abstract：:Pancreatic ductal adenocarcinoma (PDAC) is an incidence rate nearly equal to its mortality rate. The poor prognosis of the disease can be explained by the absence of effective biomarkers for screening and early detection, together with the aggressive behavior and resistance to the currently available chemotherapy. The...

journal_title：Journal of cellular biochemistry

authors： Barati Bagherabad M,Afzaljavan F,ShahidSales S,Hassanian SM,Avan A

更新日期：2019-03-01 00:00:00

abstract：:In previous studies we have shown that all-trans retinoic acid (atRA)-treatment of the atRA-sensitive ovarian carcinoma cell line CA-OV3 repressed AP-1 activity by about 50%, while a similar effect was not observed in the atRA-resistant ovarian carcinoma cell line, SK-OV3. These results suggested that the repression o...

journal_title：Journal of cellular biochemistry

authors： Ramírez CJ,Haberbusch JM,Soprano DR,Soprano KJ

更新日期：2005-09-01 00:00:00

abstract：:HOXB13 exerts a close relation in several human cancers. This study explored the role of HOXB13 in glioblastoma (GBM), a brain tissue with the highest aggressive rate and mortality in adults. Through microarray and immunohistochemistry analyses, HOXB13 was highly expressed in GBM tissues. Furthermore, we showed that h...

journal_title：Journal of cellular biochemistry

authors： Wang X,Sun Y,Xu T,Qian K,Huang B,Zhang K,Song Z,Qian T,Shi J,Li L

更新日期：2019-09-01 00:00:00

abstract：:Mechanotransduction is a key process by which cells perceive extracellular mechanical cues/intercellular physical interactions and transform them into intracellular biochemical signals. This physiological process is crucial during bone development and bone remodeling throughout childhood and adult life, whereas severa...

journal_title：Journal of cellular biochemistry

authors： Adamopoulos C,Gargalionis AN,Piperi C,Papavassiliou AG

更新日期：2017-02-01 00:00:00

abstract：:Myelin basic protein (MBP) is a major component of the myelin sheath whose production is developmentally controlled during myelinogenesis. Earlier studies have indicated that programmed expression of the MBP gene is regulated at the level of transcription. Evidently, the MB1 regulatory motif located between nucleotide...

journal_title：Journal of cellular biochemistry

authors： Muralidharan V,Tretiakova A,Steplewski A,Haas S,Amini S,Johnson E,Khalili K

更新日期：1997-09-15 00:00:00

abstract：:Long non-coding RNAs (lncRNAs) can participate in the pathological process of multiple myeloma (MM) via regulation of specific gene expression and function. This research aimed to study the role of MALAT-1 and the underlying mechanism in MM. In this study, the expression of MALAT-1 and HMGB1 protein in the bone marrow...

journal_title：Journal of cellular biochemistry

authors： Gao D,Lv AE,Li HP,Han DH,Zhang YP

更新日期：2017-10-01 00:00:00

abstract：:We have previously demonstrated that the ultraviolet (UV) light is effective against a variety of cancer cells in vivo as well as in vitro. In the present report, we imaged the DNA damage repair response of minimal cancer after UVC irradiation. DNA-damage repair response to UV irradiation was imaged on tumors growing ...

journal_title：Journal of cellular biochemistry

authors： Miwa S,Yano S,Hiroshima Y,Tome Y,Uehara F,Mii S,Efimova EV,Kimura H,Hayashi K,Tsuchiya H,Hoffman RM

更新日期：2013-11-01 00:00:00

abstract：:Hamster embryo cells metabolize benzo(a)pyrene to derivatives that covalently modify the nuclear macromolecules including proteins. Not all proteins are modified to the same extent nor by the same metabolites. In particular, a protein of apparent molecular weight 32,000 is highly modified by derivatives of trans-9,10-...

journal_title：Journal of cellular biochemistry

authors： MacLeod MC,Mansfield BK,Selkirk JK

更新日期：1982-01-01 00:00:00

abstract：:The differentiation therapy in treatment of acute promyelocytic leukemia (APL), based on the administration of all-trans retinoic acid (ATRA), is currently flanked with the use of As2O3, a safe and effective agent for patients showing a resistance to ATRA treatment. A synergy between ATRA and As3O3 was also reported i...

journal_title：Journal of cellular biochemistry

authors： Brugnoli F,Bovolenta M,Benedusi M,Miscia S,Capitani S,Bertagnolo V

更新日期：2006-05-01 00:00:00