Asymmetric Borane Reduction of Prochiral Ketones Catalyzed By Helical Poly[(S)-3-vinyl-2,2'-dihydroxy-1,1'-binaphthyl].

Abstract:

:The application of helical poly[(S)-3-vinyl-2,2'-dihydroxy-1, 1'-binaphthyl] (L*) in the asymmetric borane reduction of prochiral ketones was studied. The results showed that L* had excellent catalytic activity as well as enantioselectivity, giving up to 96% yield and up to 99% enantiomeric excess (ee) of the corresponding secondary alcohol at 25 °C. Moreover, L* can be easily recovered and reused without loss of catalytic activity.

journal_name

Chirality

journal_title

Chirality

authors

Qin G,Chen Y,Yang L,Yang N,Yang Z

doi

10.1002/chir.22459

subject

Has Abstract

pub_date

2015-07-01 00:00:00

pages

422-4

issue

7

eissn

0899-0042

issn

1520-636X

journal_volume

27

pub_type

杂志文章