Preparing digitized cervigrams for colposcopy research and education: determination of optimal resolution and compression parameters.

Abstract:

OBJECTIVE:Visual assessment of digitized cervigrams through the Internet needs to be optimized. The National Cancer Institute and National Library of Medicine are involved in a large effort to improve colposcopic assessment and, in preparation, are conducting methodologic research. MATERIALS AND METHODS:We selected 50 cervigrams with diagnoses ranging from normal to cervical intraepithelial neoplasia 3 or invasive cancer. Those pictures were scanned at 5 resolution levels from 1,550 to 4,000 dots per inch (dpi) and were presented to 4 expert colposcopists to assess image quality. After the ideal resolution level was determined, pictures were compressed at 7 compression ratios from 20:1 to 80:1 to determine the optimal level of compression that permitted full assessment of key visual details. RESULTS:There were no statistically significant differences between the 3,000 and 4,000 dpi pictures. At 2,000 dpi resolution, only one colposcopist found a slightly statistically significant difference (p = 0.02) compared with the gold standard. There was a clear loss of quality of the pictures at 1,660 dpi. At compression ratio 60:1, 3 of 4 evaluators found statistically significant differences when comparing against the gold standard. CONCLUSIONS:Our results suggest that 2,000 dpi is the optimal level for digitizing cervigrams, and the optimal compression ratio is 50:1 using a novel wavelet-based technology. At these parameters, pictures have no significant differences with the gold standard.

journal_name

J Low Genit Tract Dis

authors

Jeronimo J,Long R,Neve L,Ferris D,Noller K,Spitzer M,Mitra S,Guo J,Nutter B,Castle P,Herrero R,Rodriguez AC,Schiffman M

doi

10.1097/01.lgt.0000192696.93172.ae

subject

Has Abstract

pub_date

2006-01-01 00:00:00

pages

39-44

issue

1

eissn

1089-2591

issn

1526-0976

pii

00128360-200601000-00007

journal_volume

10

pub_type

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