Abstract：
:This paper uses a neural network model to study the protective effect of dexmedetomidine on the anesthesia recovery period and neurocognitive function in elderly patients undergoing radical resection of colorectal cancer. Eighty-eight patients with colorectal cancer who underwent radical surgery in our hospital from January 2015 to June 2017 were randomly divided into groups: study (43 cases) and control (45 cases). The study group was treated with dexmedetomidine for anesthesia. Patients in the study group were given a slow pumping dose of 1 μg/kg to prepare dexmedetomidine at a dose of 1 μg/kg. The pumping time was >10 minutes, and the dose was 0.3 μg after completion. The loading dose of 0.3 (kg·h) was maintained intraoperatively; the control group was given the same amount of saline infusion by the same infusion method. The study found that the probability of cognitive dysfunction in the study group was significantly lower than that in the control group, and the degree of cognitive dysfunction in the study group was significantly lower than that in the control group (P < 0.05). Therefore in the operation of elderly patients with colorectal cancer radical surgery, dexmedetomidine is used for anesthesia to protect postoperative cognitive function and reduce the incidence of cognitive dysfunction. Extensive promotion and application in the clinic.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Chen H,Li Fdoi
10.1016/j.wneu.2020.01.012subject
Has Abstractpub_date
2020-06-01 00:00:00pages
688-695eissn
1878-8750issn
1878-8769pii
S1878-8750(20)30019-Xjournal_volume
138pub_type
杂志文章,随机对照试验abstract：OBJECTIVE:The objective of this study was to evaluate the association between asymptomatic unruptured intracranial aneurysms (IAs) and pituitary adenomas (PAs) in Chinese people. METHODS:In total, 434 patients with newly diagnosed PA and 252 control subjects from the general population who underwent brain computed tom...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.084
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Traumatic cervical pseudomeningoceles (TCPs) occur secondary to traction of the cervical nerve roots resulting in violation of the dura. Surgical repair is not necessary in most cases because pseudomeningoceles have a high propensity to spontaneously resolve with conservative management alone. Currently, the...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.04.017
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Low-grade gliomas (LGGs) are known to progress to glioblastoma (GBM), decreasing the chances of survival. The tumor necrosis factor receptor CD40 and its ligand CD40L have shown value as biomarkers for GBM. The present study evaluated the role of CD40/CD40L in LGG and GBM in differentiating isocitrate dehydr...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.05.112
更新日期：2019-10-01 00:00:00
abstract：BACKGROUND:The current literature regarding cranial giant cell tumor (GCT) management includes scattered case reports and small case series. We present a comprehensive literature review and meta-analysis on this subject, along with a case report describing our management of a patient with temporal GCT. METHODS:A syste...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.wneu.2016.05.086
更新日期：2016-12-01 00:00:00
abstract：OBJECTIVE:Venous thromboembolism (VTE) is an important complication after spine surgery with an incidence of 31%. To our knowledge, no study has reported a time-dependent examination of factors influencing VTE. We report factors influencing first and multiple VTE events and perform a time-dependent analysis. METHODS:A...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.03.068
更新日期：2015-09-01 00:00:00
abstract：BACKGROUND:An aneurysm embedded in a pituitary adenoma is rare, and treatment for both the aneurysm and pituitary adenoma is complex and controversial. CASE DESCRIPTION:A 53-year-old woman presented with a visual field defect. Magnetic resonance imaging showed a pituitary adenoma and coexistence of an aneurysm located...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2019.10.159
更新日期：2020-02-01 00:00:00
abstract：:We present an uncommon case of holocord, "rosary bead-like," multiloculated syringomyelia consistent with a fourth ventricle outlet obstruction in a 2-month-old infant who was previously shunted for posthemorrhagic hydrocephalus of prematurity. The shunt malfunction resulted in a syringomyelia because of the simultane...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.04.158
更新日期：2020-07-01 00:00:00
abstract：BACKGROUND:Carcinoid tumors are neuroendocrine neoplasms derived from enterochromaffin cells. Central nervous system involvement is rare. The reported cases include metastases to brain or spinal cord, and primary skeletal or extradural disease resulting in compressive myeloradiculopathy. There are 2 previously reported...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.06.179
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:Cerebral venous complications related to neurosurgical interventions are only rarely reported in the literature. Internal cerebral veins (ICVs) are vulnerable to injury during neurosurgical approaches to the pineal and thalamic regions. The occurrence of unilateral postoperative ICV thrombosis in children is...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.03.008
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:X-linked hypophosphatemia (XLH) is the most common inherited form of renal phosphate wasting and inherited rickets. Patients have hyperplasia of fibrochondrocytes in tendons and ligaments, causing the structures to thicken and calcify. Thickening of the lamina, hypertrophy of facet joints, and calcification ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.07.076
更新日期：2016-10-01 00:00:00
abstract：BACKGROUND:The decision between conservative management and invasive treatment of juxtaorbital intracranial vascular anomalies can be challenging. Whereas arteriovenous malformations (AVMs) can lead to vision loss and are potentially life-threatening if they rupture, invasive endovascular and surgical procedures also c...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2013.01.093
更新日期：2014-07-01 00:00:00
abstract：OBJECTIVES:To investigate the extent of spinal cord compression and cerebrospinal fluid (CSF) space after T9 paddle lead spinal cord stimulation (SCS) using three-dimensional myelographic computed tomography scans. METHODS:Preoperative and postoperative three-dimensional myelographic computed tomography scans were per...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.186
更新日期：2018-10-01 00:00:00
abstract：BACKGROUND:Intraneural ganglia are benign mucinous cystic formations that originate within the epineurium of peripheral nerves. Different treatments have been recommended, with an overall satisfactory outcome. In this paper, we aim to evaluate the long-term outcomes of surgical treatment of peroneal intraneural ganglia...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.08.195
更新日期：2019-12-01 00:00:00
abstract：INTRODUCTION:Several methods have been proposed to achieve a watertight dural closure, including the use of fibrin sealant to reinforce sutures. We propose a fast technique using oxidized cellulose and fibrin glue to achieve firm and watertight closure of minor dural defects in supratentorial cranial surgery. TECHNICA...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2010.09.029
更新日期：2011-07-01 00:00:00
abstract：BACKGROUND:An awake throughout (AT) approach for awake craniotomy is mostly under utilized. The purpose of this study was to review the efficacy of the technique at our tertiary care center. The primary objective was to identify the incidence of perioperative complications. The secondary objective was to review the pat...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.127
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:In vascular reconstructive surgery, intraoperative confirmation of patency is performed by angiography, Doppler, or indocyanine videoangiography, but it is sometimes insufficient. OBJECTIVE:Using the FLOW 800 system (Carl Zeiss, Oberkochen, Germany), we confirmed patency in a quantitative relative evaluatio...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.11.072
更新日期：2018-02-01 00:00:00
abstract：BACKGROUND:Use of distal nerve transfer for improving upper limb function has been well described for patients with tetraplegic spinal cord injury and brachial plexus injuries but has not previously been described for Brown-Séquard type spinal cord injury. We describe our experience with 2 cases of combined Brown-Séqua...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.10.169
更新日期：2018-02-01 00:00:00
abstract：OBJECTIVE:Postcraniotomy infections have generally been treated by debridement of infected tissues, disposal of the bone flap, and delayed cranioplasty several months later to repair the resulting skull defect. Debridement followed by retention of the bone flap has also been advocated. Here we propose an alternative op...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2011.02.013
更新日期：2013-01-01 00:00:00
abstract：BACKGROUND:A standard post-concomitant radiochemotherapy involving adjuvant temozolomide (TMZ) was stopped after 6 cycles for high-grade gliomas (HGG). Several studies demonstrated that prolonged TMZ treatment increased survival for these patients. METHODS:This retrospective study aimed to compare changes in tumor vol...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.03.078
更新日期：2018-06-01 00:00:00
abstract：OBJECTIVE:To explore influence of reduction of slippage on radiologic parameters, clinical outcomes, and perioperative complications in treatment of grade II/III lumbar isthmic spondylolisthesis. METHODS:We divided 156 patients with grade II/III spondylolisthesis into 2 groups with preoperative balanced or unbalanced ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.08.217
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:The long-term durability of different modalities of intracranial aneurysm repair remains unclear. The aim of this study was to conduct a meta-analysis comparing long-term rates of intracranial aneurysm recurrence, retreatment, and rebleeding after surgical clipping or endovascular treatment (EVT). METHODS:A ...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.wneu.2019.08.002
更新日期：2019-12-01 00:00:00
abstract：BACKGROUND:Medical publications reflect the development of training, research, and health services. No objective data are available regarding neurosurgical publications from Morocco. Bibliometrics were used to evaluate the contribution of Moroccan neurosurgeons (MONSs) in neurosurgical journals worldwide and to discuss...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.02.122
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:Morphometric analysis or examination of symptoms in patients with Chiari malformation type I (CM-I) with various associations does not suffice for evaluation of surgical outcome of these patients. We assessed the relationship of morphologic changes in brain and spinal cord and disease symptoms with changes i...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.05.108
更新日期：2018-08-01 00:00:00
abstract：BACKGROUND:Cranial artery dolichoectasia is characterized by dilated, elongated, and tortuous cranial arteries. Dolichoectasia and dolichoectatic aneurysm-particularly of the internal carotid arteries (ICAs)-are rare but can lead to stroke. We report a case of suspected recurrent acute cerebral infarction and dolichoec...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.02.153
更新日期：2019-06-01 00:00:00
abstract：BACKGROUND:The foramen of Luschka is a natural aperture between the fourth ventricle and the subarachnoid space at the cerebellopontine angle. Membranous closure of this foramen is referred to as primary obstruction. Available information about this variant and its role in the development of the cysts of the posterior ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.01.037
更新日期：2018-04-01 00:00:00
abstract：OBJECTIVE:Nearly 9.2% of vestibular schwannomas (VS) recur. We evaluate the association of cell proliferative markers like MIB with recurrence in VS. METHODS:Retrospective data of 144 consecutive patients who underwent surgical excision for sporadic VS between January 2010 and July 2015 were collected. Comparison betw...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.09.039
更新日期：2018-12-01 00:00:00
abstract：OBJECTIVE:To report a series of four patients with uterine sarcoma, including one with müllerian adenosarcoma (MA) and three with low-grade endometrial stromal sarcoma (LGESS), who developed intracranial meningiomas while receiving the progesterone agonist megestrol acetate. METHODS:The hospital records, imaging studi...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2011.03.035
更新日期：2011-11-01 00:00:00
abstract：BACKGROUND:An increasing body of literature describing use of high-fidelity surgical training models is challenging long-held dogma that cadavers provide the best medium for postgraduate surgical skills training. The purpose of this study was to describe a surgical skills course comprising entirely synthetic training m...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.230
更新日期：2019-07-01 00:00:00
abstract：OBJECTIVES:To assess the outcomes in aggressively treated patients with aneurysmal intracerebral hematoma (ICH) and signs of brain herniation, and to investigate possible predictive factors. METHODS:This retrospective study included 43 patients with aneurysmal ICH who presented to the Emergency Department with brain h...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.03.011
更新日期：2018-06-01 00:00:00
abstract：BACKGROUND:Visual loss can be encountered in the immediate, early, or even delayed postoperative period after resection of skull base meningiomas involving the optic apparatus. Various mechanisms for visual loss can include mechanical injury, vascular insult, optic nerve and chiasm edema, and vasospasm of the blood sup...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.06.052
更新日期：2016-08-01 00:00:00
