Abstract:
OBJECTIVE:Vasospasm developing after subarachnoid hemorrhage (SAH) is an important cause of mortality and morbidity. Lutein is a carotenoid with antioxidant and anti-inflammatory properties. The aim of present study was to investigate effects of lutein on the basilar artery and nerve tissues. METHODS:Wistar rats were randomly divided into 3 groups: control (group 1), SAH (group 2), and SAH treated with lutein (group 3). Lutein was administered for 3 days by means of orogastric gavage. Basilar artery lumen area, wall thickness, serum total antioxidant status, serum total oxidant status, and oxidative stress index were calculated. Histopathologic and immunohistochemical analyses were conducted. RESULTS:No statistically significant difference was found between groups in terms of wall thickness; lumen area; and serum total antioxidant status, serum total oxidant status, and oxidative stress index values. A statistically significant difference was found between groups colored with terminal deoxynucleotidyl transferase dUTP nick end labeling (P < 0.005). Post hoc analysis was used to examine the results between groups. Results of group 1 and group 3 were equal (P = 1) and lower than group 2 (P = 0.04 and P = 0.006, respectively). CONCLUSIONS:Lutein was found to have a positive effect on width of the basilar artery lumen area. Therefore, positive effects of lutein on vasospasm might be statistically significant if lutein is administered at higher doses. Lutein was found to be effective in preventing brain damage after SAH. To our knowledge, this study is the first in the literature to examine the effect of lutein on vasospasm and brain damage after SAH.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Turk C,Camlar M,Diniz G,Arslan FD,Oren MM,Ozer Fdoi
10.1016/j.wneu.2020.07.186subject
Has Abstractpub_date
2020-11-01 00:00:00pages
e450-e455eissn
1878-8750issn
1878-8769pii
S1878-8750(20)31708-3journal_volume
143pub_type
杂志文章abstract::This report portrays an unusual presentation of a dysembryoplastic neuroepithelial tumor characterized by a chronic, enlarging, heterogeneously enhancing organizing hematoma. Differential diagnoses included the malignant transformation of a low-grade glioma, radiation necrosis, and radiation-induced cavernoma. A dysem...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.08.036
更新日期:2019-11-01 00:00:00
abstract:BACKGROUND:Complex intracranial aneurysms are often treated with endovascular stent-assisted coiling. Intracranial stents are difficult to visualize with conventional computed tomography (CT) or fluoroscopy. "Stent view" flat-detector CT can be used to visualize intracranial stents during endovascular treatment. METHO...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2010.07.042
更新日期:2011-02-01 00:00:00
abstract:OBJECTIVE:The goal of this study was to assess the indications of revision for vagal nerve stimulation at a single institution in an adult population with drug-resistant epilepsy. METHODS:This was a retrospective review of a prospectively collected database who underwent vagal nerve stimulator implantation for drug-re...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.09.008
更新日期:2018-12-01 00:00:00
abstract:BACKGROUND:Pyogenic spondylodiskitis is an infection of intervertebral disks and spinal vertebral bodies. Various minimally invasive approaches to the infected disk spaces/abscesses have been described for management of early stages of the infection. Patients with chronic occurrence present with extensive infection, ne...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.05.076
更新日期:2016-08-01 00:00:00
abstract:OBJECTIVE:We sought to assess the validity of a virtual surgical training system on lumbar pedicle screw placement for residents. METHODS:Ten inexperienced residents were randomly assigned to the simulation training (ST) group (n = 5) and control group (n = 5). The ST group performed the lumbar pedicle screw placement...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.12.015
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Flow diversion for treatment of intracranial aneurysms frequently necessitates covering adjacent branch vessels. Although branch vessel occlusion is common, associated clinical deficits are rare. It has been hypothesized that clinically silent branch vessel occlusion is due to underlying collateral circulati...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.12.064
更新日期:2018-12-26 00:00:00
abstract:BACKGROUND:Atraumatic acute subdural hematoma (ASDH) associated with moyamoya disease (MMD) is rare, and only a few studies have reported the bleeding origin. We present a case of atraumatic ASDH attributable to a transdural anastomosis that developed owing to the compensatory mechanisms involved in the pathogenesis of...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.06.197
更新日期:2018-10-01 00:00:00
abstract:BACKGROUND:Cluster Headache (CH) is most painful primary headache sometimes lead to poor quality of life and associated disability. So far not have treatment way to cured the CH. in this study, we introduce the novel and effective surgery for CH. METHOD:Six patients with CH, the diagnosis of CH matched on criteria of ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.12.059
更新日期:2020-12-17 00:00:00
abstract:BACKGROUND:Indications for reconstruction of the common carotid artery (CCA) include trauma, iatrogenic injury, neoplastic growth (such as invasive neck carcinomas), postoperative infection, and cervical carotid aneurysm. Although various techniques and conduits have been described, the clinical scenario may preclude t...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2019.05.215
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Peroneal intraneural ganglion cysts (IGCs) are nonneoplastic lesions. They are responsible for a small number of footdrop cases, which occur after additional nerve damage. The earliest patient symptom related to IGCs is knee pain. CASE DESCRIPTION:A 17-year-old boy developed pain in the left knee, which pro...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.12.168
更新日期:2018-03-01 00:00:00
abstract:BACKGROUND:Microscopic training is essential for development of neurosurgical skills. A range of models is reported in the literature for this purpose, including live animals, exvivo, and synthetic material. Among the factors involved in selection and development of a training station, cost is a decisive one. METHODS:...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.06.089
更新日期:2019-10-01 00:00:00
abstract:BACKGROUND:Affective symptoms are frequent in patients with brain tumors. The origin of such symptoms is unknown; either focal brain injury or reactive emotional distress may be responsible. This cross-sectional pilot study linked depressive symptoms and anxiety to white matter integrity. The objective was to test the ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2015.05.031
更新日期:2015-10-01 00:00:00
abstract:BACKGROUND:With the continuous advancement of the spinal endoscopic technique in recent years, full-endoscopic operations provide a new approach for the treatment of migrated cervical disk herniation. CASE DESCRIPTION:A 42-year-old man presented with nuchal pain and limb numbness for 2 months, with recently developed ...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2019.08.054
更新日期:2019-12-01 00:00:00
abstract:OBJECTIVE:To analyze the clinical characteristics, immunohistochemistry, and treatment outcomes for skull base chordomas and the correlation between extent of resection/pathology type and outcomes. METHODS:The clinical materials of 77 consecutive patients with skull base chordomas were analyzed retrospectively. Follow...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2013.01.010
更新日期:2014-05-01 00:00:00
abstract:BACKGROUND:Artery stenting is an effective therapy for carotid artery stenosis to prevent ischemic stroke. We aimed to identify and analyze the 100 top-cited reports on carotid artery stenting (CAS) to review the achievements and developments in this field. METHODS:The Web of Knowledge database was searched from its i...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2018.11.042
更新日期:2019-02-01 00:00:00
abstract:BACKGROUND:Stent retrievers (SRs) can be used to perform mechanical thrombectomy for the treatment of acute major arterial occlusion. Recanalization is faster, and outcomes are better with treatment involving these devices than with internal treatment. Although several SRs are available, their clot-capturing abilities ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.09.106
更新日期:2019-01-01 00:00:00
abstract:INTRODUCTION:While surgical resection remains a primary treatment for accessible arteriovenous malformations (AVMs), stereotactic radiosurgery (SRS) has become thoroughly integrated into the AVM armamentarium; however, delayed sequelae of this treatment have become evident with increased long-term follow-up. To our kno...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2017.12.109
更新日期:2018-03-01 00:00:00
abstract:OBJECTIVES:Despite the increasing awareness of scientific fraud, no attempt has been made to assess its prevalence in neurosurgery. The aim of our review was to assess the chronologic trend, reasons, research type/design, and country of origin of retracted neurosurgical publications. METHODS:Three independent reviewer...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2017.04.014
更新日期:2017-07-01 00:00:00
abstract:BACKGROUND:Frailty is an increasingly studied tool for preoperative risk stratification, but its prognostic value for anterior cervical discectomy and fusion (ACDF) patients is unclear. We sought to evaluate the association of the 5-item modified Frailty Index (5i-mFI) with 30-day adverse outcomes following ACDF and it...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.10.154
更新日期:2020-11-03 00:00:00
abstract:OBJECTIVE:To review retrospectively experience with stent-assisted coiling of ophthalmic segment internal carotid artery (ICA) aneurysms to report outcome data and identify the rate of associated visual complications. METHODS:The Duke endovascular database was retrospectively reviewed to identify all ICA aneurysms tre...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2011.12.003
更新日期:2012-09-01 00:00:00
abstract:BACKGROUND:Pseudoarthrosis after spinal fusion is an important cause of pain, neurologic decline, and reoperation. METHODS:The Healthcare Cost and Utilization Project State Inpatient Databases were queried in New York, California, Florida, and Washington for adult patients who had undergone new spinal fusion from 2009...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.08.026
更新日期:2018-12-01 00:00:00
abstract:OBJECTIVE:The aims of this retrospective cohort study were to 1) identify new alignment risk factors for proximal junctional kyphosis (PJK) in adult spinal deformity (ASD) patients with lower thoracic upper instrumented vertebra (UIV) and 2) determine the effect of junctional tethers on PJK and UIV alignment. METHODS:...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.08.242
更新日期:2019-01-01 00:00:00
abstract:OBJECTIVE:This report describes 2 techniques for controlling otherwise difficult-to-control hemorrhage from choanoid bony foramina. METHODS:Medical records of 3 patients in whom vigorous and difficult-to-control bleeding from choanoid cranial foramina was successfully halted are reviewed. RESULTS:In 2 patients, vigor...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.01.128
更新日期:2017-04-01 00:00:00
abstract:BACKGROUND:Intraneural (IN) perineuriomas are a rare benign hypertrophic nerve tumor, most frequently occurring in young patients. Patients with IN perineurioma have been anecdotally found to have limb undergrowth; however, this has not been systematically evaluated. METHODS:Archived electronic records from 1990 to 20...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.05.280
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:The purpose of this study was to assess the radiologic and clinical outcomes after lumbar fusion intervention and to compare the established posterior lumbar interbody fusion (PLIF) technique and dynamic hybrid instrumentation (topping off). METHODS:In this prospective randomized trial, all patients who pres...
journal_title:World neurosurgery
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.wneu.2018.06.005
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Carcinoid tumors are neuroendocrine neoplasms derived from enterochromaffin cells. Central nervous system involvement is rare. The reported cases include metastases to brain or spinal cord, and primary skeletal or extradural disease resulting in compressive myeloradiculopathy. There are 2 previously reported...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.06.179
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Stereotactic radiosurgery (SRS) as a treatment for cerebral cavernous malformation (CCM) has been controversial, but there are few pathological reports showing its long-term therapeutic effect, and literature reporting the CCM cyst formation after SRS is also rare. CASE DESCRIPTION:We present a 30-year-old ...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2020.07.042
更新日期:2020-11-01 00:00:00
abstract:BACKGROUND:Experiencing cranial surgery under awake conditions may expose patients to considerable psychological strain. METHODS:This study aimed to investigate the occurrence and course of psychological sequelae following awake craniotomy (AC) for brain tumors in a series of 20 patients using a broad, validated psych...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.05.156
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Depression following resection of diffuse low-grade glioma has rarely been described. Location of the tumor and surgical route are potential causes. Lesion network mapping (LNM), leveraging high-quality resting-state functional magnetic resonance imaging data from large samples of healthy adults, has been us...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.10.020
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Primary central nervous system lymphoma (PCNSL) is an aggressive lymphoma confined to the CNS. Although the pathogenesis of PCNSL in immunocompetent individuals remains unclear, there have been several case studies demonstrating the "sentinel" inflammatory lesions months before the manifestation of PCNSL. Ho...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2015.11.099
更新日期:2016-04-01 00:00:00