Tissue characterization with T1, T2, and proton density values: results in 160 patients with brain tumors.

Abstract:

:A method by which the tissue parameters - T1, T2, and proton density - can be measured simultaneously was used in 160 patients with brain tumors to test the complete potential of magnetic resonance (MR) imaging for quantitative tissue characterization. MR tissue parameters of a wide variety of tumors, edema, white matter, and gray matter were determined. While normal brain tissues showed only small interindividual variations of tissue parameters, pathologic entities (tumor, edema) were characterized by wide ranges of T1, T2, and proton density values. The considerable overlapping of tissue parameters in different tumor entities, which were analyzed in a three-dimensional T1/T2/proton density space, indicates that a reliable diagnosis cannot be made on the basis of a quantitative evaluation of T1, T2, and proton density alone.

journal_name

Radiology

journal_title

Radiology

authors

Just M,Thelen M

doi

10.1148/radiology.169.3.3187000

subject

Has Abstract

pub_date

1988-12-01 00:00:00

pages

779-85

issue

3

eissn

0033-8419

issn

1527-1315

journal_volume

169

pub_type

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