Is colposcopy warranted in women with external anogenital warts?

Abstract:

:OBJECTIVES.: To determine the prevalence of cervical dysplasia, diagnosed cytologically (squamous intraepithelial lesion [SIL]) or histologically (cervical intraepithelial neoplasia [CIN]), in women with external anogenital warts, and to determine the discriminating risk factors between those with and without cervical dysplasia. MATERIALS AND METHODS.: Chart review of women referred to colposcopy for external anogenital warts from 1990 to 1999. Human papillomavirus risk factors predictive for cervical dysplasia were assessed by logistic and Cox regression models. RESULTS.: There were 496 patients in this study. The prevalence of SIL by cytology was 20%: 18% low-grade squamous intraepithelial lesion and 2% high-grade squamous intraepithelial lesion. The combination of Pap smear and colposcopically directed biopsy identified dysplasia (SIL or CIN) in 30%, 4% of which were high-risk lesions (high-grade squamous intraepithelial lesion or CIN 2,3). Colposcopy performed much better than the Pap test alone in detecting CIN 2,3 lesions; 16 of 18 cases of CIN 2,3 diagnosed on biopsy had Pap smear results of low-grade squamous intraepithelial lesion or less, 7 of which were normal. Two thirds of those diagnosed with CIN 2,3 were aged 25 years and older. No differences in human papillomavirus infection risk factors were found between women with and without cervical dysplasia. CONCLUSIONS.: The high prevalence of CIN 2,3 in women with external anogenital warts warrants evaluation with colposcopy, particularly in women aged 25 years and older.

journal_name

J Low Genit Tract Dis

authors

Li J,Rousseau MC,Franco EL,Ferenczy A

doi

10.1097/00128360-200301000-00006

subject

Has Abstract

pub_date

2003-01-01 00:00:00

pages

22-8

issue

1

eissn

1089-2591

issn

1526-0976

pii

00128360-200301000-00006

journal_volume

7

pub_type

杂志文章
  • Fabric-based exocervical and endocervical biopsy in comparison with punch biopsy and sharp curettage.

    abstract:OBJECTIVES:Fabric-based endocervical and exocervical biopsy tools were compared with exocervical punch biopsy and sharp endocervical curettage. We compared the level of pain reported by the patient and the amount of bleeding rated by the physician relative to the type of biopsy used. MATERIALS AND METHODS:This was a 2...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章,随机对照试验

    doi:10.1097/LGT.0b013e318234262d

    authors: Winter M,Cestero RM,Burg A,Felix JC,Han C,Raffo AM,Vasilev S

    更新日期:2012-04-01 00:00:00

  • Localized Provoked Vulvodynia: Association With Nerve Growth Factor and Transient Receptor Potential Vanilloid Type 1 Genes Polymorphisms.

    abstract:OBJECTIVE:The aim of the study was to study the associations between localized provoked vulvodynia (LPV) and several single-nucleotide polymorphisms (SNPs) in the transient receptor potential vanilloid type 1 (TRPV1), nerve growth factor (NGF), and the heparanase (HPSE) genes. MATERIALS AND METHODS:Prevalence of SNPs ...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000445

    authors: Kalfon L,Azran A,Farajun Y,Golan-Hamu O,Toben A,Abramov L,Yeshaya A,Yakir O,Zarfati D,Falik Zaccai TC,Bornstein J

    更新日期:2019-01-01 00:00:00

  • High Rates of High-Grade Cervical Dysplasia in High-Risk Young Women With Low-Grade Cervical Cytology.

    abstract:OBJECTIVE:The aim of the study was to determine rates of cervical intraepithelial neoplasia (CIN) 2 or greater in high-risk, racially diverse, young women with low-grade cytology. MATERIALS AND METHODS:After institutional review board approval, a cross-sectional study of 21- to 24-year-old women with low-grade cytolog...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000381

    authors: Daily LR,Erickson BK,Pasko DN,Straughn JM Jr,Huh WK,Leath CA 3rd

    更新日期:2018-07-01 00:00:00

  • Pagetoid spread of bladder urothelial carcinoma to the vagina and vulva.

    abstract:OBJECTIVE:To study the clinicopathologic features of a rare disease of pagetoid urothelial intraepithelial neoplasia (PUIN) in the vulva. MATERIALS AND METHODS:We reviewed a case of PUIN in a Chinese woman with a long history of bladder urothelial carcinoma. RESULTS:The patient presented with vulvar pruritus for more...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000020

    authors: Lu B,Liang Y

    更新日期:2015-01-01 00:00:00

  • A Systematic Review of Tests for Postcolposcopy and Posttreatment Surveillance.

    abstract:OBJECTIVE:For the 2019 ASCCP Risk-Based Management Consensus Guidelines, we conducted a systematic review of diagnostic assays for postcolposcopy and posttreatment management. MATERIALS AND METHODS:A literature search was conducted to identify articles reporting on tests/assays for cervical cancer screening, triage, p...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章,meta分析

    doi:10.1097/LGT.0000000000000526

    authors: Clarke MA,Unger ER,Zuna R,Nelson E,Darragh TM,Cremer M,Stockdale CK,Einstein MH,Wentzensen N

    更新日期:2020-04-01 00:00:00

  • Biopsy site selection during colposcopy and distribution of cervical intraepithelial neoplasia.

    abstract:OBJECTIVE:To determine if sites selected for colposcopic biopsy and histologically proven cervical intraepithelial neoplasia are distributed randomly across the cervix. MATERIALS AND METHODS:Data were evaluated from all patients who visited the Walter Reed Army Medical Center Colposcopy Clinic during a 20-month period...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/00128360-200501000-00008

    authors: Allard JE,Rodriguez M,Rocca M,Parker MF

    更新日期:2005-01-01 00:00:00

  • Comparison of Tissue Yield Using Frictional Fabric Brush Versus Sharp Curettage For Endocervical Curettage.

    abstract:OBJECTIVE:The aim of the study was to evaluate and compare the diagnostic yield of conventional endocervical curettage (ECC) with fabric-based ECC in a consistent physician group. MATERIALS AND METHODS:This is a retrospective case-control study of patients who underwent ECC both before and after introduction of a fabr...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000324

    authors: Diedrich JT,Rathore S,Bentz JS

    更新日期:2017-10-01 00:00:00

  • Expression of p16INK4 and Rb Genes in Cervical Neoplasm.

    abstract:BACKGROUND:The molecular events surrounding the pathogenesis of human cervical cancer remain to be defined to a significant extent. The current study investigates the expression of two putative tumor suppressor genes p16 and Rb in cervical neoplasm. MATERIALS AND METHODS:Tissue was collected from 16 cervical intraepit...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/00128360-199710000-00008

    authors: Wong YF,Cheung TH,Chung TK,Chan MK,Chang AM

    更新日期:1997-10-01 00:00:00

  • Contribution of Exocervical Biopsy, Endocervical Curettage, and Colposcopic Grading in Diagnosing High-Grade Cervical Intraepithelial Neoplasia.

    abstract:OBJECTIVE:To determine the utility of random biopsy and endocervical curettage (ECC) during colposcopy among women who ultimately underwent cervical excisional biopsy. MATERIALS AND METHODS:In a retrospective observational study, the charts were reviewed of every patient who underwent cervical excisional procedure per...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e3182a5296e

    authors: Diedrich JT,Felix JC,Lonky NM

    更新日期:2016-01-01 00:00:00

  • Cost-effectiveness of adding human papilloma virus testing to a managed care cervical cancer screening program.

    abstract:OBJECTIVE:The purpose of this study was to demonstrate a methodology for auditing the impact of HCII testing on the direct cost of cervical cancer cytological screening, where the test is collected in all women screened and processed routinely in women age 30 years and older. MATERIALS AND METHODS:After a policy chang...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e318057f319

    authors: Lonky NM,Hunter MI,Sadeghi M,Edwards G,Bajamundi K,Monk BJ

    更新日期:2007-10-01 00:00:00

  • Digital assessment of the reproductive tract versus colposcopy for directing biopsies in women with abnormal Pap smears.

    abstract:OBJECTIVE:This study aimed to compare digital camera assessment of the reproductive tract (DART) to colposcopy for the evaluation of abnormal Pap smears. MATERIALS AND METHODS:Participants included 207 women with abnormal Pap smears. Colposcopy and DART were performed on each patient by separate examiners with the goa...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e3181a02058

    authors: Cremer ML,Peralta EI,Dheming SG,Jimenez ME,Davis-Dao CA,Alonzo TA,Blumenthal PD,Felix JC

    更新日期:2010-01-01 00:00:00

  • Collagen expression in the pregnant human cervix is decreased with labor.

    abstract:OBJECTIVE:The current study tested the hypothesis that collagen content in the pregnant cervix decreases with labor, using morphologically preserved specimens, avoiding limitations of earlier studies. Collagen abundance remote from pregnancy was also evaluated. MATERIALS AND METHODS:Histologic sections of postpartum c...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e31822bb004

    authors: Heller DS,Goldsmith LT,Aboujaoude R,Kaplan C,Baergen R,Cole D

    更新日期:2012-01-01 00:00:00

  • Cervical cancer in pregnancy: 3 cases, 3 different approaches.

    abstract:OBJECTIVE:Cervical cancer is one of the most common malignancies in pregnancy and one percent of women diagnosed with cervical cancer are pregnant or postpartum at the time of the diagnosis. We discuss how pregnancy will affect the management of cancer, and cancer will affect the management of the pregnancy. MATERIAL ...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e31824d6fb8

    authors: Ribeiro F,Correia L,Paula T,Santana I,Vieira Pinto L,Borrego J,Jorge AF

    更新日期:2013-01-01 00:00:00

  • Treatment of cervical intraepithelial neoplasia levels 2 and 3 with adapalene, a retinoid-related molecule.

    abstract:OBJECTIVES:This study examined dose scheduling, safety, and efficacy of adapalene in the treatment of CIN2 and CIN3. METHODS:Patients were instructed on insertion and removal of an adapalene delivery system. Treatment regimens of 4, 8, and 14 days were utilized. Biopsies were performed on day 90 to assess efficacy. Sa...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1046/j.1526-0976.2001.51007.x

    authors: DiSilvestro PA,DiSilvestro JM,Lernhardt W,Pfahl M,Mannel RS

    更新日期:2001-01-01 00:00:00

  • Conservative treatment of microinvasive adenocarcinoma of uterine cervix: long-term follow-up.

    abstract:UNLABELLED:OBIECTIVE: This study aimed to evaluate the safety of conservative treatment in women desiring preservation of fertility with stage IA adenocarcinoma of the cervix. MATERIALS AND METHODS:Clinical report of all women with stage IA adenocarcinoma of the cervix, endocervical subtype, with clear margins on cone...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e3182446b3a

    authors: Sopracordevole F,Canzonieri V,Giorda G,De Piero G,Lucia E,Campagnutta E

    更新日期:2012-10-01 00:00:00

  • Association of Body Mass Index With Adherence to Cervical Cancer Screening Recommendations in Hispanic Women.

    abstract:OBJECTIVE:Obese women have higher cervical cancer incidence and mortality than their counterparts, possibly related to nonadherence to screening recommendations. We assessed the association of body mass index with adherence to cervical cancer screening recommendations in Hispanic women living in Puerto Rico, a minority...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000504

    authors: Pérez CM,González-Barrios D,Ramos-Cartagena JM,Ortiz AP

    更新日期:2020-01-01 00:00:00

  • Impact of Physical Inactivity on Risk of Developing Cancer of the Uterine Cervix: A Case-Control Study.

    abstract:OBJECTIVE:In this study, we investigated whether physical inactivity was associated with risk of cervical cancer in women treated at an American cancer hospital. METHODS:This case-control study included 128 patients with cervical cancer and 512 controls matched on age. Controls were women suspected of having but not u...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000210

    authors: Szender JB,Cannioto R,Gulati NR,Schmitt KL,Friel G,Minlikeeva A,Platek A,Gower EH,Nagy R,Khachatryan E,Mayor PC,Kasza KA,Lele SB,Odunsi K,Moysich KB

    更新日期:2016-07-01 00:00:00

  • Key Determinants of the Value of Random Cervical Biopsy at Colposcopy.

    abstract:OBJECTIVE:The aim of the study was to assess whether lower proportions of cervical intraepithelial neoplasia 2+ diagnosed by random biopsy are from lower cut points defining an abnormal colposcopic impression or obtaining only one random biopsy when colposcopic impression is normal. METHODS:We compared colposcopy expe...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000485

    authors: Pretorius RG,Belinson JL,Burchette RJ,Wu R,Qiao YL

    更新日期:2019-10-01 00:00:00

  • The accuracy of the Papanicolaou smear in the screening and diagnostic settings.

    abstract:OBJECTIVE:We evaluated the performance of the Papanicolaou smear in screening and diagnostic settings. STUDY DESIGN:We analyzed Papanicolaou smear results of 1,850 women recruited into a clinical trial to evaluate an emerging technology for the detection of cervical cancer. Screening and diagnosis groups were based on...

    journal_title:Journal of lower genital tract disease

    pub_type: 临床试验,杂志文章,多中心研究

    doi:10.1097/LGT.0b013e31816b44bc

    authors: Cárdenas-Turanzas M,Follen M,Nogueras-Gonzalez GM,Benedet JL,Beck JR,Cantor SB

    更新日期:2008-10-01 00:00:00

  • Cervical Screening Practices and Outcomes for Young Women in Response to Changed Guidelines in Calgary, Canada, 2007-2016.

    abstract:OBJECTIVE:The aim of the study was to describe temporal trends in screening and outcomes for women, after changes in guidelines in Alberta, Canada, that raised starting age to 21 years, then to 25 years of age, and reduced frequency to 3 yearly. MATERIALS AND METHODS:Calgary Laboratory Information System data were use...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000574

    authors: Sayed SA,Naugler C,Chen G,Dickinson JA

    更新日期:2021-01-01 00:00:00

  • Clinical Characteristics and Treatment Response With Checkpoint Inhibitors in Malignant Melanoma of the Vulva and Vagina.

    abstract:OBJECTIVES:The aims of the study were to assess the clinical and histopathological characteristics of a comprehensive cohort of women with vulvovaginal melanoma (VVM) treated at our institution and to study the treatment response of checkpoint inhibitors in this patient cohort. MATERIALS AND METHODS:This is a retrospe...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000583

    authors: Wohlmuth C,Wohlmuth-Wieser I,Laframboise S

    更新日期:2020-11-24 00:00:00

  • Interpretability of excisional biopsies of the cervix: cone biopsy and loop excision.

    abstract:OBJECTIVE:To compare the results of cold knife conization (CKC) and loop electrosurgical excision procedure (LEEP) for cervical intraepithelial neoplasia to determine if excisional method has effects on pathologic interpretation. METHODS:Retrospective review of the perioperative medical records of patients who had a C...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e31817ff940

    authors: Miroshnichenko GG,Parva M,Holtz DO,Klemens JA,Dunton CJ

    更新日期:2009-01-01 00:00:00

  • Effects of probiotics on the recurrence of bacterial vaginosis: a review.

    abstract:OBJECTIVE:Bacterial vaginosis (BV) is a common cause of genital discomfort in women in reproductive ages, which causes many complications. Bacterial vaginosis is usually treated by metronidazole and clindamycin. However, this protocol does not prevent its recurrence, which is a main complaint of the patients. The numbe...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章,评审

    doi:10.1097/LGT.0b013e31829156ec

    authors: Homayouni A,Bastani P,Ziyadi S,Mohammad-Alizadeh-Charandabi S,Ghalibaf M,Mortazavian AM,Mehrabany EV

    更新日期:2014-01-01 00:00:00

  • Giant epidermoid inclusion cyst of the clitoris mimicking clitoromegaly.

    abstract::We describe a rare case of clitoromegaly due to a large clitoral cyst that occurred spontaneously without any declared previous female genital mutilation. The cyst was excised successfully with good cosmetic results. ...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e318259a410

    authors: Al-Ojaimi EH,Abdulla MM

    更新日期:2013-01-01 00:00:00

  • Long-term surveillance is required for all women treated for cervical adenocarcinoma in situ.

    abstract:OBJECTIVE:To measure the recurrence rate of disease in women treated for cervical adenocarcinoma in situ (ACIS) by either hysterectomy or conservative surgical management. PATIENTS AND METHODS:One hundred patients with a histopathologic diagnosis of ACIS or glandular dysplasia were identified in a retrospective clinic...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/00128360-200404000-00008

    authors: Hwang DM,Lickrish GM,Chapman W,Colgan TJ

    更新日期:2004-04-01 00:00:00

  • Direct visual inspection of the cervix with Lugol iodine for the detection of premalignant lesions.

    abstract:OBJECTIVE:To evaluate the feasibility and efficiency of direct visual inspection after Lugol iodine painting in detecting cervical premalignant and malignant lesions. MATERIALS AND METHODS:This study included 1,012 women recruited from gynecology outpatient clinic screened for premalignant or malignant lesions of the ...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e31815f527c

    authors: El-Shalakany AH,Saeed MM,Abdel-Aal MR,El-Nakeeb AH,Noseirat N,Ayyad SB,El Din ZS

    更新日期:2008-07-01 00:00:00

  • Pseudoepitheliomatous hyperplasia mimicking vulvar cancer in a patient with AIDS.

    abstract:BACKGROUND:Pseudoepitheliomatous hyperplasia (PEH) clinically and histologically mimics squamous cell carcinoma (SCC), specifically in patients with HIV and AIDS. CASE:A 51-year-old G3P2 with AIDS and history of vulvar cancer presented with large bilateral exophytic lesions on the vulva, grossly appearing neoplastic. ...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0b013e3181f0b8f5

    authors: Frimer M,Chudnoff S,Hebert T,Shahabi S

    更新日期:2011-01-01 00:00:00

  • Human Papillomavirus Same Genotype Persistence and Risk: A Systematic Review.

    abstract:OBJECTIVE:The aim of the study was to examine whether high-grade cervical intraepithelial neoplasia (CIN) was more closely associated with human papillomavirus (HPV) same-genotype persistence (SGTP) versus clearance of prior infection with a subsequent infection by a new genotype (genotype switch [GS]), clearance of HP...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000573

    authors: Bonde J,Bottari F,Iacobone AD,Cocuzza CE,Sandri MT,Bogliatto F,Khan KS,Ejegod DM,Gary DS,Andrews JC

    更新日期:2021-01-01 00:00:00

  • Vulvovaginal pyoderma gangrenosum secondary to rituximab therapy.

    abstract::Rituximab is being used increasingly for the treatment of B-cell malignancies and nonmalignant conditions. Pyoderma gangrenosum is a rare neutrophilic dermatosis, which can be either idiopathic or associated with underlying systemic inflammatory conditions. We present a series of 4 patients who presented with ulcerati...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/LGT.0000000000000043

    authors: Dixit S,Selva-Nayagam P,Hamann I,Fischer G

    更新日期:2015-01-01 00:00:00

  • Papanicolaou smears showing atypical glandular cells of undetermined significance: a case series.

    abstract:BACKGROUND:The authors' objective was to determine retrospectively the methods used to follow up atypical glandular cells of undetermined significance (AGUS) on Papanicolaou smears and to evaluate the effectiveness of those methods. MATERIAL AND METHODS:The charts of all patients with AGUS smears obtained between Febr...

    journal_title:Journal of lower genital tract disease

    pub_type: 杂志文章

    doi:10.1097/00128360-199704000-00007

    authors: Landry MS,Julian TM

    更新日期:1997-04-01 00:00:00