New concepts in relation to urge and detrusor activity.

Abstract:

:Investigations of micromotion characteristics of bladder wall strips and pressure wave phenomena in total bladders in vitro and in vivo indicate that micromotion phenomena occur in the bladder wall. Local contractions can occur without an increase in tension or pressure, because other parts are in antiphase. Local contractions stretch surrounding tissues, which can stimulate fast stretch receptors. Synchronisation of these micromotion phenomena appears to be possible. Hence, above threshold levels urge can theoretically occur, even in the absence of a pressure increase. This hypothesis could explain the weak relation between urge and pressure. The distinction between motor and sensory urge could be artifactual based on a misunderstanding of fundamental bladder wall processes.

journal_name

Neurourol Urodyn

authors

Coolsaet BL,Van Duyl WA,Van Os-Bossagh P,De Bakker HV

doi

10.1002/nau.1930120504

subject

Has Abstract

pub_date

1993-01-01 00:00:00

pages

463-71

issue

5

eissn

0733-2467

issn

1520-6777

journal_volume

12

pub_type

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