Detoxification and antioxidant effects of garlic and curcumin in Oreochromis niloticus injected with aflatoxin B₁ with reference to gene expression of glutathione peroxidase (GPx) by RT-PCR.

Abstract:

:The present study aims to investigate the effects of both garlic and curcumin through evaluating their therapeutic properties as antioxidants on liver and kidney functions, hepatic antioxidants and GPx gene expression against aflatoxicosis of O. niloticus. In total, 180 of tilapia were divided into ten groups; T1 represented the negative control fed on a basal diet, and T2 was injected with a single intraperitoneal (i.p.) dose of AFB1 (6 mg/kg b.w.). Fish in T3-T6 were fed on a basal diet supplemented with both garlic (T3 and T4) and curcumin (T5 and T6) at the two concentrations of 10 and 20 g/kg diet, respectively. Fish in T7-T10 groups were injected with AFB1 and fed on the garlic (T7 and T8) and curcumin (T9 and T10) dietaries. The results showed that AFB1 has significant potency for increasing the activity of plasma AST, ALT, creatinine and uric acid values, and hepatic MDA as well as for reducing the concentrations of plasma TP, AL, GL and hepatic activity of TAC, while AFB1 led to up-regulated GPx gene expression when compared to the control (T1). These harmful effects of AFB1 were alleviated due to the garlic and curcumin dietaries in some studied parameters. Garlic reflected the highest induction of gene expression (T7); however, curcumin showed significant down-regulated (T9). These results concluded that the effects of garlic were better than curcumin at the two concentrations and the low concentration of them is more beneficial than the high concentration when it used against AFB1 in O. niloticus.

journal_name

Fish Physiol Biochem

authors

El-Barbary MI

doi

10.1007/s10695-015-0164-4

subject

Has Abstract

pub_date

2016-04-01 00:00:00

pages

617-29

issue

2

eissn

0920-1742

issn

1573-5168

pii

10.1007/s10695-015-0164-4

journal_volume

42

pub_type

杂志文章
  • Hepcidin protects against iron overload-induced inhibition of bone formation in zebrafish.

    abstract::Iron overload increases the risk of osteoporosis, which leads to an increase in the incidences of bone fracture after menopause. In vitro studies have demonstrated that excess iron can inhibit osteoblast activity. Hepcidin, a central regulator of iron homeostasis, prevents iron overload, and thus, it is considered to ...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-018-0568-z

    authors: Jiang Y,Chen B,Yan Y,Zhu GX

    更新日期:2019-02-01 00:00:00

  • Total and free thyroid hormones in plasma of tropical marine teleost fish.

    abstract::Plasma levels of L-thyroxine (T4) and 3,5,3'-triiodo-L-thyronine (T3) and the percentage of plasma T4 and T3 present in the free (dialyzable) form (%FT4 and %FT3) were measured in 16 species (11 families) of tropical marine teleosts from an inshore Barbados reef. Mean plasma T4 varied from 0.2 ng/ml to 42 ng/ml; mean ...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF02180414

    authors: Eales JG,Shostak S

    更新日期:1987-05-01 00:00:00

  • Molecular characterization of heat shock protein 70 gene transcripts during Vibrio harveyi infection of humphead snapper, Lutjanus sanguineus.

    abstract::In the present study, heat shock cognate 70 (HSC70) and inducible heat shock protein 70 (HSP70) gene of humphead snapper, Lutjanus sanguineus, were cloned by rapid amplification of cDNA ends (RACE) technique with the primers designed from the known expressed sequence tags (ESTs) identified from the subtracted cDNA lib...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-011-9487-y

    authors: Zhang X,Pang H,Wu Z,Jian J

    更新日期:2011-12-01 00:00:00

  • The relationship between trace elements in fish otoliths of wild carp and hydrochemical conditions.

    abstract::The trace element composition of the fish otolith is an indicator of biomineralization. In contrast to other skeletal tissue, the otolith retains its entire original structure and does not absorb any elements after the fish dies. Because otoliths in carp degrade very slowly in the dead body, the information it provide...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-008-9294-2

    authors: Gao Y,Feng Q,Ren D,Qiao L,Li S

    更新日期:2010-03-01 00:00:00

  • Gill morphometry of the facultative air-breathing loricariid fish,Hypostomus plecostomus (Walbaum) with, special emphasis on aquatic respiration.

    abstract::Gill respiratory surface area and oxygen consumption during aquatic respiration were measured in the facultative air-breathing loricariid fish,Hypostomus plecostomus. The fish did not surface to breathe atmospheric air in normoxic water; air-breathing was evoked by environmental hypoxia (water oxygen tension=35±2, mmH...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF01875572

    authors: Aparecida Perna S,Fernandes MN

    更新日期:1996-06-01 00:00:00

  • Exposure to different glyphosate formulations on the oxidative and histological status of Rhamdia quelen.

    abstract::Due to the wide use of glyphosate (GLY) in soybean cultivation, their residues in the environment may affect non-target organisms such as fish, developing toxic effects. Despite GLY being widely used in Brazil, there are few studies comparing the effects of commercial formulations in native freshwater fish species. Si...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-015-0150-x

    authors: Murussi CR,Costa MD,Leitemperger JW,Guerra L,Rodrigues CC,Menezes CC,Severo ES,Flores-Lopes F,Salbego J,Loro VL

    更新日期:2016-04-01 00:00:00

  • Oxidative metabolism in a teleost,Anabas testudineus Bloch: effect of testosterone and estradiol-17β on hepatic enzyme activities.

    abstract::Testosterone (T) administration to maleAnabas testudineus significantly stimulated the activities of cytochrome oxidase, α-glycerophosphate dehydrogenase (α-GPDH) and Mg(2+) adenosine triphosphatase (Mg(2+) ATPase) and inhibited lactate dehydrogenase (LDH), cytosolic and mitochondrial malate dehydrogenases (MDH). The ...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF01875607

    authors: Subash Peter MC,Oommen OV

    更新日期:1989-11-01 00:00:00

  • The reduction of lipid-sourced energy production caused by ATGL inhibition cannot be compensated by activation of HSL, autophagy, and utilization of other nutrients in fish.

    abstract::The adipose triglyceride lipase (ATGL) and hormone-sensitive lipase (HSL)-mediated lipolysis play important roles in lipid catabolism. ATGL is considered the central rate-limiting enzyme in the mobilization of fatty acids in mammals. Currently, severe fat accumulation has been commonly detected in farmed fish globally...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-020-00904-7

    authors: Han SL,Liu Y,Limbu SM,Chen LQ,Zhang ML,Du ZY

    更新日期:2020-11-27 00:00:00

  • Profiles of thyrotropin, thyroid hormones, follicular cells and type I deiodinase gene expression during ontogenetic development of tilapia larvae and juveniles.

    abstract::The aims of the present study are to determine whether triiodothyronine (T3) and/or thyroxine (T4) in tilapia larvae is gifted through the mother, and to investigate the change profiles of thyrotropin (TSH), thyroid follicular cells and type I deiodinase (D1) gene expression following larval development. T3 and T4 con...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-014-9950-7

    authors: Hsu CW,Tsai SC,Shen SC,Wu SM

    更新日期:2014-10-01 00:00:00

  • Seasonal and estradiol-17β-stimulated changes in thyroid function of adult Geotria australis, a southern hemisphere lamprey.

    abstract::Measurable in vitro hepatic monodeiodinase activity of the southern hemisphere lamprey, Geotria australis, was present only during the first 5 of the 16 month upstream spawning migration of this species. The production of T3 from T4 in vitro was pH-sensitive, and exhibited typical Michaelis-Menton kinetics. No consist...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF00003372

    authors: Leatherland JF,Macey DJ,Hilliard RW,Leatherland A,Potter IC

    更新日期:1990-09-01 00:00:00

  • Effects of two kinds of fishery drugs on the expressions of GAD and GABA-T mRNA in crucian carp (Carassius auratus gibelio).

    abstract::The objective of this study was to investigate the effects of difloxacin (DIF) and avermectin (AVM) on glutamate decarboxylase (GAD) and GABA-transaminase (GABA-T) in different tissues of crucian carp (Carassius auratus gibelio). After the treatments of DIF and AVM, the mRNA expressions of GAD and GABA-T in different ...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-020-00847-z

    authors: Zhang F,Hu K,Huang J,Tan Z,Ruan J

    更新日期:2020-12-01 00:00:00

  • A study of goldfish oocyte meiosisin vitro: effects of 2,4-dinitrophenol and adenosine-5-triphosphate.

    abstract::Germinal vesicle migration (GVM) and/or dissolution (GVD) were measured in goldfish oocytes, treated with 17α, 20β dihydroxyprogesterone (DHP) and other compounds considered to effect the cytoskeleton and oxidative phosphorylation,in vitro. Administration of DHP reinitiated meiotic maturation, increasing GVM and GVD i...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF02311136

    authors: Habibi HR,Lessman CA

    更新日期:1986-09-01 00:00:00

  • Genetic and structural characterization of the growth hormone gene and protein from tench, Tinca tinca.

    abstract::The analysis of the tench growth hormone gene structure revealed a comparable organization of coding and non-coding regions than other from cyprinid species. Based on the performed mRNA and amino acid sequence alignments, gh tench is related to Asian than to European representatives of Cyprinidae family. Second aim of...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-012-9661-x

    authors: Panicz R,Sadowski J,Drozd R

    更新日期:2012-12-01 00:00:00

  • Intracellular transport of ovalbumin afterin vivo endocytosis in rainbow trout liver.

    abstract::The intracellular handing of a mannose-terminated glycoprotein taken up in rainbow trout liver cells by receptor-mediated endocytosis has been studied. The intracellular transport and degradation of ovalbumin (OA) were studied by means of subcellular fractionation in Nycodenz gradients and by differential centrifugati...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF02265127

    authors: Kindberg GM,Dannevig BH,Andersen KJ,Berg T

    更新日期:1991-04-01 00:00:00

  • Oxidative damage repair by glutamine in fish enterocytes.

    abstract::Fish intestine is very sensitive to oxidative damage. Repair of damaged enterocytes may be involved to restore normal function of fish intestine. However, studies of fish enterocyte repair are scarce. The present study aimed to investigate the potential repair role of glutamine after a H2O2 challenge. In this study, f...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-014-9938-3

    authors: Hu K,Feng L,Jiang W,Liu Y,Jiang J,Li S,Zhou X

    更新日期:2014-10-01 00:00:00

  • Intracellular mediation of GnRH action on GTH release in tilapia.

    abstract::The objective of the present study was to confirm previous results on the mediation of GnRH signal in tilapia by providing evidence from experiments in cultured pituitary cells and from perifusion experiments using a GnRH-antagonist. After 4 days in culture under identical conditions, cells taken from pituitaries of f...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF00004550

    authors: Levavi-Sivan B,Yaron Z

    更新日期:1993-07-01 00:00:00

  • Sperm quality analysis of normal season (NG) and out-season by photoperiod manipulation (PG) of male rainbow trout broodstock (Oncorhynchus mykiss).

    abstract::Sperm quality parameters in rainbow trout (Oncorhynchus mykiss) were investigated during normal season spawning (November-January) and out-season spawning (July-August) treated with artificial photoperiod manipulation. Normal spawning males (n = 15) were kept in an open concrete pond under natural condition. Out-seaso...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-018-0564-3

    authors: Momin M,Memiş D

    更新日期:2018-12-01 00:00:00

  • Effects on the metabolism, growth, digestive capacity and osmoregulation of juvenile of Sub-Antarctic Notothenioid fish Eleginops maclovinus acclimated at different salinities.

    abstract::In this study we assessed the influence of three different environmental salinities (5, 15 and 31 psu during 90 days) on growth, osmoregulation, energy metabolism and digestive capacity in juveniles of the Notothenioid fish Eleginops maclovinus. At the end of experimental time samples of plasma, liver, gill, intestine...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-015-0092-3

    authors: Vargas-Chacoff L,Saavedra E,Oyarzún R,Martínez-Montaño E,Pontigo JP,Yáñez A,Ruiz-Jarabo I,Mancera JM,Ortiz E,Bertrán C

    更新日期:2015-12-01 00:00:00

  • Whole animal transepithelial potential (TEP) of coho salmon during the parr-smolt transformation and effects of thyroxine, prolactin and hypophysectomy.

    abstract::Whole animal transepithelial potentials (TEP) of yearling coho salmon (Oncorhynchus kisutch) in fresh water and after transfer to seawater were recorded throughout parr-smolt transformation (smoltification) from February to August 1984, along with plasma Na(+) and Cl(-) concentrations and osmolality. Based on plasma i...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF02183991

    authors: Iwata M,Nishioka RS,Bern HA

    更新日期:1987-01-01 00:00:00

  • Comparative transcriptome analysis of molecular mechanism underlying gray-to-red body color formation in red crucian carp (Carassius auratus, red var.).

    abstract::Red crucian carp (Carassius auratus red var.) is an ornamental fish with vivid red/orange color. It has been found that the adult body color of this strain forms a gray-to-red change. In this study, skin transcriptomes of red crucian carp are first obtained for three different stages of body color development, named b...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-017-0379-7

    authors: Zhang Y,Liu J,Peng L,Ren L,Zhang H,Zou L,Liu W,Xiao Y

    更新日期:2017-10-01 00:00:00

  • Immunohistochemical investigation of the pituitary of the sturgeon (Acipenser baeri, Chondrostei).

    abstract::An immunohistochemical study of the sturgeon (Acipenser baeri) pituitary was undertaken using antisera directed against hormones from various classes of vertebrates, including the only pituitary hormone available from sturgeon, gonadotrophin. A positive reaction was obtained after application of antisera towards the f...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF01875699

    authors: Pelissero C,Nunez-Rodriguez J,Le Menn F,Kah O

    更新日期:1988-07-01 00:00:00

  • Investigation into effects of antipsychotics on ectonucleotidase and adenosine deaminase in zebrafish brain.

    abstract::Antipsychotic agents are used for the treatment of psychotic symptoms in patients with several brain disorders, such as schizophrenia. Atypical and typical antipsychotics differ regarding their clinical and side-effects profile. Haloperidol is a representative typical antipsychotic drug and has potent dopamine recepto...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-015-0093-2

    authors: Seibt KJ,Oliveira Rda L,Bogo MR,Senger MR,Bonan CD

    更新日期:2015-12-01 00:00:00

  • Tissue distribution of transcription for 29 lipid metabolism-related genes in Takifugu rubripes, a marine teleost storing lipid predominantly in liver.

    abstract::The tissue distribution pattern of lipid is highly diverse among different fish species. Tiger puffer has a special lipid storage pattern, storing lipid predominantly in liver. In order to better understand the lipid physiology in fish storing lipid in liver, the present study preliminarily investigated the tissue dis...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-020-00815-7

    authors: Xu H,Meng X,Jia L,Wei Y,Sun B,Liang M

    更新日期:2020-08-01 00:00:00

  • Changes in levels of GnRH in the brain and pituitary and GTH in the pituitary in male masu salmon, Oncorhynchus masou, from hatching to maturation.

    abstract::Levels of two types of gonadotropin-releasing hormone (salmon GnRH and chicken GnRH-II) in the brain and pituitary, and content of gonadotropin (GTHIβ and IIβ) in the pituitary were measured in male masu salmon from hatching to gonadal maturation for three years in order to clarify the involvement of GnRHs in precocio...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF00004570

    authors: Amano M,Aida K,Okumoto N,Hasegawa Y

    更新日期:1993-07-01 00:00:00

  • Neuropeptides isotocin and arginine vasotocin in urophysis of three fish species.

    abstract::In this study, for the first time, both neuropeptides isotocin (IT) and arginine vasotocin (AVT) have been identified and measured in urophysis, the neurohaemal organ of the caudal neurosecretory system of teleost fish. So far, AVT, but not IT, was quantified by radioimmunoassay (RIA) in urophysis of several fish spec...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-012-9746-6

    authors: Gozdowska M,Ślebioda M,Kulczykowska E

    更新日期:2013-08-01 00:00:00

  • Annual patterns of ocular melatonin level in the female grass puffer, Takifugu alboplumbeus: possible involvement in seasonal reproductive response.

    abstract::The aim of this study was to investigate the expression patterns of ocular melatonin in the annual reproductive cycle of the female grass puffer. Spawning season of the female grass puffer is from June to July in Jeju, South Korea. Time-resolved fluoroimmunoassay revealed that levels of ocular melatonin, which show an...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-019-00749-9

    authors: Kim BH,Hur SP,Hyeon JY,Yamashina F,Takemura A,Lee YD

    更新日期:2020-06-01 00:00:00

  • The cytochrome P450 system of atlantic salmon (Salmo salar): I. Basal properties and induction of P450 1A1 in liver of immature and mature fish.

    abstract::The major components of the cytochrome P450 (P450) system in liver microsomes of Atlantic salmon were studied using spectrophotometric, catalytic and immunochemical techniques. In juvenile fish sampled during the winter season, high basal activities of 7-ethoxyresorufin O-deethylase (EROD) were found. The Km for 7-eth...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF02265154

    authors: Goksøyr A,Larsen HE

    更新日期:1991-12-01 00:00:00

  • Development of digestive enzymes in larvae of Mayan cichlid Cichlasoma urophthalmus.

    abstract::The development of digestive enzymes during the early ontogeny of the Mayan cichlid (Cichlasoma urophthalmus) was studied using biochemical and electrophoretic techniques. From yolk absorption (6 days after hatching: dah), larvae were fed Artemia nauplii until 15 dah, afterward they were fed with commercial microparti...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/s10695-010-9431-6

    authors: López-Ramírez G,Cuenca-Soria CA,Alvarez-González CA,Tovar-Ramírez D,Ortiz-Galindo JL,Perales-García N,Márquez-Couturier G,Arias-Rodríguez L,Indy JR,Contreras-Sánchez WM,Gisbert E,Moyano FJ

    更新日期:2011-03-01 00:00:00

  • Proteolysis by juvenile sea bass (Dicentrarchus labrax) gastrointestinal enzymes as a method for the evaluation of feed proteins.

    abstract::Protein digestibility by gastrointestinal homogenates of Dicentrarchus labrax, was investigated in 5 feeds in relation to their amino acids composition and their ability to sustain growth of D. labrax post larval juveniles. Gastric proteolysis was found to contribute <25% of the total proteolytic capacity. Correlation...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF00003377

    authors: Lindner P,Eshell A,Kolkovski S,Tandler A,Harpaz S

    更新日期:1995-10-01 00:00:00

  • Cardiovascular, respiratory, and blood adjustments to hypoxia in the Japanese eel,Anguilla japonica.

    abstract::The cardioventilatory performance of the Japanese eel,Anguilla japonica, was evaluated during acute exposure to hypoxia. The eel became an oxygen conformer as ambient PO2 fell below the critical value of 110 mmHg. Although arterial and venous PO2 also fell progressively, the arterial O2 content remained constant down ...

    journal_title:Fish physiology and biochemistry

    pub_type: 杂志文章

    doi:10.1007/BF02264086

    authors: Chan DK

    更新日期:1986-10-01 00:00:00