Abstract：
OBJECTIVES:To investigate the extent of spinal cord compression and cerebrospinal fluid (CSF) space after T9 paddle lead spinal cord stimulation (SCS) using three-dimensional myelographic computed tomography scans. METHODS:Preoperative and postoperative three-dimensional myelographic computed tomography scans were performed in 15 patients with paddle lead SCS at T9 for neuropathic back and leg pain. Four axial levels between each row of the electrodes were selected and the cross-sectional areas of thecal sac and spinal cord, the width of anterior and posterior CSF space, and contact angle of the lead within T9 spinal canal were measured with 12-month pain relief assessment. RESULTS:The cross-sectional areas of thecal sac and spinal cord under each contact of paddle leads decreased significantly (23.89 ± 11.48% and 9.45 ± 4.80%; P < 0.05, respectively). The width of posterior CSF space decreased by 38.65 ± 20.97% and that of anterior CSF space showed a greater reduction by 59.09 ± 18.39% (P < 0.05). We achieved a mean pain relief of 45.49 ± 13.73% at 12-month follow-up and found a significant correlation with percentage reduction in the area of the spinal cord. CONCLUSIONS:Significant reduction in the cross-sectional area of spinal cord and anterior CSF space as well as thecal sac and posterior CSF space resulted in deformation of the spinal cord under paddle leads at T9 within 7 postoperative days. Close approximation to the dorsal column and the mass effect of paddle leads may determine the clinical outcome of paddle lead SCS and also raise safety concerns.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Son BC,Ko HC,Choi JGdoi
10.1016/j.wneu.2018.06.186subject
Has Abstractpub_date
2018-10-01 00:00:00pages
e323-e334eissn
1878-8750issn
1878-8769pii
S1878-8750(18)31402-5journal_volume
118pub_type
杂志文章abstract：OBJECTIVE:To compare outcomes in the setting of spontaneous intracerebral hemorrhage (ICH) in patients taking aspirin (acetylsalicylic acid [ASA]) versus patients taking clopidogrel before hospitalization. METHODS:Patients admitted to the neurosurgical service with a spontaneous ICH while taking an antiplatelet agent ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2011.02.010
更新日期：2011-07-01 00:00:00
abstract：OBJECTIVES:To assess the outcomes in aggressively treated patients with aneurysmal intracerebral hematoma (ICH) and signs of brain herniation, and to investigate possible predictive factors. METHODS:This retrospective study included 43 patients with aneurysmal ICH who presented to the Emergency Department with brain h...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.03.011
更新日期：2018-06-01 00:00:00
abstract：:Abraham Lincoln was the 16(th) President of the United States of America. On April 14, 1865, shortly after his re-election and the conclusion of the Civil War, Lincoln was shot and killed by John Wilkes Booth. Although numerous physicians tended to the President shortly after his injury, he passed away the next mornin...
journal_title：World neurosurgery
pub_type： 传,历史文章,杂志文章,评审
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更新日期：2015-11-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.09.008
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pub_type： 杂志文章
doi：10.1016/j.wneu.2019.06.022
更新日期：2019-09-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-12-28 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.08.195
更新日期：2019-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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journal_title：World neurosurgery
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更新日期：2020-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.05.049
更新日期：2016-08-01 00:00:00
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pub_type： 杂志文章
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更新日期：2016-06-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2021-01-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.02.089
更新日期：2020-06-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2018-12-31 00:00:00
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pub_type： 杂志文章,meta分析
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更新日期：2018-12-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2019-01-01 00:00:00
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pub_type： 杂志文章
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pub_type： 杂志文章,meta分析,评审
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journal_title：World neurosurgery
pub_type： 杂志文章
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更新日期：2019-01-22 00:00:00
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pub_type： 杂志文章,评审
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更新日期：2020-07-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章,评审
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更新日期：2018-10-01 00:00:00
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更新日期：2017-01-01 00:00:00
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pub_type： 杂志文章
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更新日期：2018-08-01 00:00:00
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更新日期：2020-05-01 00:00:00
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journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.01.028
更新日期：2018-04-01 00:00:00
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journal_title：World neurosurgery
pub_type： 临床试验,杂志文章
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