Founder of modern hydrocephalus diagnosis and therapy: Walter Dandy at the Johns Hopkins Hospital.


:Because of his exceptional and pioneering contributions to the understanding and treatment of neurosurgical conditions, Walter Dandy is considered to be one of the founders of both neurosurgery and neuroradiology. In the field of hydrocephalus, Dandy developed revolutionary research models, imaging modalities, and operative procedures. His laboratory and clinical experiences at the Johns Hopkins Hospital, including the surgical treatment of hydrocephalus, are well illustrated in the publications he authored. Archival materials housed at the Johns Hopkins University School of Medicine provide a window into Dandy's clinical experience and supplement the work published during his lifetime. His operative experience with hydrocephalus spanned 1915-1946 and comprised 381 surgeries. From this clinical experience, Dandy created much of the framework for modern diagnostic imaging and treatment of hydrocephalus.


J Neurosurg


Journal of neurosurgery


Blitz AM,Ahmed AK,Rigamonti D




Has Abstract


2018-10-01 00:00:00










  • Treatment of autochthonous rat brain tumors with fractionated radiotherapy. The effects of graded radiation doses and of combined therapy with BCNU or steroids.

    abstract::The avian sarcoma virus-induced glioma model in rats was used to evaluate radiation dose response (survival curves), giving fractionated treatments to the whole head. Groups of 14 to 20 rats received total doses of 2300, 4600, or 5750 rads over 2, 4, or 5 weeks, respectively. Median group survival times were compared ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Steinbok P,Mahaley MS Jr,U R,Varia MA,Lipper S,Mahaley J,Dalzell JG,Bigner DD

    更新日期:1980-07-01 00:00:00

  • Effects of anesthesia and laminectomy on regional spinal cord blood flow in conscious sheep.

    abstract::Blood flow for the whole spinal cord (SCBF), central cord (largely gray matter), and peripheral cord (largely white matter) has been measured at all segmental levels using radioactive microspheres in conscious sheep. Whole SCBF was greatest in the lower cervical and lumbar enlargements and least in the upper cervical ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Hales JR,Yeo JD,Stabback S,Fawcett AA,Kearns R

    更新日期:1981-05-01 00:00:00

  • Intracranial pressure in nontraumatic ischemic and hypoxic cerebral insults.

    abstract::Intracranial pressure (ICP) and cerebral perfusion pressure were monitored in 12 patients who were comatose secondary to hypoxic (five cases) or hypotensive (seven cases) nontraumatic cerebral insults. Patients who were hypotensive but not hypoxic developed significant increased ICP. In patients who were comatose from...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Senter HJ,Wolf A,Wagner FC Jr

    更新日期:1981-04-01 00:00:00

  • Management and outcome of hemorrhage after Gamma Knife surgery for arteriovenous malformations of the brain.

    abstract:OBJECT:Appropriate management of hemorrhage after Gamma Knife surgery (GKS) for arteriovenous malformations (AVMs) of the brain is poorly understood, although a certain proportion of patients suffer from hemorrhage. METHODS:Among 500 patients observed for 1 to 183 months (median 70 months) after GKS, 32 patients (6.4%...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Maruyama K,Shin M,Tago M,Kurita H,Kawahara N,Morita A,Saito N

    更新日期:2006-12-01 00:00:00

  • Prognostic factors in the persistence of posttraumatic epilepsy after penetrating head injuries sustained in war.

    abstract:OBJECT:The goal of this paper was to investigate the long-term outcome and the possible prognostic factors that might have influenced the persistence of posttraumatic epilepsy after penetrating head injuries sustained during the Iraq-Iran war (1980-1988). METHODS:In this retrospective study, the authors evaluated 189 ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Eftekhar B,Sahraian MA,Nouralishahi B,Khaji A,Vahabi Z,Ghodsi M,Araghizadeh H,Soroush MR,Esmaeili SK,Masoumi M

    更新日期:2009-02-01 00:00:00

  • Late recovery following spinal cord injury. Case report and review of the literature.

    abstract::The authors of this prospective, single-case study evaluated the potential for functional recovery from chronic spinal cord injury (SCI). The patient was motor complete with minimal and transient sensory perception in the left hemibody. His condition was classified as C-2 American Spinal Injury Association (ASIA) Grad...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: McDonald JW,Becker D,Sadowsky CL,Jane JA Sr,Conturo TE,Schultz LM

    更新日期:2002-09-01 00:00:00

  • The effect of single-application topical ophthalmic anesthesia in patients with trigeminal neuralgia. A randomized double-blind placebo-controlled trial.

    abstract::To evaluate the reported benefit of ipsilateral single-application ophthalmic anesthetic eyedrops in patients with typical trigeminal neuralgia, a randomized double-blind placebo-controlled trial was performed. Forty-seven patients were randomly assigned to receive two drops of either proparacaine (25 cases) or saline...

    journal_title:Journal of neurosurgery

    pub_type: 临床试验,杂志文章,随机对照试验


    authors: Kondziolka D,Lemley T,Kestle JR,Lunsford LD,Fromm GH,Jannetta PJ

    更新日期:1994-06-01 00:00:00

  • Central nervous system leiomyosarcoma in patients with acquired immunodeficiency syndrome. Report of two cases.

    abstract::Leiomyosarcomas (LMSs) of the central nervous system are extremely rare; however, they are becoming more prevalent in immunocompromised patients. The authors present the cases of two patients with acquired immunodeficiency syndrome: one with LMS of the thoracic vertebral body and the other with LMS originating from th...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Ritter AM,Amaker BH,Graham RS,Broaddus WC,Ward JD

    更新日期:2000-04-01 00:00:00

  • Intradural extramedullary tuberculoma of the cervical spine. Case report.

    abstract::A case is reported of a 45-year-old man who developed quadriplegia following a trivial motor-vehicle accident. Investigation including computerized tomography (CT) of the cervical spine revealed a large calcified lesion displacing the spinal cord and nerve roots, which proved to be a tuberculoma. The case is unusual i...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Compton JS,Dorsch NW

    更新日期:1984-01-01 00:00:00

  • Intravertebral vacuum phenomenon in osteoporotic compression fracture: report of 67 cases with quantitative evaluation of intravertebral instability.

    abstract:OBJECT:The objectives of this study were to: 1) describe the incidence and clinical features of intravertebral vacuum phenomenon (IVVP) in a relatively large number of cases; 2) quantitatively evaluate intravertebral instability and determine the factors affecting instability; and 3) evaluate the efficacy of percutaneo...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Kim DY,Lee SH,Jang JS,Chung SK,Lee HY

    更新日期:2004-01-01 00:00:00

  • Pituitary gland metastasis from adenocarcinoma of the prostate. Case report.

    abstract::A case of prostatic carcinoma metastasis to the pituitary gland is reported. The presentation and rarity of such a lesion is addressed. The literature review yielded only isolated case reports of symptomatic brain metastases unassociated with bone disease from adenocarcinoma of the prostate. The management options of ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审


    authors: Couldwell WT,Chandrasoma PT,Weiss MH

    更新日期:1989-07-01 00:00:00

  • Resection and brain brachytherapy with permanent iodine-125 sources for brain metastasis.

    abstract::OBJECTIVE Stereotactic radiosurgery (SRS) with or without whole-brain radiotherapy can be used to achieve local control (> 90%) for small brain metastases after resection. However, many brain metastases are unsuitable for SRS because of their size or previous treatment, and whole-brain radiotherapy is associated with ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Raleigh DR,Seymour ZA,Tomlin B,Theodosopoulos PV,Berger MS,Aghi MK,Geneser SE,Krishnamurthy D,Fogh SE,Sneed PK,McDermott MW

    更新日期:2017-06-01 00:00:00

  • Transoral, transsphenoidal microsurgical exposure of the pituitary gland and infundibulum in the rhesus monkey. Description of operative technique.

    abstract::A transoral, transsphenoidal microsurgical technique for exposing the pituitary stalk and gland of the rhesus monkey is described and illustrated. The technique has proved to be a safe and practical method for performing a variety of pituitary operations in a total of 37 animals. The procedures have included complete ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Tindall GT,Patton J,Neill JD

    更新日期:1977-11-01 00:00:00

  • Moyamoya disease in monovular twins: case report.

    abstract::The first reported instance of identical twins with moyamoya disease is presented. The involved portions of the main intracranial arteries were similar, but the formation of the moyamoya vessels was somewhat different. The cause fo obstructive changes in large intracranial arteries remains obscure, but the frequent fa...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Yamada H,Nakamura S,Kageyama N

    更新日期:1980-07-01 00:00:00

  • Angiographic frequency of saccular intracranial aneurysms in patients with spontaneous cervical artery dissection.

    abstract::The pathogenesis of intracranial aneurysms and spontaneous cervical artery dissection is incompletely understood but a primary arteriopathy, possibly similar in both disorders, may be of importance. To investigate the frequency of intracranial aneurysms in patients with spontaneous cervical artery dissection, the angi...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Schievink WI,Mokri B,Piepgras DG

    更新日期:1992-01-01 00:00:00

  • Efficacy of and morbidity associated with stereoelectroencephalography using computerized tomography--or magnetic resonance imaging-guided electrode implantation.

    abstract:OBJECT:The purpose of this paper was to define the general efficacy of and morbidity associated with stereoelectroencephalography using modem methods of imaging and to particularize the risks related to specific lobes of the brain. METHODS:All patients admitted to the Montreal Neurological Institute who had undergone ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: De Almeida AN,Olivier A,Quesney F,Dubeau F,Savard G,Andermann F

    更新日期:2006-04-01 00:00:00

  • Hemifacial spasm caused by a spontaneous dissecting aneurysm of the vertebral artery. Case report.

    abstract::The authors describe the first reported case of dissecting aneurysm presenting with hemifacial spasm. The patient was a 58-year-old woman with left hemifacial spasm of 2 years' duration. Cranial nerve examination was otherwise normal and no other clinical symptoms were observed. Vertebral angiography revealed a fusifo...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Matsumoto K,Saijo T,Kuyama H,Asari S,Nishimoto A

    更新日期:1991-04-01 00:00:00

  • Cost analysis of awake versus asleep deep brain stimulation: a single academic health center experience.

    abstract::OBJECT The objective of this study was to compare the cost of deep brain stimulation (DBS) performed awake versus asleep at a single US academic health center and to compare costs across the University HealthSystem Consortium (UHC) Clinical Database. METHODS Inpatient and outpatient demographic and hospital financial ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Jacob RL,Geddes J,McCartney S,Burchiel KJ

    更新日期:2016-05-01 00:00:00

  • Relationship of acute CBF and ICP findings to neuropsychological outcome in severe head injury.

    abstract::Neuropsychological outcome within 1 year after severe head injury was examined in 42 conscious survivors and correlated with acute measurements of cerebral blood flow (CBF) and intracranial pressure (ICP). During acute coma, CBF was elevated in 23 patients, indicating hyperemia, and was reduced in the remaining 19 cas...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Uzzell BP,Obrist WD,Dolinskas CA,Langfitt TW

    更新日期:1986-11-01 00:00:00

  • Elucidating the kinetics of sodium fluorescein for fluorescence-guided surgery of glioma.

    abstract:OBJECTIVE:The use of the optical contrast agent sodium fluorescein (NaFl) to guide resection of gliomas has been under investigation for decades. Although this imaging strategy assumes the agent remains confined to the vasculature except in regions of blood-brain barrier (BBB) disruption, clinical studies have reported...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Folaron M,Strawbridge R,Samkoe KS,Filan C,Roberts DW,Davis SC

    更新日期:2018-09-07 00:00:00

  • Morphological studies of human arteriovenous malformations. Effects of isobutyl 2-cyanoacrylate embolization.

    abstract::Ten patients with symptomatic arteriovenous malformations (AVM's) underwent embolization with isobutyl 2-cyanoacrylate (Bucrylate) delivered via a mini-balloon catheter according to the protocol of George and Pevsner. These patients underwent surgical removal of their embolized AVM, and surgical specimens were evaluat...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Klara PM,George ED,McDonnell DE,Pevsner PH

    更新日期:1985-09-01 00:00:00

  • Clinical characteristics of arteriovenous malformations in the cerebellopontine angle cistern.

    abstract::OBJECTIVE Arteriovenous malformations (AVMs) in the cerebellopontine angle cistern (CPAC) are specific lesions that can cause neurovascular compression syndromes as well as intracranial hemorrhage. Although case reports describing the CPAC AVMs, especially those presenting with trigeminal neuralgia (TN), have been acc...

    journal_title:Journal of neurosurgery

    pub_type: 评论,杂志文章


    authors: Nishino K,Hasegawa H,Morita K,Fukuda M,Ito Y,Fujii Y,Sato M

    更新日期:2017-01-01 00:00:00

  • Stereotaxic reconstruction of the aqueduct of Sylvius.

    abstract::A stereotaxic technique has been developed to cannulate the cerebral aqueduct in patients with hydrocephalus resulting from occlusion of the aqueduct of Sylvius. Precise placement of a 15- to 20-mm long radiopaque prosthesis between the third and fourth ventricles can reestablish the normal cerebrospinal fluid (CSF) p...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Backlund EO,Grepe A,Lunsford D

    更新日期:1981-11-01 00:00:00

  • Neuroendoscopic fenestration of glioependymal cysts to the ventricle: report of 3 cases.

    abstract::Glioependymal cysts are rare congenital lesions of the central nervous system. Reported surgical treatments of these lesions have varied and yielded mixed results, and the optimal surgical strategy is still controversial. The authors here report the clinical and surgical outcomes for three adult patients successfully ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Alvarado AM,Smith KA,Chamoun RB

    更新日期:2018-11-01 00:00:00

  • Carotid body tumors managed with preoperative embolization. Report of two cases.

    abstract::Two patients with large vascular carotid body tumors underwent preoperative intravascular embolization of the major arterial feeders. The tumor vascularity was reduced markedly, and complete surgical extirpation was accomplished without difficulty. The literature on carotid body tumors is briefly reviewed. The role of...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Borges LF,Heros RC,DeBrun G

    更新日期:1983-11-01 00:00:00

  • Eosinophilic granuloma of the cervicothoracic junction. Case report.

    abstract::A case is reported of eosinophilic granuloma at the cervicothoracic junction presenting with profound quadriparesis preoperatively. The patient underwent excision via an anterior approach, with splitting of the sternum to gain access to the T-1 vertebra. Postoperatively, he has had an excellent return of function. ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章,评审


    authors: Sweasey TA,Dauser RC

    更新日期:1989-12-01 00:00:00

  • Early and late epilepsy surgery in focal epilepsies associated with long-term epilepsy-associated tumors.

    abstract::OBJECTIVE Epilepsy surgery is an effective means of treating focal epilepsy associated with long-term epilepsy-associated tumors. This study evaluated a large population of surgically treated patients with childhood onset of epilepsy and a histologically confirmed diagnosis of long-term epilepsy-associated tumors. The...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Pelliccia V,Deleo F,Gozzo F,Sartori I,Mai R,Cossu M,Tassi L

    更新日期:2017-11-01 00:00:00

  • Dystonic tics induced by deep brain stimulation of the posterior subthalamic area for essential tremor.

    abstract::OBJECTIVE The posterior subthalamic area (PSA) is a promising target of deep brain stimulation (DBS) for medication-refractory essential tremor (ET). This case series describes a novel adverse effect manifesting as dystonic tics in patients with ET undergoing DBS of the PSA. METHODS Six patients with ET received elect...

    journal_title:Journal of neurosurgery

    pub_type: 评论,杂志文章


    authors: Chandran AS,Joshi S,Thorburn M,Stell R,Lind CR

    更新日期:2017-02-01 00:00:00

  • CSF smooth-muscle constrictor activity associated with cerebral vasospasm and mortality in SAH patients.

    abstract::Cerebrospinal fluid (CSF) was collected preoperatively (by lumbar puncture) or perioperatively (by lumbar or ventricular drain) from 32 patients with subarachnoid hemorrhage (SAH) from ruptured intracranial aneurysms. Samples were also obtained from six control patients without evidence of subarachnoid blood. Smooth-m...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Kaye AH,Tagari PC,Teddy PJ,Adams CB,Blaso WP,Boullin DJ

    更新日期:1984-05-01 00:00:00

  • Cavernous angioma of the geniculate ganglion.

    abstract::Intracranial extraaxial cavernous angiomas are rare vascular malformations. Their occurrence at the geniculate ganglion of the facial nerve within the temporal bone is exceptional. The authors describe a 35-year-old man who developed a slowly progressing facial palsy. Initial cranial MR imaging showed no pathological ...

    journal_title:Journal of neurosurgery

    pub_type: 杂志文章


    authors: Capelle HH,Nakamura M,Lenarz T,Brandis A,Haubitz B,Krauss JK

    更新日期:2008-11-01 00:00:00