Normal Atlanto-Occipital Interval in Adults of Southeast Nigeria: An Evaluation of the Effect of Age, Sex, and Race.

Abstract:

BACKGROUND:Imaging of the craniocervical junction (CCJ) after trauma is crucial for injury detection and description. Of all the anatomic measurements of the CCJ, the normal value of atlanto-occipital interval (AOI) is not yet well established in adults. The aim of our study is to determine the normal values of the AOI in Nigerians aged between 21 and 60 years using multidetector computed tomography (MDCT) scan and to determine racial, age, and sex differences. METHODS:This was a prospective observational study done at Memfys Hospital for Neurosurgery, Enugu, Nigeria, between May 2016 and April 2017. There were 240 subjects (120 men and 120 women) divided into the following age groups: 21-30, 31-40, 41-50, and 51-60 years. Non-Nigerians and those with preexisting CCJ abnormalities were excluded. Normal values were those within the 95% confidence interval. Results were analyzed for possible sex and age variations and compared with the available literature for racial differences. Ethical approval was obtained for this study. RESULTS:The measured normal computed tomography value of the AOI in adult Nigerians was 1.181 ± 0.018 mm. The values in the age groups of 21-30, 31-40, 41-50, and 51-60 years were 1.279 ± 0.038, 1.164 ± 0.033, 1.151 ± 0.029, and 1.133 ± 0.033 mm, respectively (P < 0.05). The average normal values in men and women were 1.188 ± 0.025 and 1.174 ± 0.026 mm, respectively. The interobserver reliability test using the Cronbach α was 0.938. CONCLUSIONS:AOI values in this study were higher than previous MDCT-based values in non-African populations. The AOI decreased linearly with age and did not show any sex difference.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Ekuma EM,Ndubuisi CA,Mezue W,Ohaegbulam S

doi

10.1016/j.wneu.2019.03.023

subject

Has Abstract

pub_date

2019-06-01 00:00:00

pages

e1012-e1016

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(19)30649-7

journal_volume

126

pub_type

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