Importance of serum sialic acid and lactate dehydrogenase in diagnosis and treatment monitoring of cervical cancer patients.

abstract：OBJECTIVE:Human papillomavirus (HPV) infection is the primary cause of cervical cancer. HPV-mediated immune alterations are known to play crucial roles in determining viral persistence and host cell transformation. We sought to thoroughly understand HPV-directed immune alterations in cervical cancer by exploring public...

journal_title：Gynecologic oncology

authors： Chen L,Luan S,Xia B,Liu Y,Gao Y,Yu H,Mu Q,Zhang P,Zhang W,Zhang S,Wei G,Yang M,Li K

更新日期：2018-05-01 00:00:00

abstract：OBJECTIVE:This article critically reviews the literature on the association between endometriosis and gynecological cancers and breast cancer, based on epidemiologic data. METHODS:Literature review of the English language literature based on searching in the MEDLINE (PubMed) database and additional collection of repor...

journal_title：Gynecologic oncology

authors： Munksgaard PS,Blaakaer J

更新日期：2011-10-01 00:00:00

abstract：OBJECTIVE:To correlate findings on pathologic examination of loop electroexcisional procedure (LEEP) or cone biopsy specimens with residual disease in radical hysterectomy specimens in patients with stage IA2 cervical cancer to determine whether a subset of such patients may be eligible for conservative, fertility-spar...

journal_title：Gynecologic oncology

authors： Suri A,Frumovitz M,Milam MR,dos Reis R,Ramirez PT

更新日期：2009-01-01 00:00:00

abstract：OBJECTIVE:The objective was to describe trends over time in key factors surrounding end-of-life care on a gynecologic oncology service at a tertiary cancer center. METHODS:Patients with gynecologic cancers who were hospitalized and died at our institution between 1992 and 1997 were identified using institutional datab...

journal_title：Gynecologic oncology

authors： Dalrymple JL,Levenback C,Wolf JK,Bodurka DC,Garcia M,Gershenson DM

更新日期：2002-05-01 00:00:00

abstract：OBJECTIVES:The aim of this study was to assess the safety, efficacy and impact on survival of low anterior resection and primary anastomosis at the time of en bloc resection for primary and recurrent epithelial ovarian carcinoma. METHODS:We performed a retrospective review of 46 primary and 14 recurrent epithelial ova...

journal_title：Gynecologic oncology

authors： Park JY,Seo SS,Kang S,Lee KB,Lim SY,Choi HS,Park SY

更新日期：2006-12-01 00:00:00

abstract：:Adenocarcinoma of the urethra is a rare neoplasm which is believed to arise from the periurethral ducts. Four such cases have been diagnosed at our institution during the past 25 years and their clinical courses are summarized in this report. In one patient, a disseminated coagulopathy with a predominantly fibrinolyti...

journal_title：Gynecologic oncology

authors： Taylor RN,Lacey CG,Shuman MA

更新日期：1985-10-01 00:00:00

abstract：OBJECTIVE:In a previous study using the same cases of squamous cervical neoplasia and microinvasive carcinoma (MICA) we found an association between FHIT gene deletion and infection with high-risk HPV (HR HPV). The purpose of this study was to evaluate Fhit protein expression by immunohistochemistry in order to determi...

journal_title：Gynecologic oncology

authors： Butler D,Collins C,Mabruk M,Leader MB,Kay EW

更新日期：2002-08-01 00:00:00

abstract：:Hypersensitivity reactions to intravenous administration of carboplatin (CP) have been previously reported. However, hypersensitivity reaction to intraperitoneal administration of CP has not yet been reported. A 66-year-old woman diagnosed with ovarian carcinoma underwent six courses of intraperitoneal administration ...

journal_title：Gynecologic oncology

authors： Shukunami K,Kurokawa T,Kawakami Y,Kubo M,Kotsuji F

更新日期：1999-03-01 00:00:00

abstract：OBJECTIVES:We assessed the efficacy and toxicity of once-weekly topotecan (Hycamtin; GlaxoSmithKline) for relapsed or persistent epithelial ovarian cancer (EOC) and primary peritoneal carcinoma (PPC). METHODS:Patients with recurrent or persistent EOC and PPC previously treated with > or = 1 course of platinum-based ch...

journal_title：Gynecologic oncology

authors： Safra T,Menczer J,Bernstein R,Shpigel S,Inbar MJ,Grisaru D,Golan A,Levy T

更新日期：2007-04-01 00:00:00

abstract：:In a study of 73 patients, diagnosed with recurrent squamous cell carcinoma of the vulva between 1975 and 1990, the effect of clinical variables on the outcome was evaluated. The overall 5-year survival rate was 35.2%. Of the 73 patients, 33 (45.2%) originally had Stage I or II disease and 40 (54.8%) Stage III or IVA;...

journal_title：Gynecologic oncology

authors： Piura B,Masotina A,Murdoch J,Lopes A,Morgan P,Monaghan J

更新日期：1993-02-01 00:00:00

abstract：:Uterine leiomyosarcoma is the most common type of uterine sarcoma. It is an extremely aggressive malignancy associated with a poor overall prognosis. Women affected may vary in age, but are most often diagnosed in their perimenopausal years. Presenting symptoms may be vague and mimic other benign uterine conditions. P...

journal_title：Gynecologic oncology

authors： Roberts ME,Aynardi JT,Chu CS

更新日期：2018-12-01 00:00:00

abstract：OBJECTIVE:The aim of this study was to determine the utility of DNA flow cytometry as a prognostic indicator for risk of recurrence and overall survival in patients with early stage adenocarcinomas of the uterine cervix. METHODS:DNA flow cytometry was performed to determine ploidy, DNA index, and proliferative index i...

journal_title：Gynecologic oncology

authors： Magtibay PM,Perrone JF,Stanhope CR,Katzmann JA,Keeney GL,Li H

更新日期：1999-11-01 00:00:00

abstract：:We have previously reported an overall response rate of 41% and a median survival duration of 14 months in a series of 49 patients with metastatic or recurrent endometrial carcinoma treated by a combination of etoposide, 5-fluorouracil, and cisplatin. In order to increase response rate and survival duration, doxorubic...

journal_title：Gynecologic oncology

authors： Pierga JY,Diéras V,Beuzeboc P,Dorval T,Palangié T,Jouve M,Scholl SM,Garcia-Giralt E,Pouillart P

更新日期：1997-08-01 00:00:00

abstract：PURPOSE:This report describes the strength and significance of the association between antecedent and mediating variables across four categories of quality of life (QOL) outcomes in 132 disease free women with ovarian germ cell survivors. METHODS:Survivors (n=132) participated in a mailed questionnaire and computer-as...

journal_title：Gynecologic oncology

authors： Champion V,Williams SD,Miller A,Reuille KM,Wagler-Ziner K,Monahan PO,Zhao Q,Gershenson D,Cella D,Gynecologic Oncology Group.

更新日期：2007-06-01 00:00:00

abstract：OBJECTIVES:To report the intermediate-term results of trans-abdominal ultrasound (TAUS)-guided brachytherapy in cervical cancer. MATERIALS AND METHODS:Ninety-two patients with cervical cancer (stage IB-IVA, according to FIGO staging), were treated by curative radiotherapy from February 2012 to June 2015. All patients ...

journal_title：Gynecologic oncology

authors： Tharavichitkul E,Chakrabandhu S,Klunklin P,Onchan W,Jia-Mahasap B,Wanwilairat S,Tippanya D,Jayasvasti R,Sripan P,Galalae RM,Chitapanarux I

更新日期：2018-03-01 00:00:00

abstract：:Abnormal nuclear DNA content, as determined by flow cytometry, when combined with conventional prognostic variables such as tumor grade or stage at diagnosis, appears to identify patients who are at increased risk for recurrence of disease. The DNA content of ovarian dysgerminoma, a tumor that is homologous to testicu...

journal_title：Gynecologic oncology

authors： Palmquist MB,Webb MJ,Lieber MM,Gaffey TA,Nativ O

更新日期：1992-01-01 00:00:00

abstract：OBJECTIVES:We have previously shown that high activity of lactate dehydrogenase (LD) isoenzymes 4 and 5 in terine aspirates is a marker for endometrial carcinoma. The purpose of this study was to identify an abnormal activity profile of LD2-5 using LD1 as an internal standard, thereby being able to dispense with measur...

journal_title：Gynecologic oncology

authors： Niklasson O,Skude G,Marsal K,Casslén B

更新日期：2004-05-01 00:00:00

abstract：OBJECTIVE:The objective was to determine the frequency with which regression or progression of disease without treatment occurred in women diagnosed with squamous cell cervical carcinoma in situ (CIS) during pregnancy. METHODS:. A retrospective chart review of all women evaluated at the University of Iowa Colposcopy C...

journal_title：Gynecologic oncology

authors： Coppola A,Sorosky J,Casper R,Anderson B,Buller RE

更新日期：1997-11-01 00:00:00

abstract：BACKGROUND:Human papillomavirus type 16 variants have been described and may have different biologic activities: this has implications for the design of HPV vaccines. OBJECTIVES:The aim of this study was to see if the HPV16 variant E-G 131 can be detected in women with preinvasive disease and to consider the histologi...

journal_title：Gynecologic oncology

authors： Etherington IJ,Ellis JR,Luesley DM,Moffitt DD,Young LS

更新日期：1999-01-01 00:00:00

abstract：OBJECTIVE:Lymph node status in endometrial cancer is a major prognostic factor. Sentinel lymph node (SLN) biopsy using radiocolloid and blue dye labeling has emerged as an alternative to systematic lymphadenectomy. This technique requires a preoperative lymphoscintigraphy. The aim of this study was to evaluate the limi...

journal_title：Gynecologic oncology

authors： Ballester M,Rouzier R,Coutant C,Kerrou K,Daraï E

更新日期：2009-02-01 00:00:00

abstract：:The COVID-19 pandemic has challenged our ability to provide timely surgical care for our patients. In response, the U.S. Surgeon General, the American College of Srugeons, and other surgical professional societies recommended postponing elective surgical procedures and proceeding cautiously with cancer procedures that...

journal_title：Gynecologic oncology

authors： Fader AN,Huh WK,Kesterson J,Pothuri B,Wethington S,Wright JD,Bakkum-Gamez JN,Soliman PT,Sinno AK,Leitao M,Martino MA,Karam A,Rossi E,Brown J,Blank S,Burke W,Goff B,Yamada SD,Uppal S,Dowdy SC

更新日期：2020-08-01 00:00:00

abstract：:HIV infection among women is increasing in the United States. Since January 1993, cervical cancer has been considered an AIDS-defining illness. We report a rare case of squamous cell carcinoma arising in a teratoma of the uterine cervix in an HIV-infected patient. This patient was treated with a radical hysterectomy, ...

journal_title：Gynecologic oncology

authors： Bell MC,Schmidt-Grimminger DC,Connor MG,Alvarez RD

更新日期：1996-03-01 00:00:00

abstract：OBJECTIVES:The precise role of gonadotropins in the carcinogenesis of epithelial ovarian cancer remains uncertain. Recently, the haplotype of two single nucleotide polymorphisms, Thr307Ala (rs6165) and Asn680Ser (rs6166), has been described as a risk factor for ovarian cancer in Chinese women. In this study we investig...

journal_title：Gynecologic oncology

authors： Heubner M,Riemann K,Otterbach F,Kimmig R,Kasimir-Bauer S,Siffert W,Wimberger P

更新日期：2009-03-01 00:00:00

abstract：:The radical hysterectomy is often associated with severe bladder dysfunction and colorectal motility disorders. These issues may arise as a result of damage incurred to the motor and sensory autonomic nerve supply, both of sympathetic and parasympathetic origin, that innervate the uterus, vagina, urinary bladder, and ...

journal_title：Gynecologic oncology

authors： Fujii S

更新日期：2008-11-01 00:00:00

abstract：OBJECTIVE:Endometrial cancer mortality disproportionately affects black women and whether greater prevalence of obesity plays a role in this disparity is unknown. We examine the effect of race on post-surgical complications, length of stay, and mortality specifically in a morbidly obese population. METHODS:Black and w...

journal_title：Gynecologic oncology

authors： Cote ML,Ruterbusch JJ,Ahmed Q,Bandyopadhyay S,Alosh B,Abdulfatah E,Seward S,Morris R,Ali-Fehmi R

更新日期：2014-04-01 00:00:00

abstract：:We performed a study to evaluate the relationships between the surgical stage (FIGO, 1989), histological tumor grade, myometrial invasion, peritoneal cytology, lymph node metastasis and prognosis, and DNA ploidy determined by flow cytometry in paraffin-embedded blocks of resected cancer lesions from 76 patients with u...

journal_title：Gynecologic oncology

authors： Ikeda M,Watanabe Y,Nanjoh T,Noda K

更新日期：1993-07-01 00:00:00

abstract：OBJECTIVE:The aim of our study was to retrospectively examine the proliferating cell nuclear antigen (PCNA) immunoreactivity of tumor cells in curettage specimens containing endometrioid adenocarcinoma and obtained immediately before definitive surgical staging. This PCNA index was compared with the one subsequently de...

journal_title：Gynecologic oncology

authors： Garzetti GG,Ciavattini A,Goteri G,De Nictolis M,Romanini C

更新日期：1996-04-01 00:00:00

abstract：:The purpose of this study was to determine the influence of tumor grade, distribution, and extent of carcinomatosis in minimal residual epithelial ovarian cancer after primary optimal cytoreductive surgery. Between 1978 and 1990, 112 patients with stage III epithelial ovarian cancer underwent primary cytoreductive sur...

journal_title：Gynecologic oncology

authors： Farias-Eisner R,Teng F,Oliveira M,Leuchter R,Karlan B,Lagasse LD,Berek JS

更新日期：1994-10-01 00:00:00

abstract：BACKGROUND:The combination ascites, pleural effusion, and elevated CA 125 are usually associated with a malignancy. CASE:A 38-year-old SLE patient consulted her physician for shortness of breath. On clinical examination, she had a tender abdomen and reduced breathing sounds. X-ray and computed tomography of the chest ...

journal_title：Gynecologic oncology

authors： Tjalma WA

更新日期：2005-04-01 00:00:00

abstract：OBJECTIVE:Delay in diagnosis of endometrial cancer may be associated with disease progression and impact management and outcomes. Social and cultural barriers influence recognition of symptoms and self-advocacy in seeking care. Associations between social determinants of health (SDH) and disease presentation have been ...

journal_title：Gynecologic oncology

authors： Helpman L,Pond GR,Elit L,Anderson LN,Seow H

更新日期：2020-07-01 00:00:00