Differential immune response of congenic mice to ultraviolet-treated major histocompatibility complex class II-incompatible skin grafts.

abstract：:Second clinical kidney grafts often survive longer than first grafts. Using a rat cardiac allograft model, we examined the conditions under which survival of a second graft can be longer than first graft survival. In the BUF-to-LEW combination, following rejection of the first transplant, second cardiac allografts fro...

journal_title：Transplantation

authors： Yanagiya A,Terasaki PI,Iwaki Y,Ho BB,Drinkwater DC,Laks H

更新日期：1992-10-01 00:00:00

abstract：BACKGROUND:Graft coronary arteriosclerosis (GCA) is the major limiting factor for long-term survival after heart transplantation. In this study, we investigated the effect of Multiglycosidorum tripterygii (MT) on GCA and platelet-derived growth factor A (PDGF-A) mRNA expression of transplanted hearts. METHODS:Two grou...

journal_title：Transplantation

authors： Hachida M,Zhang XL,Lu H,Hoshi H,Koyanagi H

更新日期：1998-06-15 00:00:00

abstract：:T cells play an important role in protective immunity against tuberculosis. As patients are not reimmunized with BCG after BMT, the question arises as to whether PPD-specific memory T cells are transferred from the marrow donor to the recipient and persist in the long-term. We studied long-term survivors of non-T cell...

journal_title：Transplantation

authors： Rouleau M,Senik A,Leroy E,Vernant JP

更新日期：1993-01-01 00:00:00

abstract：:Cyclosporine extends kidney allograft survival in the chacma baboon, and this study explores various administration protocols to generate optimal serum concentrations of the drug, assessed by radioimmunoassay and by inhibition of lymphocyte transformation by phytohemagglutinin and allogeneic lymphocytes in culture. Se...

journal_title：Transplantation

authors： Smit JA,Drielsma RF,Myburgh JA,Laupacis A,Stiller CR

更新日期：1983-08-01 00:00:00

abstract：BACKGROUND:Kidneys from older donors are likely to have a lower nephron mass. Nevertheless they constitute a valuable source of kidney allografts. Long cold ischemic time (CIT), with or without delayed graft function (DGF), has been associated with reduced graft survival. The aim of this study was to review the experie...

journal_title：Transplantation

authors： Asderakis A,Dyer P,Augustine T,Worthington J,Campbell B,Johnson RW

更新日期：2001-08-27 00:00:00

abstract：BACKGROUND:It is imperative for healthcare providers to examine Western Muslim attitudes on organ donation, because they are reluctant donors. We explored such opinion with the aid of a quantitative survey. METHODS:Voluntary completion of an anonymous survey was promoted (online and paper sampling). For a population t...

journal_title：Transplantation

authors： Sharif A,Jawad H,Nightingale P,Hodson J,Lipkin G,Cockwell P,Ball S,Borrows R

更新日期：2011-11-27 00:00:00

abstract：:Temperature is a key parameter in organ preservation that has been consistently linked to primary nonfunction (PNF). In this communication, and for the first time anywhere, continued and direct measurements of human liver intraparenchymal temperatures are reported in six clinical cases of orthotopic liver transplantat...

journal_title：Transplantation

authors： Villa R,Fondevila C,Erill I,Guimerà A,Bombuy E,Gómez-Suárez C,Sacristán JC,García-Valdecasas JC

更新日期：2006-02-15 00:00:00

abstract：BACKGROUND:To better understand how different histologic patterns of allograft inflammation found on biopsies of human cardiac allografts progress to high-grade rejection, we undertook a statistical analysis of our institutional database to detect statistical patterns among different types of myocardial allograft infla...

journal_title：Transplantation

authors： Smith RN,Chang Y,Houser S,Dec GW,Grazette L

更新日期：2002-06-27 00:00:00

abstract：BACKGROUND:Epitopes are the sites to which antibodies bind. Both alpha and beta peptide chains of the human leukocyte antigen-DQ heterodimers (DQA1 and DQB1, respectively) contain polymorphic regions. We can identify DQA1 and DQB1 epitopes by DQ single antigen beads assay of the antibodies, correlating the beads' react...

journal_title：Transplantation

authors： Deng CT,El-Awar N,Ozawa M,Cai J,Lachmann N,Terasaki PI

更新日期：2008-08-15 00:00:00

abstract：:Governmental and private programs that pay next of kin who give permission for the removal of their deceased relative's organs for transplantation exist in a number of countries. Such payments, which may be given to the relatives or paid directly for funeral expenses or hospital bills unrelated to being a donor, aim t...

journal_title：Transplantation

authors： Capron AM,Delmonico FL,Dominguez-Gil B,Martin DE,Danovitch GM,Chapman J

更新日期：2016-09-01 00:00:00

abstract：BACKGROUND:Intrapulmonary arteriovenous shunting (IPS), occasionally associated with advanced liver disease, may reverse after liver transplantation (LTx). Two-dimensional contrast-enhanced echocardiography, a convenient noninvasive study, has never been used to demonstrate disappearance of IPS after LTx. METHODS:For ...

journal_title：Transplantation

authors： Hasegawa T,Kamiyama M,Azuma T,Sasaki T,Okada A,Miwatani T,Matsushita T

更新日期：2000-02-27 00:00:00

abstract：:Pulmonary endothelium is considered the compartment most susceptible to preservation damage. This investigation was designed to analyze the efficacy of an original, University of Parma low-potassium-albumin solution (SPAL UP) on cultured human pulmonary artery endothelial cells (HPAEC) and to compare its effects with ...

journal_title：Transplantation

authors： Spaggiari L,Rusca M,Carbognani P,Alfieri R,Urbani S,Cattelani L,Petronini P,Solli P,Borghetti AF,Bobbio P

更新日期：1996-11-15 00:00:00

abstract：BACKGROUND:Kidney donation after cardiac death leads to vascular damage as a result of warm ischemia, affecting renovascular circulating volume. Novel ultrasound dilution techniques may be used to measure renovascular circulating volumes during hypothermic machine perfusion of donor kidneys. METHODS:Renovascular circu...

journal_title：Transplantation

authors： de Vries EE,van Smaalen TC,Boer J,Hoogland ER,Krivitski NM,Snoeijs MG,van Heurn LW

更新日期：2013-05-15 00:00:00

abstract：BACKGROUND:This study evaluates whether surgical strategies such as the portosystemic shunt and ischemic preconditioning can protect against hepatic and pulmonary injury associated with liver transplantation. METHODS:The effect of the portosystemic shunt, ischemic preconditioning, and both surgical procedures together...

journal_title：Transplantation

authors： Fernández L,Heredia N,Peralta C,Xaus C,Roselló-Catafau J,Rimola A,Marco A,Serafín A,Deulofeu R,Gelpí E,Grande L

更新日期：2003-07-27 00:00:00

abstract：:Monocytes play a crucial role in the response of lymphocytes to phytomitogens. This role is evident during the very early events after exposure to the mitogen. Thus, significant lymphocyte transformation does occur when monocytes are removed from the culture within a few hours after exposure to mitogen, and the presen...

journal_title：Transplantation

authors： Mookerjee BK,Ballard J

更新日期：1979-01-01 00:00:00

abstract：:A laparoscopic live-donor nephrectomy was performed on a 40-year-old man. The kidney was removed intact via a 9-cm infraumbilical midline incision. Warm ischemia was limited to less than 5 min. Immediately upon revascularization, the allograft produced urine. By the second postoperative day, the recipient's serum crea...

journal_title：Transplantation

authors： Ratner LE,Ciseck LJ,Moore RG,Cigarroa FG,Kaufman HS,Kavoussi LR

更新日期：1995-11-15 00:00:00

abstract：BACKGROUND:The clinical significance of HLA-directed antibodies newly detected after transplantation (HT) is controversial. METHODS:Seventy-one HT recipients consented to enroll. Mean follow-up time was 28 months (range 6-48). Panel reactive antibody (PRA) analysis was performed on posttransplant sera (2 weeks, 1, 2, ...

journal_title：Transplantation

authors： Tambur AR,Pamboukian SV,Costanzo MR,Herrera ND,Dunlap S,Montpetit M,Heroux A

更新日期：2005-10-27 00:00:00

abstract：BACKGROUND:In an effort to define reliable assays that might predict postimmunosuppressant-withdrawal development of chronic rejection (CR), despite conditioning for tolerance induction, we evaluated various immunological responses in nonhuman primate renal allograft recipients. METHODS:Fourteen Cynomolgus monkeys rec...

journal_title：Transplantation

authors： Boskovic S,Kawai T,Smith RN,Wee SL,Nadazdin O,Koyama I,Saidman S,Cardarelli F,Elias N,Sykes M,Strom T,Colvin RB,Sachs DH,Cosimi AB

更新日期：2006-09-27 00:00:00

abstract：:The early detection of allograft rejection remains elusive after solitary pancreas transplantation (PTX). We have previously described a modified technique of cystoscopic transduodenal PTX biopsy using the Biopty gun under ultrasound guidance. During the last 2 years, we performed 24 solitary PTXs with prospective pro...

journal_title：Transplantation

authors： Stratta RJ,Taylor RJ,Grune MT,Sindhi R,Sudan D,Castaldo P,Cushing KA,Radio SJ,Wisecarver JL,Matamoros A

更新日期：1995-12-27 00:00:00

abstract：BACKGROUND:Ischemia-reperfusion syndrome has been recognized as an important pathogenic factor in renal transplantation, not only in the development of delayed graft function but also in the development of acute and chronic rejection. Hypoxia-inducible factor (HIF)-1 activates transcription of several genes implicated ...

journal_title：Transplantation

authors： Lario S,Mendes D,Bescós M,Iñigo P,Campos B,Alvarez R,Alcaraz A,Rivera-Fillat F,Campistol JM

更新日期：2003-05-27 00:00:00

abstract：BACKGROUND:During the isolation process, pancreatic islets are exposed to an environment of sterile inflammation resulting in an upregulated inflammatory state before transplantation. Toll-like receptor 4 (TLR4) has been identified as a major mediator of sterile inflammation. Therefore, we sought to determine whether e...

journal_title：Transplantation

authors： Chang CA,Murphy K,Kane RR,Lawrence MC,Naziruddin B

更新日期：2018-09-01 00:00:00

abstract：:Flow cytometry (FC) is increasingly being used as a crossmatch procedure in addition to the standard complement-dependent cytotoxicity (CDC) test. In fact, FC offers a number of advantages over CDC and has the potential to become the primary crossmatch technique for cadaveric donor renal transplantation. We evaluated ...

journal_title：Transplantation

authors： Scornik JC,Brunson ME,Schaub B,Howard RJ,Pfaff WW

更新日期：1994-02-27 00:00:00

abstract：:In vitro pretreatment of islets of Langerhans with deoxyguanosine (dGuo) has been shown to be effective for the prolongation of islet allograft survival in rats. [This study evaluates the effect of pretreatment of islets with dGuo transplanted into CsA-treated recipients.] Transplantation of dGuo-treated islets from W...

journal_title：Transplantation

authors： al-Abdullah IH,Kumar AM,al-Adnani MS,Abouna GM

更新日期：1991-05-01 00:00:00

abstract：BACKGROUND:Cardiac allograft vasculopathy (CAV) has an incidence of 43% at 8 years after heart transplantation with extremely limited treatment options and unclear pathogenesis. CAV constitutes a significant complication that limits the long-term survival of heart recipients. Insulin-like growth factor-1 (IGF-1) is ass...

journal_title：Transplantation

authors： Aharinejad S,Salama M,Rödler S,Ehrlich M,Zuckermann A,Laufer G

更新日期：2012-02-15 00:00:00

abstract：BACKGROUND:T lymphocyte activation mediated by CD28 costimulation plays a critical role in graft rejection. Plant alkaloid tetrandrine, purified from a Chinese antirheumatic herb, is a potent immunosuppressant. Here, we examined its effects on several CD28-costimulated T-cell activities. In addition, such effects were ...

journal_title：Transplantation

authors： Lai JH,Ho LJ,Kwan CY,Chang DM,Lee TC

更新日期：1999-11-15 00:00:00

abstract：BACKGROUND:Long-term survival and functions of encapsulated islet grafts need to be evaluated in the absence of immunosuppression. The present study aimed to assess the viability and functions of macroencapsulated islets grafted in nonhuman primates without immunosuppression for 1 year. METHODS:Islet transplantations ...

journal_title：Transplantation

authors： Sasikala M,Rao GV,Vijayalakshmi V,Pradeep R,Pothani S,Kumar PP,Gaddipati R,Sirisha G,Cheemalakonda R,Tandan M,Subramanyam C,Vasudevan S,Reddy DN

更新日期：2013-10-15 00:00:00

abstract：BACKGROUND:For cyclosporine (CsA), 2-hr postdose level (C2) is the best single time point predictor of the area under the curve and a critical measure for effective dosing. The therapeutic CsA microemulsion (Neoral) C2 range in de novo heart transplant patients remains to be determined. PURPOSE:The purpose of this stu...

journal_title：Transplantation

authors： Cantarovich M,Ross H,Arizón JM,Gómez MA,Straatman L,Orús J,Alonso-Pulpón L,Molina BD,Wang S,Lage E,Crespo MG,Manito N,Howlett J,Haddad H,Motown Study Group.

更新日期：2008-04-15 00:00:00

abstract：:Frozen sections of lymph nodes from normal mice were examined by immunofluorescence with anti-T lymphocyte and anti-Ig reagents and by autoradiography following [3H]TdR administration. The scattered T lymphocytes present among B lymphocytes of primary follicles were found to be mostly nonproliferating; the few prolife...

journal_title：Transplantation

authors： Berman MA,Rafiei S,Gutman GA

更新日期：1981-11-01 00:00:00

abstract：:The length of time after syngeneic bone marrow reconstitution when tolerance to alloantigens can be induced in adult mice during T cell differentiation from bone marrow cells was studied by exposing those T cells to (recipient x donor)F1 spleen cells. Supralethally irradiated C3H/He Slc(C3H; H-2k) mice were reconstitu...

journal_title：Transplantation

authors： Tomita Y,Himeno K,Mayumi H,Tokuda N,Nomoto K

更新日期：1989-06-01 00:00:00

abstract：BACKGROUND:The authors studied the relationship between the dynamics of Epstein-Barr virus (EBV) load, CD8 T-cell activation and differentiation, and EBV-associated symptoms in 25 children after kidney transplantation (Tx). METHODS:Twenty-two patients were enrolled at the time of Tx and three at diagnosis of EBV-induc...

journal_title：Transplantation

authors： Baudouin V,Dehée A,Pédron-Grossetete B,Ansart-Pirenne H,Haddad E,Maisin A,Loirat C,Sterkers G

更新日期：2004-06-15 00:00:00