Electrofulguration for low-grade squamous intraepithelial lesions of the cervix (CIN 1).

Abstract:

OBJECTIVES:To evaluate the therapeutic efficacy and adverse events of electrofulguration for the treatment of cervical intraepithelial lesion grade 1 (CIN 1). MATERIALS AND METHODS:Women aged 19 years and older received electrofulguration for histologically proven exocervical CIN 1. They were followed up at 3, 6, and 12 months with cytologic analysis, colposcopy, and, when indicated, histologic examination. Therapeutic success was defined as absence of disease at 12 months after therapy. Adverse effects were recorded during and after the procedure. RESULTS:Of 78 women treated, 32 (41.0%) were lost to follow-up and 6 patients (7.7%) were retreated. Using intent-to-treat definition including patients lost to follow-up, 40 of 78 (52.6%) were free of disease at the 1-year follow-up visit. Excluding patients lost to follow-up, cure rates were 87% (40/46) and 100% (40/40) after single and repeat treatment, respectively. Adverse effects included mild to moderate discomfort (78%), intermittent spotting (70%), and pelvic pain (44%). The procedure lasted 2 minutes in 83% of cases and was easy to perform. CONCLUSIONS:Electrofulguration under local anesthesia is an attractive ablative treatment method for exocervical CIN 1 and compares favorably with cryocoagulation as per review of the literature.

journal_name

J Low Genit Tract Dis

authors

Roy MC,Mayrand MH,Franco E,Arseneau J,Ferenczy A

doi

10.1097/00128360-200401000-00004

subject

Has Abstract

pub_date

2004-01-01 00:00:00

pages

10-5

issue

1

eissn

1089-2591

issn

1526-0976

pii

00128360-200401000-00004

journal_volume

8

pub_type

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