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Negative symptom configuration in first episode Schizophrenia: findings from the "Parma Early Psychosis" program.

Abstract：

:Purpose: Identifying distinct dimensions of negative symptoms in First Episode Schizophrenia (FES) might result in a better understanding and treatment of this invalidating symptomatology. Aim of this study was to examine negative symptom structure in FES patients using the Positive and Negative Syndrome Scale (PANSS).Materials and Methods: All 147 participants, aged 12-35 years, completed the PANSS and the Global Assessment of Functioning (GAF) scale. A principal component analysis with varimax rotation was performed to investigate PANSS negative symptom structure in the FES total sample.Results: A 2-factor model (i.e. "Expressive Deficits" and "Asociality" dimensions) was identified. Only "Expressive Deficits" domain had a significant negative correlation with baseline GAF score.Conclusions: This bipartite solution seems to be adequate to describe the phenomenological variety of negative symptoms experienced by FES individuals at the point of entry in early intervention services.

journal_name

Nord J Psychiatry

journal_title

Nordic journal of psychiatry

authors

Pelizza L,Landi G,Pellegrini C,Quattrone E,Azzali S,Pellegrini P,Leuci E

doi

10.1080/08039488.2019.1695286

subject

Has Abstract

pub_date

2020-05-01 00:00:00

pages

251-258

issue

4

eissn

0803-9488

issn

1502-4725

journal_volume

74

pub_type

杂志文章

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