The developmental origin of cervical and vaginal epithelium and their clinical consequences: a systematic review.

Abstract:

OBJECTIVE:Studies on the development of the embryological and fetal development of the cervix and the vagina are rare and mostly go back to the first decades of the last century. The aims of this review were to present the latest knowledge concerning the developmental origin of cervical and vaginal epithelium and to point out new results in the context of different clinical findings. MATERIALS AND METHODS:Relevant studies published between 1910 and 2013 were identified via PubMed, MEDLINE, OVID, Web of Science, and EMBASE. The reference lists of retrieved articles were reviewed to locate additional articles. Each abstract was reviewed, and the appropriate publications were obtained and reviewed as well. A total of 33 articles and 8 book chapters were selected for citation in this review. RESULTS:New objective findings clearly show that human prenatal epithelialization of the cervix and vagina results in 3 morphogenetically determined units: (i) the Müllerian columnar epithelium of the endocervix, (ii) the Müllerian squamous epithelium of the ectocervix and the upper vagina, and (iii) the vaginal squamous epithelium of the lower vagina. CONCLUSIONS:These results are of high clinical relevance and may provide new insight into the histogenesis of ectopy, vaginal adenosis, and the congenital transformation zone. They should be added to the explanations in gynecological, colposcopical, and gynecopathological textbooks.

journal_name

J Low Genit Tract Dis

authors

Reich O,Fritsch H

doi

10.1097/LGT.0000000000000023

subject

Has Abstract

pub_date

2014-10-01 00:00:00

pages

358-60

issue

4

eissn

1089-2591

issn

1526-0976

journal_volume

18

pub_type

杂志文章,评审
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    abstract:OBJECTIVE:Bacterial vaginosis (BV) is a common cause of genital discomfort in women in reproductive ages, which causes many complications. Bacterial vaginosis is usually treated by metronidazole and clindamycin. However, this protocol does not prevent its recurrence, which is a main complaint of the patients. The numbe...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章,评审

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    更新日期:2014-01-01 00:00:00

  • Lesions and Neoplasms of the Penis: A Review.

    abstract::In addition to practitioners who care for male patients, with the increased use of high-resolution anoscopy, practitioners who care for women are seeing more men in their practices as well. Some diseases affecting the penis can impact on their sexual partners. Many of the lesions and neoplasms of the penis occur on th...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章,评审

    doi:10.1097/LGT.0000000000000159

    authors: Heller DS

    更新日期:2016-01-01 00:00:00

  • Long-term follow-up comparison of durasphere and contigen in the treatment of stress urinary incontinence.

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    doi:10.1097/00128360-200210000-00009

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  • Non-albicans Candida Vulvovaginitis: Treatment Experience at a Tertiary Care Vaginitis Center.

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    doi:10.1097/LGT.0000000000000126

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  • Chronic granulomatous inflammation of the vulva: an unusual presentation with diagnostic and therapeutic difficulties.

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    pub_type: 杂志文章

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    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000043

    authors: Dixit S,Selva-Nayagam P,Hamann I,Fischer G

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  • A case report of disseminated tuberculosis: an unsuspected uterine cervical mass in a young native american woman with new-onset seizure disorder.

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    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

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  • A Randomized Trial of Human Papillomavirus Self-Sampling as an Intervention to Promote Cervical Cancer Screening Among Women With HIV.

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    pub_type: 杂志文章,随机对照试验

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    doi:10.1097/LGT.0000000000000011

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    doi:10.1097/LGT.0b013e3181ed3d6d

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    pub_type: 杂志文章

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    journal_title:Journal of lower genital tract disease

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    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

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    pub_type: 杂志文章,评审

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    journal_title:Journal of lower genital tract disease

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    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000092

    authors: Lima-Silva J,Vieira-Baptista P,Cavaco-Gomes J,Maia T,Beires J

    更新日期:2015-04-01 00:00:00

  • Contribution of Exocervical Biopsy, Endocervical Curettage, and Colposcopic Grading in Diagnosing High-Grade Cervical Intraepithelial Neoplasia.

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