Hepatocellular carcinoma: MR imaging findings in cirrhotic livers and noncirrhotic livers.

Abstract:

PURPOSE:To compare the magnetic resonance (MR) imaging findings of primary hepatocellular carcinoma (HCC) in cirrhotic versus noncirrhotic livers. MATERIALS AND METHODS:MR images in 36 patients with HCC (30 men and she women aged 42-84 years [mean age, 65 years]) were retrospectively reviewed. The number and size of hepatic lesions were assessed. Lesion margins were categorized as well circumscribed or ill defined. The presence of a capsule, intratumoral high signal intensity on T1-weighted MR images, and a stellate scar were determined. RESULTS:Eleven (31%) patients had MR imaging evidence of cirrhosis, and 25 (69%) did not: Lesions in cirrhotic livers differed significantly from those in noncirrhotic livers in terms of size (22 cm2 vs 99 cm2, P < .05), frequency of a solitary lesion (27% vs 72%, P < .05), and frequency of a central scar (6% vs 50%, P < .05). There was no difference between the cirrhotic and noncirrhotic livers with regard to tumor margin, intratumoral high signal intensity on T1-weighted images, or tumor capsule. CONCLUSION:Differences exist in the MR imaging appearance of HCC between patients with and those without cirrhosis, although there is overlap of imaging findings.

journal_name

Radiology

journal_title

Radiology

authors

Winston CB,Schwartz LH,Fong Y,Blumgart LH,Panicek DM

doi

10.1148/radiology.210.1.r99ja1975

subject

Has Abstract

pub_date

1999-01-01 00:00:00

pages

75-9

issue

1

eissn

0033-8419

issn

1527-1315

journal_volume

210

pub_type

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