Abstract:
BACKGROUND:The authors' objective was to determine retrospectively the methods used to follow up atypical glandular cells of undetermined significance (AGUS) on Papanicolaou smears and to evaluate the effectiveness of those methods. MATERIAL AND METHODS:The charts of all patients with AGUS smears obtained between February 1993 and April 1996 were reviewed retrospectively, and information was extracted. A computer database was used to identify the patients and review the method of evaluation. The findings from histological sampling also are reported and analyzed. All findings are reported descriptively. RESULTS:Seventy-nine AGUS smears were evaluated. Of these, it was found that six patients had no follow-up. Of the 62 with histological followup, most (74%) underwent colposcopy, endometrial biopsy (63%), or endocervical curettage (50%). Cervical or vaginal biopsy, cervical conization, hysteroscopy, and hysterectomy also were performed. Twenty-seven patients underwent more than one procedure for tissue sampling. Of the 62 patients from whom histological samples were taken, 18 (29%) were found to have clinically significant lesions, 11 of which were carcinomas. CONCLUSIONS:In our clinic, AGUS smears are a result of a significant number of high-grade neoplastic findings. Histological evaluation is necessary in most cases for accurate diagnosis because of the multiple, varied potential etiologies of AGUS smears.
journal_name
J Low Genit Tract Disjournal_title
Journal of lower genital tract diseaseauthors
Landry MS,Julian TMdoi
10.1097/00128360-199704000-00007subject
Has Abstractpub_date
1997-04-01 00:00:00pages
78-81issue
2eissn
1089-2591issn
1526-0976pii
00128360-199704000-00007journal_volume
1pub_type
杂志文章abstract::OBJECTIVES.: To determine the prevalence of cervical dysplasia, diagnosed cytologically (squamous intraepithelial lesion [SIL]) or histologically (cervical intraepithelial neoplasia [CIN]), in women with external anogenital warts, and to determine the discriminating risk factors between those with and without cervical...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200301000-00006
更新日期:2003-01-01 00:00:00
abstract:OBJECTIVE:This study aimed to report 2 cases of squamous cell carcinoma (SCC) of the vulva, arising from unusual subepithelial locations. MATERIALS AND METHODS:The first case was of an 85-year-old woman with a 65-year history of a mass in the left labium majus. The second case was of a 54-year-old woman who presented ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31827a8c95
更新日期:2013-10-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to describe temporal trends in screening and outcomes for women, after changes in guidelines in Alberta, Canada, that raised starting age to 21 years, then to 25 years of age, and reduced frequency to 3 yearly. MATERIALS AND METHODS:Calgary Laboratory Information System data were use...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000574
更新日期:2021-01-01 00:00:00
abstract:OBJECTIVE:The Home Study Course is intended for the practicing colposcopist or practitioner who is seeking to develop or enhance his or her colposcopic skills. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management, or that demonstrate ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/01.lgt.0000171660.77437.f2
更新日期:2005-07-01 00:00:00
abstract:OBJECTIVE:To determine if sites selected for colposcopic biopsy and histologically proven cervical intraepithelial neoplasia are distributed randomly across the cervix. MATERIALS AND METHODS:Data were evaluated from all patients who visited the Walter Reed Army Medical Center Colposcopy Clinic during a 20-month period...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200501000-00008
更新日期:2005-01-01 00:00:00
abstract:PURPOSE:To compare the collection of vaginal exudates with and without the use of a speculum to diagnose vaginal infections. MATERIAL AND METHODS:We examined 45 patients with vaginal discharge. Two vaginal swabs were taken, one with and the other without a speculum. Both were examined by wet mount microscopy to detect...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/01.lgt.0000179859.29456.ba
更新日期:2005-10-01 00:00:00
abstract:OBJECTIVE:In women with negative cervical cytology and positive high-risk human papillomavirus (HR-HPV) test results, we compared the risk of cervical intraepithelial neoplasia 3 (CIN 3) or cancer (CIN 3+) in women with previous abnormal cervical cytology, CIN, or HR-HPV with that in women without this history, and we ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e318281f182
更新日期:2013-10-01 00:00:00
abstract:BACKGROUND:Basal cell carcinoma (BCC) is a rare tumor of the vulva; it accounts for approximately 2% to 4% of vulvar cancer. CASE:A 73-year-old woman was referred because of a 2-cm ulcerative lesion on her perineum, near the anus. Punch biopsy showed BCC. She underwent wide local excision of tumor without any damage t...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/01.lgt.0000225898.37090.04
更新日期:2006-10-01 00:00:00
abstract:OBJECTIVE:Visual assessment of digitized cervigrams through the Internet needs to be optimized. The National Cancer Institute and National Library of Medicine are involved in a large effort to improve colposcopic assessment and, in preparation, are conducting methodologic research. MATERIALS AND METHODS:We selected 50...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/01.lgt.0000192696.93172.ae
更新日期:2006-01-01 00:00:00
abstract:OBJECTIVE:The natural evolution of atypical glandular cells of undetermined significance (AGUS) within a dysplasia clinic population has not yet been studied. The purpose of this study was to determine the outcome of cervico-vaginal smears with the diagnosis of AGUS from dysplasia clinic patients. MATERIAL AND METHODS...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-199810000-00001
更新日期:1998-10-01 00:00:00
abstract:OBJECTIVE:Cervical cancer is one of the most common malignancies in pregnancy and one percent of women diagnosed with cervical cancer are pregnant or postpartum at the time of the diagnosis. We discuss how pregnancy will affect the management of cancer, and cancer will affect the management of the pregnancy. MATERIAL ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31824d6fb8
更新日期:2013-01-01 00:00:00
abstract:OBJECTIVE:The study aimed to identify sociodemographic and disease-specific factors associated with follow-up in an inner-city multiethnic colposcopy clinic. MATERIALS AND METHODS:All charts of patients referred to colposcopy clinic for abnormal cervical cytology and/or high-risk human papillomavirus infections to the...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e318249640f
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:To compare the results of cold knife conization (CKC) and loop electrosurgical excision procedure (LEEP) for cervical intraepithelial neoplasia to determine if excisional method has effects on pathologic interpretation. METHODS:Retrospective review of the perioperative medical records of patients who had a C...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31817ff940
更新日期:2009-01-01 00:00:00
abstract:OBJECTIVES:To evaluate the therapeutic efficacy and adverse events of electrofulguration for the treatment of cervical intraepithelial lesion grade 1 (CIN 1). MATERIALS AND METHODS:Women aged 19 years and older received electrofulguration for histologically proven exocervical CIN 1. They were followed up at 3, 6, and ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200401000-00004
更新日期:2004-01-01 00:00:00
abstract:OBJECTIVE:The aim of the study was to compare the effectiveness of mindfulness-based group cognitive behavior therapy (M-gCBT) versus education support group therapy for the pain and distress associated with provoked localized vulvodynia. MATERIALS AND METHODS:Participants were randomized to M-gCBT or education suppor...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,随机对照试验
doi:10.1097/LGT.0000000000000456
更新日期:2019-04-01 00:00:00
abstract:OBJECTIVE:This study aimed to provide information about the molecular epidemiology of human papillomavirus (HPV) in a group of Cuban women. MATERIALS AND METHODS:DNA from cervical samples was analyzed using a quantitative real-time polymerase chain reaction (PCR), which detects 6 of the clinically most relevant high-r...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e3182a7bb89
更新日期:2014-07-01 00:00:00
abstract::A 26-year-old patient with a history of chemotherapy for acute lymphoblastic leukemia presented with secondary amenorrhea and cyclic abdominal pain, and she was found to have vaginal stenosis due to adhesion of vaginal wall. The cause of the adhesion was considered to be vaginal inflammation induced by anticancer agen...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000175
更新日期:2016-04-01 00:00:00
abstract::A 17-year-old adolescent girl developed severe toxic epidermal necrolysis after inhalation of methamphetamine. Recovery was complicated by vaginal synechiae and occlusion necessitating surgery. ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e3181ddf5da
更新日期:2010-10-01 00:00:00
abstract:OBJECTIVE:To estimate the frequency of abnormal Pap and human papillomavirus (HPV) positivity among human immunodeficiency virus (HIV)-seropositive and -seronegative women who have sex with women (WSW). METHODS:Pap and HPV DNA polymerase chain reaction tests were obtained every 6 months from women in a US cohort of HI...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,多中心研究
doi:10.1097/LGT.0b013e3182942733
更新日期:2014-01-01 00:00:00
abstract:OBJECTIVE:Metronidazole vaginal gel (MVG) 0.75% is a US Food and Drug Administration-approved, 5-day treatment for bacterial vaginosis (BV). This study tested the hypothesis that a shorter treatment course at a higher dose (MVG 1.3%) would yield similar efficacy to 5 days of MVG 0.75%. MATERIALS AND METHODS:This phase...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,多中心研究,随机对照试验
doi:10.1097/LGT.0000000000000062
更新日期:2015-04-01 00:00:00
abstract:OBJECTIVE:To measure the recurrence rate of disease in women treated for cervical adenocarcinoma in situ (ACIS) by either hysterectomy or conservative surgical management. PATIENTS AND METHODS:One hundred patients with a histopathologic diagnosis of ACIS or glandular dysplasia were identified in a retrospective clinic...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/00128360-200404000-00008
更新日期:2004-04-01 00:00:00
abstract:BACKGROUND:: Lack of estrogen after menopause can cause many changes in the lower genital tract of women, including involution of the introitus and collapse of the vestibule into the genital cleft. CASES:: Six cases of hypoestrogenic women are described, with the unusual finding of entrapment of terminal hairs between...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e31821a68a5
更新日期:2011-10-01 00:00:00
abstract:OBJECTIVE:The aims of the study were to define the heterogeneity of vulvodynia by determining data-driven subgroups within the vulvodynia diagnosis using exploratory cluster analysis and to characterize the subgroups identified. MATERIALS AND METHODS:Included were participants in the longitudinal population-based stud...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000166
更新日期:2016-01-01 00:00:00
abstract:OBJECTIVE:We evaluated the performance of the Papanicolaou smear in screening and diagnostic settings. STUDY DESIGN:We analyzed Papanicolaou smear results of 1,850 women recruited into a clinical trial to evaluate an emerging technology for the detection of cervical cancer. Screening and diagnosis groups were based on...
journal_title:Journal of lower genital tract disease
pub_type: 临床试验,杂志文章,多中心研究
doi:10.1097/LGT.0b013e31816b44bc
更新日期:2008-10-01 00:00:00
abstract:OBJECTIVES OF THE STUDY:To systematically evaluate the literature regarding vulvodynia treatment outcome measures. METHODS:A systematic literature search on OVID, PubMed, and PsycINFO databases was conducted from inception until May 2016. Studies were included/excluded based on prespecified criteria. Reported outcome ...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,评审
doi:10.1097/LGT.0000000000000406
更新日期:2018-07-01 00:00:00
abstract:OBJECTIVE:Bacterial vaginosis (BV) is a common cause of genital discomfort in women in reproductive ages, which causes many complications. Bacterial vaginosis is usually treated by metronidazole and clindamycin. However, this protocol does not prevent its recurrence, which is a main complaint of the patients. The numbe...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,评审
doi:10.1097/LGT.0b013e31829156ec
更新日期:2014-01-01 00:00:00
abstract:UNLABELLED:OBIECTIVE: This study aimed to evaluate the safety of conservative treatment in women desiring preservation of fertility with stage IA adenocarcinoma of the cervix. MATERIALS AND METHODS:Clinical report of all women with stage IA adenocarcinoma of the cervix, endocervical subtype, with clear margins on cone...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0b013e3182446b3a
更新日期:2012-10-01 00:00:00
abstract:OBJECTIVE:The Home Study Course is intended for the practicing colposcopist or practitioner who is seeking to develop or enhance his/her colposcopic skills. The goal of the course is to present colposcopic cases that are unusual or instructive in terms of appearance, presentation, or management, or that demonstrate new...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/lgt.0b013e3180380fd3
更新日期:2007-04-01 00:00:00
abstract:OBJECTIVE:Large loop excision of the transformation zone (LLETZ) is the standard surgical treatment for cervical dysplasia. The optimal way to achieve local hemostasis in women undergoing LLETZ is unknown. MATERIALS AND METHODS:In a prospective, randomized trial, we compared spray coagulation and forced coagulation in...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章,随机对照试验
doi:10.1097/LGT.0000000000000177
更新日期:2016-04-01 00:00:00
abstract:OBJECTIVE:The study aims to assess the frequency of cytological abnormalities in adolescents and young women, to establish the optimum age to start screening. METHODS:A retrospective study of cervical cytology results were obtained from the data center at the Santa Casa Hospital of São Paulo between January 2006 and D...
journal_title:Journal of lower genital tract disease
pub_type: 杂志文章
doi:10.1097/LGT.0000000000000273
更新日期:2017-01-01 00:00:00