Abstract:
:The International Continence Society (ICS) has sustained a drive to improve the clinical assessment of lower urinary tract function for many years. Increasingly, healthcare professionals (HCPs) engage with the guidance, and patients benefit from the precision that results when their carers apply a sensible and logical approach to assessment. The current supplementary issue of Neurourology and Urodynamics (NAU) summarizes the fundamentals derived from major ICS initiatives, emphasizing what HCPs must know when dealing with these patients, regardless of the medical discipline in which they work. It also introduces the basics of urodynamics testing to trainees and HCPs who may refer patients for testing. In this editorial review we draw out some additional points of consideration. We emphasize the need to avoid using terms in a clinical context that could imply causative mechanism, until the mechanism has actually been identified. We caution against the use of severity thresholds, until there is proper data to justify their application for any given patient group. Finally, we provide a description of the philosophical basis of urodynamics testing, including videourodynamics. This commentary should be read in the context of the other articles provided in the NAU supplement.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
Drake MJ,Abrams Pdoi
10.1002/nau.23732subject
Has Abstractpub_date
2018-08-01 00:00:00pages
S7-S12issue
S6eissn
0733-2467issn
1520-6777journal_volume
37pub_type
杂志文章abstract:AIM:The maximum urethral closure pressure (MUCPs) and functional urethral length (FUL) obtained with water-filled and air-charged catheters during urethral pressure profile (UPP) determination was compared in a single, blind, randomized, and prospective trial. METHODS:Thirty-three males with spinal cord injuries and n...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.24071
更新日期:2019-08-01 00:00:00
abstract:AIMS:To investigate the effect of the bladder sensation grade on uroflowmetry parameters. METHODS:Fifty healthy volunteering young men were enrolled in the present study. In total, three uroflowmetry evaluations were made. Qmax , Qave , VV, and PVR urine was obtained three times in three described bladder sensation gr...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22762
更新日期:2016-06-01 00:00:00
abstract:AIMS:We determined if THC-002, a galenical produced from Ba-Wei-Die-Huang-Wan, could increase skin temperature and inhibit detrusor overactivity induced by sudden whole body cooling. Further, we determined if THC-002 could decrease expression of transient receptor potential melastatin 8 (TRPM8) channels associated with...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22335
更新日期:2013-06-01 00:00:00
abstract:AIMS:The aim of our study was to access the variability of maximum flow rate (Q(max)), average flow rate (Q(av)) and flow pattern while varying the point of impact of flow on the flowmeter. METHODS:Water was delivered through a motorised tube holder in a standardised experimental set up. Flow was directed in 4 differe...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20846
更新日期:2010-09-01 00:00:00
abstract::This study investigated the effects of outlet obstruction on blood flow and high energy phosphates content in the rabbit urinary bladder. Mild bladder outlet obstruction was induced by placing a silicon ring (diameter 7 mm) around the bladder neck of each male New Zealand White rabbit (n = 7). Before and immediately a...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930140309
更新日期:1995-01-01 00:00:00
abstract:OBJECTIVES:We evaluated the association between lower urinary tract symptoms (LUTS) and the expression of connexin (Cx) and transient receptor potential (TRP) channel on urothelial cells non-invasively collected from voided urine in humans. METHODS:A total of 55 patients (36 males and 19 females, median age: 71 years ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23436
更新日期:2018-03-01 00:00:00
abstract:AIMS:To examine early trends in the use of overactive bladder (OAB) agents across Canada, with a focus on initial uptake and reimbursement of two newer agents: fesoterodine, an anticholinergic, and mirabegron, a therapeutically novel beta-3 agonist. METHODS:We conducted a population-based cross-sectional study of outp...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23469
更新日期:2018-06-01 00:00:00
abstract:AIMS:To identify clinical and urodynamic factors leading to spontaneous voiding in men with detrusor underactivity (DU) and suspected bladder outlet obstruction who underwent an outlet de-obstruction procedure. METHODS:We identified 614 men who underwent an outlet procedure at our institution from 2005 to 2014. Men we...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24122
更新日期:2019-11-01 00:00:00
abstract:AIM:To determine the optimal degree of pubovaginal slings (PVS) tension, measured by lax sling dimensions to minimize the risk of urinary retention. METHODS:This prospective study analyzed female patients undergoing PVS for stress urinary incontinence (SUI) by two surgeons over 24 months from January 2016. Intra-opera...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24000
更新日期:2019-06-01 00:00:00
abstract::Patients with symptoms of overactive bladder syndrome or non-obstructive urinary retention, refractory to conservative therapy, can nowadays be treated minimally invasively with sacral nerve stimulation (SNS). The use of electric currents to treat urological pathology has a long history but SNS therapy only received F...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.20459
更新日期:2008-01-01 00:00:00
abstract::Experiments to investigate restoration of lower urinary tract control by electrical stimulation of the sacral nerve roots are mostly performed on dogs, yet little morphometric data (such as canine root and fiber diameter distributions) are available. The aim of this study was to acquire morphometric data of the intrad...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(SICI)1520-6777(1996)15:3<235::AID-NAU8>3.
更新日期:1996-01-01 00:00:00
abstract:AIMS:Urinary tract infection (UTI) is a common complication after pelvic floor surgery. Antibiotics as prophylaxis may reduce the prevalence of UTI's by 50%, but bacterial resistance may be a large disadvantage, necessitating the search for other possible prophylactic options. Recent research found a 50% reduction in t...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.24391
更新日期:2020-06-01 00:00:00
abstract:AIMS:Reflex bladder activation and inhibition by electrical stimulation of pudendal nerve (PN) afferents is a promising approach to restore control of bladder function in persons with lower urinary tract dysfunction caused by disease or injury. The objective of this work was to determine whether bladder activation evok...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22822
更新日期:2016-11-01 00:00:00
abstract:AIMS:To evaluate if pelvic floor innervation differed in patients with rectocele compared to control subjects and to assess if nerve fiber density of the rectovaginal wall correlated to the clinical presentation of rectocele. METHODS:Biopsies from 24 female patients with posterior vaginal wall prolapse stage II (ICS-c...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20249
更新日期:2006-01-01 00:00:00
abstract:INTRODUCTION:Overactive bladder syndrome (OAB) including urgency and urgency urinary incontinence (UUI) occurs frequently after stress urinary incontinence (SUI) surgery. It is important to identify the risk factors for the occurrence of OAB symptoms in order to adequately inform the patient before surgery. Furthermore...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.23328
更新日期:2018-01-01 00:00:00
abstract::The mammalian TRP family consists of 28 channels that can be subdivided into 6 different classes: TRPV (vanilloid), TRPC (canonical), TRPM (Melastatin), TRPP (Polycystin), TRPML (Mucolipin), and TRPA (Ankyrin). TRP channels are activated by a diversity of physical (voltage, heat, cold, mechanical stress) or chemical (...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.20511
更新日期:2008-01-01 00:00:00
abstract:AIMS:The prevalence rate of severe fecal incontinence (FI) in adults with spina bifida (SB) is high. The physiological basis of FI in SB has not been clearly established, which contributes to inadequate care. The aim was to better characterize a large cohort of adults with special consideration of anorectal physiology....
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23417
更新日期:2018-03-01 00:00:00
abstract::Better understanding of the underlying working mechanism of the neural control of the lower urinary tract will facilitate the treatment of dysfunction with a neurogenic cause. We developed a computer model to study the effect of a neural control system on lower urinary tract behavior. To model the mechanical propertie...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/(sici)1520-6777(1998)17:3<175::aid-nau3>3.
更新日期:1998-01-01 00:00:00
abstract:AIMS:The fall rate in urgency urinary incontinence (UUI) and mixed UI (MUI) older women is higher when compared with that of continent women. One hypothesis is that a strong desire to void (SDV) could alter gait parameters and therefore increase the risk of falls. The aim of this study was to investigate and compare th...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24234
更新日期:2020-02-01 00:00:00
abstract:AIMS:Our objective was to determine what women find acceptable regarding treatment and outcomes for treatment of stress urinary incontinence (SUI), and correlate this to age, distress and quality of life (QOL). MATERIALS AND METHODS:This prospective cross-sectional IRB-approved study evaluated women with primary SUI. ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20570
更新日期:2008-01-01 00:00:00
abstract:AIMS:Intrinsic sphincteric deficiency (ISD) denotes a malfunction of the distal urethral sphincter. Our objective was to produce a durable model of ISD in the rat. METHODS:Surrounding tissues lateral to the mid-urethra were cauterized to produce sphincteric injury in 24 adult female Sprague-Dawley rats. The rats were ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10173
更新日期:2004-01-01 00:00:00
abstract:AIMS:To evaluate the functional and molecular alterations of contractile and relaxant machinery in the bladder and urethra that lead to the underactive bladder (UAB) in old female mice. METHODS:Female young (3-months) and old (18-months) C57BL/6 mice were used. Urodynamic was assessed in awake and anaesthetized mice. ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23990
更新日期:2019-06-01 00:00:00
abstract:AIMS:The purpose of this scoping review was to examine research activity comparing suprapubic catheterization to any other method of chronic bladder emptying such as intermittent and indwelling catheterization in adults in relation to complications, patient satisfaction, and health-related quality of life (QoL). METHO...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.22356
更新日期:2013-09-01 00:00:00
abstract:AIMS:Succinate and its receptor, GPR91, have been implicated in different aspects of metabolic syndrome. As GPR91 is expressed in the urinary bladder, the aim of this study is to show the effect of chronically increased succinate levels on bladder function. MATERIALS AND METHODS:Healthy Sprague-Dawley (SD) rats and hy...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23488
更新日期:2018-06-01 00:00:00
abstract:AIMS:Pelvic organ prolapse occurs in 50% of parous women. Laparoscopic sacrocolpopexy (LSCP) is a common surgical procedure for restoring pelvic anatomy and function. The aim of this study is to evaluate surgical anatomy and anatomical modifications induced by standardized LSCP. METHODS:Ten fresh female cadavers under...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22806
更新日期:2016-09-01 00:00:00
abstract:AIMS:This study investigated the expressions of PGP9.5, P2 X 3 , muscarinic receptor (M3) and beta-3 adrenoreceptor (AR) in idiopathic detrusor overactivity (IDO) patients refractory to antimuscarinic treatment, and analyzed the correlation between protein expressions and clinical symptoms of IDO bladders with differe...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23138
更新日期:2017-06-01 00:00:00
abstract:AIMS:To investigate relationships between pelvic floor muscles (PFM) and sexual function (SF) in sexually active (SA) and not-SA (NSA) women with pelvic floor disorders (PFD). METHODS:In 350 women with PFD: 173 (49.4%) SA, 177 (50.6%) NSA, Pelvic Organ Prolapse (POP)-Quantification, PFM tone, and strength were evaluat...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24109
更新日期:2019-09-01 00:00:00
abstract:OBJECTIVES:To create an animal model for neurogenic underactive bladder disease (UAB) and identify markers to describe secondary myogenic changes in the bladder wall. MATERIALS AND METHODS:Male rats underwent either bilateral pelvic nerve injury or sham surgery. Four weeks after surgery functional evaluation was perfo...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23517
更新日期:2018-06-01 00:00:00
abstract:AIMS:P(2)X(3) (ATP-gated receptors) in nociceptive neurons of dorsal root ganglion (DRG) participate in transmission of pain signals from the periphery to the spinal cord. However, the role of P(2)X(3) receptors in chronic prostate pain and continued intractable pain remains unclear. MATERIALS AND METHODS:We examined ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.21060
更新日期:2011-04-01 00:00:00
abstract:AIMS:To determine the distributions of bothersome and non-bothersome nocturnal voiding and the differences between them using a community-based study. SUBJECTS AND METHODS:A total of 2,205 men and women aged 41-70 years from three Japanese towns responded to our postal questionnaire survey. The questionnaire included ...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20451
更新日期:2007-01-01 00:00:00