Abstract:
BACKGROUND:Little has been known regarding the correlates of severe insomnia in major depressive disorder (MDD). This post-hoc analysis aimed to examine the sociodemographic and clinical correlates of severe insomnia in psychotropic drug-free, Asian adult outpatients with MDD. METHODS:Participants were psychotropic drug-free patients with MDD, aged 18-65 years. By using the Symptom Checklist-90 Items, Revised (SCL-90-R), a score of 4 (severe distress) on any one of three insomnia items was defined as severe insomnia. Other measures included the Montgomery-Asberg Depression Rating Scale (MADRS), the Fatigue Severity Scale (FSS), the nine psychopathology subscales of SCL-90-R, the Physical and Mental Component Summaries of Short Form Health Survey (SF-36 PCS and SF-36 MCS), and the Sheehan Disability Scale (SDS). RESULTS:Of 528 participants, their mean age being 39.5 (SD=13.26) years, 64.2% were females, and 239 (45.3%) had severe insomnia. The logistic regression model revealed that low educational qualifications (less than secondary school completion), high SCL-90-R Depression scores, high SCL-90-R Anxiety scores, and low SF-36 PCS scores were independently correlated with severe insomnia (p's<.05). LIMITATIONS:Insomnia was determined only by the patient's distress. Middle insomnia was not assessed. Psychotropic drug-free patients with MDD are not commonly seen in psychiatric practice. CONCLUSION:Severe insomnia is common in patients with MDD. It is closely related with low educational qualification, subjective depression and anxiety severity, and poor physical health. These findings may implicate the treatment of comorbid MDD and severe insomnia, for example, sleep hygiene education, pharmacological treatment.
journal_name
J Affect Disordjournal_title
Journal of affective disordersauthors
Srisurapanont M,Likhitsathian S,Chua HC,Udomratn P,Chang S,Maneeton N,Maneeton B,Chen CH,Shih-Yen Chan E,Bautista D,Bin Sulaiman AHdoi
10.1016/j.jad.2015.06.032subject
Has Abstractpub_date
2015-11-01 00:00:00pages
26-31eissn
0165-0327issn
1573-2517pii
S0165-0327(15)30274-3journal_volume
186pub_type
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.01.003
更新日期:2009-10-01 00:00:00
abstract:BACKGROUND:Social networking sites (SNSs), which provide abundant social comparison opportunities, are ubiquitous around the world, especially among adolescents. In China, Qzone stands out as the most popular SNS. Due to the opportunity it provides for meticulous self-presentation, SNS may give the impression that othe...
journal_title:Journal of affective disorders
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abstract:OBJECTIVES:Disturbances in sleep and waking patterns are highly prevalent during mood episodes in bipolar disorder. The question remains whether these disturbances persist during phases of euthymia and whether they are heritable traits of bipolar disorder. The current study investigates objective sleep measures in a la...
journal_title:Journal of affective disorders
pub_type: 杂志文章
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abstract:BACKGROUND:Existing literature on the impact of the course of maternal distress symptoms in the perinatal period and beyond has mainly focused on one source of distress (e.g., anxiety or depression) and only selected aspects of child development. This study examined the relative impact of trajectories of maternal depre...
journal_title:Journal of affective disorders
pub_type: 杂志文章
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更新日期:2019-04-01 00:00:00
abstract::Eighty-six patients suffering from nonpsychotic unipolar major depressive disorder, according to Research Diagnostic Criteria, were rated on a modified Hamilton Rating Scale for Depression (HRS). All completed the self-rating Beck Depression Inventory (BDI). Distal colon motility (dcm) studies, performed in all the pa...
journal_title:Journal of affective disorders
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更新日期:1983-02-01 00:00:00
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journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
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更新日期:1985-11-01 00:00:00
abstract:BACKGROUND:Confusion abounds when differentiating the diagnoses of bipolar disorder (BD) from borderline personality disorder (BPD). This study explored the relative clinical utility of affective instability and self-report personality trait measures for accurate identification of BD and BPD. METHODS:Receiver operator...
journal_title:Journal of affective disorders
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doi:10.1016/j.jad.2018.11.079
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abstract::An increasing number of computerised transdiagnostic cognitive behavioural therapy programs (TD-cCBT) have been developed in the past decade, but there are no meta-analyses to explore the efficacy of these programs, nor moderators of the effects. The current meta-analysis focused on studies evaluating TD-cCBT interven...
journal_title:Journal of affective disorders
pub_type: 杂志文章,meta分析,评审
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abstract::A clinical study was conducted to examine the effects of depression on cardiac autonomic control. Cardiac autonomic control was measured in 26 nonmedicated patients (19 females) suffering from Major Depression, melancholic type, and in 26 age- and sex-matched normal controls. We measured heart rate and high frequency ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/s0165-0327(97)00164-x
更新日期:1998-03-01 00:00:00
abstract:BACKGROUND:Bipolar disorder (BD) broadly affects brain structure, in particular areas involved in emotion processing and cognition. In the last years, the psychiatric field's interest in machine learning approaches has been steadily growing, thanks to the potentiality of automatically discriminating patients from healt...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2019.06.019
更新日期:2019-09-01 00:00:00
abstract:BACKGROUND:Various associations between monthly Google search volumes (MGSVs) and monthly suicide rates (MSRs) have been reported. However, these studies often analyzed a limited number of search terms using suboptimal statistical methods. While controlling for spurious associations, this study examined a wide array of...
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pub_type: 杂志文章
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更新日期:2020-02-01 00:00:00
abstract:BACKGROUND:Since its introduction in DSM-III, the validity of dysthymia has been debated. Our objective is to further examine the concept of dysthymia in an outpatient sample, and explore whether its constituents can be meaningfully apportioned. METHODS:318 patients attending the Black Dog Institute Depression Clinic ...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2012.05.051
更新日期:2012-12-20 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,随机对照试验
doi:10.1016/j.jad.2011.11.043
更新日期:2012-02-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.11.027
更新日期:2016-02-01 00:00:00
abstract:INTRODUCTION:Considerable concern persists on tobacco use during perinatal periods. No study has simultaneously investigated the longitudinal association of paternal smoking with maternal and paternal depressive and anxiety symptoms during perinatal periods. METHODS:In this prospective study, 533 couples (pregnant wom...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2015.12.027
更新日期:2016-03-15 00:00:00
abstract:BACKGROUND:A heightened sensitivity to social rejection might contribute towards the interpersonal difficulties and symptoms that characterise Anorexia Nervosa (AN). This paper examines the effect of Cognitive Bias Modification for Interpretation biases (CBM-I) training on a negative interpretation bias for ambiguous s...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2017.11.089
更新日期:2018-02-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2018.08.030
更新日期:2019-01-01 00:00:00
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journal_title:Journal of affective disorders
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.10.008
更新日期:2010-06-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2008.07.013
更新日期:2009-04-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
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更新日期:1990-01-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章,评审
doi:10.1016/j.jad.2005.08.013
更新日期:2005-12-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2009.02.012
更新日期:2009-11-01 00:00:00
abstract:BACKGROUND:In recent decades, the role of brain-derived neurotrophic factor (BDNF) in depression has received intensive attention. However, the relationship between proBDNF and depression has not been clearly elucidated. METHODS:Forty drug-free women patients diagnosed with major depression and 50 healthy female contr...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2013.03.002
更新日期:2013-09-25 00:00:00
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journal_title:Journal of affective disorders
pub_type: 临床试验,杂志文章
doi:10.1016/s0165-0327(02)00085-x
更新日期:2003-09-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2010.01.072
更新日期:2010-09-01 00:00:00
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journal_title:Journal of affective disorders
pub_type: 杂志文章
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更新日期:2002-05-01 00:00:00
abstract:BACKGROUND:Depression is characterized by gender-specific distinctions, with women being affected more often than men. The Patient Health Questionnaire-9 (PHQ-9) is frequently used to assess depression in primary healthcare. Previous research has yielded heterogeneous findings on the factor structure, and little is kno...
journal_title:Journal of affective disorders
pub_type: 杂志文章
doi:10.1016/j.jad.2014.08.053
更新日期:2015-01-01 00:00:00