Abstract：
OBJECTIVE:Nearly 9.2% of vestibular schwannomas (VS) recur. We evaluate the association of cell proliferative markers like MIB with recurrence in VS. METHODS:Retrospective data of 144 consecutive patients who underwent surgical excision for sporadic VS between January 2010 and July 2015 were collected. Comparison between groups based on recurrence of VS was done. RESULTS:The average age of the study population was 43.95 ± 12.86 years with 77 (53.5%) men. The average maximal diameter of VS was 40.25 ± 7.23 mm. Gross total resection was done in 52 (36.1%) patients. While near total resection was performed in 81 (56.3%) patients, the remaining 11 (7.6%) patients underwent a subtotal resection. The mean follow-up period was 37.99 ± 10.09 months (24-60). Recurrence of VS was observed in 18 (12.5%) patients. There was no difference between the groups for diameter of the tumor (42.22 ± 8.04 vs. 39.64 ± 7.00 mm; P = 0.191). The average MIB index value was higher in patients with recurrence of tumor at follow-up (4.78 ± 5.77 vs. 1.89 ± 1.48 mm; P < 0.001). There was no difference between the groups for extent of resection or postoperative complications. MIB was the only significant predictor for recurrence (β = 1.355 (1.07-1.78; confidence interval 95%); P = 0.031). On receiver operating characteristic curves, a cutoff value of 3.5% for MIB showed a specificity of 84.1%. CONCLUSIONS:MIB index ≥3.5% is associated with recurrence in VS. Maximal diameter of the tumor and extent of resection are perhaps not associated with recurrence of VS.
journal_name
World Neurosurgjournal_title
World neurosurgeryauthors
Panigrahi M,Kumar D,Vooturi S,Madigubba Sdoi
10.1016/j.wneu.2018.09.039subject
Has Abstractpub_date
2018-12-01 00:00:00pages
e1203-e1207eissn
1878-8750issn
1878-8769pii
S1878-8750(18)32085-0journal_volume
120pub_type
杂志文章abstract：BACKGROUND:Neurocysticercosis, a common parasitic infection in developing areas, usually exists in supratentorial parenchyma. Literature review shows few case reports published for cerebellopontine angle cysticercosis, but its coexistence with a schwannoma in the same cistern has never been seen before. This leads to c...
journal_title：World neurosurgery
pub_type：
doi：10.1016/j.wneu.2020.10.111
更新日期：2020-10-24 00:00:00
abstract：BACKGROUND:Spinal intradural tumors are usually removed with laminectomy/laminotomy with a midline dural incision. Pain, discomfort, postoperative kyphosis, and instability may be minimized with unilateral microsurgery. METHODS:Seventy patients with schwannoma (73 tumors) and 27 patients with meningioma (29 tumors) we...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.09.099
更新日期：2016-01-01 00:00:00
abstract：BACKGROUND:Given the genetic and proteomic advances of the past decade, understanding of the molecular etiopathogenesis of several complex diseases is increasing. Intervertebral disc disease (IVDD) is no different from other complex diseases where both environmental and genetic constituents are considered causes. This ...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.wneu.2011.07.014
更新日期：2012-03-01 00:00:00
abstract：INTRODUCTION:Neurocutaneous melanosis (NCM) is a rare congenital syndrome. Except for some retrospective studies, information on clinical follow-up and management of these patients are limited. This study aimed to review our experience on diagnostic protocol and clinical follow-up of patients with NCM in a referral chi...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.11.091
更新日期：2020-11-24 00:00:00
abstract：BACKGROUND:Accurate assessment of therapeutic response in patients with brain abscess (BA) is essential to direct appropriate therapy. This study was performed with an aim to see the treatment-induced changes in diffusion tensor imaging (DTI) indices (i.e., fractional anisotropy [FA] and mean diffusivity [MD]) in follo...
journal_title：World neurosurgery
pub_type： 临床试验,杂志文章
doi：10.1016/j.surneu.2009.04.003
更新日期：2010-01-01 00:00:00
abstract：OBJECTIVE:To determine infection rate (IR) and to identify modifiable risk factors (RF) in cranial neurosurgery in a neurosurgical department for tertiary referral as part of an infection control surveillance to reduce surgical site infections (SSI). METHODS:A prospective SSI incidence cohort study from February 2013 ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.12.062
更新日期：2018-03-01 00:00:00
abstract：BACKGROUND:The use of titanium alloy (Ti) rods is frequently associated with rod fracture after spinal fixation. To address this issue, cobalt chrome (CoCr) rods, which are advantageous because of their greater strength and resistance to fatigue relative to Ti rods, have been introduced. The purpose of the present stud...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.04.031
更新日期：2017-07-01 00:00:00
abstract：OBJECTIVE:Shot-within-shot (SWS) optimization is a new planning technique that relies on various combinations of shot weighting and prescription isodose line (IDL) to reduce beam-on time. The method differs from other planning techniques that incorporate mixed collimation, multiple stereotactic coordinates, and traditi...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.11.140
更新日期：2019-03-01 00:00:00
abstract：OBJECTIVE:To compare bony spur resection (BR) with bony spur nonresection (BN) treatment in patients with congenital scoliosis and type I split cord malformation. METHODS:Patients with congenital scoliosis and type I split cord malformation who underwent corrective surgery in a single institution from 2008 to 2015 wer...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.01.265
更新日期：2019-05-01 00:00:00
abstract：OBJECTIVE:We present a case of multiple myxoma-related intracranial aneurysms and reviewed the recent relevant literature to investigate their natural course and develop a reasonable treatment algorithm. METHODS:We have reported a new case of multiple myxoma-related intracranial aneurysms and performed a search of cur...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2019.09.014
更新日期：2020-01-01 00:00:00
abstract：BACKGROUND AND OBJECTIVE:Metastasis to the spinal column is a common feature of primary tumors of the breast, prostate, lung, and other organs. Surgical intervention can be performed via the traditional open surgery (OS) approach or the minimally invasive surgery (MIS) approach. This study aims to assess the available ...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析,评审
doi：10.1016/j.wneu.2018.01.176
更新日期：2018-04-01 00:00:00
abstract：BACKGROUND:Cerebral venous complications related to neurosurgical interventions are only rarely reported in the literature. Internal cerebral veins (ICVs) are vulnerable to injury during neurosurgical approaches to the pineal and thalamic regions. The occurrence of unilateral postoperative ICV thrombosis in children is...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2020.03.008
更新日期：2020-06-01 00:00:00
abstract：BACKGROUND:More than 120,000 anterior cervical discectomy and fusions (ACDFs) are performed annually. Pseudarthrosis is a potential delayed adverse event that affects up to 33% of patients. The degree to which this adverse event affects both patient quality-of-life (QOL) outcomes and health care costs is poorly underst...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.09.104
更新日期：2020-01-01 00:00:00
abstract：:Basilar bifurcation is a challenging site for aneurysm clipping. Anatomical factors such as size and projection of the aneurysm, distance between the aneurysm neck and the dorsum sellae, and location of the basilar bifurcation contribute to surgical complexity. Endovascular treatment has been used more frequently than...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.12.093
更新日期：2018-12-31 00:00:00
abstract：OBJECTIVE:To investigate the noninferiority of facet joint- and nuchal ligament-sparing laminectomy (FNL) compared with conventional open-door laminoplasty. METHODS:This retrospective study analyzed 31 patients who underwent FNL (7 women; median age, 71 years) and 29 patients who underwent laminoplasty (9 women; media...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.01.187
更新日期：2020-05-01 00:00:00
abstract：OBJECTIVE:The surgical approach for the trigeminal nerve involves veins connected to the superior petrosal and tentorial sinus, and we should pay special attention to these veins. We investigated intraoperative and postoperative bleeding using our database. METHODS:A prospectively accumulated database of 247 microvasc...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.139
更新日期：2018-10-01 00:00:00
abstract：OBJECTIVE:The relationship between urgent decompression and neurologic recovery for traumatic spinal cord injury (TSCI) remains controversial. This meta-analysis was conducted to determine the beneficial effects of surgery within 8 hours for patients with TSCI. METHODS:A systematic search in EMBASE, MEDLINE, Cochrane ...
journal_title：World neurosurgery
pub_type： 杂志文章,meta分析
doi：10.1016/j.wneu.2020.04.230
更新日期：2020-08-01 00:00:00
abstract：BACKGROUND:Microvascular decompression (MVD) is the most definitive surgical treatment for trigeminal neuralgia (TN). In the case in which an atherosclerotic vertebrobasilar artery (aVBA) offends the trigeminal nerve, the postoperative outcomes have been reported to be less satisfactory in terms of symptom recurrence a...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.03.289
更新日期：2019-08-01 00:00:00
abstract：OBJECTIVE:Intracranial arterial dissection (IAD) is a rare cerebrovascular disease that is likely underdiagnosed because of the inherent difficulty of visualizing the subtle radiographic signs of the pathologic small intracranial arteries. No widespread consensus exists on the treatment of IAD, and thus it is often man...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.09.153
更新日期：2019-01-01 00:00:00
abstract：OBJECTIVE:To report our experience of endoscopic disc removal by anterior approach for management of cervical myelopathy in 210 patients. METHODS:A retrospective study of 187 cases of single- and 23 cases of double-level disc disease was performed. Cases of myelopathy with or without unilateral or bilateral radiculopa...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.04.107
更新日期：2018-07-01 00:00:00
abstract：BACKGROUND:Only a few case reports and case series exist reporting on primary chondrosarcomas of the spine. The objective of this study was to gain a better understanding of this patient population and surgical techniques used for treatment. METHODS:A systematic literature search was performed in January 2018 querying...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2018.06.189
更新日期：2018-11-01 00:00:00
abstract：OBJECTIVE:To measure the incidence and severity of cement extravasation in adult patients undergoing prophylactic vertebroplasty as part of a spinal reconstruction procedure. METHODS:Consecutive adult patients treated with prophylactic vertebroplasty during a spinal reconstruction procedure were reviewed over a 46-mon...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2019.11.034
更新日期：2020-02-01 00:00:00
abstract：OBJECTIVE:In vitro fertilization (IVF) is increasingly used for the treatment of infertile couples worldwide. The association between IVF and cancer risk in offspring is conflicting. We present a case of atypical teratoid/rhabdoid tumor (AT/RT) in a girl conceived by IVF and present results of systematic review of lite...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2018.02.012
更新日期：2018-05-01 00:00:00
abstract：BACKGROUND:Seizure is the second-most common presentation in patients with arteriovenous malformations (AVMs) and superimposes a significant burden on pediatric patients. Postoperative seizure risk in unruptured AVMs is underreported in the pediatric AVM literature. We aimed to characterize and identify predictive fact...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.05.031
更新日期：2017-09-01 00:00:00
abstract：BACKGROUND:Intraventricular and subarachnoid forms represent the relatively complex, albeit uncommon, manifestations of central nervous system involvement by cysticercal cysts. Cysticercal encystation inside the Blake's pouch remnant of mega cisterna magna (MCM) remains an extremely rare clinical scenario that, to the ...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.04.067
更新日期：2017-06-01 00:00:00
abstract：BACKGROUND:Postoperative delayed intracerebral hemorrhage (DICH) secondary to ventriculoperitoneal (VP) shunt is a rare but severe event. The present study aimed to investigate the incidence and risk factors related to DICH after placement of the VP shunt. METHODS:The clinical data from 532 patients with VP shunt were...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2017.07.133
更新日期：2017-11-01 00:00:00
abstract：BACKGROUND:Surgical treatment of giant vestibular schwannomas (GVS) is challenging. The philosophy of incomplete tumor resection may balance the preservation of facial nerve function and long-term tumor control. OBJECTIVE:We aimed to evaluate the outcome of facial nerve function and tumor control in treating GVS via o...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2016.06.119
更新日期：2016-10-01 00:00:00
abstract：OBJECTIVE:Meningeal hemangiopericytoma (HPC) is a rare, aggressive central nervous system tumor that tends to invade locally and to metastasize, and has a high rate of recurrence. METHODS:This study presents a retrospective review of patients managed for intracranial HPC at Rome University Hospital. RESULTS:A total o...
journal_title：World neurosurgery
pub_type： 杂志文章,评审
doi：10.1016/j.wneu.2013.11.009
更新日期：2014-03-01 00:00:00
abstract：:After the completion of an endoscopic spinal surgery fellowship, the next challenge for the newly minted consultant is to set up a viable and sustainable endoscopic practice. A successful practice of endoscopic spine surgery is dependent on several factors, such as anesthetic support; surgical expertise; support for p...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2020.09.056
更新日期：2020-12-01 00:00:00
abstract：OBJECTIVE:The types of cortical venous reflux channels, posterior fossa and pontomesencephalic venous reflux or their connections with the cavernous sinus (CS) are inadequately described in the literature. This study uses angiography, magnetic resonance imaging, and X-ray computed tomography to clarify the possible rou...
journal_title：World neurosurgery
pub_type： 杂志文章
doi：10.1016/j.wneu.2015.05.074
更新日期：2015-10-01 00:00:00
