[Aldose reductase inhibitor--a new way for preventing diabetic lens changes?].

Abstract:

:Increased blood sugar levels may influence the refractive power of the lens in juvenile diabetics, and can lead to the rare true diabetic cataract ("snow-storm cataract"). Surplus glucose induces accumulation of the sugar alcohol within the cells, thus generating disturbances of the osmotic balance and finally causing cataract. The enzyme aldose reductase catalyzes the formation of sorbitol. Experiments with animals have shown that aldose reductase inhibitors can prevent the formation of such opacities with streptozotocin-induced diabetes in rats. Numerous aldose reductase inhibitors are now known, but we still have insufficient knowledge to determine whether systemic or local administration is preferable. The mechanisms reported here are not relevant with respect to the frequent occurrence of senile cataract in older diabetics, which has often been described.

journal_name

Klin Monbl Augenheilkd

authors

Ohrloff C,Hockwin O,Korte I,Wegener A

doi

10.1055/s-2008-1050822

subject

Has Abstract

pub_date

1986-11-01 00:00:00

pages

361-2

issue

5

eissn

0023-2165

issn

1439-3999

journal_volume

189

pub_type

杂志文章
  • [Pressure-reducing effect of latanoprost 0.005%].

    abstract:BACKGROUND:Earlier studies in monkeys have shown that latanoprost 0.005% lowers the IOP by improving the uveoscleral Outflow. We wanted to know if this is also the case in the human eye. PATIENTS AND METHODS:We used our new aqueous humor outflow test with 2-nitrophenyl-acetate in 9 healthy human volunteers, mean age 3...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034877

    authors: Albach C,Wachsmuth ED,Velte K,Dekker P,Robert Y

    更新日期:1998-05-01 00:00:00

  • [The effects of the xenon arc lamp upon the iris of the pigmented rabbit eye (author's transl)].

    abstract::The ultrastructural alterations of 10 pigmented rabbit irides 15 minutes to 257 days after irradiation with a xenon arc lamp were analysed. Pulse duration was varied while irradiation power was kept constant at 3.24 W. 0.32 J (= 100 ms pulse duration) were delivered to the left eye and 3.2 J (= 1 second pulse duration...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Bernhard K,van der Zypen E,Fankhauser F

    更新日期:1979-06-01 00:00:00

  • [Eye involvement in cancer].

    abstract::Intraocular metastatic tumors are rare. They are seen in 10% of patients having died of a malignant tumor. Frequently metastatic tumors of the eye are not observed clinically because the may develop in the terminal stage of the disease. The most frequent primary tumor is carcinoma of the breast with 60% of all intraoc...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Vogel M

    更新日期:1997-04-01 00:00:00

  • [Nystagmus and torticollis in albinism (author's transl)].

    abstract::Two pairs of albinotic brothers, a severely myopic albino and an aged albinotic woman patient were examined; visual acuity was 0.2. In the nystagmogram there were varied rhythmic wave-forms with 1) oscillations of high frequency; 2) slow arrhythmic movements; 3) deviation tendencies with a fast nystagmus component. In...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057553

    authors: Piper HF

    更新日期:1980-05-01 00:00:00

  • [Retinal detachment following implantation of a posterior chamber lens].

    abstract::In a series of 6000 cases of pseudophakia following extracapsular cataract extraction and implantation of Simcoe-type posterior chamber lenses, observed for a minimum of 20 months, the incidence of retinal detachment was 21 cases (0.33%). Significant risk factors include male sex (18/21, 82%), high myopia (axial lengt...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050061

    authors: Wollensak J,Zeisberg B,Pham Duy T

    更新日期:1988-01-01 00:00:00

  • [Minimizing induction of astigmatism in preoperative spherical cornea a. by mini-incision surgery with foldable IOL and b. by corneal tunnel incision with limbal relaxing incision].

    abstract:BACKGROUND:In case of a spheric cornea preoperatively the refractive effect of a clear corneal cataract incision is undesirable. We studied two actual techniques to minimize the surgically induced astigmatism. PATIENTS AND METHODS:Temporal clear corneal incision was performed in 77 patients with practically spherical ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 临床试验,杂志文章

    doi:10.1055/s-2008-1034692

    authors: Müller-Jensen K,Fischer P

    更新日期:1999-09-01 00:00:00

  • ["The Retina of the Vertebrates" by Santiago Ramón y Cajal--100 years in German translation].

    abstract::1894 Richard Greeff, a young scientist at the University of Berlin, translated the book "The retina of vertebrates" of Santiago Ramón y Cajal into German. Greeff himself had already applied the Golgi-Cajal-Chromic-Silver dye to the retina and was enthusiastic about the results of Cajal. He interrupted his own investig...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 传,历史文章,杂志文章

    doi:10.1055/s-2008-1045547

    authors: Bergua A

    更新日期:1994-12-01 00:00:00

  • [Bilateral congenital microblepharon with ectropion and microphthalmus (author's transl)].

    abstract::A very rare combination of congenital malformations of the eyelids and eyes in a 6-month-old boy is reported. The main symptoms are a bilateral microblepharon associated with ectropion and bilateral aphakic microphthalmus. The pathogenesis of these changes is discussed. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057334

    authors: Klauss V,Mnyalla ND,Dechant W,Riedel K

    更新日期:1981-11-01 00:00:00

  • [Experiences with the implantation of anterior chamber lenses (author's transl)].

    abstract::On account of the good results with the new generation of anterior chamber lenses reported by C.D. Binkhorst, the implantation of lenses was begun in 1969 at the Department of Ophthalmology in Bremen and 350 anterior chamber lenses were implanted till 1st Febr. 1977. After the presentation of indications and the opera...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:

    authors: Draeger J,Koudelka A,Modzanowski P

    更新日期:1978-03-01 00:00:00

  • Internal Limiting Membrane Flap Techniques for the Repair of Large Macular Holes: a Short-Term Follow-up of Anatomical and Functional Outcomes.

    abstract::Background To evaluate the technique of inverted internal limiting membrane (ILM) flaps for the management of large macular holes and autologous ILM free flaps for non-closing macular holes. Patients and methods All macular holes were treated with pars plana vitrectomy and dual blue assisted ILM flap technique. The in...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0042-119694

    authors: Guber J,Lang C,Valmaggia C

    更新日期:2017-04-01 00:00:00

  • [Investigations into mucous membrane compatibility using the Endorfer Jod-Thermalsole treatment of the conjunctivae of rabbits (author's transl)].

    abstract::The conjunctivae of nine rabbits of the same breed were used to compare the local compatibility of the Endorfer Jod-Thermalsole with that of a physiological NaCl solution. The neuroleptanalgesics were administered using perfusion techniques. The reddening thus caused was used to measure the degree of inflammation. The...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1055295

    authors: Hirsch E

    更新日期:1981-01-01 00:00:00

  • [Imaging of the Lacrimal Gland and the Lacrimal Drainage System].

    abstract::Die Tränendrüse kann von einer Vielzahl neoplastischer, infektiöser und autoimmunologischer Erkrankungen betroffen sein. Eine radiologische Charakterisierung der Veränderungen kann Hinweise für die differenzialdiagnostische Einordnung liefern. Erkrankungen der ableitenden Tränenwege, insbesondere Tränenwegsverschlüsse...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-0033-1358102

    authors: Pieper CC,Thomas D

    更新日期:2015-03-01 00:00:00

  • [Occlusion of a cilioretinal artery associated with occlusion of the central retinal vein].

    abstract::Cilioretinal artery occlusion (CLRAO) may be occasionally associated with central retinal vein occlusion (CRVO). This combined retinal vascular pathology is described in 5 patients. In this clinical setting the vulnerability of cilioretinal vessels can be explained by the difference in regulatory mechanisms between ch...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045984

    authors: Brazitikos PD,Pournaras CJ,Baumgartner A

    更新日期:1991-05-01 00:00:00

  • [Keratoplasty in private practice].

    abstract::The problems associated with performing penetrating keratoplasty in private practice are briefly discussed: access to an eye bank, high-risk patients, immunosuppressive therapy, complications, and results. One negative aspect is the relatively high incidence (10%) of primary graft failure, but allograft reactions are ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046177

    authors: Witmer R

    更新日期:1990-05-01 00:00:00

  • [Study of blood flow velocity in the central retinal artery using pulsed Doppler sonography].

    abstract::Using the method of pulsed-wave ultrasound-Doppler-Sonography (2 MHz-probe; sample volume 10 mm; variable invading depth by using a so-called "flow-pipe"; transmission range 10 mW/m2), the author demonstrates an objective, reproducible and exact clinical test to examine blood-circulation in central retinal artery. Bec...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045853

    authors: Huismans H

    更新日期:1992-06-01 00:00:00

  • [Intrastromal keratorhexis with the Nd:YAG laser--a possible method of refractive surgery?].

    abstract::A new method of refractive corneal surgery is presented. With the q-switched Nd:YAG-laser Visulas (Zeiss-Oberkochen) we succeed in altering the optical power of the cornea of rabbits, pigs and humans. The number of applied laser spots and the distribution pattern influence the way and the amount of change of refractio...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046315

    authors: Höh H,Becker KW

    更新日期:1990-12-01 00:00:00

  • [Silent sinus syndrome: an unusual cause of vertical diplopia].

    abstract:BACKGROUND:Causes of transient vertical diplopia include myasthenia, dysthyroid orbitopathy, multiple sclerosis, decompensation of a pre-existing state. PURPOSE:To describe an unusual cause of transient diplopia, silent sinus syndrome. METHODS:Clinical, radiological and pathology findings from a 55-year-old man with ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034917

    authors: Durig J,Borruat FX,Jaques B

    更新日期:1998-05-01 00:00:00

  • [Liquid perfluorocarbon in treatment of giant tears].

    abstract::In 20 cases of giant tears with considerable proliferative changes, vitreoretinal silicone-oil-surgery was performed. With liquid perfluorocarbon, the involuted retina could easily be fixed during the operation in its former position without difficulties, before silicone oil as a permanent tamponade was used. The good...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1046078

    authors: Le Mer Y,Kroll P

    更新日期:1991-10-01 00:00:00

  • The Australian Corneal Graft Registry (ACGR).

    abstract::The value of a register of corneal grafts is that it can provide new data about the long-term outcome of corneal transplantation and may allow a more reasoned distribution of scarce donor corneas. The large numbers of cases and events can accommodate wide variations in practice patterns without losing statistical powe...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1045527

    authors: Coster DJ,Williams KA

    更新日期:1994-11-01 00:00:00

  • Effect of soft contact lenses on the measurements of intraocular pressure with non-contact pneumotonometry.

    abstract:PURPOSE:To evaluate the effect of soft contact lenses with different lens power on the measured value of the intraocular pressure with non-contact pneumotonometry. METHODS:120 eyes (80 healthy volunteers: 50 women, 30 men, aged 22 to 61 years) were included in this study. Intraocular pressure was measured with a pneum...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2003-812564

    authors: Schollmayer P,Hawlina M

    更新日期:2003-12-01 00:00:00

  • [The tearing eye in newborn infants and young children: good results with short-term conservative therapy].

    abstract::In this article the authors communicate the results of a short-term conservative treatment for lacrimation in infants with presumed dacryostenosis. The results so far are encouraging and in most cases enable probing of the lacrimal duct to be dispensed with. If the patient fails to respond to the treatment the delay t...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050523

    authors: Bianchetti M,Blumer B

    更新日期:1987-11-01 00:00:00

  • [Measuring the effect of eyeglasses on determination of squint angle with Purkinje reflexes and the prism cover test].

    abstract:BACKGROUND:The alternating prism and cover test is the conventional test for the measurement of the angle of strabismus. The error induced by the prismatic effect of glasses is typically about 27-30%/10 D. Alternatively, the angle of strabismus can be measured with methods based on Purkinje reflex positions. This study...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034870

    authors: Barry JC,Backes A

    更新日期:1998-04-01 00:00:00

  • [Long-term observation of ablatio-prophylaxis with kryopexy (author's transl)].

    abstract::Prophylactic cryo coagulation is especially suitable when there is cloudy media, e.g. blood in the vitreous body or a cataract which would prevent light or laser coagulation. Cryo lesions applied under ophthalmoscopic control are without complication. The paper reviews the 116 eyes collected in 1971 and augments it wi...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Kreissig I,Ruge I

    更新日期:1976-06-01 00:00:00

  • [Assessment of eye damage in private accident insurance in Austria].

    abstract::In Austria, eye damage is assessed by private accident insurance underwriters in accordance with the "General Rules for Private Accident Insurance" (AUVB 1965). According to these rules the degree of invalidity is determined on the basis of three types of findings: 100% in the case of total loss of vision, 30% in the ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1050434

    authors: Lisch K

    更新日期:1987-05-01 00:00:00

  • [Necessary pressure in the ophthalmic artery].

    abstract::As a result of an acute pathologic event ophthalmic arterial pressure may fall below a level necessary to supply sufficient blood to the eye and optic nerve, and thus to preserve full visual function. A sudden partial or even total loss of visual function. A sudden partial or even total loss of vision may follow. In s...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1057432

    authors: Stepanik J

    更新日期:1980-02-01 00:00:00

  • [Surface quality of flexible silicone intraocular lenses. A scanning electron microscopy study].

    abstract:BACKGROUND:Soft intraocular lenses (IOLs) have been developed to be folded during insertion to allow implantation through a small incision. The surface of the IOL is of great importance in postoperative inflammation and long-term acceptance of the implant. Rough and sharp edges can damage delicate intraocular tissues. ...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1035377

    authors: Kohnen T,Magdowski G,Koch DD

    更新日期:1995-10-01 00:00:00

  • [Experimental studies of the significance of the renin-angiotensin system in the retina. A review].

    abstract::BACKGROUND Many peptides now identified in the brain were previously thought of as exclusively peripheral hormones. Among those, the renin-angiotensin system (RAS) is not only found to be of great importance in peripheral vasomotor and electrolyte homeostasis but also acts as neurotransmitter or modulator in the centr...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章,评审

    doi:10.1055/s-2008-1045478

    authors: Jacobi PC,Jurklies B,Kohler K,Zrenner E

    更新日期:1994-06-01 00:00:00

  • [Treatment of retinal detachment with macular hole: scleral buckling with an absorbable fibrin sponge (author's transl)].

    abstract::In 21 patients with macular hole and retinal detachment a macular buckling procedure was performed including diathermic or cryogenic coagulation. An absorbable fibrin sponge (Fibrospum) was used as a new buckling material, which needs not to be sutured to the sclera at the posterior pole. In comparison to other proced...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Wollensak J,Engels T

    更新日期:1977-08-01 00:00:00

  • [The judgement of the degree of disability in cases of aphakia and pseudoaphakia (author's transl)].

    abstract::Since more than 40 years the judgement of the degree of disability in cases of unilateral aphakia is discussed. This means the effort toward an advisory objectivity on the one hand and human understanding for the patient's damage on the other hand. It is supposed to repeal the 4th emergency ordinance of 1932 and to pa...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:

    authors: Mewe L,Promesberger HW

    更新日期:1979-07-01 00:00:00

  • [Acute reversible night blindness caused by vitamin A deficiency in pancreatic carcinoma].

    abstract:BACKGROUND:Vitamin A deficiency is a leading cause of blindness in childhood in the developing countries. In developed countries xerophthalmia occurs mainly as secondary hypovitaminosis due to malabsorption in chronic alcoholism or intestinal disorders. PATIENT AND METHODS:A 24-year-old female patient complained of ni...

    journal_title:Klinische Monatsblatter fur Augenheilkunde

    pub_type: 杂志文章

    doi:10.1055/s-2008-1034956

    authors: Schönherr U

    更新日期:1998-08-01 00:00:00