Treatment of neonatal fungal infective endocarditis with recombinant tissue plasminogen: activator in a low birth weight infant case report and review of the literature.

Abstract:

:With advances in medical sciences, an increase in survival rates of low birth weight; increased incidence in use of catheter and antibiotics, and total parenteral nutrition are reported, therefore, the rate of fungal infections in late and very late onset neonatal sepsis have increased. Although fungal endocarditis rarely occur in newborns, it has a high morbidity and mortality. Antifungal therapy is often insufficient in cases who develop fungal endocarditis and surgical treatment is not preferred due to its difficulty and high mortality. Herein, fungal endocarditis in a preterm newborn treated with single-dose recombinant tissue plasminogen activator in addition to antifungal therapy is presented and relevant literature has been reviewed. The vegetation completely disappeared following treatment and no complication was observed.

journal_name

Mycoses

journal_title

Mycoses

authors

Babayigit A,Cebeci B,Buyukkale G,Semerci SY,Bornaun H,Oztarhan K,Gokce M,Cetinkaya M

doi

10.1111/myc.12359

subject

Has Abstract

pub_date

2015-10-01 00:00:00

pages

578-81

issue

10

eissn

0933-7407

issn

1439-0507

journal_volume

58

pub_type

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