Risk of cervical and vaginal dysplasia after surgery for vulvar intraepithelial neoplasia or cancer: A 6 year follow-up study.

abstract：:In an attempt to establish a blood-based biochemical index for diagnosis of cervical cancer and treatment monitoring of patients suffering from the disease, serum levels of total sialic acid (TSA), lipid-bound sialic acid (LSA), and lactate dehydrogenase were estimated by highly specific spectrophotometric methods. Se...

journal_title：Gynecologic oncology

authors： Patel PS,Rawal GN,Balar DB

更新日期：1993-09-01 00:00:00

abstract：BACKGROUND:Ovarium cancer is the fifth most common cause of cancer-related death in women and is the most common fatal gynecologic malignancy. So far, ovarium carcinoma has not been reported to have occurred in female-to-male transsexuals. OBJECTIVE AND METHOD:We report on two such cases. Long-term exposure to increas...

journal_title：Gynecologic oncology

authors： Hage JJ,Dekker JJ,Karim RB,Verheijen RH,Bloemena E

更新日期：2000-03-01 00:00:00

abstract：:The existing means of detecting recurrent ovarian carcinoma are notoriously poor. Positron emission tomography (PET) is a form of computer-assisted imaging which produces images reflective of the biochemistry of the tissues rather than their physical characteristics. PET imaging with the positron emitting glucose anal...

journal_title：Gynecologic oncology

authors： Karlan BY,Hawkins R,Hoh C,Lee M,Tse N,Cane P,Glaspy J

更新日期：1993-11-01 00:00:00

abstract：OBJECTIVE:The objective of this study was to evaluate the impact of introducing HR-HPV testing in cytology regarding cervical cancer screening practice. METHODS:A pooled analysis of liquid-based cytology (LBC) and HR-HPV testing using data from 13 population-based cervical cancer screening studies conducted in China w...

journal_title：Gynecologic oncology

authors： Pan QJ,Hu SY,Guo HQ,Zhang WH,Zhang X,Chen W,Cao J,Jiang Y,Zhao FH,Qiao YL

更新日期：2014-05-01 00:00:00

abstract：:Between 1965 and 1988, 125 patients with primary invasive vaginal carcinoma were treated with radiation therapy at the Center of Oncology in Kraków. Twenty-two superficial stage I patients received radium or cesium intracavitary radiation alone. The remaining 11 patients with stage I disease whose lesions were either ...

journal_title：Gynecologic oncology

authors： Urbański K,Kojs Z,Reinfuss M,Fabisiak W

更新日期：1996-01-01 00:00:00

abstract：OBJECTIVE:Ovarian cancer is the leading cause of death in women with gynecologic cancer. CA125 is the commonly used biomarker in the diagnosis of ovarian cancer, but has limitations in both sensitivity and specificity. Human Epididymal secretory protein (HE4) is a promising biomarker and is included in the Risk of Ovar...

journal_title：Gynecologic oncology

authors： Stiekema A,Lok CA,Kenter GG,van Driel WJ,Vincent AD,Korse CM

更新日期：2014-03-01 00:00:00

abstract：:Sialosyl-Tn (S-Tn) antigen, a cancer-related antigen, was expressed in 56.3% (36 of 64 cases) of the common epithelial carcinoma tissues. This antigen was moderately to strongly expressed in 83.3% (15 of 18 cases) of the mucinous adenocarcinomas. In contrast, it was weakly expressed in 31.3% (5 of 16 cases) of the ser...

journal_title：Gynecologic oncology

authors： Ryuko K,Iwanari O,Kitao M,Moriwaki S

更新日期：1993-05-01 00:00:00

abstract：OBJECTIVE:To compare the efficacy between acupuncture and ondansetron in the prevention of delayed chemotherapy induced nausea and vomiting (CINV). METHODS:70 patients were randomized to receive either 1) acupuncture at P6 point before chemotherapy infusion or 2) ondansetron 8 mg intravenously 30 min before chemothera...

journal_title：Gynecologic oncology

authors： Rithirangsriroj K,Manchana T,Akkayagorn L

更新日期：2015-01-01 00:00:00

abstract：:The pelvis is the predominant site of failure following radical radiotherapy (RT) for locally advanced cervical cancer. We report the results of phase I-II studies on 200 patients with bulky (greater than or equal to 5 cm) carcinoma of the cervix. Patients were treated between 1981 and 1988 on sequential protocols of ...

journal_title：Gynecologic oncology

authors： Thomas G,Dembo A,Fyles A,Gadalla T,Beale F,Bean H,Pringle J,Rawlings G,Bush R,Black B

更新日期：1990-09-01 00:00:00

abstract：:Verrucous carcinoma (VC) of the female genital tract is a rare lesion, primarily affecting postmenopausal women. A case of VC of the vulva is reported, bringing the total number of VC of the female genital tract to 89. VC is a slowly growing, locally "pushing" tumor with a rather benign histologic appearance, and the ...

journal_title：Gynecologic oncology

authors： Andersen ES,Sorensen IM

更新日期：1988-07-01 00:00:00

abstract：OBJECTIVES:CD4(+)CD25(+) regulatory T-cells (Tregs), that express the transcription factor FOXP3, suppress effector T-cell populations and can enable tumour cells to evade the host immune response. In this study, we investigated the numbers of FOXP3(+) Tregs in the normal and malignat endometrium and examined potential...

journal_title：Gynecologic oncology

authors： Giatromanolaki A,Bates GJ,Koukourakis MI,Sivridis E,Gatter KC,Harris AL,Banham AH

更新日期：2008-08-01 00:00:00

abstract：:Clinical research in gynecologic oncology has seen a proliferation of studies that investigate the effectiveness of treatments using existing data sources such as cancer registries, electronic health records, and insurance claims. These observational studies are often feasible when randomized trial may not be, and may...

journal_title：Gynecologic oncology

authors： Moss HA,Melamed A,Wright JD

更新日期：2019-03-01 00:00:00

abstract：:During the period 1977 to 1985, 12 patients with FIGO stage II and III epithelial ovarian carcinoma failed to achieve a pathologic complete response with chemotherapy and underwent salvage whole-abdominal irradiation (WAXRT). Six of these patients had gross residual disease present at the time of irradiation, and thre...

journal_title：Gynecologic oncology

authors： Linstadt DE,Stern JL,Quivey JM,Leibel SA,Lacey CG

更新日期：1990-03-01 00:00:00

abstract：BACKGROUND:We attempted to determine the prevalence of genital human papillomavirus (HPV) infection in women attending gynecologic practitioners in South Taiwan. METHODS:The population included 4383 women aged 16-78 seeking HPV testing at primary gynecologic practitioners regardless of their cervical cytology results....

journal_title：Gynecologic oncology

authors： Lin H,Ma YY,Moh JS,Ou YC,Shen SY,ChangChien CC

更新日期：2006-04-01 00:00:00

abstract：OBJECTIVE:Although the relationship between human papilloma virus (HPV) and cervical cancer is well established, the prognostic value of HPV status has not been determined, largely because previous studies have yielded conflicting results. This study aimed to investigate the prognostic value of pre-treatment HPV DNA fo...

journal_title：Gynecologic oncology

authors： Chong GO,Lee YH,Han HS,Lee HJ,Park JY,Hong DG,Lee YS,Cho YL

更新日期：2018-01-01 00:00:00

abstract：BACKGROUND:Recurrence of endometrial cancer in the brain is a rare event generally accompanied by limited life expectancy. We present an unusual case of long-term survival following surgical resection of an intracranial endometrial cancer metastasis. CASE:The present case is a patient with FIGO stage IIB, grade III en...

journal_title：Gynecologic oncology

authors： Elliott KS,Borowsky ME,Lee YC,Rao C,Abulafia O

更新日期：2004-10-01 00:00:00

abstract：BACKGROUND:The role of radiotherapy for recurrent or residual granulosa cell tumor of the ovary (GCTO) is controversial. One reason for this controversy may be that most published studies on this topic have not utilized sectional imaging to assess response to radiotherapy. We report on three cases of recurrent or resid...

journal_title：Gynecologic oncology

authors： E C,Samant R,Fung MF,Le T,Hopkins L,Senterman M

更新日期：2006-08-01 00:00:00

abstract：BACKGROUND:Herpes gestationis (HG) is a rare, recurrent, pruritic, vesicobullous dermatosis occurring predominantly in pregnancy and seldom in early puerperium. Reports of the association of HG with choriocarcinoma are extremely rare and this case highlights such a possible link. CASE:This case focuses on the late pos...

journal_title：Gynecologic oncology

authors： Djahansouzi S,Nestle-Kraemling C,Dall P,Bender HG,Hanstein B

更新日期：2003-05-01 00:00:00

abstract：OBJECTIVE:To prospectively evaluate tumor control, survival, and toxic effects in patients with International Federation of Gynecology and Obstetrics (1988) stage I-IIIA papillary serous carcinoma of the endometrium treated with concurrent chemoradiation and adjuvant chemotherapy. METHODS:Thirty-two patients were enro...

journal_title：Gynecologic oncology

authors： Jhingran A,Ramondetta LM,Bodurka DC,Slomovitz BM,Brown J,Levy LB,Garcia ME,Eifel PJ,Lu KH,Burke TW

更新日期：2013-05-01 00:00:00

abstract：BACKGROUND:According to current treatment guidelines, comprehensive surgical staging procedures in endometrial cancer confined to the uterus depend on uterine risk factors: a systematic lymph node dissection (LND) is recommended in high risk patients and should be omitted in low risk patients. Its role in intermediate ...

journal_title：Gynecologic oncology

authors： Pölcher M,Rottmann M,Brugger S,Mahner S,Dannecker C,Kiechle M,Brambs C,Grab D,Anthuber C,von Koch F,Schnelzer A,Engel J

更新日期：2019-07-01 00:00:00

abstract：:Twenty-three evaluable patients with refractory epithelial ovarian cancer were treated with bisantrene (CL216,942). The drug was given as a single-dose injection every 3 weeks. One patient (4%) showed a partial response. The compound thus has limited activity against this malignancy. ...

journal_title：Gynecologic oncology

authors： Kavanagh JJ,Gershenson DM,Saul PB,Copeland LJ

更新日期：1986-01-01 00:00:00

abstract：OBJECTIVE:There are currently limited published data available on the safety and feasibility of the prolonged administration of paclitaxel. The goal of this study was to review the cumulative toxicity associated with the continuous long-term administration of this agent to women with gynecologic cancers. METHODS:Eleve...

journal_title：Gynecologic oncology

authors： Rohl J,Kushner D,Markman M

更新日期：2001-05-01 00:00:00

abstract：OBJECTIVE:Aberrant expression of HER2/neu and PIK3CA gene products secondary to amplification/mutations are common in high-grade-serous-endometrial (USC) and ovarian-cancers (HGSOC). Because scant information is currently available in the literature on the potential negative effect of PIK3CA mutations on the activity o...

journal_title：Gynecologic oncology

authors： Bonazzoli E,Cocco E,Lopez S,Bellone S,Zammataro L,Bianchi A,Manzano A,Yadav G,Manara P,Perrone E,Haines K,Espinal M,Dugan K,Menderes G,Altwerger G,Han C,Zeybek B,Litkouhi B,Ratner E,Silasi DA,Huang GS,Azodi M,

更新日期：2019-04-01 00:00:00

abstract：:Primary adenocarcinoma of the vulva is rare, and cloagocenic adenocarcinoma of the vulva is extremely rare. Here we report a vulvar tumor characterized by columnar cells with prominent brush border and the presence of goblet cells and endocrine cells, presenting the tubulovillous pattern and mucin histochemistry of en...

journal_title：Gynecologic oncology

authors： Willén R,Békássy,Carlén B,Bozoky B,Cajander S

更新日期：1999-08-01 00:00:00

abstract：OBJECTIVE:To evaluate safety, tolerability, and antitumor activity of pembrolizumab monotherapy in patients with programmed death ligand 1 (PD-L1)-expressing advanced ovarian cancer enrolled in the multicohort, phase Ib KEYNOTE-028 trial. METHODS:Key inclusion criteria were age ≥18 years; advanced ovarian epithelial, ...

journal_title：Gynecologic oncology

authors： Varga A,Piha-Paul S,Ott PA,Mehnert JM,Berton-Rigaud D,Morosky A,Yang P,Ruman J,Matei D

更新日期：2019-02-01 00:00:00

abstract：:Survival rates were computed for 376 women diagnosed with carcinoma of the uterine cervix between 1964 and 1988. The 5-year survival rate for the entire group was 63%. The effect of age at diagnosis, clinical stage, histopathology, year of diagnosis, and screening program attendance was studied by univariate analysis ...

journal_title：Gynecologic oncology

authors： Sigurdsson K,Hrafnkelsson J,Geirsson G,Gudmundsson J,Salvarsdóttir A

更新日期：1991-10-01 00:00:00

abstract：OBJECTIVE:To conduct a systematic review of the literature regarding the systemic treatment of advanced uterine sarcoma and provide an evidence-based summary of the available literature. METHODS:MEDLINE, EMBASE, and the Cochrane Library databases were searched. "Uterine sarcoma," "leiomyosarcoma," "mixed mesodermal tu...

journal_title：Gynecologic oncology

authors： Kanjeekal S,Chambers A,Fung MF,Verma S

更新日期：2005-05-01 00:00:00

abstract：BACKGROUND:Post-irradiation breast sarcoma is a rare and highly aggressive tumor, associated with poor prognosis. However, the mean latent periods reported for postradiation sarcomas after treatment of breast cancer ranges from 5 to 10 years. CASE:We present a rare case of fibrosarcoma of the axilla, diagnosed 23 mont...

journal_title：Gynecologic oncology

authors： Plotti F,Di Donato V,Zullo MA,Angioli R,Panici PB

更新日期：2006-12-01 00:00:00

abstract：OBJECTIVE:Management of locally advanced cervical cancer consists primarily of combination external and internal radiation. In order to investigate the impact of intracavitary brachytherapy versus interstitial brachytherapy on local tumor control, survival, and complications, we retrospectively reviewed the concomitant...

journal_title：Gynecologic oncology

authors： Monk BJ,Tewari K,Burger RA,Johnson MT,Montz FJ,Berman ML

更新日期：1997-12-01 00:00:00

abstract：:Sizes of the largest metastatic nodes were evaluated as a prognostic factor in 152 patients with Stage IB to IIB cervical carcinomas treated by radical hysterectomy and postoperative irradiation. Of the 152 cases, the largest positive nodes were less than 10 mm in 24 (16%), 10-20 mm in 74 (49%), greater than or equal ...

journal_title：Gynecologic oncology

authors： Inoue T,Chihara T,Morita K

更新日期：1984-10-01 00:00:00