PSMA whole-body tumor burden in primary staging and biochemical recurrence of prostate cancer.

abstract：PURPOSE:In the era of precision medicine, patient-specific dose calculation using Monte Carlo (MC) simulations is deemed the gold standard technique for risk-benefit analysis of radiation hazards and correlation with patient outcome. Hence, we propose a novel method to perform whole-body personalized organ-level dosime...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Akhavanallaf A,Shiri I,Arabi H,Zaidi H

更新日期：2020-09-01 00:00:00

abstract：PURPOSE:4-[(18)F]-ADAM is a potent serotonin transport imaging agent. We studied its toxicity in rats and radiation dosimetry in monkeys before human studies are undertaken. METHODS:Single and multiple-dosage toxicity studies were conducted in Sprague-Dawley rats. Male and female rats were injected intravenously with ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Huang YY,Ma KH,Tseng TW,Chou TK,Ng H,Mirsalis JC,Fu YK,Chu TC,Huang WS,Shiue CY

更新日期：2010-03-01 00:00:00

abstract：PURPOSE:The role of brain FDG-PET in patients with lung cancer and brain metastases remains unclear. Here, we sought to determine the prognostic significance of whole-body PET/CT plus brain PET/MR in predicting the time to neurological progression (nTTP) and overall survival (OS) in this patient group. METHODS:Of 802 ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ho KC,Toh CH,Li SH,Liu CY,Yang CT,Lu YJ,Su TP,Wang CW,Yen TC

更新日期：2019-02-01 00:00:00

abstract：PURPOSE:The goal of this study is to determine the technical accuracy of segmental perfusion parameters assessed with quantitative cardiac PET imaging in the evaluation of coronary artery disease (CAD) in patients with stable angina. METHODS:A cohort of patients who participated in the EVINCI protocol underwent an eva...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Berti V,Sciagrà R,Neglia D,Pietilä M,Scholte AJ,Nekolla S,Rouzet F,Pupi A,Knuuti J

更新日期：2016-07-01 00:00:00

abstract：PURPOSE:We previously reported in a small series of patients that (99m)Tc-3,3-diphosphono-1,2-propanodicarboxylic acid ((99m)Tc-DPD) scintigraphy tested positive in transthyretin-related (TTR) (both mutant and wild-type) but not in primary (AL) amyloidotic cardiomyopathy (AC). We extended our study to a larger cohort o...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Rapezzi C,Quarta CC,Guidalotti PL,Longhi S,Pettinato C,Leone O,Ferlini A,Salvi F,Gallo P,Gagliardi C,Branzi A

更新日期：2011-03-01 00:00:00

abstract：:Oesophageal scintigraphy has been used for more than 25 years and allows quantifiable, safe, rapid, non-invasive and well-tolerated assessment of oesophageal transit time and function. As technology improves, more complex image analysis is becoming possible. Many studies have addressed its usefulness in assessing oeso...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Stacey B,Patel P

更新日期：2002-09-01 00:00:00

abstract：PURPOSE:Tumour hypoxia is linked to treatment resistance. Positron emission tomography (PET) using hypoxia tracers such as fluoroazomycin arabinoside (FAZA) may allow identification of patients with hypoxic tumours and the monitoring of the efficacy of hypoxia-targeting treatment. Since hypoxia PET is characterized by ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Busk M,Mortensen LS,Nordsmark M,Overgaard J,Jakobsen S,Hansen KV,Theil J,Kallehauge JF,D'Andrea FP,Steiniche T,Horsman MR

更新日期：2013-01-01 00:00:00

abstract：:Radionuclide imaging of cardiac function represents a number of well-validated techniques for accurate determination of right (RV) and left ventricular (LV) ejection fraction (EF) and LV volumes. These first European guidelines give recommendations for how and when to use first-pass and equilibrium radionuclide ventri...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Hesse B,Lindhardt TB,Acampa W,Anagnostopoulos C,Ballinger J,Bax JJ,Edenbrandt L,Flotats A,Germano G,Stopar TG,Franken P,Kelion A,Kjaer A,Le Guludec D,Ljungberg M,Maenhout AF,Marcassa C,Marving J,McKiddie F,Schaefer

更新日期：2008-04-01 00:00:00

abstract：PURPOSE:Metabotropic glutamate receptor subtype 5 (mGluR5) dysfunction has been implicated in several disorders. [(11)C]ABP688, a positron emission tomography (PET) ligand targeting mGluR5, could be a valuable tool in the development of novel therapeutics for these disorders by establishing in vivo drug occupancy. Due ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： DeLorenzo C,Milak MS,Brennan KG,Kumar JS,Mann JJ,Parsey RV

更新日期：2011-06-01 00:00:00

abstract：PURPOSE:Epicardial adipose tissue (EAT) has been linked to coronary artery disease (CAD) and coronary microvascular dysfunction. However, its injurious effect may also impact the underlying myocardium. This study aimed to determine the impact of obesity on the quantitative relationship between left ventricular mass (LV...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Bakkum MJ,Danad I,Romijn MA,Stuijfzand WJ,Leonora RM,Tulevski II,Somsen GA,Lammertsma AA,van Kuijk C,van Rossum AC,Raijmakers PG,Knaapen P

更新日期：2015-09-01 00:00:00

abstract：:Oxygen (O(2)) inhalation after acute myocardial ischaemia has long been a part of standard therapy in cardiology. It has also been demonstrated that therapeutic hyperoxia diminishes myocardial stunning. The aim of this pilot study was to investigate whether the uptake kinetics of the myocardial perfusion agent technet...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Basoglu T,Yapici O,Aksakal E,Sahin M,Canbaz F,Albayrak S,Yesildag O

更新日期：2002-11-01 00:00:00

abstract：PURPOSE/BACKGROUND:[18F]fluoroethylcholine (18FECH) has been shown to be a valuable PET-tracer in recurrent prostate cancer (PCa), but still has limited accuracy. RM2 is a gastrin-releasing peptide receptor (GRPr) antagonist that binds to GRPr on PCa cells. Recent studies suggest that GRPr imaging with PET/CT is a prom...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Wieser G,Popp I,Christian Rischke H,Drendel V,Grosu AL,Bartholomä M,Weber WA,Mansi R,Wetterauer U,Schultze-Seemann W,Meyer PT,Jilg CA

更新日期：2017-08-01 00:00:00

abstract：PURPOSE:To investigate dynamic ictal perfusion changes during temporal lobe epilepsy (TLE). METHODS:We investigated 37 patients with TLE by ictal and interictal SPECT. All ictal injections were performed within 60 s of seizure onset. Statistical parametric mapping was used to analyse brain perfusion changes and tempor...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dupont P,Zaknun JJ,Maes A,Tepmongkol S,Vasquez S,Bal CS,Van Paesschen W,Carpintiero S,Locharernkul C,Dondi M

更新日期：2009-05-01 00:00:00

abstract：PURPOSE:(32)P-chromic phosphate colloid treatments of astrocytoma and craniopharyngioma cystic brain tumours in paediatric patients are conventionally based on a sphere model under the assumption of uniform uptake. The aims of this study were to determine the distribution of the absorbed dose delivered by (32)P on a pa...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Denis-Bacelar AM,Romanchikova M,Chittenden S,Saran FH,Mandeville H,Du Y,Flux GD

更新日期：2013-10-01 00:00:00

abstract：PURPOSE:To evaluate the diagnostic potential of PET/MRI with [(18)F]FDG in recurrent ovarian and cervical cancer in comparison to PET/CT. METHODS:A group of 19 patients with suspected recurrence of pelvic malignancies (ovarian cancer, 11 patients; cervical cancer, 8 patients) scheduled for an [(18)F]FDG PET/CT were su...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Beiderwellen K,Grueneisen J,Ruhlmann V,Buderath P,Aktas B,Heusch P,Kraff O,Forsting M,Lauenstein TC,Umutlu L

更新日期：2015-01-01 00:00:00

abstract：PURPOSE:The aim of this study was to investigate the effect of positron range on visualization and quantification in (18)F, (68)Ga and (124)I positron emission tomography (PET)/CT of lung-like tissue. METHODS:Different sources were measured in air, in lung-equivalent foams and in water, using a clinical PET/CT and a m...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kemerink GJ,Visser MG,Franssen R,Beijer E,Zamburlini M,Halders SG,Brans B,Mottaghy FM,Teule GJ

更新日期：2011-05-01 00:00:00

abstract：PURPOSE:To assess the role of single-photon emission computed tomography with computed tomography (SPECT-CT) for the identification of sentinel lymph nodes (SLNs) in patients with early stage (T1-T2) oral cancer and a clinically negative neck (cN0). METHODS:In addition to planar lymphoscintigraphy, SPECT-CT was perfor...

journal_title：European journal of nuclear medicine and molecular imaging

authors： den Toom IJ,van Schie A,van Weert S,Karagozoglu KH,Bloemena E,Hoekstra OS,de Bree R

更新日期：2017-06-01 00:00:00

abstract：PURPOSE:To evaluate, in patients with chest pain, the diagnostic value of ST elevation (STE) in lead aVR during stress testing prior to (99m) Tc-sestamibi scanning correlating ischaemic territory with angiographic findings. METHODS:Consecutive patients attending for (99m) Tc-sestamibi myocardial perfusion imaging (MPI...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Neill J,Shannon HJ,Morton A,Muir AR,Harbinson M,Adgey JA

更新日期：2007-03-01 00:00:00

abstract：PURPOSE:The washout rate (WR) has been used in (123)I-metaiodobenzylguanidine (MIBG) imaging to evaluate cardiac sympathetic innervation. However, WR varies depending on the time between the early and late MIBG scans. Late scans are performed at either 3 or 4 hours after injection of MIBG. The aim of this study was to ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Okuda K,Nakajima K,Sugino S,Kirihara Y,Matsuo S,Taki J,Hashimoto M,Kinuya S

更新日期：2016-02-01 00:00:00

abstract：PURPOSE:To characterise tissue sites of immune activation and HIV replication we performed FDG-PET in ART-treated and ART-naive HIV-infected individuals. Specific aims were to establish whether HIV-infected patients can be differentiated on the basis of the detection of specific locations of viral replication, even in ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Lucignani G,Orunesu E,Cesari M,Marzo K,Pacei M,Bechi G,Gori A,Gaito S,Clerici M,Chiti A

更新日期：2009-04-01 00:00:00

abstract：PURPOSE:Interim 2-[(18)F]fluoro-2-deoxy-D-glucose positron emission tomography (FDG PET) has shown to be an accurate predictor of prognosis in Hodgkin's lymphoma (HL). However, FDG PET response criteria are a matter of ongoing debate. The aim of this study was to confirm the prognostic value of interim PET/CT in HL pat...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Le Roux PY,Gastinne T,Le Gouill S,Nowak E,Bodet-Milin C,Querellou S,Mahe B,Dubruille V,Blin N,Salaun PY,Bodere-Kraeber F

更新日期：2011-06-01 00:00:00

abstract：:Jérôme Barriere was inadvertently missing in the original version of this article. He has participated to the study design, protocol writing and inclusion of a significant number of patients. ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Humbert O,Bourg V,Mondot L,Gal J,Bondiau PY,Fontaine D,Barriere J,Saada-Bouzid E,Paquet M,Chardin D,Almairac F,Vandenbos F,Darcourt J

更新日期：2019-07-01 00:00:00

abstract：:Dynamic PET (dPET) studies have been used until now primarily within research purposes. Although it is generally accepted that the information provided by dPET is superior to that of conventional static PET acquisitions acquired usually 60 min post injection of the radiotracer, the duration of dynamic protocols, the l...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Dimitrakopoulou-Strauss A,Pan L,Sachpekidis C

更新日期：2021-01-01 00:00:00

abstract：PURPOSE:Firefly luciferase catalyzes the oxidative decarboxylation of D: -luciferin to oxyluciferin in the presence of cofactors, producing bioluminescence. This reaction is used in optical bioluminescence-based molecular imaging approaches to detect the expression of the firefly luciferase reporter gene. Biokinetics a...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Berger F,Paulmurugan R,Bhaumik S,Gambhir SS

更新日期：2008-12-01 00:00:00

abstract：:Cardiac sarcoidosis (CS) is a rare and potentially life-threatening disease that causes conduction disturbance, systolic dysfunction, and most notably sudden cardiac death. Accurate diagnosis of CS is thus mandatory; however, a reliable approach that enables diagnosis of CS with high sensitivity and specificity has ye...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Ohira H,Tsujino I,Yoshinaga K

更新日期：2011-09-01 00:00:00

abstract：:It has been suggested that determination of differential renal function (DRF)using technetium-99m dimercaptosuccinic acid (DMSA) may lead to overestimation of the function of an obstructed kidney in patients with excretion abnormalities owing to pelvic retention of DMSA. Recently published guidelines have recommended ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Kabasakal L,Turkmen C,Ozmen O,Alan N,Onsel C,Uslu I

更新日期：2002-11-01 00:00:00

abstract：PURPOSE:Investigate whether 18F-FDG PET-CT has the potential to predict the major pathologic response (MPR) to neoadjuvant sintilimab in resectable NSCLC patients, and the potential of sifting patients who probably benefit from immunotherapy. METHODS:Treatment-naive patients with resectable NSCLC (stage IA-IIIB) recei...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Tao X,Li N,Wu N,He J,Ying J,Gao S,Wang S,Wang J,Wang Z,Ling Y,Tang W,Zhang Z

更新日期：2020-05-01 00:00:00

abstract：BACKGROUND:(131)Iodine (I131)-metaiodobenzylguanidine (mIBG) is a radionuclide-based treatment option for metastatic gastrointestinal-pancreatic neuroendocrine tumours (GEP NET). This study aimed at identifying prognostic indicators of long-term outcome based on initial evaluation following a first mIBG treatment (7400...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Mulholland N,Chakravartty R,Devlin L,Kalogianni E,Corcoran B,Vivian G

更新日期：2015-12-01 00:00:00

abstract：PURPOSE:To quantify the severity of 2019 novel coronavirus disease (COVID-19) on chest CT and to determine its relationship with laboratory parameters. METHODS:Patients with real-time fluorescence polymerase chain reaction (RT-PCR)-confirmed COVID-19 between January 01 and February 18, 2020, were included in this stud...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Zhang B,Zhang J,Chen H,Chen L,Chen Q,Li M,Chen Z,You J,Yang K,Zhang S

更新日期：2020-08-01 00:00:00

abstract：:Physiologically increased pancreatic uptake at the head/uncinate process is observed in more than one-third of patients after injection of one of the three (68)Ga-labelled octreotide-based peptides used for somatostatin (sst) receptor (r) imaging. There are minor differences between these (68)Ga-sstr-binding peptides ...

journal_title：European journal of nuclear medicine and molecular imaging

authors： Virgolini I,Gabriel M,Kroiss A,von Guggenberg E,Prommegger R,Warwitz B,Nilica B,Roig LG,Rodrigues M,Uprimny C

更新日期：2016-10-01 00:00:00