Abstract：
BACKGROUND:Osteoporosis is one of the most common problems of patients with spinal cord injuries (SCIs). The current study aimed to evaluate the antiosteoporotic effects of curcumin on densitometry parameters and biomarkers of bone turnovers among patients with SCI. MATERIALS AND METHODS:The current controlled clinical trial was conducted among 100 patients with SCI referred to an outpatient clinic of rehabilitation in Ilam City, Iran, in 2013-2015. The intervention group received 110/mg/kg/day curcumin for 6 months and the control group received placebo. Bone mineral density (BMD) was measured in all patients. The level of procollagen type I N-terminal propeptide, serum carboxy-terminal telopeptide of type I collagen, osteocalcin, and bone-specific alkaline phosphates were compared before and after study. RESULTS:BMD indicators of lumbar, femoral neck, and total hip in the control group significantly decreased compared with the beginning of study. However, in the curcumin group, a significant increase was observed in BMD indicators of lumbar, femoral neck, and hip at the end of study compared with the beginning. There was also a significant difference between interventional and control groups for the mean BMD of femoral neck and hip at the end of study (0.718 ± 0.002 g/cm2 vs. 0.712 ± 0.003 g/cm2 and 0.742 ± 0.031 g/cm2 vs. 0.692 ± 0.016 g/cm2, respectively). CONCLUSIONS:Curcumin, via modulation of densitometry indices and bone resorption markers, showed inhibitory effects on the process of osteoporosis. Treatment with curcumin was significantly associated with a decrease in the osteoporosis progression and bone turnover markers of patients with SCI after 6 months.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Hatefi M,Ahmadi MRH,Rahmani A,Dastjerdi MM,Asadollahi Kdoi
10.1016/j.wneu.2018.03.081subject
Has Abstractpub_date
2018-06-01 00:00:00pages
e785-e791eissn
1878-8750issn
1878-8769pii
S1878-8750(18)30559-Xjournal_volume
114pub_type
杂志文章abstract：BACKGROUND:Spinal extradural arachnoid cysts are relatively uncommon. Rarely, large cysts presented with spinal cord compression requiring surgical intervention. CASE DESCRIPTION:We report a patient with a progressively enlarging spinal extradural arachnoid cyst causing worsening right S1 radiculopathy and gastrocnemi...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.10.003
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Subdural drain (SDD) and Subdural Evacuating Port System (SEPS) are bedside options for management of nonacute subdural hematomas (SDHs). These interventions have not been compared with each other. Our objective is to compare the need for second bedside procedure, need for craniotomy, complication rate, and ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.03.226
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Indocyanine green videoangiography (ICG-VA) after clipping can be misleading in evaluating aneurysm exclusion when the dye is injected before clipping. This is due to indocyanine green (ICG) entrapment by the clip blades in the aneurysm dome. METHODS:We examined the intraoperative findings of 7 patients pre...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.10.011
更新日期：2017-01-01 00:00:00
abstract：BACKGROUND:Intracranial arterial dissection is an uncommon but well-recognized entity. Treatment remains variable, ranging from observation to intervention via the use of either surgical or endovascular techniques. Aneurysms along the lenticulostriate artery have been reported in only 41 patients. With the current case...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2012.12.006
更新日期：2014-02-01 00:00:00
abstract：OBJECTIVE:Preoperative embolization may facilitate skull base meningioma resection, but its safety and efficacy in the Onyx era have not been investigated. In this retrospective cohort study, we evaluated the outcomes of preoperative embolization of skull base meningiomas using Onyx as the primary embolysate. METHODS:...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.04.208
更新日期：2018-08-01 00:00:00
abstract：:Acute lymphoblastic lymphoma is a malignant hematologic disease in childhood but rarely initially involves epidural compartment in adults. A 20-year-old male presented with progressive osphyalgia with constipation. Contrasted magnetic resonance imaging showed multiple vertebrae of hypointense T1 signals and an intrasp...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.09.130
更新日期：2018-01-01 00:00:00
abstract：BACKGROUND:Chronic subdural hematoma (cSDH) is a common neurosurgical condition, with an estimated incidence of 3-15.5 per 100,000 people, with significantly higher rates in the elderly population. Recurrence rates range from 2%-37% after surgical drainage. Studies have shown that leaving a drain postoperatively can re...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.08.069
更新日期：2016-11-01 00:00:00
abstract：BACKGROUND:The ideal treatment method for cranial arachnoid cysts stills controversial, each of endoscopic and microscopic techniques has its pros and cons. METHODS:We described cystocisternostomy technique for arachnoid cysts through fenestration medial to the edge of tentorium through lateral pontomesencephalic memb...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.12.108
更新日期：2020-12-29 00:00:00
abstract：OBJECTIVE:To investigate the noninferiority of facet joint- and nuchal ligament-sparing laminectomy (FNL) compared with conventional open-door laminoplasty. METHODS:This retrospective study analyzed 31 patients who underwent FNL (7 women; median age, 71 years) and 29 patients who underwent laminoplasty (9 women; media...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.01.187
更新日期：2020-05-01 00:00:00
abstract：BACKGROUND:Freehand ventriculostomy is one of the most commonly performed neurosurgical procedures. While a variety of approaches have been described, frontal via Kocher's point is the most common. Multiple trajectories have been described, but no consensus exists as to the most efficacious. Our objective was to assess...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.11.065
更新日期：2020-11-30 00:00:00
abstract：BACKGROUND:Although carotid artery stenting (CAS) has been widely acknowledged as an effective alternative option for patients at high risk of carotid endarterectomy, embolic stroke is a major complication of CAS. Several reports have emphasized that distal protection filter alone is associated with a high risk of embo...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.05.028
更新日期：2020-09-01 00:00:00
abstract：BACKGROUND:Cranial defects following anterior cranial base surgery have been frequently reconstructed using the pericranial flap. METHODS:We present a simple technique for preparing the flap using injection of saline into the subgaleal space. RESULTS:We inserted a 20-gauge needle perpendicular to 8-10 spots in the fr...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.12.019
更新日期：2017-03-01 00:00:00
abstract：BACKGROUND:Double crush of a nerve at the root level is not common. We describe here a double crush of the right L4 nerve with foramina to far lateral disk (ventral) and extraforaminal (dorsal) compression. The double crush was managed by endoscopy with a contralateral uniportal approach from the left interlaminar spac...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.11.110
更新日期：2019-02-01 00:00:00
abstract：OBJECTIVE:Two main types of embolic protection devices have been used during carotid artery stenting (CAS): distal protection devices (DPDs) and proximal protection devices (PPDs). We compared the complications, clinical outcomes, and new ischemic lesions on diffusion-weighted magnetic resonance imaging (DWI) studies b...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.12.121
更新日期：2020-03-01 00:00:00
abstract：BACKGROUND:Ankylosing spondylitis (AS) is an inflammatory disease that involves above all the spine and the pelvis. In the spine, the inflammatory processes cause the formation of syndesmophytes between the vertebral bodies and the ossification of ligaments, with bony overgrowth. In this setting, dysphagia is a rare bu...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.04.031
更新日期：2020-07-01 00:00:00
abstract：:An elderly woman was transferred for biopsy of a pontine lesion. Her condition, including gait disturbances, truncal ataxia, and dysarthria-presumed to be due to severe alcohol abuse-had deteriorated during treatment of ambulatory-acquired pneumonia. No electrolyte abnormalities were noted during hospitalization. Howe...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.05.061
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:The role of adjuvant radiation after gross total resection (GTR) for grade II meningioma is evolving, prompting further evaluation in NRG-BN003, a phase 3 national trial. Furthermore, the relationship between facility volume and outcomes in patients with grade II meningioma after GTR has not been examined at...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.05.030
更新日期：2020-09-01 00:00:00
abstract：:This report portrays our pitfall in the initial diagnosis of an intracranial arterial dissection that we misinterpreted as a saccular aneurysm. Intracranial arterial dissections presenting with convexity subarachnoid hemorrhage are rare, thus being easily mistaken with mild traumatic head injuries and therefore preven...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.11.145
更新日期：2017-02-01 00:00:00
abstract：OBJECTIVE:Currently, radiologic predictors for the resectability of cervical dumbbell schwannomas remain unknown. To identify radiologic predictors for resectability, we retrospectively reviewed data from 72 patients. METHODS:From January 1995 to June 2017, 72 patients who underwent surgical treatment for cervical dum...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.09.186
更新日期：2019-01-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2021.01.015
更新日期：2021-01-11 00:00:00
abstract：OBJECTIVE:There is a lack of consensus regarding diagnosis, timing, and method of intervention for progressive enhancement on surveillance imaging after stereotactic radiosurgery (SRS) treatment of brain metastases. We sought to characterize current practices among neurosurgeons in identifying and treating infield tumo...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.04.046
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Since the 1980s, numerous operations have replaced posterior lumbar interbody fusion (PLIF) with human bone. These operations often involve expensive implants and complex procedures. Escalating expenditures in lumbar fusion surgery warrant re-evaluation of classical PLIF with allogeneic ilium and without ins...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.03.210
更新日期：2018-07-01 00:00:00
abstract：OBJECTIVE:Although short-term clinical outcomes after basilar artery stent placement have been reported previously, effectiveness of intracranial stenting for vertebrobasilar artery occlusion in the acute phase of ischemic stroke is unclear. METHODS:We clinically investigated 8 patients with intracranial percutaneous ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.09.106
更新日期：2017-01-01 00:00:00
abstract：:The transition from the medieval universities to the secular, second generation universities in Turkey occurred in the period from 1773 to 1945. The Ottoman Empire's efforts to establish a higher education system in the eighteenth and nineteenth centuries only aimed at modernization of the armed forces, and the civil ...
journal_title：World neurosurgery
pub_type： 历史文章,杂志文章
doi：10.1016/j.wneu.2012.11.049
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:Intradiploic epidermoid cyst (IEC) concurrent with chronic epidural hematoma (CEDH) has never been reported in the literature. We report a unique case of IEC concurrent with anatomically close associated CEDH. CASE DESCRIPTION:A 54-year-old man presented with a 1-week history of headache, confusion, and dro...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.030
更新日期：2018-09-01 00:00:00
abstract：OBJECTIVE:To explore the feasibility and effectiveness of C1 lateral mass fixation via the posterior arch using pedicle screws of 3.5-mm diameter in patients whose atlas in the vertebral artery groove (C1 pedicle) was ≤3.5 mm in height. METHODS:A total of 14 patients who underwent transposterior arch lateral mass scre...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.175
更新日期：2019-07-01 00:00:00
abstract：BACKGROUND:Osteoid osteomas (OOs) are benign bone forming tumors that, usually, occur in the extremities, with about 10% of them arising in the spine more commonly in the posterior elements. The aim of this study is to evaluate the long-term results of patients suffering from spinal OO treated with surgery and radiofre...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.10.050
更新日期：2021-01-01 00:00:00
abstract：:Spinal cord stimulation is a safe method for treating chronic pain syndromes. Spinal cord stimulators can be placed either surgically by creating a laminectomy defect for paddle leads or percutaneously by inserting electrodes. They are usually not associated with major complications. There have been several reports of...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2017.05.152
更新日期：2017-08-01 00:00:00
abstract：OBJECTIVE:Posterior circulation strokes account for over one quarter of all ischemic strokes. The frequency of vertebral artery origin stenosis (VAOS) in patients with vertebrobasilar insufficiency (VBI) has been estimated to be as high 26%-32%, and VAOS is the direct cause of posterior circulation strokes in 9% of pat...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.203
更新日期：2019-10-01 00:00:00
abstract：OBJECTIVE:Intracranial psammomatous meningiomas (PMs) are rarely reported due to their extremely low incidence. Knowledge about intracranial PMs is therefore poor. This study aimed to analyze the incidence, clinical features, radiologic findings, and surgical outcomes of intracranial PMs. METHODS:Approximately 5651 in...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.01.056
更新日期：2017-04-01 00:00:00
