Abstract:
BACKGROUND:Spontaneous regression in intracranial germ cell tumors (GCTs) is an extremely rare phenomenon with only 9 cases reported. The mechanism and natural history of this phenomenon are still equivocal. METHODS:A 12-year-old boy presented with a lesion in the suprasellar region with involvement of basal ganglia and corpus callosum. After 1 month, his symptoms were relieved, and magnetic resonance imaging demonstrated a remarkable regression of the lesion. Three months later, the boy's symptoms deteriorated, and magnetic resonance imaging revealed regrowth and enlargement of the lesion. Diagnosis of germinoma was confirmed via biopsy, and radiation therapy achieved complete response. We performed a systematic literature review of spontaneous regression of intracranial GCTs. The natural history of these cases was analyzed, and hypotheses in the studies were discussed. RESULTS:Spontaneous regression is extremely rare with only 10 cases reported, including the present case. There were 9 male patients and 1 female patient with mean age 22.1 ± 10.3 years (range, 12-43 years). Nine cases were diagnosed as germinoma, and 4 cases included an episode of regression followed by regrowth. The mechanism of tumor regression in intracranial GCTs remains unclear. Four hypotheses were proposed, including radiation exposure, surgical procedures, effects of steroids, and immune reaction triggered by intervention. CONCLUSIONS:Tumor regression in intracranial GCTs could be a iatrogenic transient phenomenon, caused by complex immune reactions triggered by interventions.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Zhang S,Li Q,Ju Ydoi
10.1016/j.wneu.2019.06.220subject
Has Abstractpub_date
2019-11-01 00:00:00pages
e32-e37eissn
1878-8750issn
1878-8769pii
S1878-8750(19)31877-7journal_volume
131pub_type
杂志文章,评审abstract:OBJECTIVE:We aimed to investigate the effect of coiling for small unruptured intracranial aneurysms (UIAs) (<5 mm) on progressive occlusion and recanalization, and the dubious factors related to progressive occlusion and recanalization among UIAs without complete occlusion. METHODS:A total of 264 patients with 287 sma...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.04.017
更新日期:2017-07-01 00:00:00
abstract:OBJECTIVE:To report on our experience with the Elekta Extend system, a relocatable frame system used in patients with brain metastases for single-session, hypofractionated, or staged hypofractionated Gamma Knife radiosurgery (GKRS); and the evaluation of its efficacy. METHODS:From March 2014 to September 2016, 856 pat...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.07.157
更新日期:2018-11-01 00:00:00
abstract:BACKGROUND:We performed a rigorous statistical analysis of the complications and outcomes of patients with ruptured or unruptured intracranial aneurysms. Our emphasis was on the potential predictive factors when both surgical and endovascular management are offered by a team with balanced microsurgical and endovascular...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.10.094
更新日期:2019-02-01 00:00:00
abstract:OBJECTIVE:Aneurysms of the posterior cerebral artery (PCA) are rare, and therefore the individual and institutional experience of their microsurgical management is usually limited. In the present article, we describe our experience with the subtemporal approach to aneurysms arising from the PCA. METHODS:We reviewed 34...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2015.01.042
更新日期:2015-05-01 00:00:00
abstract:OBJECTIVE:Incidence of intraprocedural rupture (IPR) during endovascular coiling is reported to be 2%-5%. We reviewed a single-center experience of IPR during coil embolization of unruptured intracranial aneurysms. METHODS:Between January 2011 and April 2016, 849 patients were treated with endovascular therapy for unr...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.05.147
更新日期:2017-09-01 00:00:00
abstract:BACKGROUND:Rosai-Dorfman disease (RDD) is a rare, benign histiocytosis disorder with only approximately 100 reported central nervous system cases in the literature. Even less common is skull base involvement of RDD, with about 41 reported cases. Radiographically, RDD can appear similar to a meningioma; the true diagnos...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2019.12.032
更新日期:2020-03-01 00:00:00
abstract:BACKGROUND:Intraneural (IN) perineuriomas are a rare benign hypertrophic nerve tumor, most frequently occurring in young patients. Patients with IN perineurioma have been anecdotally found to have limb undergrowth; however, this has not been systematically evaluated. METHODS:Archived electronic records from 1990 to 20...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.05.280
更新日期:2020-09-01 00:00:00
abstract:OBJECTIVE:Thrombectomy with aspiration catheters has shown to be effective for treatment of intracranial large vessel occlusion (LVO). We present preclinical evaluation of the safety and efficacy of React68 and React71 (Medtronic PLC, Irvine, CA) catheters in animal models of LVO. METHODS:In vivo evaluation of cathete...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.08.131
更新日期:2019-12-01 00:00:00
abstract::With the loss of function of an upper extremity because of stroke or spinal cord injury or a physical loss from amputation, an individual's life is forever changed, and activities that were once routine become a magnitude more difficult. Much research and effort have been put into developing advanced robotic prosthese...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2014.03.012
更新日期:2014-05-01 00:00:00
abstract:OBJECTIVE:The relationship between urgent decompression and neurologic recovery for traumatic spinal cord injury (TSCI) remains controversial. This meta-analysis was conducted to determine the beneficial effects of surgery within 8 hours for patients with TSCI. METHODS:A systematic search in EMBASE, MEDLINE, Cochrane ...
journal_title:World neurosurgery
pub_type: 杂志文章,meta分析
doi:10.1016/j.wneu.2020.04.230
更新日期:2020-08-01 00:00:00
abstract:BACKGROUND:A spontaneous persistent primitive trigeminal artery-cavernous sinus fistula (PCF) is extremely rare. Until recently, endovascular treatment for PCF involving transarterial and/or transvenous coil embolization of the cavernous sinus (with/without the persistent trigeminal artery) was commonly performed. Howe...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2019.05.003
更新日期:2019-08-01 00:00:00
abstract:OBJECTIVE:Some patients suffer postoperative hearing loss even when the intraoperative auditory brainstem response (ABR) is preserved during vestibular schwannomas surgery. This study was conducted to evaluate whether there are dynamic changes of the ABR after surgery. PATIENTS AND METHODS:In a prospective study from ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2016.07.085
更新日期:2016-11-01 00:00:00
abstract:BACKGROUND:Osteoid osteomas (OOs) are benign bone forming tumors that, usually, occur in the extremities, with about 10% of them arising in the spine more commonly in the posterior elements. The aim of this study is to evaluate the long-term results of patients suffering from spinal OO treated with surgery and radiofre...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.10.050
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Intracranial arterial dissection is an uncommon but well-recognized entity. Treatment remains variable, ranging from observation to intervention via the use of either surgical or endovascular techniques. Aneurysms along the lenticulostriate artery have been reported in only 41 patients. With the current case...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2012.12.006
更新日期:2014-02-01 00:00:00
abstract:BACKGROUND:Filum terminale arteriovenous fistula (FTAVF) with multiple shunt points has not been reported in the literature. In previous studies, the angioarchitecture of FTAVFs was always featured with only one single shunt point, and such a uniformity had established the preconceived and conventional understanding of...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.07.097
更新日期:2018-10-01 00:00:00
abstract:OBJECTIVE:A 63-year-old woman presented with diplopia resulting from abducens paralysis. Examination revealed a giant cavernous aneurysm supplied by the internal carotid artery (ICA) and primitive trigeminal artery (PTA) via the vertebrobasilar system. METHODS:After evaluation of balloon test occlusion (BTO) at the di...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2010.06.029
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:Medical implications of 3-dimensional (3D) printing technology have evolved and are increasingly used. Surgical spine oncology involves at times complex resection using various surgical approaches and unique spinal reconstruction. As high general complication rates, including hardware failure, are reported, ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2019.09.002
更新日期:2020-01-01 00:00:00
abstract:BACKGROUND:Cerebral cavernous malformations of the intracanalicular optic nerve are extremely rare lesions. Only a few case reports and 1 case series have been published. We report an additional case with atypical imaging and review the existing literature with attention to time to surgery and imaging characteristics. ...
journal_title:World neurosurgery
pub_type: 杂志文章,评审
doi:10.1016/j.wneu.2019.02.202
更新日期:2019-06-01 00:00:00
abstract:INTRODUCTION:Stereotactic radiosurgery (SRS), particularly Gamma Knife radiosurgery (GKRS) is an established treatment option for residual and recurrent pituitary adenoma tumors. It helps in the preservation of surrounding normal neuronal, vascular, and hormone-producing structures and causes fewer neurologic deficits....
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.03.094
更新日期:2018-06-01 00:00:00
abstract:BACKGROUND:Endoscopic surgery for lumbar stenosis is gaining acceptance because of the minimal muscle damage, short recovery times, reduced blood loss, and good clinical results. We report a novel technique of decompressing contralateral traversing and exiting nerve roots through a single interlaminar window, avoiding ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.05.111
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Although reoperation likely confers survival benefit for glioblastoma, whether the extent of resection (EOR) of the reoperation affects survival outcome has yet to be thoroughly evaluated in the current temozolomide (TMZ) era. The aim of this meta-analysis was to pool the current literature and evaluate the ...
journal_title:World neurosurgery
pub_type: 杂志文章,meta分析,评审
doi:10.1016/j.wneu.2019.03.250
更新日期:2019-07-01 00:00:00
abstract:OBJECTIVE:To investigate initial pain relief and subsequent recurrence after percutaneous balloon compression (PBC) and describe its association with the nature of trigeminal pain, previous procedures, or other clinical factors. METHODS:A total of 222 patients with medically refractory trigeminal pain treated with PBC...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2018.03.111
更新日期:2018-06-01 00:00:00
abstract:OBJECTIVE:To determine the impact of the 2019 novel coronavirus disease (COVID-19) pandemic on operative case volume in 8 U.S. neurosurgical residency training programs in early 2020 and to survey these programs regarding training activities during this period. METHODS:A retrospective review was conducted of monthly o...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.10.016
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:Metastases to the spine are a common manifestation of breast cancer leading to considerable reduction in the patient's quality of life. Physicians must consider the different treatments available to decrease pain, reduce tumor burden, and ensure spinal stability to prevent neurological compromises. The first ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2014.08.010
更新日期:2014-12-01 00:00:00
abstract:BACKGROUND:Fungal mass lesions in the central nervous system rarely reach a size large enough to directly cause neurologic deterioration. In terms of the etiologic incidence of fungal mass lesions in the central nervous system, whereas cryptococcomas may be the most common, they rarely reach any appreciable size. One f...
journal_title:World neurosurgery
pub_type:
doi:10.1016/j.wneu.2020.04.236
更新日期:2020-08-01 00:00:00
abstract:OBJECTIVE:Although hearing impairment after microvasuclar decompression (MVD) for hemifacial spasm (HFS) is not common, its occurrence could detrimentally affect the patient's surgical outcome. The object of this study is to address the optimal approaches for reducing postoperative hearing problems after MVD for HFS. ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.09.053
更新日期:2017-12-01 00:00:00
abstract:OBJECTIVE:Treatment of ruptured posterior circulation dissecting aneurysms is technically challenging with potentially high morbidity and mortality. We sought to assess the safety and feasibility of using a flow-diversion device (FDD) and a specific acute antiplatelet aggregation protocol in the management of ruptured ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.09.125
更新日期:2018-01-01 00:00:00
abstract:OBJECTIVE:To analyze the relationship between cognitive performance and white matter integrity in patients with temporal lobe epilepsy (TLE) to establish radiologic criteria to help with patient selection for surgery. METHODS:The study included 19 adults with temporal lobe epilepsy. A tractography analysis of fraction...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2020.03.103
更新日期:2020-07-01 00:00:00
abstract:OBJECTIVE:The aim of the study is to report the feasibility, safety, and outcomes associated with endovascular treatment (EVT) of unruptured intracranial aneurysms (UIAs) under local anesthesia. METHODS:Between March 2011 and December 2016, 184 consecutive patients with 198 UIAs were treated with coil embolization und...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.05.077
更新日期:2017-08-01 00:00:00
abstract:BACKGROUND:Cervical spondylitic myelopathy is a degenerative condition resulting from chronic spinal cord compression and a leading cause of nontraumatic spinal cord dysfunction. The chief surgical goal in the management of cervical spondylitic myelopathy is adequate spinal cord decompression with or without fusion to ...
journal_title:World neurosurgery
pub_type: 杂志文章
doi:10.1016/j.wneu.2017.11.017
更新日期:2018-02-01 00:00:00