Abstract：
:Previous studies have shown the adversely neurodevelopmental effects of exposure to benzo(a)pyrene (BaP) at early life stage. However, it is unclear the effects of lactational exposure to environmentally relevant BaP on anxiety-like behavior and the molecular mechanisms related. In this study, lactational exposure to 1 and 10 μg/kg bw BaP from postnatal day 3-21 caused anxiety-like behavior and alterations of the expressions of the neurodevelopment and anxiety-related genes in adolescence male mice using O cycle maze. Moreover, BaP exposure increased the expression level of glial fibrillary acidic protein, a typical marker of astrocytes, in hippocampus of male offspring. The release of pro-inflammatory cytokines interleukin 6 and tumor necrosis factor α was also elevated in BaP-treated offspring. Further, lactational exposure to BaP decreased the level of glutathione and the expressions of antioxidant genes (Thioredoxin 1 and Glutaredoxin 2) in male offspring. Our study demonstrated that environmentally relevant BaP lactational exposure caused anxiety-like behavior in male offspring involved in astrocytic activation, neuroinflammation, and antioxidant capability dysfunction.
journal_name
Chemospherejournal_title
Chemosphereauthors
Yang C,Han P,Ruan F,Zhou T,Luo B,Qiu Y,Lin Y,Lin Z,He Cdoi
10.1016/j.chemosphere.2019.01.006subject
Has Abstractpub_date
2019-04-01 00:00:00pages
67-74eissn
0045-6535issn
1879-1298pii
S0045-6535(19)30006-2journal_volume
221pub_type
杂志文章相关文献
CHEMOSPHERE文献大全abstract：:Physiological responses allow populations to cope with metal contamination and can be involved in the evolution of tolerance under historical metal contamination scenarios. Here we investigate physiological aspects that might be underlying the heritable high tolerance to cadmium (Cd) in two Chironomus riparius populat...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.12.008
更新日期：2017-03-01 00:00:00
abstract：:Sulfonamides (SAs) are a group of antibiotic drugs widely used in veterinary medicine. The contamination of the environment by these pharmaceuticals has raised concern in recent years. However, knowledge of their (eco)toxicity is still very basic and is restricted to just a few of these substances. Even though their t...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.06.058
更新日期：2011-10-01 00:00:00
abstract：:Understanding the interaction between pulmonary surfactant (PS) and inhalable pollutants is vital for risk assessment of respiratory health. Here, PS extracted from porcine lung (EPS) was used to investigate the interaction of PS with nano-silica particles and polycyclic aromatic hydrocarbons (PAHs). Our results demon...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.02.002
更新日期：2019-05-01 00:00:00
abstract：:This study aims to provide a passive sampling approach which can be routinely used to investigate polychlorinated biphenyl (PCB) sources in rivers. The approach consists of deploying low density polyethylene (LDPE) strips downstream and upstream of potential PCB sources as well as in their water discharges. Concentrat...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2014.09.032
更新日期：2015-01-01 00:00:00
abstract：:Newspapers impregnated with NaCl mixed with various chloride metals (CuCl2, MgCl2, MnCl2, FeCl3, NiCl2, and CoCl2) and electric wire coated with polyvinyl chloride (PVC) were combusted in a well-controlled incinerator. Exhaust gas samples collected at the outlet of the incinerator were analyzed for dioxins (PCDDs, PCD...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2004.08.104
更新日期：2005-02-01 00:00:00
abstract：:Diffusive isotope fractionation of non- and perdeuterated benzenes and toluenes in aqueous solution was investigated. The experimental method was based on a Stokes diaphragm cell. The isotope composition of diffusate and retentate was found to be identical within a range of uncertainty of ±5‰ for benzene and ±10‰ for ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127357
更新日期：2020-11-01 00:00:00
abstract：:Antibiotics are emerging contaminants, which wing to their bioactivity, may lead to short-term and long-term alterations of natural microbial communities in aquatic environment. We investigated the effects of antibiotics on biofilm bacterial communities in the Llobregat River (Northeast Spain). Three sampling sites we...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2013.01.063
更新日期：2013-08-01 00:00:00
abstract：:Reduction and recycling of Cr(VI) can offer environmental governance and sustainable development. Polypyrrole/sugarcane bagasse composites (PPy/SCB) for efficient adsorption and reduction of Cr(VI) in wastewater were prepared by in-situ polymerization. The effects of the initial pH, Cr concentration, adsorbent dosage,...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2021.129606
更新日期：2021-01-11 00:00:00
abstract：:Three pot experiments were conducted to investigate the role of arbuscular mycorrhiza (AM) in Zn uptake by red clover. Plants inoculated with Glomus mosseae and uninoculated controls were grown in a sterile calcareous soil in 'Plexiglas' (Acrylic) containers with two nylon net partitions (30 microm mesh) to separate t...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(02)00228-x
更新日期：2003-02-01 00:00:00
abstract：:In order to identify the contribution to health risk derived from various emission sources, this study investigated monsoon variations in PM2.5 mass and concentrations of the associated trace elements in a region with complex pollution sources in central Taiwan. This study applied the Chemical Mass Balance model to an...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.128462
更新日期：2021-02-01 00:00:00
abstract：:A laboratory scale study on treatment performances and fouling of entrapped cells-based-anaerobic membrane bioreactor (E-AnMBR) in comparison with suspended cells-based-bioreactor (S-AnMBR) treating domestic wastewater was conducted. The difference between E-AnMBR and S-AnMBR was the uses of cells entrapped in phospho...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2017.08.113
更新日期：2017-11-01 00:00:00
abstract：:The disinfection of helminth eggs and Escherichia coli contaminated aqueous solutions, was studied using an electro-Fenton reactor equipped with a polarized activated carbon (AC) packed bed and two chambers loaded with cation exchange resins. Experiments using different arrangements and operation conditions, revealed ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.126260
更新日期：2020-07-01 00:00:00
abstract：:Organochlorine pesticides are persistent lipophilic organic pollutants and tend to accumulate in growing plants. During growth, cork is in contact with the open air for long periods (9-12 years). Owing to the previous widespread use of organochlorine pesticides and their high persistence in the environment, there is a...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.11.009
更新日期：2012-02-01 00:00:00
abstract：:While surface morphology is the key parameter affecting membrane performance, its exact roles on membrane fouling have not well unveiled. In this study, effects of membrane surface roughness on fouling caused by alginate adhesion were investigated by thermodynamic techniques of the extended Derjaguin-Landau-Verwey-Ove...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.05.262
更新日期：2019-10-01 00:00:00
abstract：:In this paper, the response mechanism of activated sludge exposed to low-dose ozone at less than 20mgO(3)g(-1) total suspended solids (TSS) was studied by analyzing the changes in sludge activity and the evolution of C, N, P and metals from sludge following ozonation. The intracellular ATP concentration was not affect...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2009.07.047
更新日期：2009-09-01 00:00:00
abstract：:During foraging, bees are exposed to sublethal doses of insecticides, which can cause morphological changes to various organs, such as the midgut, Malpighian tubules, and mushroon body. Thus, the purpose of this study was to establish a scoring system to evaluate these alterations based on the damage caused and its re...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.06.225
更新日期：2019-12-01 00:00:00
abstract：:Polycyclic aromatic hydrocarbons (PAHs), with diverse sources and acute toxicity, are categorized as priority pollutants. Previous studies have stated that the hydrophobic effect controls PAH sorption, but no study has been conducted to quantify the exact contribution of the hydrophobic effect. Considering the well-de...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.10.143
更新日期：2017-02-01 00:00:00
abstract：:Decabromodiphenyl ether (BDE209) and lead (Pb) are the two common contaminants at e-waste recycling sites (EWRSs). A laboratory incubation study was conducted to explore the impacts of a step and repeated BDE209-Pb exposures on accumulation and metabolism of BDE209 in earthworms Eisenia fetida for the first time. The ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.06.009
更新日期：2016-09-01 00:00:00
abstract：:The presence of polybrominated diphenyl ethers (PBDEs) from mono to hepta brominated and 11 hydroxylated (OH-) and methoxylated (MeO-) PBDEs was examined in 37 breast milk samples collected from 11 mothers living in Barcelona. An extraction method based on accelerated solvent extraction followed by gas chromatography ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2008.09.050
更新日期：2009-01-01 00:00:00
abstract：:This work was carried out to evaluate the arsenic (As) levels in milk samples of different milch animals, sheep, goats, cows, buffaloes and camels in Tharparkar, Pakistan. The concentration of As in the milk samples of cows, buffalos, sheep, goats and camels were observed in the range of 15.1-18.4, 2.6-7.7, 25.7-33.2,...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2016.09.015
更新日期：2016-12-01 00:00:00
abstract：:Fourteen organochlorine pesticides (OCPs) residues were analyzed in 10 brands of processed cereal-based complementary foods with the aim of assessing the health risk to infants and young children. The QuEChERS method was used for extraction and clean-up of pesticide residues. Subsequent detection and quantification we...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2015.02.056
更新日期：2015-08-01 00:00:00
abstract：:Solvent-extractable organic compounds in the rain and snow collected at local cities in the mountainous region in central Japan, were analyzed by GC/MS and GC. Pinonaldehyde (2,2-dimethyl-3-acetyl-cyclobutyl-ethanal), an atmospheric reaction product of alpha-pinene, was detected in the rain and snow for the first time...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(01)00024-8
更新日期：2001-11-01 00:00:00
abstract：:This study presents the first systematic information on the degradation patterns of clandestine drug laboratory chemicals in soil. The persistence of five compounds - parent drugs (methamphetamine, 3,4-methylenedioxymethamphetamine (MDMA)), precursor (pseudoephedrine), and synthetic by-products N-formylmethylamphetami...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.06.102
更新日期：2011-10-01 00:00:00
abstract：:Among nanomaterials, zinc oxide (ZnO) is notable for its excellent biocidal properties. In particular, it can be incorporated in mortars to prevent biofouling. However, the morphology of these nanomaterials (NMs) and their impact on the action against biofouling are still unknown. This study aimed to assess how the mo...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2019.02.093
更新日期：2019-06-01 00:00:00
abstract：:Given the millions of coal-fired power stations worldwide and the generalization of co-firing technologies in the near future, the aqueous extraction experiments were taken to study the effects of oxides on Cr mobility in ashes through SiO2-Al2O3-Fe2O3-CaO system. The results identify that both the component and the s...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2020.127112
更新日期：2020-10-01 00:00:00
abstract：:The decomposition of (14)C-fenitrothion on silica gel chromatoplates as well as in polar and non polar solvents under sunlight and ultraviolet light was investigated, Its stability to sunlight on leaf surfaces of bean plants and on different surfaces (such as glass, quartz and plastic) was also determined. The main ph...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2007.07.063
更新日期：2008-02-01 00:00:00
abstract：:This study systematically investigates the characteristic degradation behaviors of dimethylsulfoxide (DMSO) by the streamer corona discharge process (SCDP) in water. The analysis of the oxidized intermediates of DMSO shows that hydroxyl radical (*OH) is the main oxidant responsible for the degradation of DMSO in the S...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2006.03.064
更新日期：2006-11-01 00:00:00
abstract：:Microcosm studies were undertaken to relate biomarker responses to the toxicities in soil ecosystems contaminated by phenanthrene (Phe) and pyrene (Pyr), both singly and combined. Growth inhibition, enzyme activity, MDA content, sperm count, neutral-red retention time (NRRT) and annetocin and TCTP gene transcriptions ...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2011.11.055
更新日期：2012-04-01 00:00:00
abstract：:A simple Ca(OH)(2)-based replacement-precipitation process was applied to the removal of EDTA-chelated copper from wastewaters. The effect of initial pH of the solution, molar ratio of Ca(2+) to Cu(II), the presence of CO(2) on the removal efficiency was investigated. The experimental results showed that the Ca(OH)(2)...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/j.chemosphere.2008.06.010
更新日期：2008-10-01 00:00:00
abstract：:Thirteen paddy soil profiles and river sediments which are sources of irrigation water were collected around the Taihu Lake, and the trace elements were estimated. The content of La and Ce in paddy soil and sediment were 39.3 and 68.6 mg/kg soil and 36.9 and 65.1 mg/kg soil, being within the range of background values...
journal_title：Chemosphere
pub_type： 杂志文章
doi：10.1016/s0045-6535(02)00209-6
更新日期：2003-02-01 00:00:00
