Abstract:
:Metabolic side-effects of atypical antipsychotics have led to concern about their relative safety compared with low doses of conventional neuroleptics. Akathisia is an often misdiagnosed side-effect, which leads to non-compliance and sometimes even exacerbation of psychosis or suicidal behaviour. In fact, little is known about the differences between antipsychotic drugs in clinical practice, since only as few as 20% of patients may be eligible for studies comparing antipsychotic medications with each other. The aim of this study was to find out if the use of conventional antipsychotics is associated with an increased risk of akathisia (compared with atypical antipsychotics) even when low doses of conventional antipsychotics are used. The Barnes Akathisia Rating Scale was used to evaluate akathisia in 100 outpatients on antipsychotic medication. Conventional antipsychotics were associated with an increased risk of akathisia compared with atypical antipsychotics, although the chlorpromazine equivalent doses of conventional antipsychotics were lower than those of the atypicals. An additional akathisia-provoking effect of SSRIs could not be ruled out. The results suggest favouring atypical antipsychotic medication in patients who may easily develop akathisia.
journal_name
Nord J Psychiatryjournal_title
Nordic journal of psychiatryauthors
Markkula J,Helenius H,Lauerma Hdoi
10.1080/08039480701226146subject
Has Abstractpub_date
2007-01-01 00:00:00pages
152-7issue
2eissn
0803-9488issn
1502-4725pii
777075951journal_volume
61pub_type
杂志文章abstract::Finland was the first European country to give a high priority to the development of specialized psychiatric services for adolescents. The aim of this paper is to 1) describe the development of these services, 2) study the status and the functioning of psychiatric services for adolescents in 2000 and 3) present some f...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039480310000248
更新日期:2003-01-01 00:00:00
abstract::The connection between self-image and depressive symptoms in non-clinical adolescent populations has not been well documented in large samples of teenagers. Our purpose was to investigate the correlation between self-image and depressive symptoms. To assess the adolescent's self-concept, we used the Offer Self-Image Q...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039480310003461
更新日期:2003-01-01 00:00:00
abstract::Background: As a result of deinstitutionalization of psychiatric treatment and care, many people with severe mental illness have been offered supported accommodation. However, research on this costly intervention in Norway has been scarce. Aims: The aim of this study was to prospectively investigate the clinical and d...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2019.1606938
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Unusual reactions to sensory stimuli are experienced by 90-95% of people with an autism spectrum condition (ASC). Self-reported sensory reactivity in ASC has mainly been measured with generic questionnaires developed and validated on data from the general population. Interest in sensory reactivity in ASC inc...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2015.1053984
更新日期:2016-01-01 00:00:00
abstract:BACKGROUND:The ward atmosphere of psychiatric care units has a major impact on treatment and satisfaction for both patients and staff. The Ward Atmosphere Scale (WAS) was developed to capture the ward atmosphere in different psychiatric settings and is a well-established instrument for this purpose. However, there is n...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039480903524913
更新日期:2010-10-01 00:00:00
abstract:BACKGROUND:In 2003, the German psychiatrist Michael Linden proposed the new mental disorder concept of "post-traumatic embitterment disorder (PTED)". PTED is defined as the mental reaction to a critical event that is normal, but not everyday, such as conflict at work. The patient sees this event as unjust and as a viol...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039480903398185
更新日期:2010-05-04 00:00:00
abstract:BACKGROUND:Stalking is a considerable health problem. In order to develop interventions for victims, more knowledge is needed concerning prevalence, stress and coping related to stalking as well as associated symptomatology in the victims. This is the first population-based study of stalking in Norway. AIMS:To examine...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2013.844273
更新日期:2014-07-01 00:00:00
abstract::Some of the most frequently reported mental health problems in traumatized refugees are depression, anxiety and post-traumatic stress disorder (PTSD). The aim of this paper is to describe a group of tortured refugees referred to the Rehabilitation and Research Centre for Torture Victims (RCT) and to study the importan...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039480500504982
更新日期:2006-01-01 00:00:00
abstract::Objective: Misophonia is a neurophysiological disorder, phenotypically characterized by heightened autonomic nervous system arousal which is accompanied by a high magnitude of emotional reactivity to repetitive and pattern-based auditory stimuli. This study identifies the prevalence of psychiatric symptoms in misophon...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2019.1609086
更新日期:2019-01-01 00:00:00
abstract:BACKGROUND:Impulsivity is closely related to substance use and abuse, both as a contributor to use and as a consequence of use. Particular dimensions of temperament and character were reported to be associated with trait impulsivity in different populations. AIM:The aim of the present study was to evaluate the relatio...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2013.830772
更新日期:2014-07-01 00:00:00
abstract::The aim of the study was to compare the screening properties of two General Health Questionnaire (GHQ) versions and the Symptom Checklist (SCL-90), and to evaluate them as psychiatric screening instruments in Finland. We administered the GHQ-36 and the SCL-90 to psychiatric outpatients (n=207) and to a community sampl...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039480310001418
更新日期:2003-01-01 00:00:00
abstract::We investigated the association between cognitive performance and major depressive disorder (MDD) in adolescents seeking outpatient treatment. We used several tests comparing cognitive capacities between 16 adolescents with MDD and 25 adolescents not diagnosed as suffering from psychiatric illness according to the Str...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/080394802317607165
更新日期:2002-01-01 00:00:00
abstract:BACKGROUND:Although cognitive behavioural therapy (CBT) has been shown to be an efficacious treatment for social phobia (SP), many patients drop out or achieve little or no benefit from treatment. This fact is generally considered an argument for the importance of studies of predictor variables. AIMS:This paper system...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,评审
doi:10.3109/08039480903426929
更新日期:2010-04-01 00:00:00
abstract::Aims: The current study explore the relationship between the trajectories of primary panic disorder symptoms and secondary depressive symptoms during guided internet-delivered cognitive behaviour therapy for panic disorder. Materials and methods: The patients (N=143) were recruited from an ongoing effectiveness study ...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2019.1646803
更新日期:2019-10-01 00:00:00
abstract::Studies conducted outside of Scandinavia indicate that most adolescents with substance misuse problems suffer from co-morbid mental disorders. The present study assessed the mental health of adolescents seeking help for substance misuse problems in a large Swedish city. Parents' mental health was also examined. The sa...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039480701643423
更新日期:2007-01-01 00:00:00
abstract:OBJECTIVE:To analyse the dosage pattern of antipsychotic drugs for schizophrenia in ambulatory care in Sweden. METHOD:The study was based on a nationwide consecutive weekly random sample of physicians during the period 1991-98 comprising 265,331 visits. RESULTS:In 515 visits (0.19%), antipsychotics were prescribed fo...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039480307280
更新日期:2003-01-01 00:00:00
abstract:BACKGROUND:Both obesity and smoking are common in schizophrenia patients taking clozapine, causing cardiovascular disease and premature deaths. METHODS:Two hundred and thirty-seven patients with schizophrenia or related psychoses treated with clozapine completed the Liverpool University Neuroleptic Assessment Scale (L...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2014.907340
更新日期:2014-11-01 00:00:00
abstract::The main objective of this study was to compare life skills between psychotic patients with substance abuse problems and psychotic patients without substance abuse problems. This is a cross-sectional study of 48 patients (26 inpatients and 22 outpatients) in a clinic for early intervention in psychosis. Patients were ...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039480600583811
更新日期:2006-01-01 00:00:00
abstract:PURPOSE:To evaluate the effect of Individual Enabling and Support (IES) on empowerment and depression severity as compared to Traditional Vocational Rehabilitation (TVR) in people with affective disorders at 12 months follow-up. Additionally, longitudinal changes within the intervention groups and the correlation over ...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,随机对照试验
doi:10.1080/08039488.2018.1432685
更新日期:2018-05-01 00:00:00
abstract:AIM:Toxoplasma gondii may play a role in the development of psychiatric diseases by affecting the brain. The purpose of this study was to examine the relation between serum toxoplasma IgG positivity and obsessive-compulsive disorder (OCD) and generalized anxiety disorder (GAD) in children and adolescents. METHOD:Sixty...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2017.1385850
更新日期:2018-01-01 00:00:00
abstract:BACKGROUND:Long acting injectable antipsychotics (LAI-APs) are considered a major advance in psychiatric treatment concerning treatment adherence and outcomes. Yet, both, doctors and patients remain sceptical. AIM:To explain the rationale for using LAI-APs, review their effectiveness and explore barriers to use. METH...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,评审
doi:10.1080/08039488.2018.1525638
更新日期:2018-09-01 00:00:00
abstract:BACKGROUND:Although the effect of obsessive-compulsive disorder (OCD) on sleep is not well-known, recent studies suggest an association between OCD and sleep quality. AIMS:We aimed to assess sleep quality in children and adolescents with OCD and to seek its association with OCD symptoms and OCD severity. METHODS:All ...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2020.1785005
更新日期:2021-01-01 00:00:00
abstract:BACKGROUND:Recently, it was reported that antipsychotic treatment reverted Contactin Associated Protein-Like 3 (CASPR3, same as CNTNAP3) mRNA expressions in leukocytes of schizophrenia (SCZ) subjects to the same levels as healthy controls. CASPR3 was expressed in various regions of the mice brain (cortex, frontal lobes...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2017.1291720
更新日期:2017-05-01 00:00:00
abstract::The objective of this study was to account for acute stress disorder (ASD) and post-traumatic stress disorder (PTSD) morbidity in a self-report survey of traffic accident victims and to evaluate the relationship between ASD and PTSD in this sample, and furthermore, to find both a model of independent variables account...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,多中心研究
doi:10.1080/08039480410006304
更新日期:2004-01-01 00:00:00
abstract::This paper reviews the main principles of Interpersonal Psychotherapy and its adaptation for depressed adolescents (IPT-A). The work of IPT-A is put in the context of the significant problem of depression in adolescence and the other treatments and their efficacy in the treatment of adolescent depression. The paper al...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,评审
doi:10.1080/08039480601022397
更新日期:2006-01-01 00:00:00
abstract::Post-traumatic stress disorder (PTSD) has been included in the DSM category of psychiatric diagnoses since 1980, classified as an anxiety disorder. Since that time, its definition has undergone considerable change and today many physicians are not aware of its current diagnostic criteria or the clinical significance o...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章,评审
doi:10.1080/08039480410005927
更新日期:2004-01-01 00:00:00
abstract:BACKGROUND:One of the major challenges for research in the field of human aggression is the need to define the role of personality and trait-like dimensions, such as impulsivity and aggressiveness, in predisposing to violent behavior. AIMS:1) To determine whether trait- aggressiveness and impulsivity may be associated...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2012.756061
更新日期:2014-01-01 00:00:00
abstract::Background Immunological mechanisms may be responsible for the development and maintenance of schizophrenia symptoms. Aim The aim of this study is to measure tumour necrosis factor-alpha (TNF-α), soluble tumour necrosis factor-alpha receptor I (sTNF-αRI), and soluble tumour necrosis factor-alpha receptor II (sTNF-αRII...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2015.1122079
更新日期:2016-07-01 00:00:00
abstract:BACKGROUND:The Rorschach Inkblot Method is regarded as an important clinical instrument for detailed diagnostic description of the integrative capacities of individuals in psychotic states and as an instrument for measuring progression in the course of treatment. AIMS:To describe relevant Rorschach variables at baseli...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.3109/08039488.2011.595500
更新日期:2012-04-01 00:00:00
abstract:BACKGROUND:Extreme self-harming behavior is a major challenge for patients and health services. Nevertheless, this patient population is poorly described in research literature. AIMS:The aim of this study was to assess the volume of patients with extensive psychiatric hospitalization due to extreme self-harming behavi...
journal_title:Nordic journal of psychiatry
pub_type: 杂志文章
doi:10.1080/08039488.2018.1511751
更新日期:2018-11-01 00:00:00