Abstract:
:The active and passive mechanical behavior of a cosmetic tightening product for skin anti-aging is investigated based on a wide range of in vivo and in vitro measurements. The experimental data are used to inform a numerical model of the attained cosmetic effect, which is then implemented in a commercial finite-element framework and used to analyze the mechanisms that regulate the biomechanical interaction between the native tissue and the tightening film. Such a film reduces wrinkles and enhances skin consistency by increasing its stiffness by 48-107% and reducing inelastic, non-recoverable deformations (-47%). The substrate deformability influences both the extent of tightening and the reduction of wrinkle amplitude. The present findings allow, for the first time, to rationalize the mechanisms of action of cosmetic products with a tightening action and provide quantitative evidence for further optimization of this fascinating class of biomaterials.
journal_name
Acta Biomaterjournal_title
Acta biomaterialiaauthors
Pensalfini M,Rotach M,Hopf R,Bielicki A,Santoprete R,Mazza Edoi
10.1016/j.actbio.2020.08.027subject
Has Abstractpub_date
2020-10-01 00:00:00pages
299-316eissn
1742-7061issn
1878-7568pii
S1742-7061(20)30487-6journal_volume
115pub_type
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