Myocardial positron tomography with manganese-52m.

Abstract:

:The biodistribution of radiomanganese (54Mn) was studied in mice, rats, and dogs. Disappearance of radioactivity from the blood was extremely rapid, with a half-time of approximately 0.8 minutes. This resulted in very favorable myocardium-to-blood ratios, even at early times after administration. The myocardial uptake in dogs was greater than 3% at three and 15 minutes, with myocardium-to-blood ratios of about 40:1 at 15 minutes. Positron tomograms obtained with 52mMn clearly demonstrated regional myocardial perfusion. There was good correlation (r = 0.89) of microsphere-to-radiomanganese distribution in the infarcted dog heart.

journal_name

Radiology

journal_title

Radiology

authors

Atkins HL,Som P,Fairchild RG,Hui J,Schachner E,Goldman A,Ku T

doi

10.1148/133.3.769

subject

Has Abstract

pub_date

1979-12-01 00:00:00

pages

769-74

issue

3 Pt 1

eissn

0033-8419

issn

1527-1315

journal_volume

133

pub_type

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