Secondary angiosarcoma: A fatal complication of chronic lymphedema.

Abstract:

:Secondary Angiosarcoma (Stewart-Treves Syndrome) is a rare malignant cutaneous lesion, which arises in chronic lymphedema of the extremity, often observed after breast cancer treatment. We reviewed the history and the oncological outcome of two patients with this disease. Multimodal therapy including hyperthermic isolated limb perfusion with TNF-alpha and Melphalan, combined with radical resection of the affected skin and subcutaneous tissue including the fascia, with large safety margins may probably lead to better survival.

journal_name

J Surg Oncol

authors

Farzaliyev F,Hamacher R,Steinau Professor HU,Bertram S,Podleska LE

doi

10.1002/jso.25598

subject

Has Abstract

pub_date

2020-01-01 00:00:00

pages

85-90

issue

1

eissn

0022-4790

issn

1096-9098

journal_volume

121

pub_type

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