Abstract:
:Better understanding of the underlying working mechanism of the neural control of the lower urinary tract will facilitate the treatment of dysfunction with a neurogenic cause. We developed a computer model to study the effect of a neural control system on lower urinary tract behavior. To model the mechanical properties and neural control, assumptions had to be made. These assumptions were based, as much as possible, on knowledge and hypotheses taken from the literature. With valid assumptions, it should be possible to simulate normal as well as pathological behavior. To test the computer model, first, normal behavior of the lower urinary tract was simulated, and secondly, the known features of bladder outlet obstruction were simulated after the properties of the urethra were changed. The simulation results are comparable with measured data, so the assumptions on which the model is based could be valid. If the assumptions are valid, the feedback loops used in the model are also important feedback loops in vivo, and the model can be used to gain insight into the underlying mechanism of neural control.
journal_name
Neurourol Urodynjournal_title
Neurourology and urodynamicsauthors
van Duin F,Rosier PF,Rijkhoff NJ,van Kerrebroek PE,Debruyne FM,Wijkstra Hdoi
10.1002/(sici)1520-6777(1998)17:3<175::aid-nau3>3.subject
Has Abstractpub_date
1998-01-01 00:00:00pages
175-96issue
3eissn
0733-2467issn
1520-6777pii
10.1002/(SICI)1520-6777(1998)17:3<175::AID-NAU3>3.journal_volume
17pub_type
杂志文章abstract:AIMS:To determine the antiseptic efficacy on bacterial colony counts of a 5- vs 10-minute surgical site scrub in urologic surgery. METHODS:A prospective cohort study was conducted in 101 patients presenting for elective urological procedures. Patients were randomized to a 5- or 10-minute groin scrub with Betadine (pov...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.23945
更新日期:2019-03-01 00:00:00
abstract:AIM OF THE STUDY:To estimate the prevalence and 5-year incidence of lower urinary tract symptoms (LUTS) after the first delivery and to evaluate the impact of pregnancy per se and delivery per se on long-lasting symptoms. MATERIALS AND METHODS:A longitudinal cohort study of 305 primiparae questioned a few days, 3 mont...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.2198
更新日期:2002-01-01 00:00:00
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journal_title:Neurourology and urodynamics
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更新日期:2020-03-01 00:00:00
abstract::This is the first report of the International Continence Society (ICS) on the development of comprehensive guidelines for Good Urodynamic Practice for the measurement, quality control, and documentation of urodynamic investigations in both clinical and research environments. This report focuses on the most common urod...
journal_title:Neurourology and urodynamics
pub_type: 指南,杂志文章,实务指引
doi:10.1002/nau.10066
更新日期:2002-01-01 00:00:00
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journal_title:Neurourology and urodynamics
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pub_type: 杂志文章
doi:10.1002/nau.22245
更新日期:2012-11-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
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更新日期:2019-08-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.22787
更新日期:2016-08-01 00:00:00
abstract::Investigations of micromotion characteristics of bladder wall strips and pressure wave phenomena in total bladders in vitro and in vivo indicate that micromotion phenomena occur in the bladder wall. Local contractions can occur without an increase in tension or pressure, because other parts are in antiphase. Local con...
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pub_type: 杂志文章
doi:10.1002/nau.1930120504
更新日期:1993-01-01 00:00:00
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pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,评审
doi:10.1002/nau.21097
更新日期:2011-06-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/nau.22208
更新日期:2012-09-01 00:00:00
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pub_type: 杂志文章
doi:10.1002/nau.22335
更新日期:2013-06-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.1930120311
更新日期:1993-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20123
更新日期:2006-01-01 00:00:00
abstract:AIM:To determine the importance and contribution of compliance in a pelvic muscle exercise program as a factor in reducing the severity of urinary stress incontinence amongst Chinese women. METHODS:Two hundred fourteen women presenting with urinary stress incontinence who agreed to undertake a program of pelvic muscle...
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pub_type: 临床试验,杂志文章
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更新日期:2003-01-01 00:00:00
abstract:AIMS:The aim of this study was to evaluate the effect of automatic event driven electrical stimulation on the dorsal penile/clitoral nerve for management of neurogenic detrusor overactivity in patients suffering from Multiple Sclerosis. METHODS:A total of 10 patients participated in the study. Detrusor pressure was re...
journal_title:Neurourology and urodynamics
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.22952
更新日期:2017-02-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20522
更新日期:2008-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.24349
更新日期:2020-06-01 00:00:00
abstract:AIM:The maximum urethral closure pressure (MUCPs) and functional urethral length (FUL) obtained with water-filled and air-charged catheters during urethral pressure profile (UPP) determination was compared in a single, blind, randomized, and prospective trial. METHODS:Thirty-three males with spinal cord injuries and n...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.24071
更新日期:2019-08-01 00:00:00
abstract::Hypoxia induced by partial outlet obstruction is believed to play a major role in both the hypertrophic and degenerative effects of partial outlet obstruction. Doxazosin (dox) is a clinically effective alpha-adrenergic antagonist used in the treatment of symptomatic benign prostatic hyperplasia (BPH). Although the maj...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.10045
更新日期:2002-01-01 00:00:00
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journal_title:Neurourology and urodynamics
pub_type: 杂志文章,meta分析
doi:10.1002/nau.20243
更新日期:2006-01-01 00:00:00
abstract:AIMS:Prostate cancer is the most frequently diagnosed male cancer and urinary incontinence represents a major consequence following surgery. Penile compression clamps (PCCs) which externally occlude the urethra may be used to manage the incontinence. Despite potential complication of PCCs, such as deformation-inflicted...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23172
更新日期:2017-08-01 00:00:00
abstract:OBJECTIVES:To create an animal model for neurogenic underactive bladder disease (UAB) and identify markers to describe secondary myogenic changes in the bladder wall. MATERIALS AND METHODS:Male rats underwent either bilateral pelvic nerve injury or sham surgery. Four weeks after surgery functional evaluation was perfo...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.23517
更新日期:2018-06-01 00:00:00
abstract:AIMS:To investigate whether vaginal estrogen cream combined with tolterodine is more effective than tolterodine alone in the treatment of postmenopausal women with overactive bladder (OAB). MATERIALS AND METHODS:This is an unblinded study without placebo. A preliminary study consisted of tolterodine 2 mg twice per day...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,随机对照试验
doi:10.1002/nau.20583
更新日期:2009-01-01 00:00:00
abstract:AIMS:To determine whether activity of the pelvic floor (PF) and abdominal muscles differs between continent and incontinent women in response to a postural perturbation with a moderately full or empty bladder. METHODS:Electromyographic (EMG) activity of the PF and abdominal muscles was recorded with surface electrodes...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章
doi:10.1002/nau.20336
更新日期:2007-01-01 00:00:00
abstract:AIM:NK-1 receptors in sensory nerves, the spinal cord and bladder smooth muscle participate in complex sensory mechanisms that regulate bladder activity. This study was designed to assess the efficacy and safety of a new NK-1 receptor antagonist, netupitant, in patients with OAB. METHODS:This was a phase II, multicent...
journal_title:Neurourology and urodynamics
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1002/nau.22406
更新日期:2014-03-01 00:00:00