MRI Prognostication Factors in the Setting of Cervical Spinal Cord Injury Secondary to Trauma.

Abstract:

OBJECTIVE:Several studies have looked for an association between radiologic findings and neurologic outcome after cervical trauma. In the current literature, there is a paucity of evidence proving the prognostic role of soft tissue damage or bony integrity. Our objective is to determine radiologic findings related to neurologic prognosis in patients after incomplete acute traumatic cervical spinal cord injury, regardless of initial neurologic examination results. METHODS:We retrospectively reviewed patients with acute traumatic cervical spinal cord injury who had a magnetic resonance imaging (MRI) performed within the first 96 hours. Clinical and epidemiologic data were recorded from the medical records along with several radiologic findings from the initial computed tomographic scan and MRI. Data were analyzed using a non-parametric test. Significant prognostic factors were analyzed through a stepwise multivariable logistic regression, adjusted by neurologic status at baseline. The receiver-operating characteristic curve was used to test the discriminative capacity of the model. RESULTS:Eighty-six patients (68 males and 18 females) were included for the analysis. Mean age was 49 years. Ligamentum flavum injury, intramedullary edema larger than 36 mm, and facet dislocation were demonstrated to be associated with a lack of neurologic improvement at follow-up. Multivariable analysis showed that edema larger than 36 mm and facet dislocation were strong predictors of clinical outcome, regardless of the initial neurologic examination result. CONCLUSION:Early MRI has an intrinsic prognostic value. Ligamentous injury and larger edema are strong predicting factors of a bad neurologic outcome at long-term follow-up.

journal_name

World Neurosurg

journal_title

World neurosurgery

authors

Martínez-Pérez R,Cepeda S,Paredes I,Alen JF,Lagares A

doi

10.1016/j.wneu.2017.02.034

subject

Has Abstract

pub_date

2017-05-01 00:00:00

pages

623-632

eissn

1878-8750

issn

1878-8769

pii

S1878-8750(17)30196-1

journal_volume

101

pub_type

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