Expression of p16INK4 and Rb Genes in Cervical Neoplasm.

abstract：OBJECTIVE:This study aimed to report 2 cases of squamous cell carcinoma (SCC) of the vulva, arising from unusual subepithelial locations. MATERIALS AND METHODS:The first case was of an 85-year-old woman with a 65-year history of a mass in the left labium majus. The second case was of a 54-year-old woman who presented ...

journal_title：Journal of lower genital tract disease

authors： Scurry JP,Yu TT,Otton GR

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to compare cervical cytologic and histologic findings between women using depot-medroxyprogesterone acetate (DMPA) and oral contraceptives (OCs) referred for colposcopy and to determine whether there were differences in the occurrence of false-positive cytologic finding between the 2 contrace...

journal_title：Journal of lower genital tract disease

authors： Clark MK,Stockdale CK,Railsback L,Nichols S

更新日期：2011-07-01 00:00:00

abstract：:A 17-year-old adolescent girl developed severe toxic epidermal necrolysis after inhalation of methamphetamine. Recovery was complicated by vaginal synechiae and occlusion necessitating surgery. ...

journal_title：Journal of lower genital tract disease

authors： Rowan DM,Jones RW,Oakley A,de Silva H

更新日期：2010-10-01 00:00:00

abstract：OBJECTIVES:The aims of the study were to assess the clinical and histopathological characteristics of a comprehensive cohort of women with vulvovaginal melanoma (VVM) treated at our institution and to study the treatment response of checkpoint inhibitors in this patient cohort. MATERIALS AND METHODS:This is a retrospe...

journal_title：Journal of lower genital tract disease

authors： Wohlmuth C,Wohlmuth-Wieser I,Laframboise S

更新日期：2020-11-24 00:00:00

abstract：OBJECTIVE:Given the high prevalence of cervical intraepithelial neoplasia (CIN) grade 2/3 among HIV-infected women, we sought to examine the relationship between CIN 2/3 and HIV-1 genital shedding among women on highly active antiretroviral therapy (HAART). MATERIALS AND METHODS:Paired plasma and cervical wick specime...

journal_title：Journal of lower genital tract disease

authors： Huchko MJ,Woo V,Liegler T,Leddy A,Smith-McCune K,Sawaya GF,Bukusi EA,Cohen CR

更新日期：2013-07-01 00:00:00

abstract：OBJECTIVE:To evaluate the ability of collecting the Affirm VP-III test sample using the residual vaginal discharge found on the speculum. METHODS AND METHODS:One hundred nine symptomatic women (≥18 y) participated in this study. During pelvic examination, vaginal fluid was collected onto 3 swabs for office-based diagn...

journal_title：Journal of lower genital tract disease

authors： Mulhem E,Boyanton BL Jr,Robinson-Dunn B,Ebert C,Dzebo R

更新日期：2014-10-01 00:00:00

abstract：OBJECTIVE:Studies on the development of the embryological and fetal development of the cervix and the vagina are rare and mostly go back to the first decades of the last century. The aims of this review were to present the latest knowledge concerning the developmental origin of cervical and vaginal epithelium and to po...

journal_title：Journal of lower genital tract disease

authors： Reich O,Fritsch H

更新日期：2014-10-01 00:00:00

abstract：BACKGROUND:The authors' objective was to determine retrospectively the methods used to follow up atypical glandular cells of undetermined significance (AGUS) on Papanicolaou smears and to evaluate the effectiveness of those methods. MATERIAL AND METHODS:The charts of all patients with AGUS smears obtained between Febr...

journal_title：Journal of lower genital tract disease

authors： Landry MS,Julian TM

更新日期：1997-04-01 00:00:00

abstract：OBJECTIVE:To compare rates of cervical intraepithelial neoplasia grade 3 or greater (CIN3+) between women aged 21 to 24 and women aged 25 or older undergoing a see-and-treat strategy for high-grade squamous intraepithelial lesion (HSIL) cytology. METHODS:In this retrospective cohort study, women treated with a see-and...

journal_title：Journal of lower genital tract disease

authors： Smith HJ,Leath CA 3rd,Huh WK,Erickson BK

更新日期：2016-07-01 00:00:00

abstract：OBJECTIVE:This study aimed to determine whether electronic medical record (EMR)-based tools influence providers' compliance with guidelines for cervical cancer screening in adolescent (<21 y) patients. MATERIALS AND METHODS:Three EMR-based tools to educate providers on cervical cancer screening guidelines were impleme...

journal_title：Journal of lower genital tract disease

authors： White P,Kenton K

更新日期：2013-04-01 00:00:00

abstract：OBJECTIVE:In this study, we investigated whether physical inactivity was associated with risk of cervical cancer in women treated at an American cancer hospital. METHODS:This case-control study included 128 patients with cervical cancer and 512 controls matched on age. Controls were women suspected of having but not u...

journal_title：Journal of lower genital tract disease

authors： Szender JB,Cannioto R,Gulati NR,Schmitt KL,Friel G,Minlikeeva A,Platek A,Gower EH,Nagy R,Khachatryan E,Mayor PC,Kasza KA,Lele SB,Odunsi K,Moysich KB

更新日期：2016-07-01 00:00:00

abstract：:Atypical polypoid adenomyoma (APA) of the uterus is a rare, benign lesion. Histologically, it is composed of a glandular and squamous cell proliferation with architectural complexity and cytologic atypia of glands, and a hypercellular smooth muscle stroma. APA is difficult to distinguish from well-differentiated adeno...

journal_title：Journal of lower genital tract disease

authors： Jakus S,Edmonds P,Dunton C,Holland G

更新日期：2002-01-01 00:00:00

abstract：OBJECTIVE:The aims of the study were to define the heterogeneity of vulvodynia by determining data-driven subgroups within the vulvodynia diagnosis using exploratory cluster analysis and to characterize the subgroups identified. MATERIALS AND METHODS:Included were participants in the longitudinal population-based stud...

journal_title：Journal of lower genital tract disease

authors： Reed BD,Plegue MA,Williams DA,Sen A

更新日期：2016-01-01 00:00:00

abstract：OBJECTIVES:To determine whether Hybrid Capture 2 High-Risk HPV DNA Test (HC2) can be used as a test of cure in women treated for cervical intraepithelial neoplasia grade 2 or worse (CIN 2+) and allow discharge from colposcopy follow-up with a return to a cytology-based screening program for HC2-negative women. MATERIA...

journal_title：Journal of lower genital tract disease

authors： Ceballos KM,Lee M,Cook DA,Smith LW,Gondara L,Krajden M,van Niekerk DJ,Coldman AJ

更新日期：2017-10-01 00:00:00

abstract：OBJECTIVE:This study aimed to conduct a representative survey of human papillomavirus (HPV) prevalence and its genotype distribution in invasive anal cancer specimens in the United States. MATERIALS AND METHODS:Population-based archival anal cancer specimens were identified from Florida, Kentucky, Louisiana, and Michi...

journal_title：Journal of lower genital tract disease

authors： Steinau M,Unger ER,Hernandez BY,Goodman MT,Copeland G,Hopenhayn C,Cozen W,Saber MS,Huang Y,Peters ES,Lynch CF,Wilkinson EJ,Rajeevan MS,Lyu C,Saraiya M

更新日期：2013-10-01 00:00:00

abstract：OBJECTIVE:Determine the extent of endocervical canal extension of the transformation zone on fresh hysterectomy specimens. MATERIALS AND METHODS:After removal for standard gynecologic indications, 201 uteri were evaluated in the pathology accessioning area of a community hospital before formalin fixation. Uteri were o...

journal_title：Journal of lower genital tract disease

authors： Parker MF,O'Connor DM

更新日期：2003-10-01 00:00:00

abstract：OBJECTIVE:We evaluated the performance of the Papanicolaou smear in screening and diagnostic settings. STUDY DESIGN:We analyzed Papanicolaou smear results of 1,850 women recruited into a clinical trial to evaluate an emerging technology for the detection of cervical cancer. Screening and diagnosis groups were based on...

journal_title：Journal of lower genital tract disease

authors： Cárdenas-Turanzas M,Follen M,Nogueras-Gonzalez GM,Benedet JL,Beck JR,Cantor SB

更新日期：2008-10-01 00:00:00

abstract：OBJECTIVE:The natural evolution of atypical glandular cells of undetermined significance (AGUS) within a dysplasia clinic population has not yet been studied. The purpose of this study was to determine the outcome of cervico-vaginal smears with the diagnosis of AGUS from dysplasia clinic patients. MATERIAL AND METHODS...

journal_title：Journal of lower genital tract disease

authors： Parai JL,Yazdi HM,Faught JW

更新日期：1998-10-01 00:00:00

abstract：:Disseminated tuberculosis involving the uterine cervix and central nervous system is described in a 26-year-old Native American female with new-onset seizures. Her presenting complaint was generalized seizures with associated weight loss, chronic cough, global headache, and malaise. Pelvic examination revealed an exop...

journal_title：Journal of lower genital tract disease

authors： Kern TW,Waxman AG,Kilgo R,Tempest B

更新日期：1999-04-01 00:00:00

abstract：:OBJECTIVES.: This study evaluates the long-term clinical success of Durasphere (Carbon Metal Technologies, St. Paul, MN) compared with Contigen (C. R. Bard, Covington, GA) in the treatment of stress urinary incontinence caused by intrinsic sphincter deficiency (ISD). METHODS.: Fifty-two women diagnosed with stress uri...

journal_title：Journal of lower genital tract disease

authors： Andersen RC

更新日期：2002-10-01 00:00:00

abstract：OBJECTIVE:To relate aspects of online colposcopic image assessment to the diagnosis of grades 2 and 3 cervical intraepithelial neoplasia (CIN 2+). METHODS:To simulate colposcopic assessment, we obtained digitized cervical images at enrollment after acetic acid application from 919 women referred for equivocal or minor...

journal_title：Journal of lower genital tract disease

authors： Massad LS,Jeronimo J,Katki HA,Schiffman M,National Institutes of Health\/American Society for Colposcopy and Cervical Pathology Research Group.

更新日期：2009-07-01 00:00:00

abstract：OBJECTIVE:The Home Study Course is intended for the practicing colposcopist or practitioner who is seeking to develop or enhance his or her colposcopic skills. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management, or that demonstrate ...

journal_title：Journal of lower genital tract disease

authors： Berry JM,Darragh TM

更新日期：2005-07-01 00:00:00

abstract：OBJECTIVE:Obese women have higher cervical cancer incidence and mortality than their counterparts, possibly related to nonadherence to screening recommendations. We assessed the association of body mass index with adherence to cervical cancer screening recommendations in Hispanic women living in Puerto Rico, a minority...

journal_title：Journal of lower genital tract disease

authors： Pérez CM,González-Barrios D,Ramos-Cartagena JM,Ortiz AP

更新日期：2020-01-01 00:00:00

abstract：OBJECTIVE:This study aimed to highlight that colposcopic vaginal patterns are not specific, unlike cervical colposcopic patterns, and to provide a simpler classification of vaginal colposcopic patterns. MATERIALS AND METHODS:A total of 223 patients who underwent colposcopy with Schiller test were assessed (hierarchica...

journal_title：Journal of lower genital tract disease

authors： Indraccolo U,Baldoni A

更新日期：2012-04-01 00:00:00

abstract：:This review highlights recent advances in our understanding of preneoplastic squamous lesions of the vulva, from a pathologist's perspective. Vulvar intraepithelial neoplasia (VIN) is the preferred nomenclature for these lesions. VIN lesions may or may not be symptomatic and have a variable clinical appearance. Three ...

journal_title：Journal of lower genital tract disease

authors： Colgan TJ

更新日期：1998-01-01 00:00:00

abstract：OBJECTIVE:This study aimed to compare digital camera assessment of the reproductive tract (DART) to colposcopy for the evaluation of abnormal Pap smears. MATERIALS AND METHODS:Participants included 207 women with abnormal Pap smears. Colposcopy and DART were performed on each patient by separate examiners with the goa...

journal_title：Journal of lower genital tract disease

authors： Cremer ML,Peralta EI,Dheming SG,Jimenez ME,Davis-Dao CA,Alonzo TA,Blumenthal PD,Felix JC

更新日期：2010-01-01 00:00:00

abstract：OBJECTIVE:To study the clinicopathologic features of a rare disease of pagetoid urothelial intraepithelial neoplasia (PUIN) in the vulva. MATERIALS AND METHODS:We reviewed a case of PUIN in a Chinese woman with a long history of bladder urothelial carcinoma. RESULTS:The patient presented with vulvar pruritus for more...

journal_title：Journal of lower genital tract disease

authors： Lu B,Liang Y

更新日期：2015-01-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to assess whether lower proportions of cervical intraepithelial neoplasia 2+ diagnosed by random biopsy are from lower cut points defining an abnormal colposcopic impression or obtaining only one random biopsy when colposcopic impression is normal. METHODS:We compared colposcopy expe...

journal_title：Journal of lower genital tract disease

authors： Pretorius RG,Belinson JL,Burchette RJ,Wu R,Qiao YL

更新日期：2019-10-01 00:00:00

abstract：OBJECTIVE:The aim of the study was to evaluate the validity of anal cytology against high-resolution anoscopy in the detection of anal high-grade squamous intraepithelial lesions (HSILs) among women in a clinical setting in Puerto Rico, alone and in combination with high-risk human papillomavirus (HR-HPV) typing. MATE...

journal_title：Journal of lower genital tract disease

authors： Ramos-Cartagena JM,Pérez CM,Guiot HM,Amaya-Ardilla CP,Tirado-Gómez M,Ortiz AP

更新日期：2020-01-01 00:00:00

abstract：:We describe a rare case of clitoromegaly due to a large clitoral cyst that occurred spontaneously without any declared previous female genital mutilation. The cyst was excised successfully with good cosmetic results. ...

journal_title：Journal of lower genital tract disease

authors： Al-Ojaimi EH,Abdulla MM

更新日期：2013-01-01 00:00:00