Abstract:
BACKGROUND AND AIMS:Double-guidewire technique (DWT) has been successfully performed by experts in difficult biliary cannulation as an advanced technique. This study aimed to define the learning curve and safety of DWT by trainees during hands-on endoscopic retrograde cholangiopancreatography (ERCP) training. METHODS:Patients were eligible for inclusion in the study if the biliary cannulation was difficult and the pancreatic duct was inadvertently cannulated. DWT was performed by two trainees randomly under trainers' guidance. The primary outcome was the success rate of DWT biliary cannulation of trainees. Cumulative sum analysis was used to generate visual learning curves. RESULTS:A total of 60 patients with difficult cannulation were enrolled. The main indications for ERCP were common bile duct stones (65%) and biliary stricture (31.7%). The learning curve analysis showed that to achieve a 70% rate of successful DWT, 12 procedures were needed for trainee A and 15 for trainee B. Higher targeted success rate of DWT could be achieved if the number of DWT procedures increased. Compared with the early stage of learning DWT (case 1 to 15 for each trainee), trainees had significantly higher DWT success rate in the late stage (36.7% [11/30] vs 80% [24/30], P = 0.001). The final success rate of cannulation was 98.3% (59/60). The overall rate of post-ERCP pancreatitis and adverse events was 6.7% (4/60) and 8.3% (5/60), respectively. CONCLUSIONS:Double-guidewire technique was safely performed by two novel trainees during hands-on ERCP training. Fifteen procedures may be enough for trainees to achieve the competency of performing DWT. (Clinicaltrials.gov number: NCT03707613).
journal_name
J Gastroenterol Hepatoljournal_title
Journal of gastroenterology and hepatologyauthors
Wang X,Ren G,Xi Y,Luo H,Liang S,Wang B,Tao Q,Luo B,Qin Q,Farrell JJ,Guo X,Wu K,Pan Ydoi
10.1111/jgh.15120subject
Has Abstractpub_date
2020-05-30 00:00:00eissn
0815-9319issn
1440-1746pub_type
杂志文章abstract::T regulatory cells (Tregs) play an important role in the regulation of autoimmunity, autoinflammation, allergic diseases, infection, and the tumor environment. Different subsets are characterized that use a number of regulatory mechanisms. Tregs can influence the progression of inflammatory bowel disease and the devel...
journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章,评审
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journal_title:Journal of gastroenterology and hepatology
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doi:10.1046/j.1440-1746.2003.03166.x
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journal_title:Journal of gastroenterology and hepatology
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2006.04612.x
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journal_title:Journal of gastroenterology and hepatology
pub_type: 临床试验,杂志文章,随机对照试验
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journal_title:Journal of gastroenterology and hepatology
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doi:10.1046/j.1440-1746.2003.03038.x
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
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pub_type: 杂志文章,评审
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abstract:BACKGROUND AND AIM:The prevalence of ulcerative colitis (UC) is increasing steadily in Japan. In Western countries, a bimodal distribution, with UC onset peaks in youth and middle age, is observed, and smoking cessation is reported as a risk factor for UC. However, there are few reports on a bimodal distribution of ons...
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pub_type: 杂志文章
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更新日期:2014-08-01 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章,多中心研究
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pub_type: 杂志文章,meta分析
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pub_type: 杂志文章
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章
doi:10.1111/j.1440-1746.2011.06771.x
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journal_title:Journal of gastroenterology and hepatology
pub_type: 临床试验,杂志文章,随机对照试验
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pub_type: 杂志文章
doi:10.1046/j.1440-1746.2003.03180.x
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章,评审
doi:10.1111/j.1440-1746.1992.tb01496.x
更新日期:1992-11-01 00:00:00
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更新日期:2018-02-06 00:00:00
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journal_title:Journal of gastroenterology and hepatology
pub_type: 杂志文章,评审
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pub_type: 杂志文章
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更新日期:2013-02-01 00:00:00
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更新日期:2019-01-01 00:00:00