Dose responses of cerebral arteries of the dog, rabbit, and man to human hemoglobin in vitro.

Abstract:

:Dose responses in vitro of the basilar arteries of the dog, rabbit, and man to human hemoglobin and reported. For each species, the response occurred over a range of 10(-9)M to greater than 10(-5)M hemoglobin. When compared to a maximum serotonin contraction, the relative constriction induced by 10(-5)M hemoglobin was greater in the rabbit than in the dog, which in turn was greater than in man. The comparatively weak response of the human arteries is probably attributable to postmortem changes.

journal_name

J Neurosurg

journal_title

Journal of neurosurgery

authors

Wellum GR,Irvine TW Jr,Zervas NT

doi

10.3171/jns.1980.53.4.0486

subject

Has Abstract

pub_date

1980-10-01 00:00:00

pages

486-90

issue

4

eissn

0022-3085

issn

1933-0693

journal_volume

53

pub_type

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