The evolution of the basic concepts underlying the practice of radiotherapy from 1949 to 1977.

Abstract:

:In his overview of the history and theoretical developments of radiotherapy, the author stresses the following concepts: (a) sensitivity is not linked to histology but to the volume of cancer; (b) the dose must not necessarily be homogeneous in the target volume but related to varying volumes of cancer; (c) the fact that irradiation may not be the sole treatment in some tumors does not mean that it does not have a place in their management; (d) as a general rule, large tumors should not be treated with irradiation only, if gross cancer can be resected simply; (e) since there is a dose-response curve for control rates and for complications, an optimum dose level must be maintained; and (f) the patient's quality of life is a major concern.

journal_name

Radiology

journal_title

Radiology

authors

Fletcher GH

doi

10.1148/127.1.3

subject

Has Abstract

pub_date

1978-04-01 00:00:00

pages

3-19

issue

1

eissn

0033-8419

issn

1527-1315

journal_volume

127

pub_type

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